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Items: 1 to 50 of 1523

1.

Ezrin, a Membrane Cytoskeleton Cross Linker Protein, as a Marker of Epithelial Damage in Asthma.

Jia M, Yan X, Jiang X, Wu Y, Xu J, Meng Y, Yang Y, Shan X, Zhang X, Mao S, Gu W, Pavlidis S, Barnes PJ, Adcock IM, Huang M, Yao X.

Am J Respir Crit Care Med. 2018 Oct 5. doi: 10.1164/rccm.201802-0373OC. [Epub ahead of print]

PMID:
30290132
2.

Comparison of fluticasone propionate and budesonide on COPD macrophage and neutrophil function.

Belchamber KB, Thomas CM, Dunne AE, Barnes PJ, Donnelly LE.

Int J Chron Obstruct Pulmon Dis. 2018 Sep 17;13:2883-2897. doi: 10.2147/COPD.S169337. eCollection 2018.

3.

Correction: Suppression of GATA-3 Nuclear Import and Phosphorylation: A Novel Mechanism of Corticosteroid Action in Allergic Disease.

Maneechotesuwan K, Yao X, Ito K, Jazrawi E, Usmani OS, Adcock IM, Barnes PJ.

PLoS Med. 2018 Sep 7;15(9):e1002657. doi: 10.1371/journal.pmed.1002657. eCollection 2018 Sep.

4.

MicroRNA-570 is a novel regulator of cellular senescence and inflammaging.

Baker JR, Vuppusetty C, Colley T, Hassibi S, Fenwick PS, Donnelly LE, Ito K, Barnes PJ.

FASEB J. 2018 Aug 29:fj201800965R. doi: 10.1096/fj.201800965R. [Epub ahead of print]

PMID:
30156909
5.

Quantitative Screening Method for Erythromycin and Tylosin in Honey Using RapidFire Mass Spectrometry.

Veach BT, Mudalige TK, Barnes PJ, Baker CA.

J AOAC Int. 2018 Jul 31. doi: 10.5740/jaoacint.18-0107. [Epub ahead of print]

PMID:
30064549
6.

Adenosine 5'-triphosphate's role in bradycardia and syncope associated with pulmonary embolism.

Pelleg A, Schulman ES, Barnes PJ.

Respir Res. 2018 Jul 28;19(1):142. doi: 10.1186/s12931-018-0848-2.

7.

Pre-clinical Pharmacokinetic and Metabolomic Analyses of Isorhapontigenin, a Dietary Resveratrol Derivative.

Dai Y, Yeo SCM, Barnes PJ, Donnelly LE, Loo LC, Lin HS.

Front Pharmacol. 2018 Jul 11;9:753. doi: 10.3389/fphar.2018.00753. eCollection 2018.

8.

Impact of Detection Method and Age on Survival Outcomes in Triple-Negative Breast Cancer: A Population-Based Cohort Analysis.

Rayson D, Payne JI, Michael JCR, Tsuruda KM, Abdolell M, Barnes PJ.

Clin Breast Cancer. 2018 Oct;18(5):e955-e960. doi: 10.1016/j.clbc.2018.04.013. Epub 2018 Apr 28.

PMID:
29885790
9.

Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.

O'Byrne PM, FitzGerald JM, Bateman ED, Barnes PJ, Zhong N, Keen C, Jorup C, Lamarca R, Ivanov S, Reddel HK.

N Engl J Med. 2018 May 17;378(20):1865-1876. doi: 10.1056/NEJMoa1715274.

PMID:
29768149
10.

As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.

Bateman ED, Reddel HK, O'Byrne PM, Barnes PJ, Zhong N, Keen C, Jorup C, Lamarca R, Siwek-Posluszna A, FitzGerald JM.

N Engl J Med. 2018 May 17;378(20):1877-1887. doi: 10.1056/NEJMoa1715275.

PMID:
29768147
11.

Efficacy and safety profile of xanthines in COPD: a network meta-analysis.

Cazzola M, Calzetta L, Barnes PJ, Criner GJ, Martinez FJ, Papi A, Gabriella Matera M.

