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Items: 1 to 50 of 166

1.

Pluripotential stem cells as replacement therapy in degenerative diseases of the eye.

Barnstable CJ.

Ann Transl Med. 2019 Jul;7(Suppl 3):S156. doi: 10.21037/atm.2019.06.50. No abstract available.

2.

Cell Autonomous Neuroprotection by the Mitochondrial Uncoupling Protein 2 in a Mouse Model of Glaucoma.

Hass DT, Barnstable CJ.

Front Neurosci. 2019 Mar 8;13:201. doi: 10.3389/fnins.2019.00201. eCollection 2019.

3.

Mitochondrial Uncoupling Protein 2 Knock-out Promotes Mitophagy to Decrease Retinal Ganglion Cell Death in a Mouse Model of Glaucoma.

Hass DT, Barnstable CJ.

J Neurosci. 2019 May 1;39(18):3582-3596. doi: 10.1523/JNEUROSCI.2702-18.2019. Epub 2019 Feb 27.

4.

Pluripotent Stem Cells as Models of Retina Development.

Lu AQ, Barnstable CJ.

Mol Neurobiol. 2019 Sep;56(9):6056-6070. doi: 10.1007/s12035-019-1504-7. Epub 2019 Feb 4. Review.

PMID:
30715650
5.

The 3-Phosphoinositide-Dependent Protein Kinase 1 Inhibits Rod Photoreceptor Development.

Xing T, Hass DT, Zhang SS, Barnstable CJ.

Front Cell Dev Biol. 2018 Oct 10;6:134. doi: 10.3389/fcell.2018.00134. eCollection 2018.

6.

Perineuronal nets labeled by monoclonal antibody VC1.1 ensheath interneurons expressing parvalbumin and calbindin in the rat amygdala.

McDonald AJ, Hamilton PG, Barnstable CJ.

Brain Struct Funct. 2018 Apr;223(3):1133-1148. doi: 10.1007/s00429-017-1542-8. Epub 2017 Nov 1.

7.

Generation of Photoreceptor Precursors from Mouse Embryonic Stem Cells.

Lu AQ, Barnstable CJ.

Stem Cell Rev Rep. 2018 Apr;14(2):247-261. doi: 10.1007/s12015-017-9773-x.

PMID:
29047024
8.

Activin Signals through SMAD2/3 to Increase Photoreceptor Precursor Yield during Embryonic Stem Cell Differentiation.

Lu AQ, Popova EY, Barnstable CJ.

Stem Cell Reports. 2017 Sep 12;9(3):838-852. doi: 10.1016/j.stemcr.2017.06.021. Epub 2017 Aug 3.

9.

Identification and prediction of alternative transcription start sites that generate rod photoreceptor-specific transcripts from ubiquitously expressed genes.

Popova EY, Salzberg AC, Yang C, Zhang SS, Barnstable CJ.

PLoS One. 2017 Jun 22;12(6):e0179230. doi: 10.1371/journal.pone.0179230. eCollection 2017.

10.

Histone Deacetylase 1 Is Essential for Rod Photoreceptor Differentiation by Regulating Acetylation at Histone H3 Lysine 9 and Histone H4 Lysine 12 in the Mouse Retina.

Ferreira RC, Popova EY, James J, Briones MR, Zhang SS, Barnstable CJ.

J Biol Chem. 2017 Feb 10;292(6):2422-2440. doi: 10.1074/jbc.M116.756643. Epub 2016 Dec 27.

11.

Uncoupling protein 2 in the glial response to stress: implications for neuroprotection.

Hass DT, Barnstable CJ.

Neural Regen Res. 2016 Aug;11(8):1197-200. doi: 10.4103/1673-5374.189159. Review.

12.

Mitochondrial Uncoupling Protein 2 (UCP2) Regulates Retinal Ganglion Cell Number and Survival.

Barnstable CJ, Reddy R, Li H, Horvath TL.

