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Items: 1 to 50 of 119

1.

Evaluation of 11C-LSN3172176 as a novel PET tracer for imaging M1 muscarinic acetylcholine receptors in non-human primates.

Nabulsi NB, Holden D, Zheng MQ, Bois F, Lin SF, Najafzadeh S, Gao H, Ropchan J, Lara-Jaime T, Labaree D, Shirali A, Slieker LJ, Jesudason CD, Barth VN, Navarro A, Kant N, Carson RE, Huang H.

J Nucl Med. 2019 Feb 7. pii: jnumed.118.222034. doi: 10.2967/jnumed.118.222034. [Epub ahead of print]

PMID:
30733324
2.

Shifting Instead of Drifting - Improving Attentional Performance by Means of the Attention Training Technique.

Barth V, Heitland I, Kruger THC, Kahl KG, Sinke C, Winter L.

Front Psychol. 2019 Jan 23;10:23. doi: 10.3389/fpsyg.2019.00023. eCollection 2019.

3.

Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant agonist at muscarinic M1 receptors.

Broad LM, Sanger HE, Mogg AJ, Colvin EM, Zwart R, Evans DA, Pasqui F, Sher E, Wishart GN, Barth VN, Felder CC, Goldsmith PJ.

Br J Pharmacol. 2019 Jan;176(1):110-126. doi: 10.1111/bph.14510. Epub 2018 Nov 16.

PMID:
30276808
4.

Evaluation of a PET Radioligand to Image O-GlcNAcase in Brain and Periphery of Rhesus Monkey and Knock-Out Mouse.

Paul S, Haskali MB, Liow JS, Zoghbi SS, Barth VN, Kolodrubetz MC, Bond MR, Morse CL, Gladding RL, Frankland MP, Kant N, Slieker L, Shcherbinin S, Nuthall HN, Zanotti-Fregonara P, Hanover JA, Jesudason C, Pike VW, Innis RB.

J Nucl Med. 2019 Jan;60(1):129-134. doi: 10.2967/jnumed.118.213231. Epub 2018 Sep 13.

PMID:
30213846
5.

Antimicrobial efficacy of 0.5% peracetic acid and EDTA with passive ultrasonic or manual agitation in an Enterococcus faecalis biofilm model.

Hartmann RC, Neuvald L, Barth V Jr, de Figueiredo JAP, de Oliveira SD, Scarparo RK, Waltrick SB, Rossi-Fedele G.

Aust Endod J. 2018 Aug 13. doi: 10.1111/aej.12279. [Epub ahead of print]

PMID:
30105835
6.

In Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission Tomography.

Mogg AJ, Eessalu T, Johnson M, Wright R, Sanger HE, Xiao H, Crabtree MG, Smith A, Colvin EM, Schober D, Gehlert D, Jesudason C, Goldsmith PJ, Johnson MP, Felder CC, Barth VN, Broad LM.

J Pharmacol Exp Ther. 2018 Jun;365(3):602-613. doi: 10.1124/jpet.117.246454. Epub 2018 Apr 11.

PMID:
29643252
7.

Pseudoreference Regions for Glial Imaging with 11C-PBR28: Investigation in 2 Clinical Cohorts.

Albrecht DS, Normandin MD, Shcherbinin S, Wooten DW, Schwarz AJ, Zürcher NR, Barth VN, Guehl NJ, Akeju O, Atassi N, Veronese M, Turkheimer F, Hooker JM, Loggia ML.

J Nucl Med. 2018 Jan;59(1):107-114. doi: 10.2967/jnumed.116.178335. Epub 2017 Aug 17.

8.

Energy-Level Alignment of a Hole-Transport Organic Layer and ITO: Toward Applications for Organic Electronic Devices.

Arnoux Q, Boucly A, Barth V, Benbalagh R, Cossaro A, Floreano L, Silly M, Sirotti F, Derat E, Carniato S, Bournel F, Gallet JJ, Fichou D, Tortech L, Rochet F.

ACS Appl Mater Interfaces. 2017 Sep 13;9(36):30992-31004. doi: 10.1021/acsami.7b06691. Epub 2017 Aug 31.

PMID:
28805058
9.

In Vivo Receptor Occupancy in Rodents by LC-MS/MS.

Jesudason CD, DuBois S, Johnson M, Barth VN, Need AB.

