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Items: 1 to 50 of 596

1.

Autophagy role(s) in response to oncogenes and DNA replication stress.

Vanzo R, Bartkova J, Merchut-Maya JM, Hall A, Bouchal J, Dyrskjøt L, Frankel LB, Gorgoulis V, Maya-Mendoza A, Jäättelä M, Bartek J.

Cell Death Differ. 2019 Aug 14. doi: 10.1038/s41418-019-0403-9. [Epub ahead of print]

PMID:
31409894
2.

The Nucleolus: A Multiphase Condensate Balancing Ribosome Synthesis and Translational Capacity in Health, Aging and Ribosomopathies.

Correll CC, Bartek J, Dundr M.

Cells. 2019 Aug 10;8(8). pii: E869. doi: 10.3390/cells8080869. Review.

3.

Disulfiram's anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase.

Skrott Z, Majera D, Gursky J, Buchtova T, Hajduch M, Mistrik M, Bartek J.

Oncogene. 2019 Aug 7. doi: 10.1038/s41388-019-0915-2. [Epub ahead of print]

PMID:
31391554
4.

Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining.

Vougas K, Sakelaropoulos T, Kotsinas A, Foukas GP, Ntargaras A, Koinis F, Polyzos A, Myrianthopoulos V, Zhou H, Narang S, Georgoulias V, Alexopoulos L, Aifantis I, Townsend PA, Sfikakis P, Fitzgerald R, Thanos D, Bartek J, Petty R, Tsirigos A, Gorgoulis VG.

Pharmacol Ther. 2019 Jul 30:107395. doi: 10.1016/j.pharmthera.2019.107395. [Epub ahead of print] Review.

PMID:
31374225
5.

Perturbation of mitochondrial bioenergetics by polycations counteracts resistance to BRAFE600 inhibition in melanoma cells.

Hall A, Maynard S, Wu LP, Merchut-Maya JM, Strauss R, Moghimi SM, Bartek J.

J Control Release. 2019 Jul 23;309:158-172. doi: 10.1016/j.jconrel.2019.07.032. [Epub ahead of print]

PMID:
31348978
6.

Regulation of replication fork speed: Mechanisms and impact on genomic stability.

Merchut-Maya JM, Bartek J, Maya-Mendoza A.

DNA Repair (Amst). 2019 Jul 8:102654. doi: 10.1016/j.dnarep.2019.102654. [Epub ahead of print] Review.

PMID:
31320249
7.

Highly hydrophilic cationic gold nanorods stabilized by novel quaternary ammonium surfactant with negligible cytotoxicity.

Salajkova S, Sramek M, Malinak D, Havel F, Musilek K, Benkova M, Soukup O, Vasicova P, Prchal L, Dolezal R, Hodny Z, Bartek J, Zarska M, Kuca K.

J Biophotonics. 2019 Jul 12:e201900024. doi: 10.1002/jbio.201900024. [Epub ahead of print]

PMID:
31298802
8.

The antimalarial drug amodiaquine stabilizes p53 through ribosome biogenesis stress, independently of its autophagy-inhibitory activity.

Espinoza JA, Zisi A, Kanellis DC, Carreras-Puigvert J, Henriksson M, Hühn D, Watanabe K, Helleday T, Lindström MS, Bartek J.

Cell Death Differ. 2019 Jul 8. doi: 10.1038/s41418-019-0387-5. [Epub ahead of print]

PMID:
31285544
9.

Surgical treatment for symptomatic ventriculus terminalis: case series and a literature review.

Fletcher-Sandersjöö A, Edström E, Bartek J Jr, Elmi-Terander A.

Acta Neurochir (Wien). 2019 Jul 5. doi: 10.1007/s00701-019-03996-0. [Epub ahead of print]

PMID:
31278597
10.

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.

Gogola E, Duarte AA, de Ruiter JR, Wiegant WW, Schmid JA, de Bruijn R, James DI, Llobet SG, Vis DJ, Annunziato S, van den Broek B, Barazas M, Kersbergen A, van de Ven M, Tarsounas M, Ogilvie DJ, van Vugt M, Wessels LFA, Bartkova J, Gromova I, Andújar-Sánchez M, Bartek J, Lopes M, van Attikum H, Borst P, Jonkers J, Rottenberg S.

Cancer Cell. 2019 Jun 10;35(6):950-952. doi: 10.1016/j.ccell.2019.05.012. No abstract available.

11.

Double-strand breaks in ribosomal RNA genes activate a distinct signaling and chromatin response to facilitate nucleolar restructuring and repair.

