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Items: 1 to 50 of 237

1.

Longer TOMM40 poly-T variants associated with higher FDDNP-PET medial temporal tau and amyloid binding.

Siddarth P, Burggren AC, Merrill DA, Ercoli LM, Mahmood Z, Barrio JR, Small GW.

PLoS One. 2018 Dec 5;13(12):e0208358. doi: 10.1371/journal.pone.0208358. eCollection 2018.

2.

Sodium-glucose transporter 2 is a diagnostic and therapeutic target for early-stage lung adenocarcinoma.

Scafoglio CR, Villegas B, Abdelhady G, Bailey ST, Liu J, Shirali AS, Wallace WD, Magyar CE, Grogan TR, Elashoff D, Walser T, Yanagawa J, Aberle DR, Barrio JR, Dubinett SM, Shackelford DB.

Sci Transl Med. 2018 Nov 14;10(467). pii: eaat5933. doi: 10.1126/scitranslmed.aat5933.

3.

FDDNP-PET Tau Brain Protein Binding Patterns in Military Personnel with Suspected Chronic Traumatic Encephalopathy1.

Chen ST, Siddarth P, Merrill DA, Martinez J, Emerson ND, Liu J, Wong KP, Satyamurthy N, Giza CC, Huang SC, Fitzsimmons RP, Bailes J, Omalu B, Barrio JR, Small GW.

J Alzheimers Dis. 2018;65(1):79-88. doi: 10.3233/JAD-171152.

4.

The Value of In Vitro Binding as Predictor of In Vivo Results: A Case for [18F]FDDNP PET.

Cole GB, Satyamurthy N, Liu J, Wong KP, Small GW, Huang SC, Košmrlj J, Barrio JR, Petrič A.

Mol Imaging Biol. 2019 Feb;21(1):25-34. doi: 10.1007/s11307-018-1210-2.

PMID:
29855843
5.

Intestinal absorption of glucose in mice as determined by positron emission tomography.

Sala-Rabanal M, Ghezzi C, Hirayama BA, Kepe V, Liu J, Barrio JR, Wright EM.

J Physiol. 2018 Jul;596(13):2473-2489. doi: 10.1113/JP275934. Epub 2018 Jun 5.

6.

Response to Letter About Memory and Brain Effects of Curcumin.

Siddarth P, Barrio JR, Small GW.

Am J Geriatr Psychiatry. 2018 Jun;26(6):716-717. doi: 10.1016/j.jagp.2018.03.014. Epub 2018 Mar 29. No abstract available.

7.

Positron emission tomography of sodium glucose cotransport activity in high grade astrocytomas.

Kepe V, Scafoglio C, Liu J, Yong WH, Bergsneider M, Huang SC, Barrio JR, Wright EM.

J Neurooncol. 2018 Jul;138(3):557-569. doi: 10.1007/s11060-018-2823-7. Epub 2018 Mar 10.

8.

Circular Inference in Dementia Diagnostics.

Høilund-Carlsen PF, Barrio JR, Gjedde A, Werner TJ, Alavi A.

J Alzheimers Dis. 2018;63(1):69-73. doi: 10.3233/JAD-180050.

PMID:
29504544
9.

Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial.

Small GW, Siddarth P, Li Z, Miller KJ, Ercoli L, Emerson ND, Martinez J, Wong KP, Liu J, Merrill DA, Chen ST, Henning SM, Satyamurthy N, Huang SC, Heber D, Barrio JR.

Am J Geriatr Psychiatry. 2018 Mar;26(3):266-277. doi: 10.1016/j.jagp.2017.10.010. Epub 2017 Oct 27.

10.

Postmortem Autopsy-Confirmation of Antemortem [F-18]FDDNP-PET Scans in a Football Player With Chronic Traumatic Encephalopathy.

Omalu B, Small GW, Bailes J, Ercoli LM, Merrill DA, Wong KP, Huang SC, Satyamurthy N, Hammers JL, Lee J, Fitzsimmons RP, Barrio JR.

Neurosurgery. 2018 Feb 1;82(2):237-246. doi: 10.1093/neuros/nyx536.

