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Items: 43

1.

Protein folding. Translational tuning optimizes nascent protein folding in cells.

Kim SJ, Yoon JS, Shishido H, Yang Z, Rooney LA, Barral JM, Skach WR.

Science. 2015 Apr 24;348(6233):444-8. doi: 10.1126/science.aaa3974.

2.

Thermally-induced structural changes in an armadillo repeat protein suggest a novel thermosensor mechanism in a molecular chaperone.

Bujalowski PJ, Nicholls P, Barral JM, Oberhauser AF.

FEBS Lett. 2015 Jan 2;589(1):123-30. doi: 10.1016/j.febslet.2014.11.034. Epub 2014 Nov 29.

3.

Chaperone-mediated reversible inhibition of the sarcomeric myosin power stroke.

Nicholls P, Bujalowski PJ, Epstein HF, Boehning DF, Barral JM, Oberhauser AF.

FEBS Lett. 2014 Nov 3;588(21):3977-81. doi: 10.1016/j.febslet.2014.09.013. Epub 2014 Sep 19.

4.

Non-optimal codon usage affects expression, structure and function of clock protein FRQ.

Zhou M, Guo J, Cha J, Chae M, Chen S, Barral JM, Sachs MS, Liu Y.

Nature. 2013 Mar 7;495(7439):111-5. doi: 10.1038/nature11833. Epub 2013 Feb 17.

5.

Ubiquilin-1 and protein quality control in Alzheimer disease.

El Ayadi A, Stieren ES, Barral JM, Boehning D.

Prion. 2013 Mar-Apr;7(2):164-9. doi: 10.4161/pri.23711. Epub 2013 Jan 29.

6.

Caspase 3 cleavage of the inositol 1,4,5-trisphosphate receptor does not contribute to apoptotic calcium release.

Akimzhanov AM, Barral JM, Boehning D.

Cell Calcium. 2013 Feb;53(2):152-8. doi: 10.1016/j.ceca.2012.10.002. Epub 2012 Nov 2.

7.

Purification and aggregation of the amyloid precursor protein intracellular domain.

El Ayadi A, Stieren ES, Barral JM, Oberhauser AF, Boehning D.

J Vis Exp. 2012 Aug 28;(66):e4204. doi: 10.3791/4204.

8.

Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688.

El Ayadi A, Stieren ES, Barral JM, Boehning D.

Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13416-21. doi: 10.1073/pnas.1206786109. Epub 2012 Jul 30.

9.

Silent substitutions predictably alter translation elongation rates and protein folding efficiencies.

Spencer PS, Siller E, Anderson JF, Barral JM.

J Mol Biol. 2012 Sep 21;422(3):328-35. doi: 10.1016/j.jmb.2012.06.010. Epub 2012 Jun 12.

10.

Genetic code redundancy and its influence on the encoded polypeptides.

Spencer PS, Barral JM.

Comput Struct Biotechnol J. 2012 Mar 20;1:e201204006. doi: 10.5936/csbj.201204006. eCollection 2012. Review.

11.

Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein.

Stieren ES, El Ayadi A, Xiao Y, Siller E, Landsverk ML, Oberhauser AF, Barral JM, Boehning D.

J Biol Chem. 2011 Oct 14;286(41):35689-98. doi: 10.1074/jbc.M111.243147. Epub 2011 Aug 18.

12.

The neurodegenerative-disease-related protein sacsin is a molecular chaperone.

Anderson JF, Siller E, Barral JM.

J Mol Biol. 2011 Aug 26;411(4):870-80. doi: 10.1016/j.jmb.2011.06.016. Epub 2011 Jun 25.

PMID:
21726565
13.

Disorders of protein biogenesis and stability.

Anderson JF, Siller E, Barral JM.

Protein Pept Lett. 2011 Feb;18(2):110-21. Review.

PMID:
21121895
14.

The sacsin repeating region (SRR): a novel Hsp90-related supra-domain associated with neurodegeneration.

Anderson JF, Siller E, Barral JM.

J Mol Biol. 2010 Jul 23;400(4):665-74. doi: 10.1016/j.jmb.2010.05.023. Epub 2010 May 19. Review.

PMID:
20488193
15.