J Mol Neurosci. 2016 Apr;58(4):461-9. doi: 10.1007/s12031-016-0728-5. Epub 2016 Feb 5.

13.

LSD1-Mediated Demethylation of H3K4me2 Is Required for the Transition from Late Progenitor to Differentiated Mouse Rod Photoreceptor.

Popova EY, Pinzon-Guzman C, Salzberg AC, Zhang SS, Barnstable CJ.

Mol Neurobiol. 2016 Sep;53(7):4563-81. doi: 10.1007/s12035-015-9395-8. Epub 2015 Aug 23.

PMID:
26298666
14.

Therapeutic Retrobulbar Inhibition of STAT3 Protects Ischemic Retina Ganglion Cells.

Wong M, Li Y, Li S, Zhang S, Li W, Zhang P, Chen C, Barnstable CJ, Zhang SS, Zhang C, Huang P.

Mol Neurobiol. 2015 Dec;52(3):1364-1377. doi: 10.1007/s12035-014-8945-9. Epub 2014 Oct 25.

PMID:
25344318
15.

Regulation of rod photoreceptor differentiation by STAT3 is controlled by a tyrosine phosphatase.

Pinzon-Guzman C, Xing T, Zhang SS, Barnstable CJ.

J Mol Neurosci. 2015 Jan;55(1):152-159. doi: 10.1007/s12031-014-0397-1. Epub 2014 Aug 10.

16.

Tetrandrine protects mouse retinal ganglion cells from ischemic injury.

Li W, Yang C, Lu J, Huang P, Barnstable CJ, Zhang C, Zhang SS.

Drug Des Devel Ther. 2014 Mar 21;8:327-39. doi: 10.2147/DDDT.S55407. eCollection 2014.

17.

Cell type-specific epigenetic signatures accompany late stages of mouse retina development.

Popova EY, Barnstable CJ, Zhang SS.

Adv Exp Med Biol. 2014;801:3-8. doi: 10.1007/978-1-4614-3209-8_1.

PMID:
24664674
18.

Stat3 mediates LIF-induced protection of astrocytes against toxic ROS by upregulating the UPC2 mRNA pool.

Lapp DW, Zhang SS, Barnstable CJ.

Glia. 2014 Feb;62(2):159-70. doi: 10.1002/glia.22594. Epub 2013 Dec 5.

PMID:
24307565
19.

CD4 positive T helper cells contribute to retinal ganglion cell death in mouse model of ischemia reperfusion injury.

Huang P, Huo Y, Lou LX, Li H, Barnstable CJ, Zhang C, Zhang SS.

Exp Eye Res. 2013 Oct;115:131-9. doi: 10.1016/j.exer.2013.06.015. Epub 2013 Jun 20.

PMID:
23792169
20.

Developmentally regulated linker histone H1c promotes heterochromatin condensation and mediates structural integrity of rod photoreceptors in mouse retina.

Popova EY, Grigoryev SA, Fan Y, Skoultchi AI, Zhang SS, Barnstable CJ.

J Biol Chem. 2013 Jun 14;288(24):17895-907. doi: 10.1074/jbc.M113.452144. Epub 2013 May 3.

21.

Stage and gene specific signatures defined by histones H3K4me2 and H3K27me3 accompany mammalian retina maturation in vivo.

Popova EY, Xu X, DeWan AT, Salzberg AC, Berg A, Hoh J, Zhang SS, Barnstable CJ.

PLoS One. 2012;7(10):e46867. doi: 10.1371/journal.pone.0046867. Epub 2012 Oct 9.

22.

Pigment epithelium-derived factor (PEDF) peptide eye drops reduce inflammation, cell death and vascular leakage in diabetic retinopathy in Ins2(Akita) mice.

Liu Y, Leo LF, McGregor C, Grivitishvili A, Barnstable CJ, Tombran-Tink J.

Mol Med. 2012 Dec 20;18:1387-401. doi: 10.2119/molmed.2012.00008.

23.

