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Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.

Jackstadt R, van Hooff SR, Leach JD, Cortes-Lavaud X, Lohuis JO, Ridgway RA, Wouters VM, Roper J, Kendall TJ, Roxburgh CS, Horgan PG, Nixon C, Nourse C, Gunzer M, Clark W, Hedley A, Yilmaz OH, Rashid M, Bailey P, Biankin AV, Campbell AD, Adams DJ, Barry ST, Steele CW, Medema JP, Sansom OJ.

Cancer Cell. 2019 Sep 16;36(3):319-336.e7. doi: 10.1016/j.ccell.2019.08.003.


Plasma-Enhanced Atomic Layer Deposition of Nanostructured Gold Near Room Temperature.

Van Daele M, Griffiths MBE, Raza A, Minjauw MM, Solano E, Feng JY, Ramachandran RK, Clemmen S, Baets R, Barry ST, Detavernier C, Dendooven J.

ACS Appl Mater Interfaces. 2019 Oct 9;11(40):37229-37238. doi: 10.1021/acsami.9b10848. Epub 2019 Sep 26.


Experience of and barriers to reporting child safeguarding concerns among general dental practitioners across Greater Manchester.

Clarke L, Chana P, Nazzal H, Barry S.

Br Dent J. 2019 Sep;227(5):387-391. doi: 10.1038/s41415-019-0663-2.


Injecting Gryllus bimaculatus Eggs.

Barry SK, Nakamura T, Matsuoka Y, Straub C, Horch HW, Extavour CG.

J Vis Exp. 2019 Aug 22;(150). doi: 10.3791/59726.


Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer.

Di Mitri D, Mirenda M, Vasilevska J, Calcinotto A, Delaleu N, Revandkar A, Gil V, Boysen G, Losa M, Mosole S, Pasquini E, D'Antuono R, Masetti M, Zagato E, Chiorino G, Ostano P, Rinaldi A, Gnetti L, Graupera M, Martins Figueiredo Fonseca AR, Pereira Mestre R, Waugh D, Barry S, De Bono J, Alimonti A.

Cell Rep. 2019 Aug 20;28(8):2156-2168.e5. doi: 10.1016/j.celrep.2019.07.068.


Private health expenditure in Ireland: Assessing the affordability of private financing of health care.

Johnston BM, Burke S, Barry S, Normand C, Ní Fhallúin M, Thomas S.

Health Policy. 2019 Oct;123(10):963-969. doi: 10.1016/j.healthpol.2019.08.002. Epub 2019 Aug 9.


A cell-engineered system to assess tumor cell sensitivity to CD8+ T cell-mediated cytotoxicity.

Nelson N, Lopez-Pelaez M, Palazon A, Poon E, De La Roche M, Barry S, Valge-Archer V, Wilkinson RW, Dovedi SJ, Smith PD.

Oncoimmunology. 2019 Apr 26;8(8):1599635. doi: 10.1080/2162402X.2019.1599635. eCollection 2019.


Invasive Versus Medical Management in Patients With Prior Coronary Artery Bypass Surgery With a Non-ST Segment Elevation Acute Coronary Syndrome.

Lee MMY, Petrie MC, Rocchiccioli P, Simpson J, Jackson CE, Corcoran DS, Mangion K, Brown A, Cialdella P, Sidik NP, McEntegart MB, Shaukat A, Rae AP, Hood SHM, Peat EE, Findlay IN, Murphy CL, Cormack AJ, Bukov NB, Balachandran KP, Oldroyd KG, Ford I, Wu O, McConnachie A, Barry SJE, Berry C; CABG-ACS Investigators.

Circ Cardiovasc Interv. 2019 Aug;12(8):e007830. doi: 10.1161/CIRCINTERVENTIONS.119.007830. Epub 2019 Jul 31.


The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy.

Reader CS, Vallath S, Steele CW, Haider S, Brentnall A, Desai A, Moore KM, Jamieson NB, Chang D, Bailey P, Scarpa A, Lawlor R, Chelala C, Keyse SM, Biankin A, Morton JP, Evans TJ, Barry ST, Sansom OJ, Kocher HM, Marshall JF.

J Pathol. 2019 Nov;249(3):332-342. doi: 10.1002/path.5320. Epub 2019 Jul 30.


Key Ring Fixator: A Novel External Fixation Technique for Avian Long Bone Stabilization.