Korsholm LM, Gál Z, Lin L, Quevedo O, Ahmad DA, Dulina E, Luo Y, Bartek J, Larsen DH.

Nucleic Acids Res. 2019 Jun 11. pii: gkz518. doi: 10.1093/nar/gkz518. [Epub ahead of print]

PMID:
31184714
12.

Serial S100B Sampling Detects Intracranial Lesion Development in Patients on Extracorporeal Membrane Oxygenation.

Fletcher-Sandersjöö A, Lindblad C, Thelin EP, Bartek J Jr, Sallisalmi M, Elmi-Terander A, Svensson M, Bellander BM, Broman LM.

Front Neurol. 2019 May 16;10:512. doi: 10.3389/fneur.2019.00512. eCollection 2019.

13.

Quantification of cellular protein and redox imbalance using SILAC-iodoTMT methodology.

Vajrychova M, Salovska B, Pimkova K, Fabrik I, Tambor V, Kondelova A, Bartek J, Hodny Z.

Redox Biol. 2019 Jun;24:101227. doi: 10.1016/j.redox.2019.101227. Epub 2019 May 21.

14.

Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress.

Young LA, O'Connor LO, de Renty C, Veldman-Jones MH, Dorval T, Wilson Z, Jones DR, Lawson D, Odedra R, Maya-Mendoza A, Reimer C, Bartek J, Lau A, O'Connor MJ.

Cancer Res. 2019 Jul 15;79(14):3762-3775. doi: 10.1158/0008-5472.CAN-18-2480. Epub 2019 May 23.

PMID:
31123088
15.

Laser Ablation of Abnormal Neurological Tissue Using Robotic Neuroblate System (LAANTERN): Procedural Safety and Hospitalization.

Rennert RC, Khan U, Bartek J Jr, Tatter SB, Field M, Toyota B, Fecci PE, Judy K, Mohammadi AM, Landazuri P, Sloan AE, Kim AH, Leuthardt EC, Chen CC.

Neurosurgery. 2019 May 11. pii: nyz141. doi: 10.1093/neuros/nyz141. [Epub ahead of print]

PMID:
31076762
16.

Stereotactic Laser Ablation as Treatment for Brain Metastases Recurring after Stereotactic Radiosurgery: A Systematic Literature Review.

Alattar AA, Bartek J Jr, Chiang VL, Mohammadi AM, Barnett GH, Sloan A, Chen CC.

World Neurosurg. 2019 Apr 30. pii: S1878-8750(19)31195-7. doi: 10.1016/j.wneu.2019.04.200. [Epub ahead of print] Review.

PMID:
31051303
17.

Clinical Course in Chronic Subdural Hematoma Patients Aged 18-49 Compared to Patients 50 Years and Above: A Multicenter Study and Meta-Analysis.

Bartek J Jr, Sjåvik K, Dhawan S, Sagberg LM, Kristiansson H, Ståhl F, Förander P, Chen CC, Jakola AS.

Front Neurol. 2019 Apr 5;10:311. doi: 10.3389/fneur.2019.00311. eCollection 2019.

18.

PML nuclear bodies are recruited to persistent DNA damage lesions in an RNF168-53BP1 dependent manner and contribute to DNA repair.

Vancurova M, Hanzlikova H, Knoblochova L, Kosla J, Majera D, Mistrik M, Burdova K, Hodny Z, Bartek J.

DNA Repair (Amst). 2019 Jun;78:114-127. doi: 10.1016/j.dnarep.2019.04.001. Epub 2019 Apr 6.

PMID:
31009828
19.

Comparison of Frame-Based Versus Frameless Intracranial Stereotactic Biopsy: Systematic Review and Meta-Analysis.

Dhawan S, He Y, Bartek J Jr, Alattar AA, Chen CC.

World Neurosurg. 2019 Jul;127:607-616.e4. doi: 10.1016/j.wneu.2019.04.016. Epub 2019 Apr 8. Review.

PMID:
30974279
20.

Biopsy and Ablation of H3K27 Glioma Using Skull-Mounted Smartframe Device: Technical Case Report.

Bartek J Jr, Alattar A, Jensdottir M, Chen CC.

World Neurosurg. 2019 Jul;127:436-441. doi: 10.1016/j.wneu.2019.04.029. Epub 2019 Apr 9.

PMID:
30974271
21.

Addiction to DUSP1 protects JAK2V617F-driven polycythemia vera progenitors against inflammatory stress and DNA damage, allowing chronic proliferation.

