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Items: 1 to 50 of 149


HER2-targeted multimodal imaging of anaplastic thyroid cancer.

Wei W, Jiang D, Rosenkrans ZT, Barnhart TE, Engle JW, Luo Q, Cai W.

Am J Cancer Res. 2019 Nov 1;9(11):2413-2427. eCollection 2019.


Establishing Radiolanthanum Chemistry for Targeted Nuclear Medicine Applications.

Aluicio-Sarduy E, Thiele NA, Martin KE, Vaughn BA, Devaraj J, Olson AP, Barnhart TE, Wilson JJ, Boros E, Engle JW.

Chemistry. 2019 Nov 19. doi: 10.1002/chem.201905202. [Epub ahead of print]


A "Missile-Detonation" Strategy to Precisely Supply and Efficiently Amplify Cerenkov Radiation Energy for Cancer Theranostics.

Yu B, Ni D, Rosenkrans ZT, Barnhart TE, Wei H, Ferreira CA, Lan X, Engle JW, He Q, Yu F, Cai W.

Adv Mater. 2019 Dec;31(52):e1904894. doi: 10.1002/adma.201904894. Epub 2019 Nov 11.


Immuno-PET imaging of VEGFR-2 expression in prostate cancer with 89Zr-labeled ramucirumab.

Li M, Jiang D, Barnhart TE, Cao T, Engle JW, Chen W, Cai W.

Am J Cancer Res. 2019 Sep 1;9(9):2037-2046. eCollection 2019.


Improved production of 76Br, 77Br and 80mBr via CoSe cyclotron targets and vertical dry distillation.

Ellison PA, Olson AP, Barnhart TE, Hoffman SLV, Reilly SW, Makvandi M, Bartels JL, Murali D, DeJesus OT, Lapi SE, Bednarz B, Nickles RJ, Mach RH, Engle JW.

Nucl Med Biol. 2019 Sep 5. pii: S0969-8051(19)30162-3. doi: 10.1016/j.nucmedbio.2019.09.001. [Epub ahead of print]


Size-Optimized Ultrasmall Porous Silica Nanoparticles Depict Vasculature-Based Differential Targeting in Triple Negative Breast Cancer.

Goel S, Ferreira CA, Dogra P, Yu B, Kutyreff CJ, Siamof CM, Engle JW, Barnhart TE, Cristini V, Wang Z, Cai W.

Small. 2019 Nov;15(46):e1903747. doi: 10.1002/smll.201903747. Epub 2019 Sep 29.


Aptamer-Conjugated Framework Nucleic Acids for the Repair of Cerebral Ischemia-Reperfusion Injury.

Li S, Jiang D, Rosenkrans ZT, Barnhart TE, Ehlerding EB, Ni D, Engle JW, Cai W.

Nano Lett. 2019 Oct 9;19(10):7334-7341. doi: 10.1021/acs.nanolett.9b02958. Epub 2019 Sep 13.


Ceria Nanoparticles Meet Hepatic Ischemia-Reperfusion Injury: The Perfect Imperfection.

Ni D, Wei H, Chen W, Bao Q, Rosenkrans ZT, Barnhart TE, Ferreira CA, Wang Y, Yao H, Sun T, Jiang D, Li S, Cao T, Liu Z, Engle JW, Hu P, Lan X, Cai W.

Adv Mater. 2019 Oct;31(40):e1902956. doi: 10.1002/adma.201902956. Epub 2019 Aug 16.


Dual-labeled pertuzumab for multimodality image-guided ovarian tumor resection.

Lee HJ, Ehlerding EB, Jiang D, Barnhart TE, Cao T, Wei W, Ferreira CA, Huang P, Engle JW, Cai W.

Am J Cancer Res. 2019 Jul 1;9(7):1454-1468. eCollection 2019.


PET Measures of D1, D2, and DAT Binding Are Associated With Heightened Tactile Responsivity in Rhesus Macaques: Implications for Sensory Processing Disorder.

Schneider ML, Moore CF, Ahlers EO, Barnhart TE, Christian BT, DeJesus OT, Engle JW, Holden JE, Larson JA, Moirano JM, Murali D, Nickles RJ, Resch LM, Converse AK.

Front Integr Neurosci. 2019 Jul 17;13:29. doi: 10.3389/fnint.2019.00029. eCollection 2019.