11.

The Irony of PET Tau Probe Specificity.

Barrio JR.

J Nucl Med. 2018 Jan;59(1):115-116. doi: 10.2967/jnumed.117.198960. Epub 2017 Nov 9. No abstract available.

12.

In Vivo Brain Plaque and Tangle Burden Mediates the Association Between Diastolic Blood Pressure and Cognitive Functioning in Nondemented Adults.

Roussotte FF, Siddarth P, Merrill DA, Narr KL, Ercoli LM, Martinez J, Emerson ND, Barrio JR, Small GW.

Am J Geriatr Psychiatry. 2018 Jan;26(1):13-22. doi: 10.1016/j.jagp.2017.09.001. Epub 2017 Sep 15.

13.

Design, Syntheses, and in Vitro Evaluation of New Fluorine-18 Radiolabeled Tau-Labeling Molecular Probes.

Rejc L, Šmid L, Kepe V, Podlipnik Č, Golobič A, Bresjanac M, Barrio JR, Petrič A, Košmrlj J.

J Med Chem. 2017 Nov 9;60(21):8741-8757. doi: 10.1021/acs.jmedchem.7b00764. Epub 2017 Oct 2.

PMID:
28921979
14.

Neural correlates of apathy in late-life depression: a pilot [18 F]FDDNP positron emission tomography study.

Eyre HA, Siddarth P, van Dyk K, St Cyr N, Baune BT, Barrio JR, Small GW, Lavretsky H.

Psychogeriatrics. 2017 May;17(3):186-193. doi: 10.1111/psyg.12213. Epub 2017 Jan 28.

15.

Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer's Disease: The Role of APP.

Doran E, Keator D, Head E, Phelan MJ, Kim R, Totoiu M, Barrio JR, Small GW, Potkin SG, Lott IT.

J Alzheimers Dis. 2017;56(2):459-470. doi: 10.3233/JAD-160836.

16.

Cross-Sectional and Longitudinal Cognitive Correlates of FDDNP PET and CSF Amyloid-β and Tau in Parkinson's Disease1.

Buongiorno M, Antonelli F, Compta Y, Fernandez Y, Pavia J, Lomeña F, Ríos J, Ramírez I, García JR, Soler M, Cámara A, Fernández M, Basora M, Salazar F, Sanchez-Etayo G, Valldeoriola F, Barrio JR, Marti MJ.

J Alzheimers Dis. 2017;55(3):1261-1272.

PMID:
27814297
17.

A semi-automated workflow solution for multimodal neuroimaging: application to patients with traumatic brain injury.

Wong KP, Bergsneider M, Glenn TC, Kepe V, Barrio JR, Hovda DA, Vespa PM, Huang SC.

Brain Inform. 2016 Mar;3(1):1-15. Epub 2015 Dec 1.

18.

Dapagliflozin Binds Specifically to Sodium-Glucose Cotransporter 2 in the Proximal Renal Tubule.

Ghezzi C, Yu AS, Hirayama BA, Kepe V, Liu J, Scafoglio C, Powell DR, Huang SC, Satyamurthy N, Barrio JR, Wright EM.

J Am Soc Nephrol. 2017 Mar;28(3):802-810. doi: 10.1681/ASN.2016050510. Epub 2016 Sep 12.

19.

Progressive Focal Gray Matter Volume Loss in a Former High School Football Player: A Possible Magnetic Resonance Imaging Volumetric Signature for Chronic Traumatic Encephalopathy.

Raji CA, Merrill DA, Barrio JR, Omalu B, Small GW.

Am J Geriatr Psychiatry. 2016 Oct;24(10):784-90. doi: 10.1016/j.jagp.2016.07.018. Epub 2016 Jul 28.

20.

Modifiable Risk Factors and Brain Positron Emission Tomography Measures of Amyloid and Tau in Nondemented Adults with Memory Complaints.

Merrill DA, Siddarth P, Raji CA, Emerson ND, Rueda F, Ercoli LM, Miller KJ, Lavretsky H, Harris LM, Burggren AC, Bookheimer SY, Barrio JR, Small GW.