Stetka J, Vyhlidalova P, Lanikova L, Koralkova P, Gursky J, Hlusi A, Flodr P, Hubackova S, Bartek J, Hodny Z, Divoky V.

Oncogene. 2019 Jul;38(28):5627-5642. doi: 10.1038/s41388-019-0813-7. Epub 2019 Apr 9.

PMID:
30967632
22.

Neurosurgical patterns of care for diffuse low-grade gliomas in Sweden between 2005 and 2015.

Carstam L, Smits A, Milos P, Corell A, Henriksson R, Bartek J Jr, Jakola AS.

Neurooncol Pract. 2019 Mar;6(2):124-133. doi: 10.1093/nop/npy023. Epub 2018 Jul 17.

23.

Neurosurgical procedures performed during residency in Europe-preliminary numbers and time trends.

Stienen MN, Bartek J Jr, Czabanka MA, Freyschlag CF, Kolias A, Krieg SM, Moojen W, Renovanz M, Sampron N, Adib SD, Schubert GA, Demetriades AK, Ringel F, Regli L, Schaller K, Meling TR; EANS Young Neurosurgeons and EANS Training Committee.

Acta Neurochir (Wien). 2019 May;161(5):843-853. doi: 10.1007/s00701-019-03888-3. Epub 2019 Mar 29.

PMID:
30927157
24.

Interferon-regulated suprabasin is essential for stress-induced stem-like cell conversion and therapy resistance of human malignancies.

Hubackova S, Pribyl M, Kyjacova L, Moudra A, Dzijak R, Salovska B, Strnad H, Tambor V, Imrichova T, Svec J, Vodicka P, Vaclavikova R, Rob L, Bartek J, Hodny Z.

Mol Oncol. 2019 Jul;13(7):1467-1489. doi: 10.1002/1878-0261.12480. Epub 2019 Jun 10.

25.

Differences in neurosurgical treatment of intracerebral haemorrhage: a nation-wide observational study of 578 consecutive patients.

Fahlström A, Tobieson L, Redebrandt HN, Zeberg H, Bartek J Jr, Bartley A, Erkki M, Hessington A, Troberg E, Mirza S, Tsitsopoulos PP, Marklund N.

Acta Neurochir (Wien). 2019 May;161(5):955-965. doi: 10.1007/s00701-019-03853-0. Epub 2019 Mar 15.

26.

Clinical and histopathological predictors of outcome in malignant meningioma.

Maier AD, Bartek J Jr, Eriksson F, Ugleholdt H, Juhler M, Broholm H, Mathiesen TI.

Neurosurg Rev. 2019 Mar 13. doi: 10.1007/s10143-019-01093-5. [Epub ahead of print]

PMID:
30868425
27.

Short-Term Surgical Outcome for Vestibular Schwannoma in Sweden: A Nation-Wide Registry Study.

Bartek J Jr, Förander P, Thurin E, Wangerid T, Henriksson R, Hesselager G, Jakola AS.

Front Neurol. 2019 Jan 29;10:43. doi: 10.3389/fneur.2019.00043. eCollection 2019.

28.

Neurosurgical treatment and outcome patterns of meningioma in Sweden: a nationwide registry-based study.

Corell A, Thurin E, Skoglund T, Farahmand D, Henriksson R, Rydenhag B, Gulati S, Bartek J Jr, Jakola AS.

Acta Neurochir (Wien). 2019 Feb;161(2):333-341. doi: 10.1007/s00701-019-03799-3. Epub 2019 Jan 24.

29.

Disulfiram repurposing combined with nutritional copper supplement as add-on to chemotherapy in recurrent glioblastoma (DIRECT): Study protocol for a randomized controlled trial.

Jakola AS, Werlenius K, Mudaisi M, Hylin S, Kinhult S, Bartek J Jr, Salvesen Ø, Carlsen SM, Strandéus M, Lindskog M, Löfgren D, Rydenhag B, Carstam L, Gulati S, Solheim O, Bartek J, Solheim T.

F1000Res. 2018 Nov 15;7:1797. doi: 10.12688/f1000research.16786.1. eCollection 2018.

30.

Correction: Identification of neoepitopes recognized by tumor-infiltrating lymphocytes (TILs) from patients with glioma.

Valentini D, Rao M, Meng Q, von Landenberg A, Bartek J Jr, Sinclair G, Paraschoudi G, Jäger E, Harvey-Peredo I, Dodoo E, Maeurer M.

Oncotarget. 2018 Dec 4;9(95):36817. doi: 10.18632/oncotarget.26447. eCollection 2018 Dec 4.

