Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 42

1.

miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2.

Fuentes-Mattei E, Bayraktar R, Manshouri T, Silva AM, Ivan C, Gulei D, Fabris L, Soares do Amaral N, Mur P, Perez C, Torres-Claudio E, Dragomir MP, Badillo-Perez A, Knutsen E, Narayanan P, Golfman L, Shimizu M, Zhang X, Zhao W, Ho WT, Estecio MR, Bartholomeusz G, Tomuleasa C, Berindan-Neagoe I, Zweidler-McKay PA, Estrov Z, Zhao ZJ, Verstovsek S, Calin GA, Redis RS.

JCI Insight. 2020 Jan 16;5(1). pii: 121781. doi: 10.1172/jci.insight.121781.

2.

6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase-2 Regulates TP53-Dependent Paclitaxel Sensitivity in Ovarian and Breast Cancers.

Yang H, Shu Z, Jiang Y, Mao W, Pang L, Redwood A, Jeter-Jones SL, Jennings NB, Ornelas A, Zhou J, Rodriguez-Aguayo C, Bartholomeusz G, Iles LR, Zacharias NM, Millward SW, Lopez-Berestein G, Le XF, Ahmed AA, Piwnica-Worms H, Sood AK, Bast RC, Lu Z.

Clin Cancer Res. 2019 Sep 15;25(18):5702-5716. doi: 10.1158/1078-0432.CCR-18-3448. Epub 2019 Aug 7.

PMID:
31391192
3.

PRKRA/PACT Expression Promotes Chemoresistance of Mucinous Ovarian Cancer.

Hisamatsu T, McGuire M, Wu SY, Rupaimoole R, Pradeep S, Bayraktar E, Noh K, Hu W, Hansen JM, Lyons Y, Gharpure KM, Nagaraja AS, Mangala LS, Mitamura T, Rodriguez-Aguayo C, Eun YG, Rose J, Bartholomeusz G, Ivan C, Lee JS, Matsuo K, Frumovitz M, Wong KK, Lopez-Berestein G, Sood AK.

Mol Cancer Ther. 2019 Jan;18(1):162-172. doi: 10.1158/1535-7163.MCT-17-1050. Epub 2018 Oct 10.

4.

Paclitaxel Sensitivity of Ovarian Cancer Can be Enhanced by Knocking Down Pairs of Kinases that Regulate MAP4 Phosphorylation and Microtubule Stability.

Yang H, Mao W, Rodriguez-Aguayo C, Mangala LS, Bartholomeusz G, Iles LR, Jennings NB, Ahmed AA, Sood AK, Lopez-Berestein G, Lu Z, Bast RC Jr.

Clin Cancer Res. 2018 Oct 15;24(20):5072-5084. doi: 10.1158/1078-0432.CCR-18-0504. Epub 2018 Jul 3.

5.

Clinically relevant inflammatory breast cancer patient-derived xenograft-derived ex vivo model for evaluation of tumor-specific therapies.

Eckhardt BL, Gagliardi M, Iles L, Evans K, Ivan C, Liu X, Liu CG, Souza G, Rao A, Meric-Bernstam F, Ueno NT, Bartholomeusz GA.

PLoS One. 2018 May 16;13(5):e0195932. doi: 10.1371/journal.pone.0195932. eCollection 2018.

6.

Aspergillus candidus is a newly recognized source of sphaeropsidin A: Isolation, semi-synthetic derivatization and anticancer evaluation.

Li Y, Scott R, Hooper AR, Bartholomeusz GA, Kornienko A, Bills GF.

Bioorg Med Chem Lett. 2017 Dec 15;27(24):5436-5440. doi: 10.1016/j.bmcl.2017.11.001. Epub 2017 Nov 4.

PMID:
29138030
7.

Genome-wide siRNA screen identifies UNC50 as a regulator of Shiga toxin 2 trafficking.

Selyunin AS, Iles LR, Bartholomeusz G, Mukhopadhyay S.

J Cell Biol. 2017 Oct 2;216(10):3249-3262. doi: 10.1083/jcb.201704015. Epub 2017 Sep 7.

8.

Anti-Cryptococcus Phenalenones and Cyclic Tetrapeptides from Auxarthron pseudauxarthron.

Li Y, Yue Q, Jayanetti DR, Swenson DC, Bartholomeusz GA, An Z, Gloer JB, Bills GF.

J Nat Prod. 2017 Jul 28;80(7):2101-2109. doi: 10.1021/acs.jnatprod.7b00341. Epub 2017 Jun 28.

9.

