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Items: 1 to 50 of 76

1.

Genetic and evolutionary determinants of human population variation in immune responses.

Sanz J, Randolph HE, Barreiro LB.

Curr Opin Genet Dev. 2018 Jun 28;53:28-35. doi: 10.1016/j.gde.2018.06.009. [Epub ahead of print] Review.

PMID:
29960896
2.

Holy Immune Tolerance, Batman!

Randolph HE, Barreiro LB.

Immunity. 2018 Jun 19;48(6):1074-1076. doi: 10.1016/j.immuni.2018.05.016.

PMID:
29924972
3.

Vaginal microbiome in early pregnancy and subsequent risk of spontaneous preterm birth: a case-control study.

Tabatabaei N, Eren AM, Barreiro LB, Yotova V, Dumaine A, Allard C, Fraser WD.

BJOG. 2018 May 23. doi: 10.1111/1471-0528.15299. [Epub ahead of print]

PMID:
29791775
4.

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

Meisel M, Hinterleitner R, Pacis A, Chen L, Earley ZM, Mayassi T, Pierre JF, Ernest JD, Galipeau HJ, Thuille N, Bouziat R, Buscarlet M, Ringus DL, Wang Y, Li Y, Dinh V, Kim SM, McDonald BD, Zurenski MA, Musch MW, Furtado GC, Lira SA, Baier G, Chang EB, Eren AM, Weber CR, Busque L, Godley LA, Verdú EF, Barreiro LB, Jabri B.

Nature. 2018 May;557(7706):580-584. doi: 10.1038/s41586-018-0125-z. Epub 2018 May 16.

PMID:
29769727
5.

The demographic history and mutational load of African hunter-gatherers and farmers.

Lopez M, Kousathanas A, Quach H, Harmant C, Mouguiama-Daouda P, Hombert JM, Froment A, Perry GH, Barreiro LB, Verdu P, Patin E, Quintana-Murci L.

Nat Ecol Evol. 2018 Apr;2(4):721-730. doi: 10.1038/s41559-018-0496-4. Epub 2018 Mar 12.

PMID:
29531345
6.

BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis.

Kaufmann E, Sanz J, Dunn JL, Khan N, Mendonça LE, Pacis A, Tzelepis F, Pernet E, Dumaine A, Grenier JC, Mailhot-Léonard F, Ahmed E, Belle J, Besla R, Mazer B, King IL, Nijnik A, Robbins CS, Barreiro LB, Divangahi M.

Cell. 2018 Jan 11;172(1-2):176-190.e19. doi: 10.1016/j.cell.2017.12.031.

PMID:
29328912
7.

The contribution of admixture to primate evolution.

Tung J, Barreiro LB.

Curr Opin Genet Dev. 2017 Dec;47:61-68. doi: 10.1016/j.gde.2017.08.010. Epub 2017 Sep 15. Review.

PMID:
28923540
8.

α7 nicotinic acetylcholine receptor signaling modulates the inflammatory phenotype of fetal brain microglia: first evidence of interference by iron homeostasis.

Cortes M, Cao M, Liu HL, Moore CS, Durosier LD, Burns P, Fecteau G, Desrochers A, Barreiro LB, Antel JP, Frasch MG.

Sci Rep. 2017 Sep 6;7(1):10645. doi: 10.1038/s41598-017-09439-z.

9.

Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations.

Kim-Hellmuth S, Bechheim M, Pütz B, Mohammadi P, Nédélec Y, Giangreco N, Becker J, Kaiser V, Fricker N, Beier E, Boor P, Castel SE, Nöthen MM, Barreiro LB, Pickrell JK, Müller-Myhsok B, Lappalainen T, Schumacher J, Hornung V.

Nat Commun. 2017 Aug 16;8(1):266. doi: 10.1038/s41467-017-00366-1.

10.

Deciphering the genetic control of gene expression following Mycobacterium leprae antigen stimulation.

Manry J, Nédélec Y, Fava VM, Cobat A, Orlova M, Thuc NV, Thai VH, Laval G, Barreiro LB, Schurr E.

