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Items: 40

1.

A phase I window, dose escalating and safety trial of metformin in combination with induction chemotherapy in relapsed refractory acute lymphoblastic leukemia: Metformin with induction chemotherapy of vincristine, dexamethasone, PEG-asparaginase, and doxorubicin.

Trucco M, Barredo JC, Goldberg J, Leclerc GM, Hale GA, Gill J, Setty B, Smith T, Lush R, Lee JK, Reed DR.

Pediatr Blood Cancer. 2018 Jun 1:e27224. doi: 10.1002/pbc.27224. [Epub ahead of print]

PMID:
29856514
2.

Inhibition of the NEDD8 conjugation pathway induces calcium-dependent compensatory activation of the pro-survival MEK/ERK pathway in acute lymphoblastic leukemia.

Zheng S, Leclerc GM, Li B, Swords RT, Barredo JC.

Oncotarget. 2017 Dec 31;9(5):5529-5544. doi: 10.18632/oncotarget.23797. eCollection 2018 Jan 19.

3.

Isolated late testicular relapse of B-cell acute lymphoblastic leukemia treated with intensive systemic chemotherapy and response-based testicular radiation: A Children's Oncology Group study.

Barredo JC, Hastings C, Lu X, Devidas M, Chen Y, Armstrong D, Winick N, Wood BL, Yanofsky R, Loh M, Gastier-Foster JM, Jorstad DT, Marcus R, Ritchey K, Carrol WL, Hunger SP.

Pediatr Blood Cancer. 2018 May;65(5):e26928. doi: 10.1002/pbc.26928. Epub 2017 Dec 29.

PMID:
29286562
4.

Adenoid cystic carcinoma of the lacrimal gland in a 14-year-old male.

Falcone MM, Tran KD, Tavakoli M, Ortiz DF, Barredo JC, Lee WW.

Orbit. 2017 Dec;36(6):448-451. doi: 10.1080/01676830.2017.1337187. Epub 2017 Jul 24.

PMID:
28738175
5.

The NEDD8-activating enzyme inhibitor pevonedistat activates the eIF2α and mTOR pathways inducing UPR-mediated cell death in acute lymphoblastic leukemia.

Leclerc GM, Zheng S, Leclerc GJ, DeSalvo J, Swords RT, Barredo JC.

Leuk Res. 2016 Nov;50:1-10. doi: 10.1016/j.leukres.2016.09.007. Epub 2016 Sep 5.

PMID:
27626202
6.

Primary Mediastinal Large B-Cell Lymphoma With Translocations Involving BCL6 and MYC (Double-Hit Lymphoma).

Campuzano-Zuluaga G, Ortiz D, Peng JH, Francis Ikpatt O, Fan YS, Barredo JC, Vega F, Chapman JR.

Am J Clin Pathol. 2016 May;145(5):710-6. doi: 10.1093/ajcp/aqw018. Epub 2016 Mar 27.

PMID:
27124935
7.

Mcl-1 downregulation leads to the heightened sensitivity exhibited by BCR-ABL positive ALL to induction of energy and ER-stress.

Leclerc GJ, DeSalvo J, Du J, Gao N, Leclerc GM, Lehrman MA, Lampidis TJ, Barredo JC.

Leuk Res. 2015 Aug 20. pii: S0145-2126(15)30360-X. doi: 10.1016/j.leukres.2015.08.007. [Epub ahead of print]

8.

Metformin induces apoptosis through AMPK-dependent inhibition of UPR signaling in ALL lymphoblasts.

Leclerc GM, Leclerc GJ, Kuznetsov JN, DeSalvo J, Barredo JC.

PLoS One. 2013 Aug 23;8(8):e74420. doi: 10.1371/journal.pone.0074420. eCollection 2013.

9.

Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKβ leading to autophagy.

Xi H, Barredo JC, Merchan JR, Lampidis TJ.

Biochem Pharmacol. 2013 May 15;85(10):1463-77. doi: 10.1016/j.bcp.2013.02.037. Epub 2013 Mar 13.

PMID:
23500541
10.

Inhibition of Akt potentiates 2-DG-induced apoptosis via downregulation of UPR in acute lymphoblastic leukemia.