Am J Geriatr Psychiatry. 2016 Sep;24(9):729-37. doi: 10.1016/j.jagp.2016.05.007. Epub 2016 May 13.

21.

A semi-automated workflow solution for multimodal neuroimaging: application to patients with traumatic brain injury.

Wong KP, Bergsneider M, Glenn TC, Kepe V, Barrio JR, Hovda DA, Vespa PM, Huang SC.

Brain Inform. 2016;3:1-15. Epub 2015 Dec 1.

22.

Revisiting the physiological roles of SGLTs and GLUTs using positron emission tomography in mice.

Sala-Rabanal M, Hirayama BA, Ghezzi C, Liu J, Huang SC, Kepe V, Koepsell H, Yu A, Powell DR, Thorens B, Wright EM, Barrio JR.

J Physiol. 2016 Aug 1;594(15):4425-38. doi: 10.1113/JP271904. Epub 2016 May 10.

23.

Functional expression of sodium-glucose transporters in cancer.

Scafoglio C, Hirayama BA, Kepe V, Liu J, Ghezzi C, Satyamurthy N, Moatamed NA, Huang J, Koepsell H, Barrio JR, Wright EM.

Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):E4111-9. doi: 10.1073/pnas.1511698112. Epub 2015 Jul 13.

24.

In vivo characterization of chronic traumatic encephalopathy using [F-18]FDDNP PET brain imaging.

Barrio JR, Small GW, Wong KP, Huang SC, Liu J, Merrill DA, Giza CC, Fitzsimmons RP, Omalu B, Bailes J, Kepe V.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E2039-47. doi: 10.1073/pnas.1409952112. Epub 2015 Apr 6. Erratum in: Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):E2981.

25.

Automated movement correction for dynamic PET/CT images: evaluation with phantom and patient data.

Ye H, Wong KP, Wardak M, Dahlbom M, Kepe V, Barrio JR, Nelson LD, Small GW, Huang SC.

PLoS One. 2014 Aug 11;9(8):e103745. doi: 10.1371/journal.pone.0103745. eCollection 2014.

26.

Cerebral amyloid PET imaging in Alzheimer's disease.

Jack CR Jr, Barrio JR, Kepe V.

Acta Neuropathol. 2013 Nov;126(5):643-57. doi: 10.1007/s00401-013-1185-7. Epub 2013 Oct 8. Review.

27.

High-pressure, compact, modular radiosynthesizer for production of positron emitting biomarkers.

Amaraesekera B, Marchis PD, Bobinski KP, Radu CG, Czernin J, Barrio JR, Michael van Dam R.

Appl Radiat Isot. 2013 Aug;78:88-101. doi: 10.1016/j.apradiso.2013.04.024. Epub 2013 Apr 25.

PMID:
23702794
28.

Amyloid-β positron emission tomography imaging probes: a critical review.

Kepe V, Moghbel MC, Långström B, Zaidi H, Vinters HV, Huang SC, Satyamurthy N, Doudet D, Mishani E, Cohen RM, Høilund-Carlsen PF, Alavi A, Barrio JR.

J Alzheimers Dis. 2013;36(4):613-31. doi: 10.3233/JAD-130485. Review.

29.

PET imaging of neuropathology in tauopathies: progressive supranuclear palsy.

Kepe V, Bordelon Y, Boxer A, Huang SC, Liu J, Thiede FC, Mazziotta JC, Mendez MF, Donoghue N, Small GW, Barrio JR.

J Alzheimers Dis. 2013;36(1):145-53. doi: 10.3233/JAD-130032.

30.

A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss.

Cohen RM, Rezai-Zadeh K, Weitz TM, Rentsendorj A, Gate D, Spivak I, Bholat Y, Vasilevko V, Glabe CG, Breunig JJ, Rakic P, Davtyan H, Agadjanyan MG, Kepe V, Barrio JR, Bannykh S, Szekely CA, Pechnick RN, Town T.