PLoS Genet. 2017 Aug 9;13(8):e1006952. doi: 10.1371/journal.pgen.1006952. eCollection 2017 Aug.

11.

Predicting susceptibility to tuberculosis based on gene expression profiling in dendritic cells.

Blischak JD, Tailleux L, Myrthil M, Charlois C, Bergot E, Dinh A, Morizot G, Chény O, Platen CV, Herrmann JL, Brosch R, Barreiro LB, Gilad Y.

Sci Rep. 2017 Jul 18;7(1):5702. doi: 10.1038/s41598-017-05878-w.

12.

Gene-body 5-hydroxymethylation is associated with gene expression changes in the prefrontal cortex of depressed individuals.

Gross JA, Pacis A, Chen GG, Drupals M, Lutz PE, Barreiro LB, Turecki G.

Transl Psychiatry. 2017 May 9;7(5):e1119. doi: 10.1038/tp.2017.93.

13.

Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America.

Patin E, Lopez M, Grollemund R, Verdu P, Harmant C, Quach H, Laval G, Perry GH, Barreiro LB, Froment A, Heyer E, Massougbodji A, Fortes-Lima C, Migot-Nabias F, Bellis G, Dugoujon JM, Pereira JB, Fernandes V, Pereira L, Van der Veen L, Mouguiama-Daouda P, Bustamante CD, Hombert JM, Quintana-Murci L.

Science. 2017 May 5;356(6337):543-546. doi: 10.1126/science.aal1988.

PMID:
28473590
14.

Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease.

Bouziat R, Hinterleitner R, Brown JJ, Stencel-Baerenwald JE, Ikizler M, Mayassi T, Meisel M, Kim SM, Discepolo V, Pruijssers AJ, Ernest JD, Iskarpatyoti JA, Costes LM, Lawrence I, Palanski BA, Varma M, Zurenski MA, Khomandiak S, McAllister N, Aravamudhan P, Boehme KW, Hu F, Samsom JN, Reinecker HC, Kupfer SS, Guandalini S, Semrad CE, Abadie V, Khosla C, Barreiro LB, Xavier RJ, Ng A, Dermody TS, Jabri B.

Science. 2017 Apr 7;356(6333):44-50. doi: 10.1126/science.aah5298.

15.

Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans.

Sams AJ, Dumaine A, Nédélec Y, Yotova V, Alfieri C, Tanner JE, Messer PW, Barreiro LB.

Genome Biol. 2016 Nov 29;17(1):246.

16.

Social status alters immune regulation and response to infection in macaques.

Snyder-Mackler N, Sanz J, Kohn JN, Brinkworth JF, Morrow S, Shaver AO, Grenier JC, Pique-Regi R, Johnson ZP, Wilson ME, Barreiro LB, Tung J.

Science. 2016 Nov 25;354(6315):1041-1045.

17.

RNAseq profiling of primary microglia and astrocyte cultures in near-term ovine fetus: A glial in vivo-in vitro multi-hit paradigm in large mammalian brain.

Cortes M, Cao M, Liu HL, Burns P, Moore C, Fecteau G, Desrochers A, Barreiro LB, Antel JP, Frasch MG.

J Neurosci Methods. 2017 Jan 30;276:23-32. doi: 10.1016/j.jneumeth.2016.11.008. Epub 2016 Nov 14.

18.

Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens.

Nédélec Y, Sanz J, Baharian G, Szpiech ZA, Pacis A, Dumaine A, Grenier JC, Freiman A, Sams AJ, Hebert S, Pagé Sabourin A, Luca F, Blekhman R, Hernandez RD, Pique-Regi R, Tung J, Yotova V, Barreiro LB.

Cell. 2016 Oct 20;167(3):657-669.e21. doi: 10.1016/j.cell.2016.09.025.

19.

Genetic and transcriptional analysis of human host response to healthy gut microbiota.