Katogiritis A, Barry SL, Finch N.

J Avian Med Surg. 2019 Jun 1;33(2):161-170. doi: 10.1647/2018-355.


Thymus-Derived Regulatory T Cells Exhibit Foxp3 Epigenetic Modification and Phenotype Attenuation after Mating in Mice.

Moldenhauer LM, Schjenken JE, Hope CM, Green ES, Zhang B, Eldi P, Hayball JD, Barry SC, Robertson SA.

J Immunol. 2019 Aug 1;203(3):647-657. doi: 10.4049/jimmunol.1900084. Epub 2019 Jun 26.


Validation of monoclonal anti-PKC isozyme antibodies for flow cytometry analyses in human T cell subsets and expression in cord blood T cells.

Perveen K, Quach A, McPhee A, Prescott SL, Barry SC, Hii CS, Ferrante A.

Sci Rep. 2019 Jun 25;9(1):9263. doi: 10.1038/s41598-019-45507-2.


Medullar Kock without Pott: 13 cases observed at the university hospital center of Conakry, Guinea.

Cisse FA, Sakadi F, Tassiou NRA, Balde AT, Woga ASN, Bah AK, Barry SD, Souare IS, Toure ML, Cisse A.

Iran J Neurol. 2018 Oct 7;17(4):167-173.


Peptidase inhibitor 16 identifies a human regulatory T-cell subset with reduced FOXP3 expression over the first year of recent onset type 1 diabetes.

Hope CM, Welch J, Mohandas A, Pederson S, Hill D, Gundsambuu B, Eastaff-Leung N, Grosse R, Bresatz S, Ang G, Papademetrios M, Zola H, Duhen T, Campbell D, Brown CY, Krumbiegel D, Sadlon T, Couper JJ, Barry SC.

Eur J Immunol. 2019 Aug;49(8):1235-1250. doi: 10.1002/eji.201948094. Epub 2019 Jun 5.


Gut microbiome dysbiosis and increased intestinal permeability in children with islet autoimmunity and type 1 diabetes: A prospective cohort study.

Harbison JE, Roth-Schulze AJ, Giles LC, Tran CD, Ngui KM, Penno MA, Thomson RL, Wentworth JM, Colman PG, Craig ME, Morahan G, Papenfuss AT, Barry SC, Harrison LC, Couper JJ.

Pediatr Diabetes. 2019 Aug;20(5):574-583. doi: 10.1111/pedi.12865. Epub 2019 May 20.


Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation.

Sun D, Stopka-Farooqui U, Barry S, Aksoy E, Parsonage G, Vossenkämper A, Capasso M, Wan X, Norris S, Marshall JL, Clear A, Gribben J, MacDonald TT, Buckley CD, Korbonits M, Haworth O.

Cell Rep. 2019 Apr 30;27(5):1461-1471.e4. doi: 10.1016/j.celrep.2019.04.014.


Orthodontic management of traumatized teeth: A national survey of UK orthodontists.

Sandler C, Barry S, Littlewood S, Al-Musfir T, Nazzal H.

Dent Traumatol. 2019 Oct;35(4-5):241-250. doi: 10.1111/edt.12476. Epub 2019 Jun 28.


Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction.

Schmidleithner L, Thabet Y, Schönfeld E, Köhne M, Sommer D, Abdullah Z, Sadlon T, Osei-Sarpong C, Subbaramaiah K, Copperi F, Haendler K, Varga T, Schanz O, Bourry S, Bassler K, Krebs W, Peters AE, Baumgart AK, Schneeweiss M, Klee K, Schmidt SV, Nüssing S, Sander J, Ohkura N, Waha A, Sparwasser T, Wunderlich FT, Förster I, Ulas T, Weighardt H, Sakaguchi S, Pfeifer A, Blüher M, Dannenberg AJ, Ferreirós N, Muglia LJ, Wickenhauser C, Barry SC, Schultze JL, Beyer M.

Immunity. 2019 May 21;50(5):1232-1248.e14. doi: 10.1016/j.immuni.2019.03.014. Epub 2019 Apr 23.


An internet-delivered cognitive behavioural therapy pain management programme for spinal cord injury pain: A randomized controlled trial.

Burke D, Lennon O, Blake C, Nolan M, Barry S, Smith E, Maye F, Lynch J, O'Connor L, Maume L, Cheyne S, Ní Ghiollain S, Fullen BM.