J Neurosci. 2013 Apr 10;33(15):6245-56. doi: 10.1523/JNEUROSCI.3672-12.2013.

31.

Postmortem 3-D brain hemisphere cortical tau and amyloid-β pathology mapping and quantification as a validation method of neuropathology imaging.

Smid LM, Kepe V, Vinters HV, Bresjanac M, Toyokuni T, Satyamurthy N, Wong KP, Huang SC, Silverman DH, Miller K, Small GW, Barrio JR.

J Alzheimers Dis. 2013;36(2):261-74. doi: 10.3233/JAD-122434.

32.

Psychological well-being and regional brain amyloid and tau in mild cognitive impairment.

Chen ST, Siddarth P, Saito NY, Rueda F, Haight T, Ercoli LM, Miller KJ, Lavretsky H, Barrio JR, Bookheimer SY, Small GW, Merrill DA.

Am J Geriatr Psychiatry. 2014 Apr;22(4):362-9. doi: 10.1016/j.jagp.2012.09.002. Epub 2013 Mar 26.

33.

Vascular risk and FDDNP-PET influence cognitive performance.

Merrill DA, Siddarth P, Kepe V, Raja PV, Saito N, Ercoli LM, Miller KJ, Lavretsky H, Bookheimer SY, Barrio JR, Small GW.

J Alzheimers Dis. 2013;35(1):147-57. doi: 10.3233/JAD-121903.

34.

PET scanning of brain tau in retired national football league players: preliminary findings.

Small GW, Kepe V, Siddarth P, Ercoli LM, Merrill DA, Donoghue N, Bookheimer SY, Martinez J, Omalu B, Bailes J, Barrio JR.

Am J Geriatr Psychiatry. 2013 Feb;21(2):138-44. doi: 10.1016/j.jagp.2012.11.019. Epub 2013 Jan 22.

PMID:
23343487
35.

Regional distribution of SGLT activity in rat brain in vivo.

Yu AS, Hirayama BA, Timbol G, Liu J, Diez-Sampedro A, Kepe V, Satyamurthy N, Huang SC, Wright EM, Barrio JR.

Am J Physiol Cell Physiol. 2013 Feb 1;304(3):C240-7. doi: 10.1152/ajpcell.00317.2012. Epub 2012 Nov 14.

36.

Dicyanovinylnaphthalenes for neuroimaging of amyloids and relationships of electronic structures and geometries to binding affinities.

Petric A, Johnson SA, Pham HV, Li Y, Ceh S, Golobic A, Agdeppa ED, Timbol G, Liu J, Keum G, Satyamurthy N, Kepe V, Houk KN, Barrio JR.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16492-7. doi: 10.1073/pnas.1214134109. Epub 2012 Sep 25. Erratum in: Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5269.

37.

Procedures for Preparation and Radiolabeling of a 3-Fluoropyrrolidine-Containing FDDNP Analog.

Fister A, Barrio JR, Petrič A.

Acta Chim Slov. 2012 Jun;59(2):431-5.

PMID:
24061263
38.

Automated VOI Analysis in FDDNP PET Using Structural Warping: Validation through Classification of Alzheimer's Disease Patients.

Wilks MQ, Protas H, Wardak M, Kepe V, Small GW, Barrio JR, Huang SC.

Int J Alzheimers Dis. 2012;2012:512069. doi: 10.1155/2012/512069. Epub 2012 Mar 1.

39.

Prediction of cognitive decline based on hemispheric cortical surface maps of FDDNP PET.

Protas HD, Kepe V, Hayashi KM, Klunder AD, Braskie MN, Ercoli L, Siddarth P, Bookheimer SY, Thompson PM, Small GW, Barrio JR, Huang SC.

Neuroimage. 2012 Jul 16;61(4):749-60. doi: 10.1016/j.neuroimage.2012.02.056. Epub 2012 Feb 28.

40.

Assessment of dementia risk in aging adults using both FDG-PET and FDDNP-PET imaging.

Ercoli LM, Small GW, Siddarth P, Kepe V, Huang SC, Miller KJ, Lavretsky H, Bookheimer SY, Barrio JR, Silverman DH.

