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Items: 1 to 50 of 73

1.

Augmentation of iNOS expression in myeloid progenitor cells expedites neutrophil differentiation.

Sadaf S, Singh AK, Awasthi D, Nagarkoti S, Agrahari AK, Srivastava RN, Jagavelu K, Kumar S, Barthwal MK, Dikshit M.

J Leukoc Biol. 2019 Mar 12. doi: 10.1002/JLB.1A0918-349RR. [Epub ahead of print]

PMID:
30861597
2.

Regulation of Monoamine Oxidase B Gene Expression: Key Roles for Transcription Factors Sp1, Egr1 and CREB, and microRNAs miR-300 and miR-1224.

Arige V, Agarwal A, Khan AA, Kalyani A, Natarajan B, Gupta V, Reddy SS, Barthwal MK, Mahapatra NR.

J Mol Biol. 2019 Mar 15;431(6):1127-1147. doi: 10.1016/j.jmb.2019.01.042. Epub 2019 Feb 7.

PMID:
30738894
3.

Total synthesis of the potent anti-inflammatory natural product solomonamide A along with structural revision and biological activity evaluation.

Jachak GR, Athawale PR, Agarwal H, Barthwal MK, Lauro G, Bifulco G, Reddy DS.

Org Biomol Chem. 2018 Dec 5;16(47):9138-9142. doi: 10.1039/c8ob02713g.

PMID:
30478463
4.

Cilostazol ameliorates heart failure with preserved ejection fraction and diastolic dysfunction in obese and non-obese hypertensive mice.

Reddy SS, Agarwal H, Barthwal MK.

J Mol Cell Cardiol. 2018 Oct;123:46-57. doi: 10.1016/j.yjmcc.2018.08.017. Epub 2018 Aug 20.

PMID:
30138626
5.

IL-1 β genesis: the art of regulating the regulator.

Gupta P, Barthwal MK.

Cell Mol Immunol. 2018 Nov;15(11):998-1000. doi: 10.1038/s41423-018-0054-7. Epub 2018 Jun 19. No abstract available.

PMID:
29921967
6.

MicroRNA-99a mimics inhibit M1 macrophage phenotype and adipose tissue inflammation by targeting TNFα.

Jaiswal A, Reddy SS, Maurya M, Maurya P, Barthwal MK.

Cell Mol Immunol. 2019 May;16(5):495-507. doi: 10.1038/s41423-018-0038-7. Epub 2018 May 30.

PMID:
29849090
7.

Anti-thrombotic efficacy of S007-867: Pre-clinical evaluation in experimental models of thrombosis in vivo and in vitro.

Misra A, Prakash P, Aggarwal H, Dhankani P, Kumar S, Pandey CP, Pugh N, Bihan D, Barthwal MK, Farndale RW, Dikshit DK, Dikshit M.

Biochem Pharmacol. 2018 Feb;148:288-297. doi: 10.1016/j.bcp.2018.01.013. Epub 2018 Jan 5. Erratum in: Biochem Pharmacol. 2018 Dec;158:229-231.

PMID:
29309758
8.

Standardized fraction of Xylocarpus moluccensis fruits improve vascular relaxation and plaque stability in dyslipidemic models of atherosclerosis.

Kanshana JS, Rebello SC, Pathak P, Kanuri BN, Aggarwal H, Srivastava V, Khanna V, Singh V, Jagavelu K, Barthwal MK, Dikshit M.

J Ethnopharmacol. 2018 Mar 1;213:81-91. doi: 10.1016/j.jep.2017.11.004. Epub 2017 Nov 10.

PMID:
29129602
9.

Measurement of Aortic Cell Fluid-Phase Pinocytosis in vivo by Flow Cytometry.

Anzinger JJ, Jin X, Palmer CS, Dagur P, Barthwal MK, Kruth HS.

J Vasc Res. 2017;54(4):195-199. doi: 10.1159/000475934. Epub 2017 Jun 16.

10.

Progression and Characterization of the Accelerated Atherosclerosis in Iliac Artery of New Zealand White Rabbits: Effect of Simvastatin.

Kanshana JS, Khanna V, Singh V, Jain M, Misra A, Kumar S, Farooqui M, Barthwal MK, Dikshit M.

J Cardiovasc Pharmacol. 2017 May;69(5):314-325. doi: 10.1097/FJC.0000000000000477.