Loss of PFKFB4 induces cell death in mitotically arrested ovarian cancer cells.

Taylor C, Mannion D, Miranda F, Karaminejadranjbar M, Herrero-Gonzalez S, Hellner K, Zheng Y, Bartholomeusz G, Bast RC Jr, Ahmed AA.

Oncotarget. 2017 Mar 14;8(11):17960-17980. doi: 10.18632/oncotarget.14910.

10.

Benzophenone and Fimetarone Derivatives from the Coprophilous Fungus Delitschia confertaspora.

Jayanetti DR, Li Y, Bartholomeusz GA, Bills GF, Gloer JB.

J Nat Prod. 2017 Mar 24;80(3):707-712. doi: 10.1021/acs.jnatprod.6b01091. Epub 2017 Jan 27.

PMID:
28128947
11.

H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer.

Ohtsuka M, Ling H, Ivan C, Pichler M, Matsushita D, Goblirsch M, Stiegelbauer V, Shigeyasu K, Zhang X, Chen M, Vidhu F, Bartholomeusz GA, Toiyama Y, Kusunoki M, Doki Y, Mori M, Song S, Gunther JR, Krishnan S, Slaby O, Goel A, Ajani JA, Radovich M, Calin GA.

EBioMedicine. 2016 Nov;13:113-124. doi: 10.1016/j.ebiom.2016.10.026. Epub 2016 Oct 19.

12.

Corrigendum to "Synthesis and cytotoxic activity of novel A-ring cleaved ursolic acid derivatives in human non-small cell lung cancer cells" [Eur. J. Med. Chem. 123 (2016) 317-331].

Mendes VIS, Bartholomeusz GA, Ayres M, Gandhi V, Salvador JAR.

Eur J Med Chem. 2016 Nov 29;124:1004-1005. doi: 10.1016/j.ejmech.2016.09.088. Epub 2016 Oct 23. No abstract available.

13.

Three-Dimensional Spheroid Cell Culture Model for Target Identification Utilizing High-Throughput RNAi Screens.

Iles LR, Bartholomeusz GA.

Methods Mol Biol. 2016;1470:121-35. doi: 10.1007/978-1-4939-6337-9_10.

PMID:
27581289
14.

Synthesis and cytotoxic activity of novel A-ring cleaved ursolic acid derivatives in human non-small cell lung cancer cells.

Mendes VIS, Bartholomeusz GA, Ayres M, Gandhi V, Salvador JAR.

Eur J Med Chem. 2016 Nov 10;123:317-331. doi: 10.1016/j.ejmech.2016.07.045. Epub 2016 Jul 22. Erratum in: Eur J Med Chem. 2016 Nov 29;124:1004-1005.

15.

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.

Redis RS, Vela LE, Lu W, Ferreira de Oliveira J, Ivan C, Rodriguez-Aguayo C, Adamoski D, Pasculli B, Taguchi A, Chen Y, Fernandez AF, Valledor L, Van Roosbroeck K, Chang S, Shah M, Kinnebrew G, Han L, Atlasi Y, Cheung LH, Huang GY, Monroig P, Ramirez MS, Catela Ivkovic T, Van L, Ling H, Gafà R, Kapitanovic S, Lanza G, Bankson JA, Huang P, Lai SY, Bast RC, Rosenblum MG, Radovich M, Ivan M, Bartholomeusz G, Liang H, Fraga MF, Widger WR, Hanash S, Berindan-Neagoe I, Lopez-Berestein G, Ambrosio ALB, Gomes Dias SM, Calin GA.

Mol Cell. 2016 Feb 18;61(4):640. doi: 10.1016/j.molcel.2016.02.006. Epub 2016 Feb 18. No abstract available.

16.

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.

Redis RS, Vela LE, Lu W, Ferreira de Oliveira J, Ivan C, Rodriguez-Aguayo C, Adamoski D, Pasculli B, Taguchi A, Chen Y, Fernandez AF, Valledor L, Van Roosbroeck K, Chang S, Shah M, Kinnebrew G, Han L, Atlasi Y, Cheung LH, Huang GY, Monroig P, Ramirez MS, Catela Ivkovic T, Van L, Ling H, Gafà R, Kapitanovic S, Lanza G, Bankson JA, Huang P, Lai SY, Bast RC, Rosenblum MG, Radovich M, Ivan M, Bartholomeusz G, Liang H, Fraga MF, Widger WR, Hanash S, Berindan-Neagoe I, Lopez-Berestein G, Ambrosio ALB, Gomes Dias SM, Calin GA.