Eur Respir Rev. 2018 May 2;27(148). pii: 180010. doi: 10.1183/16000617.0010-2018. Print 2018 Jun 30. Review.

12.

Breathomics for Assessing the Effects of Treatment and Withdrawal With Inhaled Beclomethasone/Formoterol in Patients With COPD.

Montuschi P, Santini G, Mores N, Vignoli A, Macagno F, Shoreh R, Tenori L, Zini G, Fuso L, Mondino C, Di Natale C, D'Amico A, Luchinat C, Barnes PJ, Higenbottam T.

Front Pharmacol. 2018 Apr 17;9:258. doi: 10.3389/fphar.2018.00258. eCollection 2018.

13.

Pharmacological treatment of COPD: the devil is always in the detail.

Singh D, Barnes PJ, Stockley R, Lopez Valera MV, Vogelmeier C, Agusti A.

Eur Respir J. 2018 Apr 19;51(4). pii: 1800263. doi: 10.1183/13993003.00263-2018. Print 2018 Apr. No abstract available.

PMID:
29674480
14.

Targeting cytokines to treat asthma and chronic obstructive pulmonary disease.

Barnes PJ.

Nat Rev Immunol. 2018 Jul;18(7):454-466. doi: 10.1038/s41577-018-0006-6. Review.

PMID:
29626211
15.

Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease Is Enhanced by Nrf2 Agonists.

Bewley MA, Budd RC, Ryan E, Cole J, Collini P, Marshall J, Kolsum U, Beech G, Emes RD, Tcherniaeva I, Berbers GAM, Walmsley SR, Donaldson G, Wedzicha JA, Kilty I, Rumsey W, Sanchez Y, Brightling CE, Donnelly LE, Barnes PJ, Singh D, Whyte MKB, Dockrell DH; COPDMAP.

Am J Respir Crit Care Med. 2018 Sep 15;198(6):739-750. doi: 10.1164/rccm.201705-0903OC.

PMID:
29547002
16.

The dynamic shuttling of SIRT1 between cytoplasm and nuclei in bronchial epithelial cells by single and repeated cigarette smoke exposure.

Yanagisawa S, Baker JR, Vuppusetty C, Koga T, Colley T, Fenwick P, Donnelly LE, Barnes PJ, Ito K.

PLoS One. 2018 Mar 6;13(3):e0193921. doi: 10.1371/journal.pone.0193921. eCollection 2018.

17.

Reduced Clearance of Fungal Spores by Chronic Obstructive Pulmonary Disease GM-CSF- and M-CSF-derived Macrophages.

Wrench C, Belchamber KBR, Bercusson A, Shah A, Barnes PJ, Armstrong-James D, Donnelly LE.

Am J Respir Cell Mol Biol. 2018 Feb;58(2):271-273. doi: 10.1165/rcmb.2017-0351LE. No abstract available.

PMID:
29388829
18.

Role of airway glucose in bacterial infections in patients with chronic obstructive pulmonary disease.

Mallia P, Webber J, Gill SK, Trujillo-Torralbo MB, Calderazzo MA, Finney L, Bakhsoliani E, Farne H, Singanayagam A, Footitt J, Hewitt R, Kebadze T, Aniscenko J, Padmanaban V, Molyneaux PL, Adcock IM, Barnes PJ, Ito K, Elkin SL, Kon OM, Cookson WO, Moffat MF, Johnston SL, Tregoning JS.

J Allergy Clin Immunol. 2018 Sep;142(3):815-823.e6. doi: 10.1016/j.jaci.2017.10.017. Epub 2018 Jan 5.

19.

ERS/ATS workshop report on respiratory health effects of household air pollution.

Sood A, Assad NA, Barnes PJ, Churg A, Gordon SB, Harrod KS, Irshad H, Kurmi OP, Martin WJ 2nd, Meek P, Mortimer K, Noonan CW, Perez-Padilla R, Smith KR, Tesfaigzi Y, Ward T, Balmes J.

Eur Respir J. 2018 Jan 4;51(1). pii: 1700698. doi: 10.1183/13993003.00698-2017. Print 2018 Jan.

PMID:
29301918
20.

TGF-β Signaling Pathways in Different Compartments of the Lower Airways of Patients With Stable COPD.