In: Sittampalam GS, Coussens NP, Brimacombe K, Grossman A, Arkin M, Auld D, Austin C, Baell J, Bejcek B, Caaveiro JMM, Chung TDY, Dahlin JL, Devanaryan V, Foley TL, Glicksman M, Hall MD, Haas JV, Inglese J, Iversen PW, Kahl SD, Kales SC, Lal-Nag M, Li Z, McGee J, McManus O, Riss T, Trask OJ Jr., Weidner JR, Wildey MJ, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-.
2017 Mar 9.

10.

Preclinical findings predicting efficacy and side-effect profile of LY2940094, an antagonist of nociceptin receptors.

Witkin JM, Rorick-Kehn LM, Benvenga MJ, Adams BL, Gleason SD, Knitowski KM, Li X, Chaney S, Falcone JF, Smith JW, Foss J, Lloyd K, Catlow JT, McKinzie DL, Svensson KA, Barth VN, Toledo MA, Diaz N, Lafuente C, Jiménez A, Benito A, Pedregal C, Martínez-Grau MA, Post A, Ansonoff MA, Pintar JE, Statnick MA.

Pharmacol Res Perspect. 2016 Nov 7;4(6):e00275. doi: 10.1002/prp2.275. eCollection 2016 Dec.

11.

Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects.

Raddad E, Chappell A, Meyer J, Wilson A, Ruegg CE, Tauscher J, Statnick MA, Barth V, Zhang X, Verfaille SJ.

Drug Metab Dispos. 2016 Sep;44(9):1536-42. doi: 10.1124/dmd.116.070359. Epub 2016 Jun 27.

PMID:
27353045
12.

Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8.

Gardinier KM, Gernert DL, Porter WJ, Reel JK, Ornstein PL, Spinazze P, Stevens FC, Hahn P, Hollinshead SP, Mayhugh D, Schkeryantz J, Khilevich A, De Frutos O, Gleason SD, Kato AS, Luffer-Atlas D, Desai PV, Swanson S, Burris KD, Ding C, Heinz BA, Need AB, Barth VN, Stephenson GA, Diseroad BA, Woods TA, Yu H, Bredt D, Witkin JM.

J Med Chem. 2016 May 26;59(10):4753-68. doi: 10.1021/acs.jmedchem.6b00125. Epub 2016 Apr 29.

PMID:
27067148
13.

Detection and quantification of viable Bacillus cereus group species in milk by propidium monoazide quantitative real-time PCR.

Cattani F, Barth VC Jr, Nasário JSR, Ferreira CAS, Oliveira SD.

J Dairy Sci. 2016 Apr;99(4):2617-2624. doi: 10.3168/jds.2015-10019. Epub 2016 Jan 29.

14.

A Selective Nociceptin Receptor Antagonist to Treat Depression: Evidence from Preclinical and Clinical Studies.

Post A, Smart TS, Krikke-Workel J, Dawson GR, Harmer CJ, Browning M, Jackson K, Kakar R, Mohs R, Statnick M, Wafford K, McCarthy A, Barth V, Witkin JM.

Neuropsychopharmacology. 2016 Jun;41(7):1803-12. doi: 10.1038/npp.2015.348. Epub 2015 Nov 20.

15.

Characterization of antimicrobial resistance in Salmonella enterica strains isolated from Brazilian poultry production.

Mattiello SP, Drescher G, Barth VC Jr, Ferreira CA, Oliveira SD.

Antonie Van Leeuwenhoek. 2015 Nov;108(5):1227-38. doi: 10.1007/s10482-015-0577-1. Epub 2015 Sep 3.

PMID:
26337044
16.

123I-iododexetimide preferentially binds to the muscarinic receptor subtype M1 in vivo.

Bakker G, Vingerhoets WA, van Wieringen JP, de Bruin K, Eersels J, de Jong J, Chahid Y, Rutten BP, DuBois S, Watson M, Mogg AJ, Xiao H, Crabtree M, Collier DA, Felder CC, Barth VN, Broad LM, Bloemen OJ, van Amelsvoort TA, Booij J.

J Nucl Med. 2015 Feb;56(2):317-22. doi: 10.2967/jnumed.114.147488. Epub 2015 Jan 15.

17.

Efficiency gains in tracer identification for nuclear imaging: can in vivo LC-MS/MS evaluation of small molecules screen for successful PET tracers?

Joshi EM, Need A, Schaus J, Chen Z, Benesh D, Mitch C, Morton S, Raub TJ, Phebus L, Barth V.