Production and in vivo PET/CT imaging of the theranostic pair 132/135La.

Aluicio-Sarduy E, Hernandez R, Olson AP, Barnhart TE, Cai W, Ellison PA, Engle JW.

Sci Rep. 2019 Jul 23;9(1):10658. doi: 10.1038/s41598-019-47137-0.


CD146-Targeted Multimodal Image-Guided Photoimmunotherapy of Melanoma.

Wei W, Jiang D, Ehlerding EB, Barnhart TE, Yang Y, Engle JW, Luo QY, Huang P, Cai W.

Adv Sci (Weinh). 2019 Feb 27;6(9):1801237. doi: 10.1002/advs.201801237. eCollection 2019 May 3.


Noninvasive Imaging and Quantification of Radiotherapy-Induced PD-L1 Upregulation with 89Zr-Df-Atezolizumab.

Ehlerding EB, Lee HJ, Barnhart TE, Jiang D, Kang L, McNeel DG, Engle JW, Cai W.

Bioconjug Chem. 2019 May 15;30(5):1434-1441. doi: 10.1021/acs.bioconjchem.9b00178. Epub 2019 Apr 19.


Radiochemical isolation method for the production of 52gMn from natCr for accelerator targets.

Barrett KE, Aluicio-Sarduy E, Olson AP, Kutyreff CJ, Ellison PA, Barnhart TE, Nickles RJ, Engle JW.

Appl Radiat Isot. 2019 Apr;146:99-103. doi: 10.1016/j.apradiso.2019.01.025. Epub 2019 Feb 1.


Molybdenum-based nanoclusters act as antioxidants and ameliorate acute kidney injury in mice.

Ni D, Jiang D, Kutyreff CJ, Lai J, Yan Y, Barnhart TE, Yu B, Im HJ, Kang L, Cho SY, Liu Z, Huang P, Engle JW, Cai W.

Nat Commun. 2018 Dec 21;9(1):5421. doi: 10.1038/s41467-018-07890-8.


General synthesis of silica-based yolk/shell hybrid nanomaterials and in vivo tumor vasculature targeting.

Chen F, Goel S, Shi S, Barnhart TE, Lan X, Cai W.

Nano Res. 2018 Sep;11(9):4890-4904. doi: 10.1007/s12274-018-2078-9. Epub 2018 May 8.


Photo-Enhanced Singlet Oxygen Generation of Prussian Blue-Based Nanocatalyst for Augmented Photodynamic Therapy.

Wang D, Shi R, Zhou J, Shi S, Wu H, Xu P, Wang H, Xia G, Barnhart TE, Cai W, Guo Z, Chen Q.

iScience. 2018 Nov 30;9:14-26. doi: 10.1016/j.isci.2018.10.005. Epub 2018 Oct 12.


Magnetic Targeting of Nanotheranostics Enhances Cerenkov Radiation-Induced Photodynamic Therapy.

Ni D, Ferreira CA, Barnhart TE, Quach V, Yu B, Jiang D, Wei W, Liu H, Engle JW, Hu P, Cai W.

J Am Chem Soc. 2018 Nov 7;140(44):14971-14979. doi: 10.1021/jacs.8b09374. Epub 2018 Oct 29.


Simplified and automatable radiochemical separation strategy for the production of radiopharmaceutical quality 86Y using single column extraction chromatography.

Aluicio-Sarduy E, Hernandez R, Valdovinos HF, Kutyreff CJ, Ellison PA, Barnhart TE, Nickles RJ, Engle JW.

Appl Radiat Isot. 2018 Dec;142:28-31. doi: 10.1016/j.apradiso.2018.09.016. Epub 2018 Sep 14.


In vivo imaging of inflammation and oxidative stress in a nonhuman primate model of cardiac sympathetic neurodegeneration.

Metzger JM, Moore CF, Boettcher CA, Brunner KG, Fleddermann RA, Matsoff HN, Resnikoff HA, Bondarenko V, Kamp TJ, Hacker TA, Barnhart TE, Lao PJ, Christian BT, Nickles RJ, Gallagher CL, Holden JE, Emborg ME.

NPJ Parkinsons Dis. 2018 Jul 13;4:22. doi: 10.1038/s41531-018-0057-1. eCollection 2018.