Di Stefano A, Sangiorgi C, Gnemmi I, Casolari P, Brun P, Ricciardolo FLM, Contoli M, Papi A, Maniscalco P, Ruggeri P, Girbino G, Cappello F, Pavlides S, Guo Y, Chung KF, Barnes PJ, Adcock IM, Balbi B, Caramori G.

Chest. 2018 Apr;153(4):851-862. doi: 10.1016/j.chest.2017.12.017. Epub 2017 Dec 28.

21.

Sputum microbiome temporal variability and dysbiosis in chronic obstructive pulmonary disease exacerbations: an analysis of the COPDMAP study.

Wang Z, Singh R, Miller BE, Tal-Singer R, Van Horn S, Tomsho L, Mackay A, Allinson JP, Webb AJ, Brookes AJ, George LM, Barker B, Kolsum U, Donnelly LE, Belchamber K, Barnes PJ, Singh D, Brightling CE, Donaldson GC, Wedzicha JA, Brown JR; COPDMAP.

Thorax. 2018 Apr;73(4):331-338. doi: 10.1136/thoraxjnl-2017-210741. Epub 2017 Dec 21.

22.

Quercetin restores corticosteroid sensitivity in cells from patients with chronic obstructive pulmonary disease.

Mitani A, Azam A, Vuppusetty C, Ito K, Mercado N, Barnes PJ.

Exp Lung Res. 2017 Nov - Dec;43(9-10):417-425. doi: 10.1080/01902148.2017.1393707. Epub 2017 Dec 11.

23.

Corticosteroid plus β2-agonist in a single inhaler as reliever therapy in intermittent and mild asthma: a proof-of-concept systematic review and meta-analysis.

Wang G, Zhang X, Zhang HP, Wang L, Kang Y, Barnes PJ, Wang G.

Respir Res. 2017 Dec 6;18(1):203. doi: 10.1186/s12931-017-0687-6. Review.

24.

Quantitation and Confirmation of Chloramphenicol, Florfenicol, and Nitrofuran Metabolites in Honey Using LC-MS/MS.

Veach BT, Anglin R, Mudalige TK, Barnes PJ.

J AOAC Int. 2018 May 1;101(3):897-904. doi: 10.5740/jaoacint.17-0262. Epub 2017 Nov 30.

PMID:
29187264
25.

Budesonide facilitates weaning from mechanical ventilation in difficult-to-wean very severe COPD patients: Association with inflammatory mediators and cells.

Hashemian SM, Mortaz E, Jamaati H, Bagheri L, Mohajerani SA, Garssen J, Movassaghi M, Barnes PJ, Hill NS, Adcock IM.

J Crit Care. 2018 Apr;44:161-167. doi: 10.1016/j.jcrc.2017.10.045. Epub 2017 Oct 31.

PMID:
29127842
26.

Mitochondria, telomeres and cell senescence: Implications for lung ageing and disease.

Birch J, Barnes PJ, Passos JF.

Pharmacol Ther. 2018 Mar;183:34-49. doi: 10.1016/j.pharmthera.2017.10.005. Epub 2017 Oct 4. Review.

27.

Downregulation of MicroRNA-126 Augments DNA Damage Response in Cigarette Smokers and Patients with Chronic Obstructive Pulmonary Disease.

Paschalaki KE, Zampetaki A, Baker JR, Birrell MA, Starke RD, Belvisi MG, Donnelly LE, Mayr M, Randi AM, Barnes PJ.

Am J Respir Crit Care Med. 2018 Mar 1;197(5):665-668. doi: 10.1164/rccm.201706-1304LE. No abstract available.

28.

Effects of an Airway Clearance Device on Inflammation, Bacteriology, and Mucus Transport in Bronchiectasis.

Tambascio J, de Souza HCD, Martinez R, Baddini-Martinez JA, Barnes PJ, Gastaldi AC.

Respir Care. 2017 Aug;62(8):1067-1074. doi: 10.4187/respcare.05214.

29.

Erratum to "Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary" [Arch Bronconeumol. 2017;53:128-49].