PMID:
28207427
11.

Nitric oxide-mediated apoptosis of neutrophils through caspase-8 and caspase-3-dependent mechanism.

Dubey M, Nagarkoti S, Awasthi D, Singh AK, Chandra T, Kumaravelu J, Barthwal MK, Dikshit M.

Cell Death Dis. 2016 Sep 1;7(9):e2348. doi: 10.1038/cddis.2016.248.

12.

Coagulin-L ameliorates TLR4 induced oxidative damage and immune response by regulating mitochondria and NOX-derived ROS.

Reddy SS, Chauhan P, Maurya P, Saini D, Yadav PP, Barthwal MK.

Toxicol Appl Pharmacol. 2016 Oct 15;309:87-100. doi: 10.1016/j.taap.2016.08.022. Epub 2016 Aug 26.

PMID:
27568862
13.

A Standardized Chemically Modified Curcuma longa Extract Modulates IRAK-MAPK Signaling in Inflammation and Potentiates Cytotoxicity.

Rana M, Maurya P, Reddy SS, Singh V, Ahmad H, Dwivedi AK, Dikshit M, Barthwal MK.

Front Pharmacol. 2016 Jul 25;7:223. doi: 10.3389/fphar.2016.00223. eCollection 2016.

14.

IRAK regulates macrophage foam cell formation by modulating genes involved in cholesterol uptake and efflux.

Rana M, Kumar A, Tiwari RL, Singh V, Chandra T, Dikshit M, Barthwal MK.

Bioessays. 2016 Jul;38(7):591-604. doi: 10.1002/bies.201600085. Epub 2016 Jun 8.

PMID:
27270491
15.

High oxidative stress adversely affects NFκB mediated induction of inducible nitric oxide synthase in human neutrophils: Implications in chronic myeloid leukemia.

Singh AK, Awasthi D, Dubey M, Nagarkoti S, Kumar A, Chandra T, Barthwal MK, Tripathi AK, Dikshit M.

Nitric Oxide. 2016 Aug 31;58:28-41. doi: 10.1016/j.niox.2016.06.002. Epub 2016 Jun 3.

PMID:
27264783
16.

Synthesis and evaluation of dual antiplatelet activity of bispidine derivatives of N-substituted pyroglutamic acids.

Misra A, Anil Kumar KS, Jain M, Bajaj K, Shandilya S, Srivastava S, Shukla P, Barthwal MK, Dikshit M, Dikshit DK.

Eur J Med Chem. 2016 Mar 3;110:1-12. doi: 10.1016/j.ejmech.2016.01.019. Epub 2016 Jan 18.

PMID:
26807542
17.

Oxidized LDL induced extracellular trap formation in human neutrophils via TLR-PKC-IRAK-MAPK and NADPH-oxidase activation.

Awasthi D, Nagarkoti S, Kumar A, Dubey M, Singh AK, Pathak P, Chandra T, Barthwal MK, Dikshit M.

Free Radic Biol Med. 2016 Apr;93:190-203. doi: 10.1016/j.freeradbiomed.2016.01.004. Epub 2016 Jan 14.

PMID:
26774674
18.

The IRAK-ERK-p67phox-Nox-2 axis mediates TLR4, 2-induced ROS production for IL-1β transcription and processing in monocytes.

Singh A, Singh V, Tiwari RL, Chandra T, Kumar A, Dikshit M, Barthwal MK.

Cell Mol Immunol. 2016 Nov;13(6):745-763. doi: 10.1038/cmi.2015.62. Epub 2015 Aug 31.

19.

Gingerol Inhibits Serum-Induced Vascular Smooth Muscle Cell Proliferation and Injury-Induced Neointimal Hyperplasia by Suppressing p38 MAPK Activation.

Jain M, Singh A, Singh V, Maurya P, Barthwal MK.

J Cardiovasc Pharmacol Ther. 2016 Mar;21(2):187-200. doi: 10.1177/1074248415598003. Epub 2015 Aug 3.

PMID:
26240073
20.

Curcuma oil ameliorates insulin resistance & associated thrombotic complications in hamster & rat.

Singh V, Jain M, Misra A, Khanna V, Prakash P, Malasoni R, Dwivedi AK, Dikshit M, Barthwal MK.