Evaluation of a chloride-based 89Zr isolation strategy using a tributyl phosphate (TBP)-functionalized extraction resin.

Graves SA, Kutyreff C, Barrett KE, Hernandez R, Ellison PA, Happel S, Aluicio-Sarduy E, Barnhart TE, Nickles RJ, Engle JW.

Nucl Med Biol. 2018 Sep - Oct;64-65:1-7. doi: 10.1016/j.nucmedbio.2018.06.003. Epub 2018 Jun 18.


In Vivo Characterization and Quantification of Neurofibrillary Tau PET Radioligand 18F-MK-6240 in Humans from Alzheimer Disease Dementia to Young Controls.

Betthauser TJ, Cody KA, Zammit MD, Murali D, Converse AK, Barnhart TE, Stone CK, Rowley HA, Johnson SC, Christian BT.

J Nucl Med. 2019 Jan;60(1):93-99. doi: 10.2967/jnumed.118.209650. Epub 2018 May 18.


Radiolabeled polyoxometalate clusters: Kidney dysfunction evaluation and tumor diagnosis by positron emission tomography imaging.

Ni D, Jiang D, Im HJ, Valdovinos HF, Yu B, Goel S, Barnhart TE, Huang P, Cai W.

Biomaterials. 2018 Jul;171:144-152. doi: 10.1016/j.biomaterials.2018.04.019. Epub 2018 Apr 12.


Noninvasive Trafficking of Brentuximab Vedotin and PET Imaging of CD30 in Lung Cancer Murine Models.

Kang L, Jiang D, Ehlerding EB, Barnhart TE, Ni D, Engle JW, Wang R, Huang P, Xu X, Cai W.

Mol Pharm. 2018 Apr 2;15(4):1627-1634. doi: 10.1021/acs.molpharmaceut.7b01168. Epub 2018 Mar 20.


Bacteria-like mesoporous silica-coated gold nanorods for positron emission tomography and photoacoustic imaging-guided chemo-photothermal combined therapy.

Xu C, Chen F, Valdovinos HF, Jiang D, Goel S, Yu B, Sun H, Barnhart TE, Moon JJ, Cai W.

Biomaterials. 2018 May;165:56-65. doi: 10.1016/j.biomaterials.2018.02.043. Epub 2018 Feb 23.


ImmunoPET imaging of CD38 in murine lymphoma models using 89Zr-labeled daratumumab.

Kang L, Jiang D, England CG, Barnhart TE, Yu B, Rosenkrans ZT, Wang R, Engle JW, Xu X, Huang P, Cai W.

Eur J Nucl Med Mol Imaging. 2018 Jul;45(8):1372-1381. doi: 10.1007/s00259-018-3941-3. Epub 2018 Feb 15.


Reassembly of 89 Zr-Labeled Cancer Cell Membranes into Multicompartment Membrane-Derived Liposomes for PET-Trackable Tumor-Targeted Theranostics.

Yu B, Goel S, Ni D, Ellison PA, Siamof CM, Jiang D, Cheng L, Kang L, Yu F, Liu Z, Barnhart TE, He Q, Zhang H, Cai W.

Adv Mater. 2018 Mar;30(13):e1704934. doi: 10.1002/adma.201704934. Epub 2018 Feb 12.


PET radiometals for antibody labeling.

Aluicio-Sarduy E, Ellison PA, Barnhart TE, Cai W, Nickles RJ, Engle JW.

J Labelled Comp Radiopharm. 2018 Jul;61(9):636-651. doi: 10.1002/jlcr.3607. Epub 2018 Mar 12. Review.


Activatable Hybrid Nanotheranostics for Tetramodal Imaging and Synergistic Photothermal/Photodynamic Therapy.

Goel S, Ferreira CA, Chen F, Ellison PA, Siamof CM, Barnhart TE, Cai W.

Adv Mater. 2018 Feb;30(6). doi: 10.1002/adma.201704367. Epub 2017 Dec 21.


Alzheimer-Like Pattern of Hypometabolism Emerges with Elevated Amyloid-β Burden in Down Syndrome.

Lao PJ, Handen BL, Betthauser TJ, Mihaila I, Hartley SL, Cohen AD, Tudorascu DL, Bulova PD, Lopresti BJ, Tumuluru RV, Murali D, Mathis CA, Barnhart TE, Stone CK, Price JC, Devenny DA, Johnson SC, Klunk WE, Christian BT.