Mol Cell. 2016 Feb 18;61(4):520-534. doi: 10.1016/j.molcel.2016.01.015. Epub 2016 Feb 4. Erratum in: Mol Cell. 2016 Feb 18;61(4):640.

17.

Comprehensive Two- and Three-Dimensional RNAi Screening Identifies PI3K Inhibition as a Complement to MEK Inhibitor AS703026 for Combination Treatment of Triple-Negative Breast Cancer.

Lee J, Galloway R, Grandjean G, Jacob J, Humphries J, Bartholomeusz C, Goodstal S, Lim B, Bartholomeusz G, Ueno NT, Rao A.

J Cancer. 2015 Oct 28;6(12):1306-19. doi: 10.7150/jca.13266. eCollection 2015.

18.

The ZNF304-integrin axis protects against anoikis in cancer.

Aslan B, Monroig P, Hsu MC, Pena GA, Rodriguez-Aguayo C, Gonzalez-Villasana V, Rupaimoole R, Nagaraja AS, Mangala S, Han HD, Yuca E, Wu SY, Ivan C, Moss TJ, Ram PT, Wang H, Gol-Chambers A, Ozkayar O, Kanlikilicer P, Fuentes-Mattei E, Kahraman N, Pradeep S, Ozpolat B, Tucker S, Hung MC, Baggerly K, Bartholomeusz G, Calin G, Sood AK, Lopez-Berestein G.

Nat Commun. 2015 Jun 17;6:7351. doi: 10.1038/ncomms8351.

19.

3D tissue-engineered model of Ewing's sarcoma.

Lamhamedi-Cherradi SE, Santoro M, Ramammoorthy V, Menegaz BA, Bartholomeusz G, Iles LR, Amin HM, Livingston JA, Mikos AG, Ludwig JA.

Adv Drug Deliv Rev. 2014 Dec 15;79-80:155-71. doi: 10.1016/j.addr.2014.07.012. Epub 2014 Aug 7. Review.

20.

KEAP1-dependent synthetic lethality induced by AKT and TXNRD1 inhibitors in lung cancer.

Dai B, Yoo SY, Bartholomeusz G, Graham RA, Majidi M, Yan S, Meng J, Ji L, Coombes K, Minna JD, Fang B, Roth JA.

Cancer Res. 2013 Sep 1;73(17):5532-43. doi: 10.1158/0008-5472.CAN-13-0712. Epub 2013 Jul 3.

21.

Hypoxia triggers hedgehog-mediated tumor-stromal interactions in pancreatic cancer.

Spivak-Kroizman TR, Hostetter G, Posner R, Aziz M, Hu C, Demeure MJ, Von Hoff D, Hingorani SR, Palculict TB, Izzo J, Kiriakova GM, Abdelmelek M, Bartholomeusz G, James BP, Powis G.

Cancer Res. 2013 Jun 1;73(11):3235-47. doi: 10.1158/0008-5472.CAN-11-1433. Epub 2013 Apr 30.

22.

Carbon Nanotubes: Solution for the Therapeutic Delivery of siRNA?

Kirkpatrick DL, Weiss M, Naumov A, Bartholomeusz G, Weisman RB, Gliko O.

Materials (Basel). 2012 Feb 13;5(2):278-301. doi: 10.3390/ma5020278.

23.

Imexon induces an oxidative endoplasmic reticulum stress response in pancreatic cancer cells.

Sheveleva EV, Landowski TH, Samulitis BK, Bartholomeusz G, Powis G, Dorr RT.

Mol Cancer Res. 2012 Mar;10(3):392-400. doi: 10.1158/1541-7786.MCR-11-0359. Epub 2012 Jan 24.

24.

Modulating microtubule stability enhances the cytotoxic response of cancer cells to Paclitaxel.

Ahmed AA, Wang X, Lu Z, Goldsmith J, Le XF, Grandjean G, Bartholomeusz G, Broom B, Bast RC Jr.

Cancer Res. 2011 Sep 1;71(17):5806-17. doi: 10.1158/0008-5472.CAN-11-0025. Epub 2011 Jul 20.

25.

Essential attributes identified in the design of a Laboratory Information Management System for a high throughput siRNA screening laboratory.

Grandjean G, Graham R, Bartholomeusz G.

Comb Chem High Throughput Screen. 2011 Nov;14(9):766-71.

PMID:
21631413
26.

Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis.

Sun H, Kapuria V, Peterson LF, Fang D, Bornmann WG, Bartholomeusz G, Talpaz M, Donato NJ.

Blood. 2011 Mar 17;117(11):3151-62. doi: 10.1182/blood-2010-03-276477. Epub 2011 Jan 19.