ACS Chem Neurosci. 2014 Dec 17;5(12):1154-63. doi: 10.1021/cn500073j. Epub 2014 Oct 13. Review.

PMID:
25247893
18.

An Improved Antagonist Radiotracer for the κ-Opioid Receptor: Synthesis and Characterization of (11)C-LY2459989.

Zheng MQ, Kim SJ, Holden D, Lin SF, Need A, Rash K, Barth V, Mitch C, Navarro A, Kapinos M, Maloney K, Ropchan J, Carson RE, Huang Y.

J Nucl Med. 2014 Jul;55(7):1185-91. doi: 10.2967/jnumed.114.138701. Epub 2014 May 22.

19.

Identifying novel radiotracers for PET imaging of the brain: application of LC-MS/MS to tracer identification.

Barth V, Need A.

ACS Chem Neurosci. 2014 Dec 17;5(12):1148-53. doi: 10.1021/cn500072r. Epub 2014 May 28. Review.

PMID:
24828747
20.

Discovery of a novel series of orally active nociceptin/orphanin FQ (NOP) receptor antagonists based on a dihydrospiro(piperidine-4,7'-thieno[2,3-c]pyran) scaffold.

Toledo MA, Pedregal C, Lafuente C, Diaz N, Martinez-Grau MA, Jiménez A, Benito A, Torrado A, Mateos C, Joshi EM, Kahl SD, Rash KS, Mudra DR, Barth VN, Shaw DB, McKinzie D, Witkin JM, Statnick MA.

J Med Chem. 2014 Apr 24;57(8):3418-29. doi: 10.1021/jm500117r. Epub 2014 Apr 11.

PMID:
24678969
21.

Heterogeneous persister cells formation in Acinetobacter baumannii.

Barth VC Jr, Rodrigues BÁ, Bonatto GD, Gallo SW, Pagnussatti VE, Ferreira CA, de Oliveira SD.

PLoS One. 2013 Dec 31;8(12):e84361. doi: 10.1371/journal.pone.0084361. eCollection 2013.

22.

Design, synthesis, and evaluation of hydroxamic acid-based molecular probes for in vivo imaging of histone deacetylase (HDAC) in brain.

Wang C, Eessalu TE, Barth VN, Mitch CH, Wagner FF, Hong Y, Neelamegam R, Schroeder FA, Holson EB, Haggarty SJ, Hooker JM.

Am J Nucl Med Mol Imaging. 2013 Dec 15;4(1):29-38. eCollection 2013.

23.

Retest imaging of [11C]NOP-1A binding to nociceptin/orphanin FQ peptide (NOP) receptors in the brain of healthy humans.

Lohith TG, Zoghbi SS, Morse CL, Araneta MD, Barth VN, Goebl NA, Tauscher JT, Pike VW, Innis RB, Fujita M.

Neuroimage. 2014 Feb 15;87:89-95. doi: 10.1016/j.neuroimage.2013.10.068. Epub 2013 Nov 10.

24.

11C-LY2428703, a positron emission tomographic radioligand for the metabotropic glutamate receptor 1, is unsuitable for imaging in monkey and human brains.

Zanotti-Fregonara P, Barth VN, Zoghbi SS, Liow JS, Nisenbaum E, Siuda E, Gladding RL, Rallis-Frutos D, Morse C, Tauscher J, Pike VW, Innis RB.

EJNMMI Res. 2013 Jun 10;3(1):47. doi: 10.1186/2191-219X-3-47.

25.

Synthesis and evaluation of 11C-LY2795050 as a κ-opioid receptor antagonist radiotracer for PET imaging.

Zheng MQ, Nabulsi N, Kim SJ, Tomasi G, Lin SF, Mitch C, Quimby S, Barth V, Rash K, Masters J, Navarro A, Seest E, Morris ED, Carson RE, Huang Y.

J Nucl Med. 2013 Mar;54(3):455-63. doi: 10.2967/jnumed.112.109512. Epub 2013 Jan 25.

26.

In vivo occupancy of dopamine D3 receptors by antagonists produces neurochemical and behavioral effects of potential relevance to attention-deficit-hyperactivity disorder.

Barth V, Need AB, Tzavara ET, Giros B, Overshiner C, Gleason SD, Wade M, Johansson AM, Perry K, Nomikos GG, Witkin JM.

J Pharmacol Exp Ther. 2013 Feb;344(2):501-10. doi: 10.1124/jpet.112.198895. Epub 2012 Nov 29.