Specific protein kinase C isoforms are required for rod photoreceptor differentiation.

Pinzon-Guzman C, Zhang SS, Barnstable CJ.

J Neurosci. 2011 Dec 14;31(50):18606-17. doi: 10.1523/JNEUROSCI.2578-11.2011.

24.

Epigenetics rules.

Popova E, Barnstable CJ.

J Ocul Biol Dis Infor. 2012 Jun 14;4(3):93-4. doi: 10.1007/s12177-012-9088-8. Print 2011 Sep. No abstract available.

25.

[Purified mouse retinal ganglion cell culture].

Huang P, Zhang C, Wang W, Zhang SM, Barnstable CJ.

Zhonghua Yan Ke Za Zhi. 2011 Feb;47(2):129-33. Chinese.

PMID:
21426842
26.

MAPK signaling during Müller glial cell development in retina explant cultures.

Zhang SS, Li H, Huang P, Lou LX, Fu XY, Barnstable CJ.

J Ocul Biol Dis Infor. 2010 Dec;3(4):129-33. doi: 10.1007/s12177-011-9064-8. Epub 2011 Aug 12.

27.

Protein kinase C regulates rod photoreceptor differentiation through modulation of STAT3 signaling.

Pinzon-Guzman C, Shaomin Zhang S, Barnstable CJ.

Adv Exp Med Biol. 2010;664:21-8. doi: 10.1007/978-1-4419-1399-9_3.

PMID:
20237998
28.

Comparison of gene expression during in vivo and in vitro postnatal retina development.

Liu MG, Li H, Xu X, Barnstable CJ, Zhang SS.

J Ocul Biol Dis Infor. 2008 Dec;1(2-4):59-72. doi: 10.1007/s12177-008-9009-z. Epub 2008 Jul 11.

29.

Mitochondria and the regulation of free radical damage in the eye.

Barnstable CJ.

J Ocul Biol Dis Infor. 2009 Sep;2(3):145-148. Epub 2009 Sep 18.

30.

Bacterial endotoxin activates retinal pigment epithelial cells and induces their degeneration through IL-6 and IL-8 autocrine signaling.

Leung KW, Barnstable CJ, Tombran-Tink J.

Mol Immunol. 2009 Apr;46(7):1374-86. doi: 10.1016/j.molimm.2008.12.001. Epub 2009 Jan 20.

PMID:
19157552
31.

STAT3 activation protects retinal ganglion cell layer neurons in response to stress.

Zhang C, Li H, Liu MG, Kawasaki A, Fu XY, Barnstable CJ, Shao-Min Zhang S.

Exp Eye Res. 2008 Jun;86(6):991-7. doi: 10.1016/j.exer.2008.03.020. Epub 2008 Apr 8.

PMID:
18471811
32.

Expression of ZnT and ZIP zinc transporters in the human RPE and their regulation by neurotrophic factors.

Leung KW, Liu M, Xu X, Seiler MJ, Barnstable CJ, Tombran-Tink J.

Invest Ophthalmol Vis Sci. 2008 Mar;49(3):1221-31. doi: 10.1167/iovs.07-0781. Erratum in: Invest Ophthalmol Vis Sci. 2008 Sep;49(9):3811.

PMID:
18326752
33.

Space flight environment induces degeneration in the retina of rat neonates.

Tombran-Tink J, Barnstable CJ.

Adv Exp Med Biol. 2006;572:417-24. No abstract available.

PMID:
17249605
34.

Molecular mechanisms of neuroprotection in the eye.

Barnstable CJ, Tombran-Tink J.

Adv Exp Med Biol. 2006;572:291-5. Review. No abstract available.

PMID:
17249586
35.

A biphasic pattern of gene expression during mouse retina development.

Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY.

BMC Dev Biol. 2006 Oct 17;6:48.

36.
37.

PEDF induces apoptosis in human endothelial cells by activating p38 MAP kinase dependent cleavage of multiple caspases.

