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Items: 1 to 50 of 156

1.

Associations between persistent organic pollutants and risk of breast cancer metastasis.

Koual M, Cano-Sancho G, Bats AS, Tomkiewicz C, Kaddouch-Amar Y, Douay-Hauser N, Ngo C, Bonsang H, Deloménie M, Lecuru F, Le Bizec B, Marchand P, Botton J, Barouki R, Antignac JP, Coumoul X.

Environ Int. 2019 Aug 2;132:105028. doi: 10.1016/j.envint.2019.105028. [Epub ahead of print]

2.

sAOP: Linking chemical stressors to Adverse Outcomes Pathway Networks.

Aguayo-Orozco A, Audouze K, Siggaard T, Barouki R, Brunak S, Taboureau O.

Bioinformatics. 2019 Jul 22. pii: btz570. doi: 10.1093/bioinformatics/btz570. [Epub ahead of print]

PMID:
31329252
3.

Structural basis for substrate selectivity and nucleophilic substitution mechanisms in human adenine phosphoribosyltransferase catalyzed reaction.

Ozeir M, Huyet J, Burgevin MC, Pinson B, Chesney F, Remy JM, Siddiqi AR, Lupoli R, Pinon G, Saint-Marc C, Gibert JF, Morales R, Ceballos-Picot I, Barouki R, Daignan-Fornier B, Olivier-Bandini A, Augé F, Nioche P.

J Biol Chem. 2019 Aug 9;294(32):11980-11991. doi: 10.1074/jbc.RA119.009087. Epub 2019 Jun 3.

4.

Linking Bisphenol S to Adverse Outcome Pathways Using a Combined Text Mining and Systems Biology Approach.

Carvaillo JC, Barouki R, Coumoul X, Audouze K.

Environ Health Perspect. 2019 Apr;127(4):47005. doi: 10.1289/EHP4200.

5.

[Endocrine disruptor compounds and new mechanisms of toxicity networks].

Barouki R.

Rev Prat. 2018 Dec;68(10):1069-1074. French.

PMID:
30869210
6.

Determination of bisphenol A and bisphenol S concentrations and assessment of estrogen- and anti-androgen-like activities in thermal paper receipts from Brazil, France, and Spain.

Molina-Molina JM, Jiménez-Díaz I, Fernández MF, Rodriguez-Carrillo A, Peinado FM, Mustieles V, Barouki R, Piccoli C, Olea N, Freire C.

Environ Res. 2019 Mar;170:406-415. doi: 10.1016/j.envres.2018.12.046. Epub 2018 Dec 21.

PMID:
30623888
7.

The 9th Santorini Conference: Systems Medicine, Personalised Health and Therapy. "The Odyssey from Hope to Practice", Santorini, Greece, 30 September⁻3 October 2018.

Visvikis-Siest S, Gorenjak V, Stathopoulou MG, Petrelis AM, Weryha G, Masson C, Hiegel B, Kumar S, Barouki R, Boerwinkle E, Dagher G, Deloukas P, Innocenti F, Lamont J, Marschler M, Meyer H, Meyer UA, Nofziger C, Paulmichl M, Vacher C, Webster L.

J Pers Med. 2018 Dec 12;8(4). pii: E43. doi: 10.3390/jpm8040043.

8.

The GMO90+ Project: Absence of Evidence for Biologically Meaningful Effects of Genetically Modified Maize-based Diets on Wistar Rats After 6-Months Feeding Comparative Trial.

Coumoul X, Servien R, Juricek L, Kaddouch-Amar Y, Lippi Y, Berthelot L, Naylies C, Morvan ML, Antignac JP, Desdoits-Lethimonier C, Jegou B, Tremblay-Franco M, Canlet C, Debrauwer L, Le Gall C, Laurent J, Gouraud PA, Cravedi JP, Jeunesse E, Savy N, Dandere-Abdoulkarim K, Arnich N, Fourès F, Cotton J, Broudin S, Corman B, Moing A, Laporte B, Richard-Forget F, Barouki R, Rogowsky P, Salles B.

Toxicol Sci. 2019 Apr 1;168(2):315-338. doi: 10.1093/toxsci/kfy298.

9.

Old Receptor, New Tricks-The Ever-Expanding Universe of Aryl Hydrocarbon Receptor Functions. Report from the 4th AHR Meeting, 29⁻31 August 2018 in Paris, France.

Esser C, Lawrence BP, Sherr DH, Perdew GH, Puga A, Barouki R, Coumoul X.

Int J Mol Sci. 2018 Nov 15;19(11). pii: E3603. doi: 10.3390/ijms19113603.