PMID:
23197772
27.

Evaluation in vitro and in animals of a new 11C-labeled PET radioligand for metabotropic glutamate receptors 1 in brain.

Zanotti-Fregonara P, Barth VN, Liow JS, Zoghbi SS, Clark DT, Rhoads E, Siuda E, Heinz BA, Nisenbaum E, Dressman B, Joshi E, Luffer-Atlas D, Fisher MJ, Masters JJ, Goebl N, Kuklish SL, Morse C, Tauscher J, Pike VW, Innis RB.

Eur J Nucl Med Mol Imaging. 2013 Jan;40(2):245-53. doi: 10.1007/s00259-012-2269-7. Epub 2012 Nov 8.

28.

Sodium chloride affects propidium monoazide action to distinguish viable cells.

Barth VC Jr, Cattani F, Ferreira CA, de Oliveira SD.

Anal Biochem. 2012 Sep 15;428(2):108-10. doi: 10.1016/j.ab.2012.06.012. Epub 2012 Jun 20.

PMID:
22728959
29.

Development of LC-MS/MS-based receptor occupancy tracers and positron emission tomography radioligands for the nociceptin/orphanin FQ (NOP) receptor.

Pedregal C, Joshi EM, Toledo MA, Lafuente C, Diaz N, Martinez-Grau MA, Jiménez A, Benito A, Navarro A, Chen Z, Mudra DR, Kahl SD, Rash KS, Statnick MA, Barth VN.

J Med Chem. 2012 Jun 14;55(11):4955-67. doi: 10.1021/jm201629q. Epub 2012 May 16.

PMID:
22541041
30.

3-Phenyl-5-isothiazole carboxamides with potent mGluR1 antagonist activity.

Fisher MJ, Backer RT, Barth VN, Garbison KE, Gruber JM, Heinz BA, Iyengar S, Hollinshead SP, Kingston A, Kuklish SL, Li L, Nisenbaum ES, Peters SC, Phebus L, Simmons RM, van der Aar E.

Bioorg Med Chem Lett. 2012 Apr 1;22(7):2514-7. doi: 10.1016/j.bmcl.2012.02.003. Epub 2012 Feb 9.

PMID:
22386665
31.

Brain and whole-body imaging of nociceptin/orphanin FQ peptide receptor in humans using the PET ligand 11C-NOP-1A.

Lohith TG, Zoghbi SS, Morse CL, Araneta MF, Barth VN, Goebl NA, Tauscher JT, Pike VW, Innis RB, Fujita M.

J Nucl Med. 2012 Mar;53(3):385-92. doi: 10.2967/jnumed.111.097162. Epub 2012 Feb 6.

32.

Discovery of aminobenzyloxyarylamides as κ opioid receptor selective antagonists: application to preclinical development of a κ opioid receptor antagonist receptor occupancy tracer.

Mitch CH, Quimby SJ, Diaz N, Pedregal C, de la Torre MG, Jimenez A, Shi Q, Canada EJ, Kahl SD, Statnick MA, McKinzie DL, Benesh DR, Rash KS, Barth VN.

J Med Chem. 2011 Dec 8;54(23):8000-12. doi: 10.1021/jm200789r. Epub 2011 Oct 26.

PMID:
21958337
33.

Brain and whole-body imaging in rhesus monkeys of 11C-NOP-1A, a promising PET radioligand for nociceptin/orphanin FQ peptide receptors.

Kimura Y, Fujita M, Hong J, Lohith TG, Gladding RL, Zoghbi SS, Tauscher JA, Goebl N, Rash KS, Chen Z, Pedregal C, Barth VN, Pike VW, Innis RB.

J Nucl Med. 2011 Oct;52(10):1638-45. doi: 10.2967/jnumed.111.091181. Epub 2011 Aug 30.

34.

Effectiveness of the proton pump inhibitor omeprazole associated with calcium hydroxide as intracanal medication: an in vivo study.

Wagner C, Barth VC Jr, de Oliveira SD, Campos MM.

J Endod. 2011 Sep;37(9):1253-7. doi: 10.1016/j.joen.2011.06.011. Epub 2011 Jul 20.

PMID:
21846542
35.

Synthesis and evaluation of radioligands for imaging brain nociceptin/orphanin FQ peptide (NOP) receptors with positron emission tomography.