Vogelmeier CF, Criner GJ, Martínez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DMG, Varela MVL, Nishimura M, Roche N, Rodríguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agustí A.

Arch Bronconeumol. 2017 Jul;53(7):411-412. doi: 10.1016/j.arbres.2017.06.001. English, Spanish. No abstract available.

30.

Cellular and molecular mechanisms of asthma and COPD.

Barnes PJ.

Clin Sci (Lond). 2017 Jul 1;131(13):1541-1558. doi: 10.1042/CS20160487. Review.

31.

Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages.

Bewley MA, Preston JA, Mohasin M, Marriott HM, Budd RC, Swales J, Collini P, Greaves DR, Craig RW, Brightling CE, Donnelly LE, Barnes PJ, Singh D, Shapiro SD, Whyte MKB, Dockrell DH.

Am J Respir Crit Care Med. 2017 Oct 1;196(7):845-855. doi: 10.1164/rccm.201608-1714OC.

32.

Bronchial inflammation and bacterial load in stable COPD is associated with TLR4 overexpression.

Di Stefano A, Ricciardolo FLM, Caramori G, Adcock IM, Chung KF, Barnes PJ, Brun P, Leonardi A, Andò F, Vallese D, Gnemmi I, Righi L, Cappello F, Balbi B.

Eur Respir J. 2017 May 23;49(5). pii: 1602006. doi: 10.1183/13993003.02006-2016. Print 2017 May.

PMID:
28536249
33.

Reduced HDAC2 in skeletal muscle of COPD patients.

To M, Swallow EB, Akashi K, Haruki K, Natanek SA, Polkey MI, Ito K, Barnes PJ.

Respir Res. 2017 May 19;18(1):99. doi: 10.1186/s12931-017-0588-8.

34.

Decreased phosphatase PTEN amplifies PI3K signaling and enhances proinflammatory cytokine release in COPD.

Yanagisawa S, Baker JR, Vuppusetty C, Fenwick P, Donnelly LE, Ito K, Barnes PJ.

Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L230-L239. doi: 10.1152/ajplung.00382.2016. Epub 2017 May 18.

35.

Decreased Serum Sirtuin-1 in COPD.

Yanagisawa S, Papaioannou AI, Papaporfyriou A, Baker JR, Vuppusetty C, Loukides S, Barnes PJ, Ito K.

Chest. 2017 Aug;152(2):343-352. doi: 10.1016/j.chest.2017.05.004. Epub 2017 May 12.

36.

A European Respiratory Society technical standard: exhaled biomarkers in lung disease.

Horváth I, Barnes PJ, Loukides S, Sterk PJ, Högman M, Olin AC, Amann A, Antus B, Baraldi E, Bikov A, Boots AW, Bos LD, Brinkman P, Bucca C, Carpagnano GE, Corradi M, Cristescu S, de Jongste JC, Dinh-Xuan AT, Dompeling E, Fens N, Fowler S, Hohlfeld JM, Holz O, Jöbsis Q, Van De Kant K, Knobel HH, Kostikas K, Lehtimäki L, Lundberg J, Montuschi P, Van Muylem A, Pennazza G, Reinhold P, Ricciardolo FLM, Rosias P, Santonico M, van der Schee MP, van Schooten FJ, Spanevello A, Tonia T, Vink TJ.

Eur Respir J. 2017 Apr 26;49(4). pii: 1600965. doi: 10.1183/13993003.00965-2016. Print 2017 Apr.

PMID:
28446552
37.

Contrasting effects of ATP and adenosine on capsaicin challenge in asthmatic patients.

Basoglu OK, Pelleg A, Kharitonov SA, Barnes PJ.

Pulm Pharmacol Ther. 2017 Aug;45:13-18. doi: 10.1016/j.pupt.2017.04.004. Epub 2017 Apr 6.

38.

Increased neutrophil gelatinase-associated lipocalin (NGAL) promotes airway remodelling in chronic obstructive pulmonary disease.

Wang Y, Jia M, Yan X, Cao L, Barnes PJ, Adcock IM, Huang M, Yao X.

Clin Sci (Lond). 2017 May 22;131(11):1147-1159. doi: 10.1042/CS20170096. Print 2017 Jun 1.