Richards AL, Burns MB, Alazizi A, Barreiro LB, Pique-Regi R, Blekhman R, Luca F.

mSystems. 2016 Jul-Aug;1(4). pii: e00067-16. Epub 2016 Aug 30.

20.

Widespread Shortening of 3' Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection.

Pai AA, Baharian G, Pagé Sabourin A, Brinkworth JF, Nédélec Y, Foley JW, Grenier JC, Siddle KJ, Dumaine A, Yotova V, Johnson ZP, Lanford RE, Burge CB, Barreiro LB.

PLoS Genet. 2016 Sep 30;12(9):e1006338. doi: 10.1371/journal.pgen.1006338. eCollection 2016 Sep.

21.

Dominance rank causally affects personality and glucocorticoid regulation in female rhesus macaques.

Kohn JN, Snyder-Mackler N, Barreiro LB, Johnson ZP, Tung J, Wilson ME.

Psychoneuroendocrinology. 2016 Dec;74:179-188. doi: 10.1016/j.psyneuen.2016.09.005. Epub 2016 Sep 12.

22.

Alu repeats as transcriptional regulatory platforms in macrophage responses to M. tuberculosis infection.

Bouttier M, Laperriere D, Memari B, Mangiapane J, Fiore A, Mitchell E, Verway M, Behr MA, Sladek R, Barreiro LB, Mader S, White JH.

Nucleic Acids Res. 2016 Dec 15;44(22):10571-10587. Epub 2016 Sep 6.

23.

Common methods for fecal sample storage in field studies yield consistent signatures of individual identity in microbiome sequencing data.

Blekhman R, Tang K, Archie EA, Barreiro LB, Johnson ZP, Wilson ME, Kohn J, Yuan ML, Gesquiere L, Grieneisen LE, Tung J.

Sci Rep. 2016 Aug 16;6:31519. doi: 10.1038/srep31519.

24.

The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation.

Langlais D, Barreiro LB, Gros P.

J Exp Med. 2016 Apr 4;213(4):585-603. doi: 10.1084/jem.20151764. Epub 2016 Mar 21.

25.

Social status drives social relationships in groups of unrelated female rhesus macaques.

Snyder-Mackler N, Kohn JN, Barreiro LB, Johnson ZP, Wilson ME, Tung J.

Anim Behav. 2016 Jan 1;111:307-317.

26.

The epigenomic landscape of African rainforest hunter-gatherers and farmers.

Fagny M, Patin E, MacIsaac JL, Rotival M, Flutre T, Jones MJ, Siddle KJ, Quach H, Harmant C, McEwen LM, Froment A, Heyer E, Gessain A, Betsem E, Mouguiama-Daouda P, Hombert JM, Perry GH, Barreiro LB, Kobor MS, Quintana-Murci L.

Nat Commun. 2015 Nov 30;6:10047. doi: 10.1038/ncomms10047.

27.

Mycobacterial infection induces a specific human innate immune response.

Blischak JD, Tailleux L, Mitrano A, Barreiro LB, Gilad Y.

Sci Rep. 2015 Nov 20;5:16882. doi: 10.1038/srep16882.

28.

Genome-Wide Association Studies of the Human Gut Microbiota.

Davenport ER, Cusanovich DA, Michelini K, Barreiro LB, Ober C, Gilad Y.

PLoS One. 2015 Nov 3;10(11):e0140301. doi: 10.1371/journal.pone.0140301. eCollection 2015.

29.

Bacterial infection remodels the DNA methylation landscape of human dendritic cells.

Pacis A, Tailleux L, Morin AM, Lambourne J, MacIsaac JL, Yotova V, Dumaine A, Danckaert A, Luca F, Grenier JC, Hansen KD, Gicquel B, Yu M, Pai A, He C, Tung J, Pastinen T, Kobor MS, Pique-Regi R, Gilad Y, Barreiro LB.

Genome Res. 2015 Dec;25(12):1801-11. doi: 10.1101/gr.192005.115. Epub 2015 Sep 21.

30.

Characterizing 5-hydroxymethylcytosine in human prefrontal cortex at single base resolution.