Pike VW, Rash KS, Chen Z, Pedregal C, Statnick MA, Kimura Y, Hong J, Zoghbi SS, Fujita M, Toledo MA, Diaz N, Gackenheimer SL, Tauscher JT, Barth VN, Innis RB.

J Med Chem. 2011 Apr 28;54(8):2687-700. doi: 10.1021/jm101487v. Epub 2011 Mar 25.

36.

Can we add chlorhexidine into glass ionomer cements for band cementation?

Farret MM, de Lima EM, Mota EG, Oshima HM, Barth V, de Oliveira SD.

Angle Orthod. 2011 May;81(3):496-502. doi: 10.2319/090310-518.1. Epub 2011 Feb 7.

PMID:
21299380
37.

In vitro and in vivo evidence for a lack of interaction with dopamine D2 receptors by the metabotropic glutamate 2/3 receptor agonists 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-bicaroxylate monohydrate (LY354740) and (-)-2-oxa-4-aminobicyclo[3.1.0] Hexane-4,6-dicarboxylic acid (LY379268).

Fell MJ, Perry KW, Falcone JF, Johnson BG, Barth VN, Rash KS, Lucaites VL, Threlkeld PG, Monn JA, McKinzie DL, Marek GJ, Svensson KA, Nelson DL.

J Pharmacol Exp Ther. 2009 Dec;331(3):1126-36. doi: 10.1124/jpet.109.160598. Epub 2009 Sep 15.

PMID:
19755662
38.

Comparison of rat dopamine D2 receptor occupancy for a series of antipsychotic drugs measured using radiolabeled or nonlabeled raclopride tracer.

Barth VN, Chernet E, Martin LJ, Need AB, Rash KS, Morin M, Phebus LA.

Life Sci. 2006 May 22;78(26):3007-12. Epub 2006 Jan 24.

PMID:
16434058
39.

Use of LC/MS to assess brain tracer distribution in preclinical, in vivo receptor occupancy studies: dopamine D2, serotonin 2A and NK-1 receptors as examples.

Chernet E, Martin LJ, Li D, Need AB, Barth VN, Rash KS, Phebus LA.

Life Sci. 2005 Dec 12;78(4):340-6. Epub 2005 Sep 1.

PMID:
16139310
40.

Chronic coadministration of olanzapine and fluoxetine activates locus coeruleus neurons in rats: implications for bipolar disorder.

Seager MA, Barth VN, Phebus LA, Rasmussen K.

Psychopharmacology (Berl). 2005 Aug;181(1):126-33. Epub 2005 Oct 15.

PMID:
15719213
41.

Fluoxetine administration potentiates the effect of olanzapine on locus coeruleus neuronal activity.

Seager MA, Huff KD, Barth VN, Phebus LA, Rasmussen K.

Biol Psychiatry. 2004 Jun 1;55(11):1103-9.

PMID:
15158430
42.

Laryngeal morbidity and quality of tracheal intubation: a randomized controlled trial.

Mencke T, Echternach M, Kleinschmidt S, Lux P, Barth V, Plinkert PK, Fuchs-Buder T.

Anesthesiology. 2003 May;98(5):1049-56.

PMID:
12717124
43.

Electropotential measurements as a new diagnostic modality for breast cancer.

Cuzick J, Holland R, Barth V, Davies R, Faupel M, Fentiman I, Frischbier HJ, LaMarque JL, Merson M, Sacchini V, Vanel D, Veronesi U.

Lancet. 1998 Aug 1;352(9125):359-63.

PMID:
9717923
44.

Electropotential evaluation as a new technique for diagnosing breast lesions.

Faupel M, Vanel D, Barth V, Davies R, Fentiman IS, Holland R, Lamarque JL, Sacchini V, Schreer I.

Eur J Radiol. 1997 Jan;24(1):33-8.

PMID:
9056147
45.

Cardiac microembolism: prevalence and clinical outcome.

Eicke BM, Barth V, Kukowski B, Werner G, Paulus W.

J Neurol Sci. 1996 Mar;136(1-2):143-7.

PMID:
8815161
46.

[Effects of chemotherapy and radiotherapy of malignant testicular tumors on residual testicular tissue].

Barth V, Büttner W.

Z Urol Nephrol. 1990 Jul;83(7):367-72. German.

PMID:
2238878
48.

[A rare case of Kaposi sarcoma of the male genitalia].

Barth V, Krauss M, Büttner W.

Z Urol Nephrol. 1990 Mar;83(3):149-51. German. No abstract available.

PMID:
2356669
50.

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