10.

Release and toxicity of adipose tissue-stored TCDD: Direct evidence from a xenografted fat model.

Joffin N, Noirez P, Antignac JP, Kim MJ, Marchand P, Falabregue M, Le Bizec B, Forest C, Emond C, Barouki R, Coumoul X.

Environ Int. 2018 Dec;121(Pt 2):1113-1120. doi: 10.1016/j.envint.2018.10.027. Epub 2018 Oct 31.

11.

Timescales of developmental toxicity impacting on research and needs for intervention.

Grandjean P, Abdennebi-Najar L, Barouki R, Cranor CF, Etzel RA, Gee D, Heindel JJ, Hougaard KS, Hunt P, Nawrot TS, Prins GS, Ritz B, Soffritti M, Sunyer J, Weihe P.

Basic Clin Pharmacol Toxicol. 2019 Aug;125 Suppl 3:70-80. doi: 10.1111/bcpt.13162. Epub 2018 Dec 10. Review.

12.

Current EU research activities on combined exposure to multiple chemicals.

Bopp SK, Barouki R, Brack W, Dalla Costa S, Dorne JCM, Drakvik PE, Faust M, Karjalainen TK, Kephalopoulos S, van Klaveren J, Kolossa-Gehring M, Kortenkamp A, Lebret E, Lettieri T, Nørager S, Rüegg J, Tarazona JV, Trier X, van de Water B, van Gils J, Bergman Å.

Environ Int. 2018 Nov;120:544-562. doi: 10.1016/j.envint.2018.07.037. Epub 2018 Aug 28. Review.

13.

[Regulatory science in public health: What are we talking about?]

Camadro M, Benamouzig D, Barouki R, Trouvin JH, Astagneau P.

Sante Publique. 2018 March April;30(2):187-196. doi: 10.3917/spub.182.0187. French.

PMID:
30148306
14.

Hypoglycemic Toxins and Enteroviruses as Causes of Outbreaks of Acute Encephalitis-Like Syndrome in Children, Bac Giang Province, Northern Vietnam.

Phan NT, Gouilh MA, Paireau J, Phuong L, Cheval J, Ngu ND, Hébert C, Nguyen TH, Lortholary O, Tondeur L, Manuguerra JC, Barouki R, Sander J, Janzen N, Nguyen HT, Brey PT, Fontanet A, Eloit M.

Emerg Infect Dis. 2018 Aug;24(8):1435-1443. doi: 10.3201/eid2408.171004.

15.

Integration of the human exposome with the human genome to advance medicine.

Barouki R, Audouze K, Coumoul X, Demenais F, Gauguier D.

Biochimie. 2018 Sep;152:155-158. doi: 10.1016/j.biochi.2018.06.023. Epub 2018 Jun 28. Review.

PMID:
29960033
16.

Promoting respiratory public health through epigenetics research: an ERS Environment Health Committee workshop report.

Melén E, Barouki R, Barry M, Boezen HM, Hoffmann B, Krauss-Etschmann S, Koppelman GH, Forsberg B.

Eur Respir J. 2018 Apr 4;51(4). pii: 1702410. doi: 10.1183/13993003.02410-2017. Print 2018 Apr. No abstract available.

PMID:
29618601
17.

Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase.

Huyet J, Ozeir M, Burgevin MC, Pinson B, Chesney F, Remy JM, Siddiqi AR, Lupoli R, Pinon G, Saint-Marc C, Gibert JF, Morales R, Ceballos-Picot I, Barouki R, Daignan-Fornier B, Olivier-Bandini A, Augé F, Nioche P.

Cell Chem Biol. 2018 Jun 21;25(6):666-676.e4. doi: 10.1016/j.chembiol.2018.02.011. Epub 2018 Mar 22.

18.

Epigenetics as a mechanism linking developmental exposures to long-term toxicity.

Barouki R, Melén E, Herceg Z, Beckers J, Chen J, Karagas M, Puga A, Xia Y, Chadwick L, Yan W, Audouze K, Slama R, Heindel J, Grandjean P, Kawamoto T, Nohara K.

Environ Int. 2018 May;114:77-86. doi: 10.1016/j.envint.2018.02.014. Epub 2018 Feb 27. Review.

19.

Endocrine disruptors: Revisiting concepts and dogma in toxicology.

Barouki R.

C R Biol. 2017 Sep - Oct;340(9-10):410-413. doi: 10.1016/j.crvi.2017.07.005.

20.

AhR-deficiency as a cause of demyelinating disease and inflammation.