DeSalvo J, Kuznetsov JN, Du J, Leclerc GM, Leclerc GJ, Lampidis TJ, Barredo JC.

Mol Cancer Res. 2012 Jul;10(7):969-78. doi: 10.1158/1541-7786.MCR-12-0125. Epub 2012 Jun 12.

11.

Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG).

Wang WC, Ware RE, Miller ST, Iyer RV, Casella JF, Minniti CP, Rana S, Thornburg CD, Rogers ZR, Kalpatthi RV, Barredo JC, Brown RC, Sarnaik SA, Howard TH, Wynn LW, Kutlar A, Armstrong FD, Files BA, Goldsmith JC, Waclawiw MA, Huang X, Thompson BW; BABY HUG investigators.

Lancet. 2011 May 14;377(9778):1663-72. doi: 10.1016/S0140-6736(11)60355-3.

12.

AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia.

Kuznetsov JN, Leclerc GJ, Leclerc GM, Barredo JC.

Mol Cancer Ther. 2011 Mar;10(3):437-47. doi: 10.1158/1535-7163.MCT-10-0777. Epub 2011 Jan 24.

13.

AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia.

Leclerc GM, Leclerc GJ, Fu G, Barredo JC.

J Mol Signal. 2010 Sep 23;5:15. doi: 10.1186/1750-2187-5-15.

14.

Folylpolyglutamate synthetase gene transcription is regulated by a multiprotein complex that binds the TEL-AML1 fusion in acute lymphoblastic leukemia.

Leclerc GJ, Sanderson C, Hunger S, Devidas M, Barredo JC.

Leuk Res. 2010 Dec;34(12):1601-9. doi: 10.1016/j.leukres.2010.05.012. Epub 2010 Jun 9.

15.
16.

Simultaneous presentation of retinoblastoma and morning glory disk anomaly.

Wykoff CC, Dubovy SR, Barredo JC, Murray TG.

Retin Cases Brief Rep. 2009 Fall;3(4):354-7. doi: 10.1097/ICB.0b013e318177fa39.

PMID:
25389845
17.

The pediatric hydroxyurea phase III clinical trial (BABY HUG): challenges of study design.

Thompson BW, Miller ST, Rogers ZR, Rees RC, Ware RE, Waclawiw MA, Iyer RV, Casella JF, Luchtman-Jones L, Rana S, Thornburg CD, Kalpatthi RV, Barredo JC, Brown RC, Sarnaik S, Howard TH, Luck L, Wang WC.

Pediatr Blood Cancer. 2010 Feb;54(2):250-5. doi: 10.1002/pbc.22269.

18.

Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury.

Adamkiewicz TV, Abboud MR, Paley C, Olivieri N, Kirby-Allen M, Vichinsky E, Casella JF, Alvarez OA, Barredo JC, Lee MT, Iyer RV, Kutlar A, McKie KM, McKie V, Odo N, Gee B, Kwiatkowski JL, Woods GM, Coates T, Wang W, Adams RJ.

Blood. 2009 Nov 19;114(21):4632-8. doi: 10.1182/blood-2009-02-203323. Epub 2009 Aug 31.

19.

Successful use of fondaparinux as an alternative anticoagulant in a 2-month-old infant.

Mason AR, McBurney PG, Fuller MP, Barredo JC, Lazarchick J.

Pediatr Blood Cancer. 2008 May;50(5):1084-5. doi: 10.1002/pbc.21445. No abstract available.

PMID:
18213695
20.

Outcomes after HLA-matched sibling transplantation or chemotherapy in children with acute lymphoblastic leukemia in a second remission after an isolated central nervous system relapse: a collaborative study of the Children's Oncology Group and the Center for International Blood and Marrow Transplant Research.

Eapen M, Zhang MJ, Devidas M, Raetz E, Barredo JC, Ritchey AK, Godder K, Grupp S, Lewis VA, Malloy K, Carroll WL, Davies SM, Camitta BM; Children's Oncology Group; Center for International Blood and Marrow Transplant Research.

Leukemia. 2008 Feb;22(2):281-6. Epub 2007 Nov 22.

PMID:
18033318
21.
22.