PMID:
21248063
27.

SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer.

Ahmed AA, Lu Z, Jennings NB, Etemadmoghadam D, Capalbo L, Jacamo RO, Barbosa-Morais N, Le XF; Australian Ovarian Cancer Study Group, Vivas-Mejia P, Lopez-Berestein G, Grandjean G, Bartholomeusz G, Liao W, Andreeff M, Bowtell D, Glover DM, Sood AK, Bast RC Jr.

Cancer Cell. 2010 Aug 9;18(2):109-21. doi: 10.1016/j.ccr.2010.06.018.

28.

In Vivo Therapeutic Silencing of Hypoxia-Inducible Factor 1 Alpha (HIF-1α) Using Single-Walled Carbon Nanotubes Noncovalently Coated with siRNA.

Bartholomeusz G, Cherukuri P, Kingston J, Cognet L, Lemos R, Leeuw TK, Gumbiner-Russo L, Weisman RB, Powis G.

Nano Res. 2009 Apr 17;2(4):279-291.

29.

Degrasyn activates proteasomal-dependent degradation of c-Myc.

Bartholomeusz G, Talpaz M, Bornmann W, Kong LY, Donato NJ.

Cancer Res. 2007 Apr 15;67(8):3912-8.

30.

Activation of a novel Bcr/Abl destruction pathway by WP1130 induces apoptosis of chronic myelogenous leukemia cells.

Bartholomeusz GA, Talpaz M, Kapuria V, Kong LY, Wang S, Estrov Z, Priebe W, Wu J, Donato NJ.

Blood. 2007 Apr 15;109(8):3470-8. Epub 2007 Jan 3.

31.

Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin beta1 and CRM1.

Lo HW, Ali-Seyed M, Wu Y, Bartholomeusz G, Hsu SC, Hung MC.

J Cell Biochem. 2006 Aug 15;98(6):1570-83.

PMID:
16552725
32.

Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor.

Giri DK, Ali-Seyed M, Li LY, Lee DF, Ling P, Bartholomeusz G, Wang SC, Hung MC.

Mol Cell Biol. 2005 Dec;25(24):11005-18.

33.

Nuclear translocation of the pro-apoptotic Bcl-2 family member Bok induces apoptosis.

Bartholomeusz G, Wu Y, Ali Seyed M, Xia W, Kwong KY, Hortobagyi G, Hung MC.

Mol Carcinog. 2006 Feb;45(2):73-83.

PMID:
16302269
34.

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.

Ding Q, Xia W, Liu JC, Yang JY, Lee DF, Xia J, Bartholomeusz G, Li Y, Pan Y, Li Z, Bargou RC, Qin J, Lai CC, Tsai FJ, Tsai CH, Hung MC.

Mol Cell. 2005 Jul 22;19(2):159-70.

35.

Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway.

Lo HW, Hsu SC, Ali-Seyed M, Gunduz M, Xia W, Wei Y, Bartholomeusz G, Shih JY, Hung MC.

Cancer Cell. 2005 Jun;7(6):575-89.

36.

Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2.

Wang SC, Lien HC, Xia W, Chen IF, Lo HW, Wang Z, Ali-Seyed M, Lee DF, Bartholomeusz G, Ou-Yang F, Giri DK, Hung MC.

Cancer Cell. 2004 Sep;6(3):251-61.

38.

The highly conserved protein methyltransferase, Skb1, is a mediator of hyperosmotic stress response in the fission yeast Schizosaccharomyces pombe.

Bao S, Qyang Y, Yang P, Kim H, Du H, Bartholomeusz G, Henkel J, Pimental R, Verde F, Marcus S.

J Biol Chem. 2001 May 4;276(18):14549-52. Epub 2001 Mar 9.

39.

HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway.

Wen Y, Hu MC, Makino K, Spohn B, Bartholomeusz G, Yan DH, Hung MC.

Cancer Res. 2000 Dec 15;60(24):6841-5.

40.

Direct binding and In vivo regulation of the fission yeast p21-activated kinase shk1 by the SH3 domain protein scd2.

Chang E, Bartholomeusz G, Pimental R, Chen J, Lai H, Wang Lh, Yang P, Marcus S.

Mol Cell Biol. 1999 Dec;19(12):8066-74.

41.

Negative regulation of mitosis in fission yeast by the shk1 interacting protein skb1 and its human homolog, Skb1Hs.

Gilbreth M, Yang P, Bartholomeusz G, Pimental RA, Kansra S, Gadiraju R, Marcus S.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14781-6.

42.

Supplemental Content

Loading ...
Support Center