J Alzheimers Dis. 2018;61(2):631-644. doi: 10.3233/JAD-170720.


Chelator-Free Labeling of Metal Oxide Nanostructures with Zirconium-89 for Positron Emission Tomography Imaging.

Cheng L, Shen S, Jiang D, Jin Q, Ellison PA, Ehlerding EB, Goel S, Song G, Huang P, Barnhart TE, Liu Z, Cai W.

ACS Nano. 2017 Dec 26;11(12):12193-12201. doi: 10.1021/acsnano.7b05428. Epub 2017 Nov 29.


Renal-Clearable PEGylated Porphyrin Nanoparticles for Image-guided Photodynamic Cancer Therapy.

Cheng L, Jiang D, Kamkaew A, Valdovinos HF, Im HJ, Feng L, England CG, Goel S, Barnhart TE, Liu Z, Cai W.

Adv Funct Mater. 2017 Sep 13;27(34). pii: 1702928. doi: 10.1002/adfm.201702928. Epub 2017 Jul 26.


Characterization of the radiosynthesis and purification of [18F]THK-5351, a PET ligand for neurofibrillary tau.

Betthauser TJ, Ellison PA, Murali D, Lao PJ, Barnhart TE, Furumoto S, Okamura N, Johnson SC, Engle JW, Nickles RJ, Christian BT.

Appl Radiat Isot. 2017 Dec;130:230-237. doi: 10.1016/j.apradiso.2017.10.002. Epub 2017 Oct 4.


Cyclotron production and radiochemical separation of 55Co and 58mCo from 54Fe, 58Ni and 57Fe targets.

Valdovinos HF, Hernandez R, Graves S, Ellison PA, Barnhart TE, Theuer CP, Engle JW, Cai W, Nickles RJ.

Appl Radiat Isot. 2017 Dec;130:90-101. doi: 10.1016/j.apradiso.2017.09.005. Epub 2017 Sep 6.


ImmunoPET imaging of tissue factor expression in pancreatic cancer with 89Zr-Df-ALT-836.

Hernandez R, England CG, Yang Y, Valdovinos HF, Liu B, Wong HC, Barnhart TE, Cai W.

J Control Release. 2017 Oct 28;264:160-168. doi: 10.1016/j.jconrel.2017.08.029. Epub 2017 Aug 24.


89Zr-labeled nivolumab for imaging of T-cell infiltration in a humanized murine model of lung cancer.

England CG, Jiang D, Ehlerding EB, Rekoske BT, Ellison PA, Hernandez R, Barnhart TE, McNeel DG, Huang P, Cai W.

Eur J Nucl Med Mol Imaging. 2018 Jan;45(1):110-120. doi: 10.1007/s00259-017-3803-4. Epub 2017 Aug 19.


A tumor-targeted polymer theranostics platform for positron emission tomography and fluorescence imaging.

Koziolová E, Goel S, Chytil P, Janoušková O, Barnhart TE, Cai W, Etrych T.

Nanoscale. 2017 Aug 3;9(30):10906-10918. doi: 10.1039/c7nr03306k.


Longitudinal changes in amyloid positron emission tomography and volumetric magnetic resonance imaging in the nondemented Down syndrome population.

Lao PJ, Handen BL, Betthauser TJ, Mihaila I, Hartley SL, Cohen AD, Tudorascu DL, Bulova PD, Lopresti BJ, Tumuluru RV, Murali D, Mathis CA, Barnhart TE, Stone CK, Price JC, Devenny DA, Mailick MR, Klunk WE, Johnson SC, Christian BT.

Alzheimers Dement (Amst). 2017 May 23;9:1-9. doi: 10.1016/j.dadm.2017.05.001. eCollection 2017.


Preparation and in vivo characterization of 51MnCl2 as PET tracer of Ca2+ channel-mediated transport.

Graves SA, Hernandez R, Valdovinos HF, Ellison PA, Engle JW, Barnhart TE, Cai W, Nickles RJ.

Sci Rep. 2017 Jun 8;7(1):3033. doi: 10.1038/s41598-017-03202-0.


CD38 as a PET Imaging Target in Lung Cancer.

Ehlerding EB, England CG, Jiang D, Graves SA, Kang L, Lacognata S, Barnhart TE, Cai W.