Gross JA, Pacis A, Chen GG, Barreiro LB, Ernst C, Turecki G.

BMC Genomics. 2015 Sep 3;16:672. doi: 10.1186/s12864-015-1875-8.

31.

Fetal microglial phenotype in vitro carries memory of prior in vivo exposure to inflammation.

Cao M, Cortes M, Moore CS, Leong SY, Durosier LD, Burns P, Fecteau G, Desrochers A, Auer RN, Barreiro LB, Antel JP, Frasch MG.

Front Cell Neurosci. 2015 Aug 4;9:294. doi: 10.3389/fncel.2015.00294. eCollection 2015.

32.

bacterial infection drives the expression dynamics of microRNAs and their isomiRs.

Siddle KJ, Tailleux L, Deschamps M, Loh YH, Deluen C, Gicquel B, Antoniewski C, Barreiro LB, Farinelli L, Quintana-Murci L.

PLoS Genet. 2015 Mar 20;11(3):e1005064. doi: 10.1371/journal.pgen.1005064. eCollection 2015 Mar. Erratum in: PLoS Genet. 2015 Jun;11(6):e1005321.

33.

Social networks predict gut microbiome composition in wild baboons.

Tung J, Barreiro LB, Burns MB, Grenier JC, Lynch J, Grieneisen LE, Altmann J, Alberts SC, Blekhman R, Archie EA.

Elife. 2015 Mar 16;4. doi: 10.7554/eLife.05224.

34.

Annexin1 regulates DC efferocytosis and cross-presentation during Mycobacterium tuberculosis infection.

Tzelepis F, Verway M, Daoud J, Gillard J, Hassani-Ardakani K, Dunn J, Downey J, Gentile ME, Jaworska J, Sanchez AM, Nédélec Y, Vali H, Tabrizian M, Kristof AS, King IL, Barreiro LB, Divangahi M.

J Clin Invest. 2015 Feb;125(2):752-68. doi: 10.1172/JCI77014. Epub 2014 Dec 22.

35.

Reservoir host immune responses to emerging zoonotic viruses.

Mandl JN, Ahmed R, Barreiro LB, Daszak P, Epstein JH, Virgin HW, Feinberg MB.

Cell. 2015 Jan 15;160(1-2):20-35. doi: 10.1016/j.cell.2014.12.003. Epub 2014 Dec 18. Review.

36.

The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease.

Brinkworth JF, Barreiro LB.

Curr Opin Immunol. 2014 Dec;31:66-78. doi: 10.1016/j.coi.2014.09.008. Epub 2014 Oct 22. Review.

37.

Editorial Overview: immunogenetics and transplantation: bringing evolution and genomics to human immunology.

Barreiro LB, Quintana-Murci L.

Curr Opin Immunol. 2014 Oct;30:v-vii. doi: 10.1016/j.coi.2014.09.003. Epub 2014 Sep 17. No abstract available.

PMID:
25240536
38.

Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers.

Perry GH, Foll M, Grenier JC, Patin E, Nédélec Y, Pacis A, Barakatt M, Gravel S, Zhou X, Nsobya SL, Excoffier L, Quintana-Murci L, Dominy NJ, Barreiro LB.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3596-603. doi: 10.1073/pnas.1402875111. Epub 2014 Aug 18.

39.

When genetics meets epigenetics: deciphering the mechanisms controlling inter-individual variation in immune responses to infection.

Pacis A, Nédélec Y, Barreiro LB.

Curr Opin Immunol. 2014 Aug;29:119-26. doi: 10.1016/j.coi.2014.06.002. Epub 2014 Jun 28. Review.

PMID:
24981784
40.

Human NKG2E is expressed and forms an intracytoplasmic complex with CD94 and DAP12.

Orbelyan GA, Tang F, Sally B, Solus J, Meresse B, Ciszewski C, Grenier JC, Barreiro LB, Lanier LL, Jabri B.

J Immunol. 2014 Jul 15;193(2):610-6. doi: 10.4049/jimmunol.1400556. Epub 2014 Jun 16.