Post-burn hepatic insulin resistance is associated with endoplasmic reticulum (ER) stress.

Gauglitz GG, Halder S, Boehning DF, Kulp GA, Herndon DN, Barral JM, Jeschke MG.

Shock. 2010 Mar;33(3):299-305. doi: 10.1097/SHK.0b013e3181b2f439.

16.

Calcium and ER stress mediate hepatic apoptosis after burn injury.

Jeschke MG, Gauglitz GG, Song J, Kulp GA, Finnerty CC, Cox RA, Barral JM, Herndon DN, Boehning D.

J Cell Mol Med. 2009 Aug;13(8B):1857-65. doi: 10.1111/j.1582-4934.2009.00644.x.

17.

Slowing bacterial translation speed enhances eukaryotic protein folding efficiency.

Siller E, DeZwaan DC, Anderson JF, Freeman BC, Barral JM.

J Mol Biol. 2010 Mar 12;396(5):1310-8. doi: 10.1016/j.jmb.2009.12.042. Epub 2010 Jan 4.

PMID:
20043920
18.

Clinical significance of V617F mutation of the JAK2 gene in patients with chronic myeloproliferative disorders.

Basquiera AL, Soria NW, Ryser R, Salguero M, Moiraghi B, Sackmann F, Sturich AG, Borello A, Berretta A, Bonafé M, Barral JM, Palazzo ED, García JJ.

Hematology. 2009 Dec;14(6):323-30. doi: 10.1179/102453309X12473408860226.

PMID:
19941738
19.

Characterization of the inflammatory response during acute and post-acute phases after severe burn.

Gauglitz GG, Song J, Herndon DN, Finnerty CC, Boehning D, Barral JM, Jeschke MG.

Shock. 2008 Nov;30(5):503-7. doi: 10.1097/SHK.0b013e31816e3373.

PMID:
18391855
20.

Requirement of inositol 1,4,5-trisphosphate receptors for tumor-mediated lymphocyte apoptosis.

Steinmann C, Landsverk ML, Barral JM, Boehning D.

J Biol Chem. 2008 May 16;283(20):13506-9. doi: 10.1074/jbc.C800029200. Epub 2008 Mar 25.

21.

Program for the conservation and promotion of hearing among adolescents.

Serra MR, Biassoni EC, Hinalaf M, Pavlik M, Villalobo JP, Curet C, Minoldo G, Abraham S, Barral JM, Reynoso R, Barteik ME, Joekes S, Yacci MR.

Am J Audiol. 2007 Dec;16(2):S158-64.

PMID:
18056869
22.

Accuracy of leukocyte alkaline phosphatase score to predict JAK2 V617F mutation.

Basquiera AL, Fassetta F, Soria N, Barral JM, Ricchi B, García JJ.

Haematologica. 2007 May;92(5):704-5.

23.

The UNC-45 chaperone mediates sarcomere assembly through myosin degradation in Caenorhabditis elegans.

Landsverk ML, Li S, Hutagalung AH, Najafov A, Hoppe T, Barral JM, Epstein HF.

J Cell Biol. 2007 Apr 23;177(2):205-10. Epub 2007 Apr 16.

24.

Identification of nascent chain interaction sites on trigger factor.

Lakshmipathy SK, Tomic S, Kaiser CM, Chang HC, Genevaux P, Georgopoulos C, Barral JM, Johnson AE, Hartl FU, Etchells SA.

J Biol Chem. 2007 Apr 20;282(16):12186-93. Epub 2007 Feb 12.

25.

Real-time observation of trigger factor function on translating ribosomes.

Kaiser CM, Chang HC, Agashe VR, Lakshmipathy SK, Etchells SA, Hayer-Hartl M, Hartl FU, Barral JM.

Nature. 2006 Nov 23;444(7118):455-60. Epub 2006 Oct 15.

PMID:
17051157
26.
27.

De novo folding of GFP fusion proteins: high efficiency in eukaryotes but not in bacteria.

Chang HC, Kaiser CM, Hartl FU, Barral JM.

J Mol Biol. 2005 Oct 21;353(2):397-409.

PMID:
16171814
28.

Regulation of the myosin-directed chaperone UNC-45 by a novel E3/E4-multiubiquitylation complex in C. elegans.