31.

Author Correction: BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity.

Rasmussen RD, Gajjar MK, Tuckova L, Jensen KE, Maya-Mendoza A, Holst CB, Møllgård K, Rasmussen JS, Brennum J, Bartek J Jr, Syrucek M, Sedlakova E, Andersen KK, Frederiksen MH, Bartek J, Hamerlik P.

Nat Commun. 2018 Dec 19;9(1):5396. doi: 10.1038/s41467-018-07892-6.

32.

MYC and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts.

Zhang F, Zakaria SM, Högqvist Tabor V, Singh M, Tronnersjö S, Goodwin J, Selivanova G, Bartek J, Castell A, Larsson LG.

Cell Cycle. 2018;17(24):2697-2715. doi: 10.1080/15384101.2018.1553339. Epub 2018 Dec 17.

33.

Targeting genotoxic and proteotoxic stress-response pathways in human prostate cancer by clinically available PARP inhibitors, vorinostat and disulfiram.

Majera D, Skrott Z, Bouchal J, Bartkova J, Simkova D, Gachechiladze M, Steigerova J, Kurfurstova D, Gursky J, Korinkova G, Cwiertka K, Hodny Z, Mistrik M, Bartek J.

Prostate. 2019 Mar;79(4):352-362. doi: 10.1002/pros.23741. Epub 2018 Nov 29.

PMID:
30499118
34.

Senolytic Cocktail Dasatinib+Quercetin (D+Q) Does Not Enhance the Efficacy of Senescence-Inducing Chemotherapy in Liver Cancer.

Kovacovicova K, Skolnaja M, Heinmaa M, Mistrik M, Pata P, Pata I, Bartek J, Vinciguerra M.

Front Oncol. 2018 Oct 30;8:459. doi: 10.3389/fonc.2018.00459. eCollection 2018.

35.

Stereotactic Brain Biopsy in Eloquent Areas Assisted by Navigated Transcranial Magnetic Stimulation: a Technical Case Report.

Bartek J, Cooray G, Islam M, Jensdottir M.

Oper Neurosurg (Hagerstown). 2019 Sep 1;17(3):E124-E129. doi: 10.1093/ons/opy321.

PMID:
30371829
36.

Challenge of hepatitis C in Egypt and hepatitis B in Mauritania.

Raad II, Chaftari AM, Torres HA, Ayoub EM, Narouz LI, Bartek J, Hachem R.

World J Hepatol. 2018 Sep 27;10(9):549-557. doi: 10.4254/wjh.v10.i9.549. Review.

37.

DNA damage-induced dynamic changes in abundance and cytosol-nuclear translocation of proteins involved in translational processes, metabolism, and autophagy.

Bennetzen MV, Kosar M, Bunkenborg J, Payne MR, Bartkova J, Lindström MS, Lukas J, Andersen JS, Bartek J, Larsen DH.

Cell Cycle. 2018;17(17):2146-2163. doi: 10.1080/15384101.2018.1515552. Epub 2018 Sep 22.

PMID:
30196736
38.

SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability.

Hjorth-Jensen K, Maya-Mendoza A, Dalgaard N, Sigurðsson JO, Bartek J, Iglesias-Gato D, Olsen JV, Flores-Morales A.

Nucleic Acids Res. 2018 Oct 12;46(18):9891. doi: 10.1093/nar/gky788. No abstract available.

39.

Reduced Expression of PROX1 Transitions Glioblastoma Cells into a Mesenchymal Gene Expression Subtype.

Goudarzi KM, Espinoza JA, Guo M, Bartek J, Nistér M, Lindström MS, Hägerstrand D.

Cancer Res. 2018 Oct 15;78(20):5901-5916. doi: 10.1158/0008-5472.CAN-18-0320. Epub 2018 Aug 22.

PMID:
30135192
40.

SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability.

Hjorth-Jensen K, Maya-Mendoza A, Dalgaard N, Sigurðsson JO, Bartek J, Iglesias-Gato D, Olsen JV, Flores-Morales A.

Nucleic Acids Res. 2018 Oct 12;46(18):9484-9495. doi: 10.1093/nar/gky719. Erratum in: Nucleic Acids Res. 2018 Oct 12;46(18):9891.

41.

Incidence, Outcome, and Predictors of Intracranial Hemorrhage in Adult Patients on Extracorporeal Membrane Oxygenation: A Systematic and Narrative Review.

