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Items: 34

1.

Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade.

Rashidian M, LaFleur MW, Verschoor VL, Dongre A, Zhang Y, Nguyen TH, Kolifrath S, Aref AR, Lau CJ, Paweletz CP, Bu X, Freeman GJ, Barrasa MI, Weinberg RA, Sharpe AH, Ploegh HL.

Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16971-16980. doi: 10.1073/pnas.1905005116. Epub 2019 Aug 2.

PMID:
31375632
2.

Rate of Progression through a Continuum of Transit-Amplifying Progenitor Cell States Regulates Blood Cell Production.

Li H, Natarajan A, Ezike J, Barrasa MI, Le Y, Feder ZA, Yang H, Ma C, Markoulaki S, Lodish HF.

Dev Cell. 2019 Apr 8;49(1):118-129.e7. doi: 10.1016/j.devcel.2019.01.026. Epub 2019 Feb 28.

PMID:
30827895
3.

Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment.

Fanning S, Haque A, Imberdis T, Baru V, Barrasa MI, Nuber S, Termine D, Ramalingam N, Ho GPH, Noble T, Sandoe J, Lou Y, Landgraf D, Freyzon Y, Newby G, Soldner F, Terry-Kantor E, Kim TE, Hofbauer HF, Becuwe M, Jaenisch R, Pincus D, Clish CB, Walther TC, Farese RV Jr, Srinivasan S, Welte MA, Kohlwein SD, Dettmer U, Lindquist S, Selkoe D.

Mol Cell. 2019 Mar 7;73(5):1001-1014.e8. doi: 10.1016/j.molcel.2018.11.028. Epub 2018 Dec 4.

PMID:
30527540
4.

New CRISPR Mutagenesis Strategies Reveal Variation in Repair Mechanisms among Fungi.

Vyas VK, Bushkin GG, Bernstein DA, Getz MA, Sewastianik M, Barrasa MI, Bartel DP, Fink GR.

mSphere. 2018 Apr 25;3(2). pii: e00154-18. doi: 10.1128/mSphere.00154-18. Print 2018 Apr 25.

5.

Translocon Declogger Ste24 Protects against IAPP Oligomer-Induced Proteotoxicity.

Kayatekin C, Amasino A, Gaglia G, Flannick J, Bonner JM, Fanning S, Narayan P, Barrasa MI, Pincus D, Landgraf D, Nelson J, Hesse WR, Costanzo M; AMP T2D-GENES Consortium, Myers CL, Boone C, Florez JC, Lindquist S.

Cell. 2018 Mar 22;173(1):62-73.e9. doi: 10.1016/j.cell.2018.02.026. Epub 2018 Mar 8.

6.

Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation.

Gao X, Lee HY, Li W, Platt RJ, Barrasa MI, Ma Q, Elmes RR, Rosenfeld MG, Lodish HF.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10107-10112. doi: 10.1073/pnas.1711058114. Epub 2017 Sep 1.

7.

Dihydropyrimidine-Thiones and Clioquinol Synergize To Target β-Amyloid Cellular Pathologies through a Metal-Dependent Mechanism.

Tardiff DF, Brown LE, Yan X, Trilles R, Jui NT, Barrasa MI, Caldwell KA, Caldwell GA, Schaus SE, Lindquist S.

ACS Chem Neurosci. 2017 Sep 20;8(9):2039-2055. doi: 10.1021/acschemneuro.7b00187. Epub 2017 Jul 12.

8.

Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways.

Khurana V, Peng J, Chung CY, Auluck PK, Fanning S, Tardiff DF, Bartels T, Koeva M, Eichhorn SW, Benyamini H, Lou Y, Nutter-Upham A, Baru V, Freyzon Y, Tuncbag N, Costanzo M, San Luis BJ, Schöndorf DC, Barrasa MI, Ehsani S, Sanjana N, Zhong Q, Gasser T, Bartel DP, Vidal M, Deleidi M, Boone C, Fraenkel E, Berger B, Lindquist S.

Cell Syst. 2017 Feb 22;4(2):157-170.e14. doi: 10.1016/j.cels.2016.12.011. Epub 2017 Jan 25.

9.

TGF-β inhibitors stimulate red blood cell production by enhancing self-renewal of BFU-E erythroid progenitors.

Gao X, Lee HY, da Rocha EL, Zhang C, Lu YF, Li D, Feng Y, Ezike J, Elmes RR, Barrasa MI, Cahan P, Li H, Daley GQ, Lodish HF.

Blood. 2016 Dec 8;128(23):2637-2641. Epub 2016 Oct 24.

10.

Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression.

Soldner F, Stelzer Y, Shivalila CS, Abraham BJ, Latourelle JC, Barrasa MI, Goldmann J, Myers RH, Young RA, Jaenisch R.

Nature. 2016 May 5;533(7601):95-9. doi: 10.1038/nature17939. Epub 2016 Apr 20.

11.

Replication fork progression during re-replication requires the DNA damage checkpoint and double-strand break repair.

Alexander JL, Barrasa MI, Orr-Weaver TL.

Curr Biol. 2015 Jun 15;25(12):1654-60. doi: 10.1016/j.cub.2015.04.058. Epub 2015 Jun 4.

12.
13.

PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal.

Lee HY, Gao X, Barrasa MI, Li H, Elmes RR, Peters LL, Lodish HF.