Indian J Med Res. 2015 Jun;141(6):823-32. doi: 10.4103/0971-5916.160719.

21.

Involvement of interleukin-1 receptor-associated kinase-1 in vascular smooth muscle cell proliferation and neointimal formation after rat carotid injury.

Jain M, Singh A, Singh V, Barthwal MK.

Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1445-55. doi: 10.1161/ATVBAHA.114.305028. Epub 2015 Apr 23.

PMID:
25908764
22.

L-Plastin S-glutathionylation promotes reduced binding to β-actin and affects neutrophil functions.

Dubey M, Singh AK, Awasthi D, Nagarkoti S, Kumar S, Ali W, Chandra T, Kumar V, Barthwal MK, Jagavelu K, Sánchez-Gómez FJ, Lamas S, Dikshit M.

Free Radic Biol Med. 2015 Sep;86:1-15. doi: 10.1016/j.freeradbiomed.2015.04.008. Epub 2015 Apr 14.

23.

Cytoprotective and Anti-secretory Effects of Azadiradione Isolated from the Seeds of Azadirachta indica (neem) on Gastric Ulcers in Rat Models.

Singh R, Mishra V, Pandeti S, Palit G, Barthwal MK, Pandey HP, Narender T.

Phytother Res. 2015 Jun;29(6):910-6. doi: 10.1002/ptr.5332. Epub 2015 Apr 8.

PMID:
25851068
24.

Curcuma oil attenuates accelerated atherosclerosis and macrophage foam-cell formation by modulating genes involved in plaque stability, lipid homeostasis and inflammation.

Singh V, Rana M, Jain M, Singh N, Naqvi A, Malasoni R, Dwivedi AK, Dikshit M, Barthwal MK.

Br J Nutr. 2015 Jan 14;113(1):100-13. doi: 10.1017/S0007114514003195. Epub 2014 Nov 13.

PMID:
25391643
25.

PKCδ-IRAK1 axis regulates oxidized LDL-induced IL-1β production in monocytes.

Tiwari RL, Singh V, Singh A, Rana M, Verma A, Kothari N, Kohli M, Bogra J, Dikshit M, Barthwal MK.

J Lipid Res. 2014 Jul;55(7):1226-44. doi: 10.1194/jlr.M045658. Epub 2014 May 2.

26.

Silymarin ameliorates fructose induced insulin resistance syndrome by reducing de novo hepatic lipogenesis in the rat.

Prakash P, Singh V, Jain M, Rana M, Khanna V, Barthwal MK, Dikshit M.

Eur J Pharmacol. 2014 Mar 15;727:15-28. doi: 10.1016/j.ejphar.2014.01.038. Epub 2014 Jan 30.

PMID:
24486395
27.

Cholesterol diet withdrawal leads to an initial plaque instability and subsequent regression of accelerated iliac artery atherosclerosis in rabbits.

Khanna V, Jain M, Singh V, Kanshana JS, Prakash P, Barthwal MK, Murthy PS, Dikshit M.

PLoS One. 2013 Oct 17;8(10):e77037. doi: 10.1371/journal.pone.0077037. eCollection 2013.

28.

Phospholipase C-γ2 via p38 and ERK1/2 MAP kinase mediates diperoxovanadate-asparagine induced human platelet aggregation and sCD40L release.

Misra A, Srivastava S, Ankireddy SR, Islam NS, Chandra T, Kumar A, Barthwal MK, Dikshit M.

Redox Rep. 2013;18(5):174-85. doi: 10.1179/1351000213Y.0000000057. Epub 2013 Jul 23.

PMID:
23883624
29.

Anti-secretory and cyto-protective effects of peganine hydrochloride isolated from the seeds of Peganum harmala on gastric ulcers.

Singh VK, Mishra V, Tiwari S, Khaliq T, Barthwal MK, Pandey HP, Palit G, Narender T.

Phytomedicine. 2013 Oct 15;20(13):1180-5. doi: 10.1016/j.phymed.2013.06.017. Epub 2013 Jul 20.

PMID:
23880327
30.

Interaction of inducible nitric oxide synthase with rac2 regulates reactive oxygen and nitrogen species generation in the human neutrophil phagosomes: implication in microbial killing.

Jyoti A, Singh AK, Dubey M, Kumar S, Saluja R, Keshari RS, Verma A, Chandra T, Kumar A, Bajpai VK, Barthwal MK, Dikshit M.