Eur J Pain. 2019 Aug;23(7):1264-1282. doi: 10.1002/ejp.1402. Epub 2019 Jun 13.


Therapeutic Potential of Regulatory T Cells in Preeclampsia-Opportunities and Challenges.

Robertson SA, Green ES, Care AS, Moldenhauer LM, Prins JR, Hull ML, Barry SC, Dekker G.

Front Immunol. 2019 Mar 21;10:478. doi: 10.3389/fimmu.2019.00478. eCollection 2019. Review.


A discoloured anterior tooth: enamel microabrasion.

Ashfaq NM, Grindrod M, Barry S.

Br Dent J. 2019 Apr;226(7):486-489. doi: 10.1038/s41415-019-0152-7.


Managing polyuria during lithium treatment: a preliminary prospective observational study.

Kinahan JC, Ní Chorcoráin A, Cunningham S, Barry S, Kelly BD.

Ir J Psychol Med. 2019 Apr 10:1-8. doi: 10.1017/ipm.2019.9. [Epub ahead of print]


All systems go: An ecological perspective of behavioral health for youth with type 1 diabetes.

Wagner DV, Koskela-Staples N, Harris MA, Barry SA.

Fam Syst Health. 2019 Mar;37(1):10-29. doi: 10.1037/fsh0000395.


Plantarflexor strength and endurance deficits associated with mid-portion Achilles tendinopathy: The role of soleus.

O'Neill S, Barry S, Watson P.

Phys Ther Sport. 2019 May;37:69-76. doi: 10.1016/j.ptsp.2019.03.002. Epub 2019 Mar 9.


Modeling Dose and Schedule Effects of AZD2811 Nanoparticles Targeting Aurora B Kinase for Treatment of Diffuse Large B-cell Lymphoma.

Floc'h N, Ashton S, Ferguson D, Taylor P, Carnevalli LS, Hughes AM, Harris E, Hattersley M, Wen S, Curtis NJ, Pilling JE, Young LA, Maratea K, Pease EJ, Barry ST.

Mol Cancer Ther. 2019 May;18(5):909-919. doi: 10.1158/1535-7163.MCT-18-0577. Epub 2019 Mar 14.


Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors.

Barry S, Carlsen E, Marques P, Stiles CE, Gadaleta E, Berney DM, Roncaroli F, Chelala C, Solomou A, Herincs M, Caimari F, Grossman AB, Crnogorac-Jurcevic T, Haworth O, Gaston-Massuet C, Korbonits M.

Oncogene. 2019 Jul;38(27):5381-5395. doi: 10.1038/s41388-019-0779-5. Epub 2019 Mar 12.


Canadian neurosurgeons' views on medical assistance in dying (MAID): a cross-sectional survey of Canadian Neurosurgical Society (CNSS) members.

Althagafi A, Ekong C, Wheelock BW, Moulton R, Gorman P, Reddy K, Christie S, Fleetwood I, Barry S.

J Med Ethics. 2019 May;45(5):309-313. doi: 10.1136/medethics-2018-105160. Epub 2019 Mar 12.


Improving Adolescent Depression Screening in Pediatric Primary Care.

Harder VS, Barry SE, French S, Consigli AB, Frankowski BL.

Acad Pediatr. 2019 Mar 9. pii: S1876-2859(18)30529-1. doi: 10.1016/j.acap.2019.02.014. [Epub ahead of print]


Distinct Gut Virome Profile of Pregnant Women With Type 1 Diabetes in the ENDIA Study.

Wook Kim K, Allen DW, Briese T, Couper JJ, Barry SC, Colman PG, Cotterill AM, Davis EA, Giles LC, Harrison LC, Harris M, Haynes A, Horton JL, Isaacs SR, Jain K, Lipkin WI, Morahan G, Morbey C, Pang ICN, Papenfuss AT, Penno MAS, Sinnott RO, Soldatos G, Thomson RL, Vuillermin PJ, Wentworth JM, Wilkins MR, Rawlinson WD, Craig ME; ENDIA Study Group.

Open Forum Infect Dis. 2019 Jan 16;6(2):ofz025. doi: 10.1093/ofid/ofz025. eCollection 2019 Feb.


Swab cloths as a tool for revealing environmental contamination by Q fever in ruminant farms.