Molecular basis for decreased folylpoly-gamma-glutamate synthetase expression in a methotrexate resistant CCRF-CEM mutant cell line.

Leclerc GJ, York TA, Hsieh-Kinser T, Barredo JC.

Leuk Res. 2007 Mar;31(3):293-9. Epub 2006 Aug 1.

PMID:
16884772
23.

Isolated CNS relapse of acute lymphoblastic leukemia treated with intensive systemic chemotherapy and delayed CNS radiation: a pediatric oncology group study.

Barredo JC, Devidas M, Lauer SJ, Billett A, Marymont M, Pullen J, Camitta B, Winick N, Carroll W, Ritchey AK.

J Clin Oncol. 2006 Jul 1;24(19):3142-9.

PMID:
16809737
24.
25.

Pediatric rhabdomyosarcoma of the head and neck.

Gillespie MB, Marshall DT, Day TA, Mitchell AO, White DR, Barredo JC.

Curr Treat Options Oncol. 2006 Jan;7(1):13-22. Review.

PMID:
16343365
26.
28.

Assessment of barriers to bone marrow donation by unrelated African-American potential donors.

Laver JH, Hulsey TC, Jones JP, Gautreaux M, Barredo JC, Abboud MR.

Biol Blood Marrow Transplant. 2001;7(1):45-8.

29.

Effects of cranial radiation in children with high risk T cell acute lymphoblastic leukemia: a Pediatric Oncology Group report.

Laver JH, Barredo JC, Amylon M, Schwenn M, Kurtzberg J, Camitta BM, Pullen J, Link MP, Borowitz M, Ravindranath Y, Murphy SB, Shuster J.

Leukemia. 2000 Mar;14(3):369-73.

PMID:
10720128
30.
31.

Postdural puncture headache in paediatric oncology patients.

Burt N, Dorman BH, Reeves ST, Rust PF, Pinosky ML, Abboud MR, Barredo JC, Laver JH.

Can J Anaesth. 1998 Aug;45(8):741-5.

PMID:
9793663
32.

Survival with combined modality therapy after intracerebral recurrence of pleuropulmonary blastoma.

Yusuf U, Dufour D, Jenrette JM 3rd, Abboud MR, Laver J, Barredo JC.

Med Pediatr Oncol. 1998 Jan;30(1):63-6.

PMID:
9371392
33.

Successful treatment of relapsed infant acute lymphoblastic leukemia with intensive antimetabolite-based chemotherapy.

Barredo JC, Yusuf U, Abboud M, Laver J.

Med Pediatr Oncol. 1997 Oct;29(4):256-9.

PMID:
9251730
34.

All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders.

Rowley JD, Reshmi S, Sobulo O, Musvee T, Anastasi J, Raimondi S, Schneider NR, Barredo JC, Cantu ES, Schlegelberger B, Behm F, Doggett NA, Borrow J, Zeleznik-Le N.

Blood. 1997 Jul 15;90(2):535-41.

35.
36.

Transient therapy-related myelodysplastic syndrome associated with monosomy 7 and 11q23 translocation.

Laver JH, Yusuf U, Cantu ES, Barredo JC, Holt LB, Abboud MR.

Leukemia. 1997 Mar;11(3):448-50.

PMID:
9067588
37.

Progressive autologous graft-versus-host disease induced by cyclosporin A.

Barredo JC, Yusuf U, Hahn A, Abboud MR, Laver J.

Bone Marrow Transplant. 1996 Sep;18(3):659-62.

PMID:
8879637
38.

Role of folylpolygutamate synthetase (FPGS) in antifolate chemotherapy; a biochemical and clinical update.

Synold TW, Willits EM, Barredo JC.

Leuk Lymphoma. 1996 Mar;21(1-2):9-15. Review.

PMID:
8907263
39.

Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia.

Barredo JC, Synold TW, Laver J, Relling MV, Pui CH, Priest DG, Evans WE.

Blood. 1994 Jul 15;84(2):564-9.

40.

Effects of radiation and 4-hydroperoxycyclophosphamide on production of G- and GM-CSF by stromal cells.

Laver JH, Xu F, Barredo JC, Abboud MR.

Bone Marrow Transplant. 1992 Dec;10(6):529-33.

PMID:
1283360

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