Mol Pharm. 2017 Jul 3;14(7):2400-2406. doi: 10.1021/acs.molpharmaceut.7b00298. Epub 2017 Jun 8.


Radiomanganese PET Detects Changes in Functional β-Cell Mass in Mouse Models of Diabetes.

Hernandez R, Graves SA, Gregg T, VanDeusen HR, Fenske RJ, Wienkes HN, England CG, Valdovinos HF, Jeffery JJ, Barnhart TE, Severin GW, Nickles RJ, Kimple ME, Merrins MJ, Cai W.

Diabetes. 2017 Aug;66(8):2163-2174. doi: 10.2337/db16-1285. Epub 2017 May 17.


[18 F]Nifene test-retest reproducibility in first-in-human imaging of α4β2* nicotinic acetylcholine receptors.

Lao PJ, Betthauser TJ, Tudorascu DL, Barnhart TE, Hillmer AT, Stone CK, Mukherjee J, Christian BT.

Synapse. 2017 Aug;71(8). doi: 10.1002/syn.21981. Epub 2017 Apr 26.


Bioresponsive Polyoxometalate Cluster for Redox-Activated Photoacoustic Imaging-Guided Photothermal Cancer Therapy.

Ni D, Jiang D, Valdovinos HF, Ehlerding EB, Yu B, Barnhart TE, Huang P, Cai W.

Nano Lett. 2017 May 10;17(5):3282-3289. doi: 10.1021/acs.nanolett.7b00995. Epub 2017 Apr 20.


Intrinsic radiolabeling of Titanium-45 using mesoporous silica nanoparticles.

Chen F, Valdovinos HF, Hernandez R, Goel S, Barnhart TE, Cai W.

Acta Pharmacol Sin. 2017 Jun;38(6):907-913. doi: 10.1038/aps.2017.1. Epub 2017 Apr 17.


Nuclear excitation functions of proton-induced reactions (Ep = 35 - 90 MeV) from Fe, Cu, and Al.

Graves SA, Ellison PA, Barnhart TE, Valdovinos HF, Birnbaum ER, Nortier FM, Nickles RJ, Engle JW.

Nucl Instrum Methods Phys Res B. 2016 Nov 1;386:44-53. doi: 10.1016/j.nimb.2016.09.018. Epub 2016 Sep 28.


Intrinsic and Stable Conjugation of Thiolated Mesoporous Silica Nanoparticles with Radioarsenic.

Ellison PA, Chen F, Goel S, Barnhart TE, Nickles RJ, DeJesus OT, Cai W.

ACS Appl Mater Interfaces. 2017 Mar 1;9(8):6772-6781. doi: 10.1021/acsami.6b14049. Epub 2017 Feb 16.


Intrinsically 89Zr-labeled Gd2O2S:Eu nanophosphors with high in vivo stability for dual-modality imaging.

Ai F, Goel S, Zhan Y, Valdovinos HF, Chen F, Barnhart TE, Cai W.

Am J Transl Res. 2016 Dec 15;8(12):5591-5600. eCollection 2016.


Theranostic Liposomes with Hypoxia-Activated Prodrug to Effectively Destruct Hypoxic Tumors Post-Photodynamic Therapy.

Feng L, Cheng L, Dong Z, Tao D, Barnhart TE, Cai W, Chen M, Liu Z.

ACS Nano. 2017 Jan 24;11(1):927-937. doi: 10.1021/acsnano.6b07525. Epub 2016 Dec 29.


Engineering Intrinsically Zirconium-89 Radiolabeled Self-Destructing Mesoporous Silica Nanostructures for In Vivo Biodistribution and Tumor Targeting Studies.

Goel S, Chen F, Luan S, Valdovinos HF, Shi S, Graves SA, Ai F, Barnhart TE, Theuer CP, Cai W.

Adv Sci (Weinh). 2016 May 27;3(11):1600122. eCollection 2016 Nov.


In Vivo Comparison of Tau Radioligands 18F-THK-5351 and 18F-THK-5317.

Betthauser TJ, Lao PJ, Murali D, Barnhart TE, Furumoto S, Okamura N, Stone CK, Johnson SC, Christian BT.

J Nucl Med. 2017 Jun;58(6):996-1002. doi: 10.2967/jnumed.116.182980. Epub 2016 Nov 10.

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