Juricek L, Carcaud J, Pelhaitre A, Riday TT, Chevallier A, Lanzini J, Auzeil N, Laprévote O, Dumont F, Jacques S, Letourneur F, Massaad C, Agulhon C, Barouki R, Beraneck M, Coumoul X.

Sci Rep. 2017 Aug 29;7(1):9794. doi: 10.1038/s41598-017-09621-3.

21.

Resveratrol reverses the Warburg effect by targeting the pyruvate dehydrogenase complex in colon cancer cells.

Saunier E, Antonio S, Regazzetti A, Auzeil N, Laprévote O, Shay JW, Coumoul X, Barouki R, Benelli C, Huc L, Bortoli S.

Sci Rep. 2017 Jul 31;7(1):6945. doi: 10.1038/s41598-017-07006-0.

22.

Biallelic Mutations in LIPT2 Cause a Mitochondrial Lipoylation Defect Associated with Severe Neonatal Encephalopathy.

Habarou F, Hamel Y, Haack TB, Feichtinger RG, Lebigot E, Marquardt I, Busiah K, Laroche C, Madrange M, Grisel C, Pontoizeau C, Eisermann M, Boutron A, Chrétien D, Chadefaux-Vekemans B, Barouki R, Bole-Feysot C, Nitschke P, Goudin N, Boddaert N, Nemazanyy I, Delahodde A, Kölker S, Rodenburg RJ, Korenke GC, Meitinger T, Strom TM, Prokisch H, Rotig A, Ottolenghi C, Mayr JA, de Lonlay P.

Am J Hum Genet. 2017 Aug 3;101(2):283-290. doi: 10.1016/j.ajhg.2017.07.001. Epub 2017 Jul 27.

23.

Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells.

Attignon EA, Distel E, Le-Grand B, Leblanc AF, Barouki R, de Oliveira E, Aggerbeck M, Blanc EB.

Toxicol In Vitro. 2017 Dec;45(Pt 3):309-317. doi: 10.1016/j.tiv.2017.06.029. Epub 2017 Jul 1.

PMID:
28673560
24.

Human biomonitoring as a tool to support chemicals regulation in the European Union.

Ganzleben C, Antignac JP, Barouki R, Castaño A, Fiddicke U, Klánová J, Lebret E, Olea N, Sarigiannis D, Schoeters GR, Sepai O, Tolonen H, Kolossa-Gehring M.

Int J Hyg Environ Health. 2017 Mar;220(2 Pt A):94-97. doi: 10.1016/j.ijheh.2017.01.007. Epub 2017 Feb 22. No abstract available.

PMID:
28284775
25.

Chronic Exposure to Low Doses of Dioxin Promotes Liver Fibrosis Development in the C57BL/6J Diet-Induced Obesity Mouse Model.

Duval C, Teixeira-Clerc F, Leblanc AF, Touch S, Emond C, Guerre-Millo M, Lotersztajn S, Barouki R, Aggerbeck M, Coumoul X.

Environ Health Perspect. 2017 Mar;125(3):428-436. doi: 10.1289/EHP316. Epub 2016 Oct 7.

26.

Determination of Heavy Metal Concentrations in Normal and Pathological Human Endometrial Biopsies and In Vitro Regulation of Gene Expression by Metals in the Ishikawa and Hec-1b Endometrial Cell Line.

Guyot E, Solovyova Y, Tomkiewicz C, Leblanc A, Pierre S, El Balkhi S, Le Frère-Belda MA, Lecuru F, Poupon J, Barouki R, Aggerbeck M, Coumoul X.

PLoS One. 2015 Nov 23;10(11):e0142590. doi: 10.1371/journal.pone.0142590. eCollection 2015.

27.

Regulation of Aquaporin 3 Expression by the AhR Pathway Is Critical to Cell Migration.

Bui LC, Tomkiewicz C, Pierre S, Chevallier A, Barouki R, Coumoul X.

Toxicol Sci. 2016 Jan;149(1):158-66. doi: 10.1093/toxsci/kfv221. Epub 2015 Oct 9.

PMID:
26454884
28.

Hyperprolinemia in Type 2 Glutaric Aciduria and MADD-Like Profiles.

Pontoizeau C, Habarou F, Brassier A, Veauville-Merllié A, Grisel C, Arnoux JB, Vianey-Saban C, Barouki R, Chadefaux-Vekemans B, Acquaviva C, de Lonlay P, Ottolenghi C.

JIMD Rep. 2016;27:39-45. doi: 10.1007/8904_2015_481. Epub 2015 Sep 27.

29.

Life-Long Implications of Developmental Exposure to Environmental Stressors: New Perspectives.