Antioxid Redox Signal. 2014 Jan 20;20(3):417-31. doi: 10.1089/ars.2012.4970. Epub 2013 Sep 17.

PMID:
23875749
31.

Arbortristoside-A and 7-O-trans-cinnamoyl-6β-hydroxyloganin isolated from Nyctanthes arbortristis possess anti-ulcerogenic and ulcer-healing properties.

Mishra V, Shukla A, Pandeti S, Barthwal MK, Pandey HP, Palit G, Narender T.

Phytomedicine. 2013 Sep 15;20(12):1055-63. doi: 10.1016/j.phymed.2013.04.010. Epub 2013 Jun 7.

PMID:
23746957
32.

Curcuma oil ameliorates hyperlipidaemia and associated deleterious effects in golden Syrian hamsters.

Singh V, Jain M, Misra A, Khanna V, Rana M, Prakash P, Malasoni R, Dwivedi AK, Dikshit M, Barthwal MK.

Br J Nutr. 2013 Aug 28;110(3):437-46. doi: 10.1017/S0007114512005363. Epub 2013 May 15.

PMID:
23673139
33.

Fluid-phase pinocytosis of native low density lipoprotein promotes murine M-CSF differentiated macrophage foam cell formation.

Barthwal MK, Anzinger JJ, Xu Q, Bohnacker T, Wymann MP, Kruth HS.

PLoS One. 2013;8(3):e58054. doi: 10.1371/journal.pone.0058054. Epub 2013 Mar 11.

34.

Antithrombotic activity of a newly synthesized coumarin derivative 3-(5-hydroxy-2,2-dimethyl-chroman-6-yl)-N-{2-[3-(5-hydroxy-2,2-dimethyl-chroman-6-yl)-propionylamino]-ethyl}-propionamide.

Jain M, Surin WR, Misra A, Prakash P, Singh V, Khanna V, Kumar S, Siddiqui HH, Raj K, Barthwal MK, Dikshit M.

Chem Biol Drug Des. 2013 Apr;81(4):499-508. doi: 10.1111/cbdd.12000.

PMID:
23534412
35.

Cytokines induced neutrophil extracellular traps formation: implication for the inflammatory disease condition.

Keshari RS, Jyoti A, Dubey M, Kothari N, Kohli M, Bogra J, Barthwal MK, Dikshit M.

PLoS One. 2012;7(10):e48111. doi: 10.1371/journal.pone.0048111. Epub 2012 Oct 26.

36.

Reactive oxygen species-induced activation of ERK and p38 MAPK mediates PMA-induced NETs release from human neutrophils.

Keshari RS, Verma A, Barthwal MK, Dikshit M.

J Cell Biochem. 2013 Mar;114(3):532-40. doi: 10.1002/jcb.24391.

PMID:
22961925
37.

Role of active nitrogen molecules in progression of septic shock.

Kothari N, Bogra J, Kohli M, Malik A, Kothari D, Srivastava S, Keshari RS, Singh V, Barthwal MK, Dikshit M.

Acta Anaesthesiol Scand. 2012 Mar;56(3):307-15. doi: 10.1111/j.1399-6576.2011.02607.x. Epub 2011 Dec 23.

PMID:
22192332
38.

Neutrophil extracellular traps contain mitochondrial as well as nuclear DNA and exhibit inflammatory potential.

Keshari RS, Jyoti A, Kumar S, Dubey M, Verma A, Srinag BS, Krishnamurthy H, Barthwal MK, Dikshit M.

Cytometry A. 2012 Mar;81(3):238-47. doi: 10.1002/cyto.a.21178. Epub 2011 Dec 13.

39.

Synthesis and pharmacological evaluation of novel arginine analogs as potential inhibitors of acetylcholine-induced relaxation in rat thoracic aortic rings.

Jain M, Barthwal MK, Haq W, Katti SB, Dikshit M.

Chem Biol Drug Des. 2012 Apr;79(4):459-69. doi: 10.1111/j.1747-0285.2011.01286.x. Epub 2012 Jan 30.

PMID:
22145586
40.

Murine bone marrow-derived macrophages differentiated with GM-CSF become foam cells by PI3Kγ-dependent fluid-phase pinocytosis of native LDL.