Carrié P, Barry S, Rousset E, de Crémoux R, Sala C, Calavas D, Perrin JB, Bronner A, Gasqui P, Gilot-Fromont E, Becker CAM, Gache K, Jourdain E.

Transbound Emerg Dis. 2019 May;66(3):1202-1209. doi: 10.1111/tbed.13137. Epub 2019 Mar 6.


Prehabilitation is feasible in patients with rectal cancer undergoing neoadjuvant chemoradiotherapy and may minimize physical deterioration: results from the REx trial.

Moug SJ, Mutrie N, Barry SJE, Mackay G, Steele RJC, Boachie C, Buchan C, Anderson AS.

Colorectal Dis. 2019 May;21(5):548-562. doi: 10.1111/codi.14560. Epub 2019 Feb 16.


Paediatric type 1 diabetes mellitus: Multidisciplinary approach needed.

Clarke L, Bradshaw T, Pemberton M, Barry S.

Br Dent J. 2019 Jan 11;226(1):3. doi: 10.1038/sj.bdj.2019.16. No abstract available.


Will cost transparency in the operating theatre cause surgeons to change their practice?

Glennie RA, Barry SP, Alant J, Christie S, Oxner WM.

J Clin Neurosci. 2019 Feb;60:1-6. doi: 10.1016/j.jocn.2018.09.024. Epub 2018 Oct 26. Review.


PI3Kα/δ inhibition promotes anti-tumor immunity through direct enhancement of effector CD8+ T-cell activity.

Carnevalli LS, Sinclair C, Taylor MA, Gutierrez PM, Langdon S, Coenen-Stass AML, Mooney L, Hughes A, Jarvis L, Staniszewska A, Crafter C, Sidders B, Hardaker E, Hudson K, Barry ST.

J Immunother Cancer. 2018 Dec 27;6(1):158. doi: 10.1186/s40425-018-0457-0.


The Physical Examination on Admission to the Acute Psychiatric Unit -complete Audit cycle

Elzain M, Elimam I, Barry S.

Ir Med J. 2018 Sep 10;111(8):803.


Peer-led intervention to prevent and reduce STI transmission and improve sexual health in secondary schools (STASH): protocol for a feasibility study.

Forsyth R, Purcell C, Barry S, Simpson S, Hunter R, McDaid L, Elliot L, Bailey J, Wetherall K, McCann M, Broccatelli C, Moore L, Mitchell K.

Pilot Feasibility Stud. 2018 Nov 29;4:180. doi: 10.1186/s40814-018-0354-9. eCollection 2018.


Binding of Distinct Substrate Conformations Enables Hydroxylation of Remote Sites in Thaxtomin D by Cytochrome P450 TxtC.

Alkhalaf LM, Barry SM, Rea D, Gallo A, Griffiths D, Lewandowski JR, Fulop V, Challis GL.

J Am Chem Soc. 2019 Jan 9;141(1):216-222. doi: 10.1021/jacs.8b08864. Epub 2018 Dec 19.


Preclinical Evaluation of AZ12601011 and AZ12799734, Inhibitors of Transforming Growth Factor β Superfamily Type 1 Receptors.

Spender LC, Ferguson GJ, Hughes GD, Davies BR, Goldberg FW, Herrera B, Taylor RG, Strathearn LS, Sansom OJ, Barry ST, Inman GJ.

Mol Pharmacol. 2019 Feb;95(2):222-234. doi: 10.1124/mol.118.112946. Epub 2018 Nov 20.


Retraction notice to "Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury" [Int. J. Cardiol. 163 (2013) 326-334].

Barry SP, Ounzain S, McCormick J, Scarabelli TM, Chen-Scarabelli C, Saravolatz LII, Faggian G, Mazzucco A, Suzuki H, Thiemermann C, Knight RA, Latchman DS, Stephanou A.

Int J Cardiol. 2019 Jan 1;274:404. doi: 10.1016/j.ijcard.2018.10.031. No abstract available.


Infant mutilation: Cultural impact on dental care.

Bibi A, Dixon C, Barry S.

Br Dent J. 2018 Nov 9;225(9):793. doi: 10.1038/sj.bdj.2018.981. No abstract available.


Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival.