Grandjean P, Barouki R, Bellinger DC, Casteleyn L, Chadwick LH, Cordier S, Etzel RA, Gray KA, Ha EH, Junien C, Karagas M, Kawamoto T, Paige Lawrence B, Perera FP, Prins GS, Puga A, Rosenfeld CS, Sherr DH, Sly PD, Suk W, Sun Q, Toppari J, van den Hazel P, Walker CL, Heindel JJ.

Endocrinology. 2015 Oct;156(10):3408-15. doi: 10.1210/EN.2015-1350. Epub 2015 Aug 4.

30.

Acute induction of uncoupling protein 1 by citrulline in cultured explants of white adipose tissue from lean and high-fat-diet-fed rats.

Joffin N, Jaubert AM, Bamba J, Barouki R, Noirez P, Forest C.

Adipocyte. 2015 Jan 7;4(2):129-34. doi: 10.4161/21623945.2014.989748. eCollection 2015 Apr-Jun.

31.

Two persistent organic pollutants which act through different xenosensors (alpha-endosulfan and 2,3,7,8 tetrachlorodibenzo-p-dioxin) interact in a mixture and downregulate multiple genes involved in human hepatocyte lipid and glucose metabolism.

Ambolet-Camoit A, Ottolenghi C, Leblanc A, Kim MJ, Letourneur F, Jacques S, Cagnard N, Guguen-Guillouzo C, Barouki R, Aggerbeck M.

Biochimie. 2015 Sep;116:79-91. doi: 10.1016/j.biochi.2015.07.003. Epub 2015 Jul 6.

32.

Health can help saving negotiation on climate change.

Flahault A, Schütte S, Guégan JF, Pascal M, Barouki R.

Lancet. 2015 Jun 13;385(9985):e49-50. doi: 10.1016/S0140-6736(15)60866-2. No abstract available.

PMID:
26088645
33.

A generic methodological framework for studying single cell motility in high-throughput time-lapse data.

Schoenauer Sebag A, Plancade S, Raulet-Tomkiewicz C, Barouki R, Vert JP, Walter T.

Bioinformatics. 2015 Jun 15;31(12):i320-8. doi: 10.1093/bioinformatics/btv225.

34.

Citrulline counteracts overweight- and aging-related effects on adiponectin and leptin gene expression in rat white adipose tissue.

Joffin N, Jaubert AM, Durant S, Barouki R, Forest C, Noirez P.

Biochim Open. 2015 Jun 5;1:1-5. doi: 10.1016/j.biopen.2015.05.001. eCollection 2015.

35.

Contiguous mutation syndrome in the era of high-throughput sequencing.

Langouët M, Siquier-Pernet K, Sanquer S, Bole-Feysot C, Nitschke P, Boddaert N, Munnich A, Mancini GM, Barouki R, Amiel J, Colleaux L.

Mol Genet Genomic Med. 2015 May;3(3):215-20. doi: 10.1002/mgg3.134. Epub 2015 Mar 18.

36.

Long-term outcomes in Ornithine Transcarbamylase deficiency: a series of 90 patients.

Brassier A, Gobin S, Arnoux JB, Valayannopoulos V, Habarou F, Kossorotoff M, Servais A, Barbier V, Dubois S, Touati G, Barouki R, Lesage F, Dupic L, Bonnefont JP, Ottolenghi C, De Lonlay P.

Orphanet J Rare Dis. 2015 May 10;10:58. doi: 10.1186/s13023-015-0266-1.

37.

Pyruvate carboxylase deficiency: An underestimated cause of lactic acidosis.

Habarou F, Brassier A, Rio M, Chrétien D, Monnot S, Barbier V, Barouki R, Bonnefont JP, Boddaert N, Chadefaux-Vekemans B, Le Moyec L, Bastin J, Ottolenghi C, de Lonlay P.

Mol Genet Metab Rep. 2014 Nov 28;2:25-31. doi: 10.1016/j.ymgmr.2014.11.001. eCollection 2015 Mar.

38.

Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated metabolites.

Juricek L, Bui LC, Busi F, Pierre S, Guyot E, Lamouri A, Dupret JM, Barouki R, Coumoul X, Rodrigues-Lima F.

Arch Toxicol. 2015 Dec;89(12):2403-12. doi: 10.1007/s00204-014-1367-7. Epub 2014 Sep 17.

PMID:
25224404
39.

Serum 2-hydroxyglutarate production in IDH1- and IDH2-mutated de novo acute myeloid leukemia: a study by the Acute Leukemia French Association group.