Anzinger JJ, Chang J, Xu Q, Barthwal MK, Bohnacker T, Wymann MP, Kruth HS.

J Lipid Res. 2012 Jan;53(1):34-42. doi: 10.1194/jlr.M018887. Epub 2011 Nov 4.

41.

IL-1R-associated kinase-1 mediates protein kinase Cδ-induced IL-1β production in monocytes.

Tiwari RL, Singh V, Singh A, Barthwal MK.

J Immunol. 2011 Sep 1;187(5):2632-45. doi: 10.4049/jimmunol.1002526. Epub 2011 Jul 29.

42.

Molecular and biochemical characterization of nitric oxide synthase isoforms and their intracellular distribution in human peripheral blood mononuclear cells.

Saluja R, Jyoti A, Chatterjee M, Habib S, Verma A, Mitra K, Barthwal MK, Bajpai VK, Dikshit M.

Biochim Biophys Acta. 2011 Oct;1813(10):1700-7. doi: 10.1016/j.bbamcr.2011.06.008. Epub 2011 Jun 23.

43.

Atorvastatin protects against ischemia-reperfusion injury in fructose-induced insulin resistant rats.

Prakash P, Khanna V, Singh V, Jyoti A, Jain M, Keshari RS, Barthwal MK, Dikshit M.

Cardiovasc Drugs Ther. 2011 Aug;25(4):285-97. doi: 10.1007/s10557-011-6312-x.

PMID:
21671014
44.

Vasomodulatory effect of novel peroxovanadate compounds on rat aorta: Role of rho kinase and nitric oxide/cGMP pathway.

Khanna V, Jain M, Barthwal MK, Kalita D, Boruah JJ, Das SP, Islam NS, Ramasarma T, Dikshit M.

Pharmacol Res. 2011 Sep;64(3):274-82. doi: 10.1016/j.phrs.2011.03.016. Epub 2011 Apr 7.

PMID:
21497197
45.

Nitrite-mediated modulation of HL-60 cell cycle and proliferation: involvement of cyclin-dependent kinase 2 activation.

Kumar S, Barthwal MK, Dikshit M.

J Pharmacol Exp Ther. 2011 Jun;337(3):812-21. doi: 10.1124/jpet.110.177444. Epub 2011 Mar 16.

PMID:
21411497
46.

A time course study on prothrombotic parameters and their modulation by anti-platelet drugs in hyperlipidemic hamsters.

Singh V, Jain M, Prakash P, Misra A, Khanna V, Tiwari RL, Keshari RS, Singh S, Dikshit M, Barthwal MK.

J Physiol Biochem. 2011 Jun;67(2):205-16. doi: 10.1007/s13105-010-0065-z. Epub 2011 Feb 1.

PMID:
21286889
47.

Anti-platelet effects of Curcuma oil in experimental models of myocardial ischemia-reperfusion and thrombosis.

Prakash P, Misra A, Surin WR, Jain M, Bhatta RS, Pal R, Raj K, Barthwal MK, Dikshit M.

Thromb Res. 2011 Feb;127(2):111-8. doi: 10.1016/j.thromres.2010.11.007. Epub 2010 Dec 8.

PMID:
21144557
48.

Increased myeloperoxidase enzyme activity in plasma is an indicator of inflammation and onset of sepsis.

Kothari N, Keshari RS, Bogra J, Kohli M, Abbas H, Malik A, Dikshit M, Barthwal MK.

J Crit Care. 2011 Aug;26(4):435.e1-7. doi: 10.1016/j.jcrc.2010.09.001. Epub 2010 Oct 30.

PMID:
21036525
49.

Nitric oxide-mediated augmentation of neutrophil reactive oxygen and nitrogen species formation: Critical use of probes.

Kumar S, Patel S, Jyoti A, Keshari RS, Verma A, Barthwal MK, Dikshit M.

Cytometry A. 2010 Nov;77(11):1038-48. doi: 10.1002/cyto.a.20975.

50.

Ramipril-like activity of Spondias mombin linn against no-flow ischemia and isoproterenol-induced cardiotoxicity in rat heart.

Akinmoladun AC, Obuotor EM, Barthwal MK, Dikshit M, Farombi EO.

Cardiovasc Toxicol. 2010 Dec;10(4):295-305. doi: 10.1007/s12012-010-9089-4.

PMID:
20872093

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