41.

Quantitative trait loci (QTL) study identifies novel genomic regions associated to Chiari-like malformation in Griffon Bruxellois dogs.

Lemay P, Knowler SP, Bouasker S, Nédélec Y, Platt S, Freeman C, Child G, Barreiro LB, Rouleau GA, Rusbridge C, Kibar Z.

PLoS One. 2014 Apr 16;9(4):e89816. doi: 10.1371/journal.pone.0089816. eCollection 2014.

42.

Exploring the occurrence of classic selective sweeps in humans using whole-genome sequencing data sets.

Fagny M, Patin E, Enard D, Barreiro LB, Quintana-Murci L, Laval G.

Mol Biol Evol. 2014 Jul;31(7):1850-68. doi: 10.1093/molbev/msu118. Epub 2014 Apr 1.

PMID:
24694833
43.

Seasonal variation in human gut microbiome composition.

Davenport ER, Mizrahi-Man O, Michelini K, Barreiro LB, Ober C, Gilad Y.

PLoS One. 2014 Mar 11;9(3):e90731. doi: 10.1371/journal.pone.0090731. eCollection 2014.

44.

Extracellular adenosine triphosphate affects the response of human macrophages infected with Mycobacterium tuberculosis.

Dubois-Colas N, Petit-Jentreau L, Barreiro LB, Durand S, Soubigou G, Lecointe C, Klibi J, Rezaï K, Lokiec F, Coppée JY, Gicquel B, Tailleux L.

J Infect Dis. 2014 Sep 1;210(5):824-33. doi: 10.1093/infdis/jiu135. Epub 2014 Mar 5.

PMID:
24604822
45.

The impact of agricultural emergence on the genetic history of African rainforest hunter-gatherers and agriculturalists.

Patin E, Siddle KJ, Laval G, Quach H, Harmant C, Becker N, Froment A, Régnault B, Lemée L, Gravel S, Hombert JM, Van der Veen L, Dominy NJ, Perry GH, Barreiro LB, Verdu P, Heyer E, Quintana-Murci L.

Nat Commun. 2014;5:3163. doi: 10.1038/ncomms4163.

PMID:
24495941
46.

A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection.

Siddle KJ, Deschamps M, Tailleux L, Nédélec Y, Pothlichet J, Lugo-Villarino G, Libri V, Gicquel B, Neyrolles O, Laval G, Patin E, Barreiro LB, Quintana-Murci L.

Genome Res. 2014 May;24(5):850-9. doi: 10.1101/gr.161471.113. Epub 2014 Jan 30.

47.

Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations.

Quach H, Wilson D, Laval G, Patin E, Manry J, Guibert J, Barreiro LB, Nerrienet E, Verschoor E, Gessain A, Przeworski M, Quintana-Murci L.

Hum Mol Genet. 2013 Dec 1;22(23):4829-40. doi: 10.1093/hmg/ddt335. Epub 2013 Jul 12.

48.

Age-dependent association between pulmonary tuberculosis and common TOX variants in the 8q12-13 linkage region.

Grant AV, El Baghdadi J, Sabri A, El Azbaoui S, Alaoui-Tahiri K, Abderrahmani Rhorfi I, Gharbaoui Y, Abid A, Benkirane M, Raharimanga V, Richard V, Orlova M, Boland A, Migaud M, Okada S, Nolan DK, Bustamante J, Barreiro LB, Schurr E, Boisson-Dupuis S, Rasolofo V, Casanova JL, Abel L.

Am J Hum Genet. 2013 Mar 7;92(3):407-14. doi: 10.1016/j.ajhg.2013.01.013. Epub 2013 Feb 14.

49.
50.

Social environment is associated with gene regulatory variation in the rhesus macaque immune system.

Tung J, Barreiro LB, Johnson ZP, Hansen KD, Michopoulos V, Toufexis D, Michelini K, Wilson ME, Gilad Y.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6490-5. doi: 10.1073/pnas.1202734109. Epub 2012 Apr 9.

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