Int J Geriatr Psychiatry. 2012 Oct;27(10):1017-27. doi: 10.1002/gps.2816. Epub 2012 Mar 1.

41.

Self-reported memory impairment and brain PET of amyloid and tau in middle-aged and older adults without dementia.

Merrill DA, Siddarth P, Saito NY, Ercoli LM, Burggren AC, Kepe V, Lavretsky H, Miller KJ, Kim J, Huang SC, Bookheimer SY, Barrio JR, Small GW.

Int Psychogeriatr. 2012 Jul;24(7):1076-84. doi: 10.1017/S1041610212000051. Epub 2012 Feb 16.

42.

Prediction of cognitive decline by positron emission tomography of brain amyloid and tau.

Small GW, Siddarth P, Kepe V, Ercoli LM, Burggren AC, Bookheimer SY, Miller KJ, Kim J, Lavretsky H, Huang SC, Barrio JR.

Arch Neurol. 2012 Feb;69(2):215-22. doi: 10.1001/archneurol.2011.559.

43.

Comparative evaluation of Logan and relative-equilibrium graphical methods for parametric imaging of dynamic [18F]FDDNP PET determinations.

Wong KP, Kepe V, Dahlbom M, Satyamurthy N, Small GW, Barrio JR, Huang SC.

Neuroimage. 2012 Mar;60(1):241-51. doi: 10.1016/j.neuroimage.2011.12.014. Epub 2011 Dec 16.

44.

Protein binding in patients with late-life depression.

Kumar A, Kepe V, Barrio JR, Siddarth P, Manoukian V, Elderkin-Thompson V, Small GW.

Arch Gen Psychiatry. 2011 Nov;68(11):1143-50. doi: 10.1001/archgenpsychiatry.2011.122.

45.

The merits of FDDNP-PET imaging in Alzheimer's disease.

Shin J, Kepe V, Barrio JR, Small GW.

J Alzheimers Dis. 2011;26 Suppl 3:135-45. doi: 10.3233/JAD-2011-0008. Review.

PMID:
21971458
46.

Structural selectivity of human SGLT inhibitors.

Hummel CS, Lu C, Liu J, Ghezzi C, Hirayama BA, Loo DD, Kepe V, Barrio JR, Wright EM.

Am J Physiol Cell Physiol. 2012 Jan 15;302(2):C373-82. doi: 10.1152/ajpcell.00328.2011. Epub 2011 Sep 21.

47.

Towards a pharmacophore for amyloid.

Landau M, Sawaya MR, Faull KF, Laganowsky A, Jiang L, Sievers SA, Liu J, Barrio JR, Eisenberg D.

PLoS Biol. 2011 Jun;9(6):e1001080. doi: 10.1371/journal.pbio.1001080. Epub 2011 Jun 14.

48.

Positron emission tomography of brain β-amyloid and τ levels in adults with Down syndrome.

Nelson LD, Siddarth P, Kepe V, Scheibel KE, Huang SC, Barrio JR, Small GW.

Arch Neurol. 2011 Jun;68(6):768-74. doi: 10.1001/archneurol.2011.104.

49.

Multimodal Imaging of Alzheimer Pathophysiology in the Brain's Default Mode Network.

Shin J, Kepe V, Small GW, Phelps ME, Barrio JR.

Int J Alzheimers Dis. 2011;2011:687945. doi: 10.4061/2011/687945. Epub 2011 Apr 19.

50.

[F-18]FDDNP microPET imaging correlates with brain Aβ burden in a transgenic rat model of Alzheimer disease: effects of aging, in vivo blockade, and anti-Aβ antibody treatment.

Teng E, Kepe V, Frautschy SA, Liu J, Satyamurthy N, Yang F, Chen PP, Cole GB, Jones MR, Huang SC, Flood DG, Trusko SP, Small GW, Cole GM, Barrio JR.

Neurobiol Dis. 2011 Sep;43(3):565-75. doi: 10.1016/j.nbd.2011.05.003. Epub 2011 May 13.

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