Fletcher-Sandersjöö A, Thelin EP, Bartek J Jr, Broman M, Sallisalmi M, Elmi-Terander A, Bellander BM.

Front Neurol. 2018 Jul 6;9:548. doi: 10.3389/fneur.2018.00548. eCollection 2018. Review.

42.

Phase separated microenvironments inside the cell nucleus are linked to disease and regulate epigenetic state, transcription and RNA processing.

Sawyer IA, Bartek J, Dundr M.

Semin Cell Dev Biol. 2019 Jun;90:94-103. doi: 10.1016/j.semcdb.2018.07.001. Epub 2018 Jul 25. Review.

PMID:
30017905
43.

DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation.

Lemmens B, Hegarat N, Akopyan K, Sala-Gaston J, Bartek J, Hochegger H, Lindqvist A.

Mol Cell. 2018 Jul 5;71(1):117-128.e3. doi: 10.1016/j.molcel.2018.05.026. Epub 2018 Jun 28.

44.

High speed of fork progression induces DNA replication stress and genomic instability.

Maya-Mendoza A, Moudry P, Merchut-Maya JM, Lee M, Strauss R, Bartek J.

Nature. 2018 Jul;559(7713):279-284. doi: 10.1038/s41586-018-0261-5. Epub 2018 Jun 27.

PMID:
29950726
45.

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.

Gogola E, Duarte AA, de Ruiter JR, Wiegant WW, Schmid JA, de Bruijn R, James DI, Guerrero Llobet S, Vis DJ, Annunziato S, van den Broek B, Barazas M, Kersbergen A, van de Ven M, Tarsounas M, Ogilvie DJ, van Vugt M, Wessels LFA, Bartkova J, Gromova I, Andújar-Sánchez M, Bartek J, Lopes M, van Attikum H, Borst P, Jonkers J, Rottenberg S.

Cancer Cell. 2018 Jun 11;33(6):1078-1093.e12. doi: 10.1016/j.ccell.2018.05.008. Erratum in: Cancer Cell. 2019 Jun 10;35(6):950-952.

46.

Amino acid tracers in PET imaging of diffuse low-grade gliomas: a systematic review of preoperative applications.

Näslund O, Smits A, Förander P, Laesser M, Bartek J Jr, Gempt J, Liljegren A, Daxberg EL, Jakola AS.

Acta Neurochir (Wien). 2018 Jul;160(7):1451-1460. doi: 10.1007/s00701-018-3563-3. Epub 2018 May 24.

47.

Scandinavian Multicenter Acute Subdural Hematoma (SMASH) Study: Study Protocol for a Multinational Population-Based Consecutive Cohort.

Bartek J Jr, Laugesen C, Mirza S, Forsse A, Petersen MA, Corell A, Dyhrfort PW, Redebrandt HN, Reen L, Zolfaghari S, Tobieson L, Carlsvärd B, Bergholt B, Bashir A, Soerensen P, Bilgin A, Johansson C, Lindvall P, Förander P, Bellander BM, Springborg JB, Jakola AS.

Neurosurgery. 2019 Mar 1;84(3):799-803. doi: 10.1093/neuros/nyy173. Erratum in: Neurosurgery. 2018 Oct 1;83(4):845.

PMID:
29762769
48.

Identification of neoepitopes recognized by tumor-infiltrating lymphocytes (TILs) from patients with glioma.

Valentini D, Rao M, Meng Q, von Landenberg A, Bartek J Jr, Sinclair G, Paraschoudi G, Jäger E, Harvey-Peredo I, Dodoo E, Maeurer M.

Oncotarget. 2018 Apr 13;9(28):19469-19480. doi: 10.18632/oncotarget.24955. eCollection 2018 Apr 13. Erratum in: Oncotarget. 2018 Dec 4;9(95):36817.

49.

Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence.

Mrazkova B, Dzijak R, Imrichova T, Kyjacova L, Barath P, Dzubak P, Holub D, Hajduch M, Nahacka Z, Andera L, Holicek P, Vasicova P, Sapega O, Bartek J, Hodny Z.

Aging (Albany NY). 2018 Mar 28;10(3):434-462. doi: 10.18632/aging.101404.

50.

Hyperbaric Oxygen Therapy as Adjuvant Treatment for Hardware-Related Infections in Neuromodulation.

Bartek J Jr, Skyrman S, Nekludov M, Mathiesen T, Lind F, Schechtmann G.

Stereotact Funct Neurosurg. 2018;96(2):100-107. doi: 10.1159/000486684. Epub 2018 Apr 3.

PMID:
29614489

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