Nature. 2015 Jun 25;522(7557):474-7. doi: 10.1038/nature14326. Epub 2015 May 11.

14.

Loss of Tet enzymes compromises proper differentiation of embryonic stem cells.

Dawlaty MM, Breiling A, Le T, Barrasa MI, Raddatz G, Gao Q, Powell BE, Cheng AW, Faull KF, Lyko F, Jaenisch R.

Dev Cell. 2014 Apr 14;29(1):102-11. doi: 10.1016/j.devcel.2014.03.003.

15.

Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.

Dawlaty MM, Breiling A, Le T, Raddatz G, Barrasa MI, Cheng AW, Gao Q, Powell BE, Li Z, Xu M, Faull KF, Lyko F, Jaenisch R.

Dev Cell. 2013 Feb 11;24(3):310-23. doi: 10.1016/j.devcel.2012.12.015. Epub 2013 Jan 24.

16.

Sortase-mediated modification of αDEC205 affords optimization of antigen presentation and immunization against a set of viral epitopes.

Swee LK, Guimaraes CP, Sehrawat S, Spooner E, Barrasa MI, Ploegh HL.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1428-33. doi: 10.1073/pnas.1214994110. Epub 2013 Jan 7.

17.

Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia.

Sanda T, Lawton LN, Barrasa MI, Fan ZP, Kohlhammer H, Gutierrez A, Ma W, Tatarek J, Ahn Y, Kelliher MA, Jamieson CH, Staudt LM, Young RA, Look AT.

Cancer Cell. 2012 Aug 14;22(2):209-21. doi: 10.1016/j.ccr.2012.06.007.

18.

Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression.

Gao Q, Steine EJ, Barrasa MI, Hockemeyer D, Pawlak M, Fu D, Reddy S, Bell GW, Jaenisch R.

Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18061-6. doi: 10.1073/pnas.1114946108. Epub 2011 Oct 19.

19.

Chromosome-biased binding and gene regulation by the Caenorhabditis elegans DRM complex.

Tabuchi TM, Deplancke B, Osato N, Zhu LJ, Barrasa MI, Harrison MM, Horvitz HR, Walhout AJ, Hagstrom KA.

PLoS Genet. 2011 May;7(5):e1002074. doi: 10.1371/journal.pgen.1002074. Epub 2011 May 12.

20.

A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors.

Grove CA, De Masi F, Barrasa MI, Newburger DE, Alkema MJ, Bulyk ML, Walhout AJ.

Cell. 2009 Jul 23;138(2):314-27. doi: 10.1016/j.cell.2009.04.058.

21.

The C. elegans Snail homolog CES-1 can activate gene expression in vivo and share targets with bHLH transcription factors.

Reece-Hoyes JS, Deplancke B, Barrasa MI, Hatzold J, Smit RB, Arda HE, Pope PA, Gaudet J, Conradt B, Walhout AJ.

Nucleic Acids Res. 2009 Jun;37(11):3689-98. doi: 10.1093/nar/gkp232. Epub 2009 Apr 16.

22.

Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity.

Martinez NJ, Ow MC, Reece-Hoyes JS, Barrasa MI, Ambros VR, Walhout AJ.

Genome Res. 2008 Dec;18(12):2005-15. doi: 10.1101/gr.083055.108. Epub 2008 Nov 3.

23.

A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity.

Martinez NJ, Ow MC, Barrasa MI, Hammell M, Sequerra R, Doucette-Stamm L, Roth FP, Ambros VR, Walhout AJ.

Genes Dev. 2008 Sep 15;22(18):2535-49. doi: 10.1101/gad.1678608.

24.

The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans.

Ow MC, Martinez NJ, Olsen PH, Silverman HS, Barrasa MI, Conradt B, Walhout AJ, Ambros V.

Genes Dev. 2008 Sep 15;22(18):2520-34. doi: 10.1101/gad.1678808.

25.

Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping.

Vermeirssen V, Deplancke B, Barrasa MI, Reece-Hoyes JS, Arda HE, Grove CA, Martinez NJ, Sequerra R, Doucette-Stamm L, Brent MR, Walhout AJ.

Nat Methods. 2007 Aug;4(8):659-64. Epub 2007 Jun 24.

PMID:
17589517
26.

Transcription factor modularity in a gene-centered C. elegans core neuronal protein-DNA interaction network.

Vermeirssen V, Barrasa MI, Hidalgo CA, Babon JA, Sequerra R, Doucette-Stamm L, Barabási AL, Walhout AJ.

Genome Res. 2007 Jul;17(7):1061-71. Epub 2007 May 18.

27.

EDGEdb: a transcription factor-DNA interaction database for the analysis of C. elegans differential gene expression.

Barrasa MI, Vaglio P, Cavasino F, Jacotot L, Walhout AJ.

BMC Genomics. 2007 Jan 18;8:21.

30.

Conditional replication of duck hepatitis B virus in hepatoma cells.

Guo JT, Pryce M, Wang X, Barrasa MI, Hu J, Seeger C.

J Virol. 2003 Feb;77(3):1885-93.

31.
32.

Apoptosis and regeneration of hepatocytes during recovery from transient hepadnavirus infections.

Guo JT, Zhou H, Liu C, Aldrich C, Saputelli J, Whitaker T, Barrasa MI, Mason WS, Seeger C.

J Virol. 2000 Feb;74(3):1495-505.

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