Hoppe T, Cassata G, Barral JM, Springer W, Hutagalung AH, Epstein HF, Baumeister R.

Cell. 2004 Aug 6;118(3):337-49.

29.

Function of trigger factor and DnaK in multidomain protein folding: increase in yield at the expense of folding speed.

Agashe VR, Guha S, Chang HC, Genevaux P, Hayer-Hartl M, Stemp M, Georgopoulos C, Hartl FU, Barral JM.

Cell. 2004 Apr 16;117(2):199-209.

30.

Roles of molecular chaperones in protein misfolding diseases.

Barral JM, Broadley SA, Schaffar G, Hartl FU.

Semin Cell Dev Biol. 2004 Feb;15(1):17-29. Review.

PMID:
15036203
31.

Trypanosoma cruzi in persons without serologic evidence of disease, Argentina.

Salomone OA, Basquiera AL, Sembaj A, Aguerri AM, Reyes ME, Omelianuk M, Fernández RA, Enders J, Palma A, Barral JM, Madoery RJ.

Emerg Infect Dis. 2003 Dec;9(12):1558-62.

32.

More than folding: localized functions of cytosolic chaperones.

Young JC, Barral JM, Ulrich Hartl F.

Trends Biochem Sci. 2003 Oct;28(10):541-7. Review.

PMID:
14559183
33.

Two mammalian UNC-45 isoforms are related to distinct cytoskeletal and muscle-specific functions.

Price MG, Landsverk ML, Barral JM, Epstein HF.

J Cell Sci. 2002 Nov 1;115(Pt 21):4013-23.

34.

Association analysis of genotypic frequencies of matrilin-1 gene in patients with osteoarthritis.

Strusberg I, Sembaj A, Tabares S, Strusberg AM, del Castillo I, Villamar M, Barral JM.

Clin Exp Rheumatol. 2002 Jul-Aug;20(4):543-5.

PMID:
12175111
35.

Role of the myosin assembly protein UNC-45 as a molecular chaperone for myosin.

Barral JM, Hutagalung AH, Brinker A, Hartl FU, Epstein HF.

Science. 2002 Jan 25;295(5555):669-71.

36.

Prevalence of circulating Trypanosoma cruzi detected by polymerase chain reaction in patients with Chagas' cardiomyopathy.

Salomone OA, Juri D, Omelianiuk MO, Sembaj A, Aguerri AM, Carriazo C, Barral JM, Madoery R.

Am J Cardiol. 2000 May 15;85(10):1274-6. No abstract available.

PMID:
10802020
37.

Alkaline phosphatase isoenzymes in plasma of chagasic and healthy pregnant women.

Sembaj A, Sanz E, Castro I, Gonzalez A, Carriazo C, Barral JM.

Mem Inst Oswaldo Cruz. 1999 Nov-Dec;94(6):785-6. No abstract available.

38.

Protein machines and self assembly in muscle organization.

Barral JM, Epstein HF.

Bioessays. 1999 Oct;21(10):813-23. Review.

PMID:
10497331
39.

Unc-45 mutations in Caenorhabditis elegans implicate a CRO1/She4p-like domain in myosin assembly.

Barral JM, Bauer CC, Ortiz I, Epstein HF.

J Cell Biol. 1998 Nov 30;143(5):1215-25.

40.

Polymerase chain reaction procedure to detect Trypanosoma cruzi in blood samples from chronic chagasic patients.

Carriazo CS, Sembaj A, Aguerri AM, Requena JM, Alonso C, Búa J, Ruiz A, Segura E, Barral JM.

Diagn Microbiol Infect Dis. 1998 Mar;30(3):183-6.

PMID:
9572024
41.

Assemblases and coupling proteins in thick filament assembly.

Liu F, Barral JM, Bauer CC, Ortiz I, Cook RG, Schmid MF, Epstein HF.

Cell Struct Funct. 1997 Feb;22(1):155-62.

42.
43.

Effect of alpha-interferon on erythrocyte and hepatocyte plasma membranes derived from cirrhotic rats.

Muriel P, Bolaños J, Barral JM, Torres G.

Pharmacology. 1994 Jan;48(1):63-8.

PMID:
8309989

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