Chen L, Zhang SS, Barnstable CJ, Tombran-Tink J.

Biochem Biophys Res Commun. 2006 Oct 6;348(4):1288-95. Epub 2006 Aug 7.

PMID:
16919597
38.

A PEDF N-terminal peptide protects the retina from ischemic injury when delivered in PLGA nanospheres.

Li H, Tran VV, Hu Y, Mark Saltzman W, Barnstable CJ, Tombran-Tink J.

Exp Eye Res. 2006 Oct;83(4):824-33. Epub 2006 Jul 5.

PMID:
16822505
39.

Space shuttle flight environment induces degeneration in the retina of rat neonates.

Tombran-Tink J, Barnstable CJ.

Gravit Space Biol Bull. 2005 Jun;18(2):97-8. No abstract available.

PMID:
16044625
40.

PEDF and the serpins: phylogeny, sequence conservation, and functional domains.

Tombran-Tink J, Aparicio S, Xu X, Tink AR, Lara N, Sawant S, Barnstable CJ, Zhang SS.

J Struct Biol. 2005 Aug;151(2):130-50.

PMID:
16040252
41.

STAT3 activation in response to growth factors or cytokines participates in retina precursor proliferation.

Zhang SS, Liu MG, Kano A, Zhang C, Fu XY, Barnstable CJ.

Exp Eye Res. 2005 Jul;81(1):103-15.

PMID:
15978261
42.

Comprehensive in silico functional specification of mouse retina transcripts.

Zhang SS, Xu X, Li J, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY.

BMC Genomics. 2005 Mar 18;6:40.

43.

Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease.

Andrews ZB, Horvath B, Barnstable CJ, Elsworth J, Yang L, Beal MF, Roth RH, Matthews RT, Horvath TL.

J Neurosci. 2005 Jan 5;25(1):184-91. Erratum in: J Neurosci. 2005 Feb 23;25(8):table of contents.

44.

Expression of angiogenesis factors in human umbilical vein endothelial cells and their regulation by PEDF.

Aparicio S, Sawant S, Lara N, Barnstable CJ, Tombran-Tink J.

Biochem Biophys Res Commun. 2005 Jan 14;326(2):387-94.

PMID:
15582590
45.

Regulation of factors controlling angiogenesis in liver development: a role for PEDF in the formation and maintenance of normal vasculature.

Sawant S, Aparicio S, Tink AR, Lara N, Barnstable CJ, Tombran-Tink J.

Biochem Biophys Res Commun. 2004 Dec 10;325(2):408-13.

PMID:
15530407
46.

Modulation of synaptic function by cGMP and cGMP-gated cation channels.

Barnstable CJ, Wei JY, Han MH.

Neurochem Int. 2004 Nov;45(6):875-84. Review.

PMID:
15312982
47.

Neuroprotective and antiangiogenic actions of PEDF in the eye: molecular targets and therapeutic potential.

Barnstable CJ, Tombran-Tink J.

Prog Retin Eye Res. 2004 Sep;23(5):561-77. Review.

PMID:
15302351
48.

STAT3-mediated signaling in the determination of rod photoreceptor cell fate in mouse retina.

Zhang SS, Wei J, Qin H, Zhang L, Xie B, Hui P, Deisseroth A, Barnstable CJ, Fu XY.

Invest Ophthalmol Vis Sci. 2004 Jul;45(7):2407-12.

PMID:
15223824
49.

Mitochondrial uncoupling proteins: regulators of retinal cell death.

Barnstable CJ, Li M, Reddy R, Horvath TL.

Adv Exp Med Biol. 2003;533:269-75. Review. No abstract available.

PMID:
15180273
50.

Retinoic acid and dexamethasone regulate the expression of PEDF in retinal and endothelial cells.

Tombran-Tink J, Lara N, Apricio SE, Potluri P, Gee S, Ma JX, Chader G, Barnstable CJ.

Exp Eye Res. 2004 May;78(5):945-55.

PMID:
15051476

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