39.

Isorhapontigenin, a bioavailable dietary polyphenol, suppresses airway epithelial cell inflammation through a corticosteroid-independent mechanism.

Yeo SCM, Fenwick PS, Barnes PJ, Lin HS, Donnelly LE.

Br J Pharmacol. 2017 Jul;174(13):2043-2059. doi: 10.1111/bph.13803. Epub 2017 May 16.

40.

Prolactin/androgen-inducible carboxypeptidase-D increases with nitrotyrosine and Ki67 for breast cancer progression in vivo, and upregulates progression markers VEGF-C and Runx2 in vitro.

Thomas LN, Chedrawe ER, Barnes PJ, Too CKL.

Breast Cancer Res Treat. 2017 Jul;164(1):27-40. doi: 10.1007/s10549-017-4223-7. Epub 2017 Mar 31.

PMID:
28364216
41.

A Randomized Pragmatic Trial of Changing to and Stepping Down Fluticasone/Formoterol in Asthma.

Usmani OS, Kemppinen A, Gardener E, Thomas V, Konduru PR, Callan C, McLoughlin A, Woodhead V, Brady A, Juniper EF, Barnes PJ, Price D.

J Allergy Clin Immunol Pract. 2017 Sep - Oct;5(5):1378-1387.e5. doi: 10.1016/j.jaip.2017.02.006. Epub 2017 Mar 25.

42.

BET proteins are a key component of immunoglobulin gene expression.

Shim JM, Lee JS, Russell KE, Wiegman CH, Barnes PJ, Fear D, Adcock IM, Durham AL.

Epigenomics. 2017 Apr;9(4):393-406. doi: 10.2217/epi-2016-0147. Epub 2017 Mar 21.

43.

Impaired Dual-Specificity Protein Phosphatase DUSP4 Reduces Corticosteroid Sensitivity.

Kobayashi Y, Ito K, Kanda A, Tomoda K, Mercado N, Barnes PJ.

Mol Pharmacol. 2017 May;91(5):475-481. doi: 10.1124/mol.116.107656. Epub 2017 Mar 10.

44.

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary.

Vogelmeier CF, Criner GJ, Martínez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, López Varela MV, Nishimura M, Roche N, Rodríguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agustí A.

Arch Bronconeumol. 2017 Mar;53(3):128-149. doi: 10.1016/j.arbres.2017.02.001. Epub 2017 Mar 6. English, Spanish. Erratum in: Arch Bronconeumol. 2017 Jul;53(7):411-412.

45.

GOLD 2017: A New Report.

Barnes PJ.

Chest. 2017 Feb;151(2):245-246. doi: 10.1016/j.chest.2016.11.042. No abstract available.

PMID:
28183480
46.

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary.

Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, López Varela MV, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agusti A.

Eur Respir J. 2017 Mar 6;49(3). pii: 1700214. doi: 10.1183/13993003.00214-2017. Print 2017 Mar. Erratum in: Eur Respir J. 2017 Jun 22;49(6):.

47.

Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary.

Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, López Varela MV, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agusti A.

Respirology. 2017 Apr;22(3):575-601. doi: 10.1111/resp.13012. Epub 2017 Mar 7.

48.

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary.

Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, López Varela MV, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agustí A.

Am J Respir Crit Care Med. 2017 Mar 1;195(5):557-582. doi: 10.1164/rccm.201701-0218PP.

49.

Professor Neil Pride.

Barnes PJ, Hughes M.

Thorax. 2017 Mar;72(3):292-293. doi: 10.1136/thoraxjnl-2016-209834. Epub 2017 Jan 11. No abstract available.

PMID:
28077612
50.

The SYGMA programme of phase 3 trials to evaluate the efficacy and safety of budesonide/formoterol given 'as needed' in mild asthma: study protocols for two randomised controlled trials.

O'Byrne PM, FitzGerald JM, Zhong N, Bateman E, Barnes PJ, Keen C, Almqvist G, Pemberton K, Jorup C, Ivanov S, Reddel HK.

Trials. 2017 Jan 10;18(1):12. doi: 10.1186/s13063-016-1731-4.

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