Janin M, Mylonas E, Saada V, Micol JB, Renneville A, Quivoron C, Koscielny S, Scourzic L, Forget S, Pautas C, Caillot D, Preudhomme C, Dombret H, Berthon C, Barouki R, Rabier D, Auger N, Griscelli F, Chachaty E, Leclercq E, Courtier MH, Bennaceur-Griscelli A, Solary E, Bernard OA, Penard-Lacronique V, Ottolenghi C, de Botton S.

J Clin Oncol. 2014 Feb 1;32(4):297-305. doi: 10.1200/JCO.2013.50.2047. Epub 2013 Dec 16.

PMID:
24344214
40.

Aryl hydrocarbon receptor-dependent induction of liver fibrosis by dioxin.

Pierre S, Chevallier A, Teixeira-Clerc F, Ambolet-Camoit A, Bui LC, Bats AS, Fournet JC, Fernandez-Salguero P, Aggerbeck M, Lotersztajn S, Barouki R, Coumoul X.

Toxicol Sci. 2014 Jan;137(1):114-24. doi: 10.1093/toxsci/kft236. Epub 2013 Oct 23.

PMID:
24154488
41.

Viewing drug action as network perturbation in multiple scale systems.

Barouki R.

Drug Metabol Drug Interact. 2013;28(2):65-6. doi: 10.1515/dmdi-2013-0025. No abstract available.

PMID:
23740682
42.

[Can xenobiotics accumulated in adipose tissue contribute to a carcinogenic risk?].

Barouki R.

Ann Endocrinol (Paris). 2013 May;74(2):154-5. doi: 10.1016/j.ando.2013.03.022. Epub 2013 Apr 12. Review. French.

PMID:
23587352
43.

[Environment and health: the lessons of pesticides].

Barouki R.

Med Sci (Paris). 2013 Mar;29(3):235-6. doi: 10.1051/medsci/2013293001. Epub 2013 Mar 27. French. No abstract available.

44.

Expression of calcineurin activity after lung transplantation: a 2-year follow-up.

Sanquer S, Amrein C, Grenet D, Guillemain R, Philippe B, Boussaud V, Herry L, Lena C, Diouf A, Paunet M, Billaud EM, Loriaux F, Jais JP, Barouki R, Stern M.

PLoS One. 2013;8(3):e59634. doi: 10.1371/journal.pone.0059634. Epub 2013 Mar 25.

45.

Oculomotor deficits in aryl hydrocarbon receptor null mouse.

Chevallier A, Mialot A, Petit JM, Fernandez-Salguero P, Barouki R, Coumoul X, Beraneck M.

PLoS One. 2013;8(1):e53520. doi: 10.1371/journal.pone.0053520. Epub 2013 Jan 3.

46.

Early-life prevention of non-communicable diseases.

Balbus JM, Barouki R, Birnbaum LS, Etzel RA, Gluckman PD Sr, Grandjean P, Hancock C, Hanson MA, Heindel JJ, Hoffman K, Jensen GK, Keeling A, Neira M, Rabadán-Diehl C, Ralston J, Tang KC.

Lancet. 2013 Jan 5;381(9860):3-4. doi: 10.1016/S0140-6736(12)61609-2. No abstract available.

47.

Toxicological function of adipose tissue: focus on persistent organic pollutants.

La Merrill M, Emond C, Kim MJ, Antignac JP, Le Bizec B, Clément K, Birnbaum LS, Barouki R.

Environ Health Perspect. 2013 Feb;121(2):162-9. doi: 10.1289/ehp.1205485. Epub 2012 Dec 5. Review.

48.

The AhR twist: ligand-dependent AhR signaling and pharmaco-toxicological implications.

Guyot E, Chevallier A, Barouki R, Coumoul X.

Drug Discov Today. 2013 May;18(9-10):479-86. doi: 10.1016/j.drudis.2012.11.014. Epub 2012 Dec 6. Review.

PMID:
23220635
49.

A head and neck cancer tumor response-specific gene signature for cisplatin, 5-fluorouracil induction chemotherapy fails with added taxanes.

Tomkiewicz C, Hans S, Mucchielli MH, Agier N, Delacroix H, Marisa L, Brasnu D, Aggerbeck LP, Badoual C, Barouki R, Aggerbeck M.

PLoS One. 2012;7(10):e47170. doi: 10.1371/journal.pone.0047170. Epub 2012 Oct 9.

50.

PPTOX III: environmental stressors in the developmental origins of disease--evidence and mechanisms.

Schug TT, Barouki R, Gluckman PD, Grandjean P, Hanson M, Heindel JJ.

Toxicol Sci. 2013 Feb;131(2):343-50. doi: 10.1093/toxsci/kfs267. Epub 2012 Sep 5.

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