Oser MG, Fonseca R, Chakraborty AA, Brough R, Spektor A, Jennings RB, Flaifel A, Novak JS, Gulati A, Buss E, Younger ST, McBrayer SK, Cowley GS, Bonal DM, Nguyen QD, Brulle-Soumare L, Taylor P, Cairo S, Ryan CJ, Pease EJ, Maratea K, Travers J, Root DE, Signoretti S, Pellman D, Ashton S, Lord CJ, Barry ST, Kaelin WG Jr.

Cancer Discov. 2019 Feb;9(2):230-247. doi: 10.1158/2159-8290.CD-18-0389. Epub 2018 Oct 29.


Oral Manifestations of Autoimmune Neutropenia: A Case Report.

Dixon CC, Thomson FJ, Barry SM.

J Clin Pediatr Dent. 2019;43(1):46-50. doi: 10.17796/1053-4625-43.1.9. Epub 2018 Oct 5.


It is a complex issue: emerging connections between epigenetic regulators in drug addiction.

Anderson EM, Penrod RD, Barry SM, Hughes BW, Taniguchi M, Cowan CW.

Eur J Neurosci. 2019 Aug;50(3):2477-2491. doi: 10.1111/ejn.14170. Epub 2018 Oct 10. Review.


Regulation of biosimilar medicines and current perspectives on interchangeability and policy.

O'Callaghan J, Barry SP, Bermingham M, Morris JM, Griffin BT.

Eur J Clin Pharmacol. 2019 Jan;75(1):1-11. doi: 10.1007/s00228-018-2542-1. Epub 2018 Sep 5. Review.


Divergent Prelimbic Cortical Pathways Interact with BDNF to Regulate Cocaine-seeking.

Giannotti G, Barry SM, Siemsen BM, Peters J, McGinty JF.

J Neurosci. 2018 Oct 17;38(42):8956-8966. doi: 10.1523/JNEUROSCI.1332-18.2018. Epub 2018 Sep 5.


TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence.

Bird TG, Müller M, Boulter L, Vincent DF, Ridgway RA, Lopez-Guadamillas E, Lu WY, Jamieson T, Govaere O, Campbell AD, Ferreira-Gonzalez S, Cole AM, Hay T, Simpson KJ, Clark W, Hedley A, Clarke M, Gentaz P, Nixon C, Bryce S, Kiourtis C, Sprangers J, Nibbs RJB, Van Rooijen N, Bartholin L, McGreal SR, Apte U, Barry ST, Iredale JP, Clarke AR, Serrano M, Roskams TA, Sansom OJ, Forbes SJ.

Sci Transl Med. 2018 Aug 15;10(454). pii: eaan1230. doi: 10.1126/scitranslmed.aan1230.


Combined Inhibition of PI3Kβ and mTOR Inhibits Growth of PTEN-null Tumors.

Lynch JT, Polanska UM, Hancox U, Delpuech O, Maynard J, Trigwell C, Eberlein C, Lenaghan C, Polanski R, Avivar-Valderas A, Cumberbatch M, Klinowska T, Critchlow SE, Cruzalegui F, Barry ST.

Mol Cancer Ther. 2018 Nov;17(11):2309-2319. doi: 10.1158/1535-7163.MCT-18-0183. Epub 2018 Aug 10.


Long-term weight loss following a randomised controlled trial of a weight management programme for men delivered through professional football clubs: the Football Fans in Training follow-up study.

Gray CM, Wyke S, Zhang R, Anderson AS, Barry S, Brennan G, Briggs A, Boyer N, Bunn C, Donnachie C, Grieve E, Kohli-Lynch C, Lloyd S, McConnachie A, McCowan C, McLean A, Mutrie N, Hunt K.

Southampton (UK): NIHR Journals Library; 2018 Jul.


Hypophosphatasia and the importance of the general dental practitioner - a case series and discussion of upcoming treatments.

Feeney C, Stanford N, Lee S, Barry S.

Br Dent J. 2018 Jun 22;224(12):937-943. doi: 10.1038/sj.bdj.2018.441.


FOXP3 and miR-155 cooperate to control the invasive potential of human breast cancer cells by down regulating ZEB2 independently of ZEB1.

Brown CY, Dayan S, Wong SW, Kaczmarek A, Hope CM, Pederson SM, Arnet V, Goodall GJ, Russell D, Sadlon TJ, Barry SC.

Oncotarget. 2018 Jun 12;9(45):27708-27727. doi: 10.18632/oncotarget.25523. eCollection 2018 Jun 12.

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