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Items: 1 to 50 of 142

1.

Risk factors for exacerbations and pneumonia in patients with chronic obstructive pulmonary disease: a pooled analysis.

Hartley BF, Barnes NC, Lettis S, Compton CH, Papi A, Jones P.

Respir Res. 2020 Jan 6;21(1):5. doi: 10.1186/s12931-019-1262-0.

2.

Chronic Obstructive Pulmonary Disease as a Predictor of Cardiovascular Risk: A Case-Control Study.

Khanji MY, Stone IS, Boubertakh R, Cooper JA, Barnes NC, Petersen SE.

COPD. 2020 Feb;17(1):81-89. doi: 10.1080/15412555.2019.1694501. Epub 2019 Dec 13.

PMID:
31833441
3.

Inhaled corticosteroids, blood eosinophils, and FEV1 decline in patients with COPD in a large UK primary health care setting.

Whittaker HR, Müllerova H, Jarvis D, Barnes NC, Jones PW, Compton CH, Kiddle SJ, Quint JK.

Int J Chron Obstruct Pulmon Dis. 2019 May 23;14:1063-1073. doi: 10.2147/COPD.S200919. eCollection 2019.

4.

Blood eosinophils: a biomarker of COPD exacerbation reduction with inhaled corticosteroids.

Siddiqui SH, Pavord ID, Barnes NC, Guasconi A, Lettis S, Pascoe S, Petruzzelli S.

Int J Chron Obstruct Pulmon Dis. 2018 Nov 6;13:3669-3676. doi: 10.2147/COPD.S179425. eCollection 2018.

5.

Detection of virus-specific polymeric immunoglobulin A in acute hepatitis A, C, E virus serum samples using novel chimeric secretory component.

Mohd Hanafiah K, Garcia ML, Barnes NC, Anderson DA.

BMC Res Notes. 2018 Oct 1;11(1):688. doi: 10.1186/s13104-018-3799-2.

6.

Vitamin D receptor genotype influences risk of upper respiratory infection.

Jolliffe DA, Greiller CL, Mein CA, Hoti M, Bakhsoliani E, Telcian AG, Simpson A, Barnes NC, Curtin JA, Custovic A, Johnston SL, Griffiths CJ, Walton RT, Martineau AR.

Br J Nutr. 2018 Oct;120(8):891-900. doi: 10.1017/S000711451800209X. Epub 2018 Aug 22.

7.

A randomised open-label cross-over study of inhaler errors, preference and time to achieve correct inhaler use in patients with COPD or asthma: comparison of ELLIPTA with other inhaler devices.

van der Palen J, Thomas M, Chrystyn H, Sharma RK, van der Valk PD, Goosens M, Wilkinson T, Stonham C, Chauhan AJ, Imber V, Zhu CQ, Svedsater H, Barnes NC.

NPJ Prim Care Respir Med. 2017 Mar 23;27:17001. doi: 10.1038/npjpcrm.2017.1. No abstract available.

8.

Prevalence, determinants and clinical correlates of vitamin D deficiency in patients with Chronic Obstructive Pulmonary Disease in London, UK.

Jolliffe DA, James WY, Hooper RL, Barnes NC, Greiller CL, Islam K, Bhowmik A, Timms PM, Rajakulasingam RK, Choudhury AB, Simcock DE, Hyppönen E, Walton RT, Corrigan CJ, Griffiths CJ, Martineau AR.

J Steroid Biochem Mol Biol. 2018 Jan;175:138-145. doi: 10.1016/j.jsbmb.2017.01.019. Epub 2017 Feb 1.

9.

Evaluating the risk of pneumonia with inhaled corticosteroids in COPD: Retrospective database studies have their limitations SA.

Bourbeau J, Aaron SD, Barnes NC, Davis KJ, Lacasse Y, Nadeau G.

Respir Med. 2017 Feb;123:94-97. doi: 10.1016/j.rmed.2016.12.015. Epub 2016 Dec 23. Review.

10.

Interpreting patient-reported outcomes from clinical trials in COPD: a discussion.

Jones PW, Rennard S, Tabberer M, Riley JH, Vahdati-Bolouri M, Barnes NC.

Int J Chron Obstruct Pulmon Dis. 2016 Dec 7;11:3069-3078. eCollection 2016. Review.

11.

A randomised open-label cross-over study of inhaler errors, preference and time to achieve correct inhaler use in patients with COPD or asthma: comparison of ELLIPTA with other inhaler devices.

van der Palen J, Thomas M, Chrystyn H, Sharma RK, van der Valk PD, Goosens M, Wilkinson T, Stonham C, Chauhan AJ, Imber V, Zhu CQ, Svedsater H, Barnes NC.

NPJ Prim Care Respir Med. 2016 Nov 24;26:16079. doi: 10.1038/npjpcrm.2016.79. Erratum in: NPJ Prim Care Respir Med. 2017 Mar 23;27:17001.

12.

Prevalence, determinants and clinical correlates of vitamin D deficiency in adults with inhaled corticosteroid-treated asthma in London, UK.

Jolliffe DA, Kilpin K, MacLaughlin BD, Greiller CL, Hooper RL, Barnes NC, Timms PM, Rajakulasingam RK, Bhowmik A, Choudhury AB, Simcock DE, Hyppönen E, Corrigan CJ, Walton RT, Griffiths CJ, Martineau AR.

J Steroid Biochem Mol Biol. 2018 Jan;175:88-96. doi: 10.1016/j.jsbmb.2016.11.004. Epub 2016 Nov 5.

PMID:
27825992
13.

The frequency of, and adherence to, single maintenance and reliever therapy instructions in asthma: a descriptive analysis.

DiSantostefano RL, Boudiaf N, Stempel DA, Barnes NC, Greening AP.

NPJ Prim Care Respir Med. 2016 Jul 21;26:16038. doi: 10.1038/npjpcrm.2016.38.

14.

Blood eosinophils as a marker of response to inhaled corticosteroids in COPD.

Barnes NC, Sharma R, Lettis S, Calverley PM.

Eur Respir J. 2016 May;47(5):1374-82. doi: 10.1183/13993003.01370-2015. Epub 2016 Feb 25.

15.

Relationship between blood eosinophils and clinical characteristics in a cross-sectional study of a US population-based COPD cohort.

DiSantostefano RL, Hinds D, Le HV, Barnes NC.

Respir Med. 2016 Mar;112:88-96. doi: 10.1016/j.rmed.2016.01.013. Epub 2016 Jan 22.

16.

Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD.

Pavord ID, Lettis S, Locantore N, Pascoe S, Jones PW, Wedzicha JA, Barnes NC.

Thorax. 2016 Feb;71(2):118-25. doi: 10.1136/thoraxjnl-2015-207021. Epub 2015 Nov 19.

17.

Lung Deflation and Cardiovascular Structure and Function in Chronic Obstructive Pulmonary Disease. A Randomized Controlled Trial.

Stone IS, Barnes NC, James WY, Midwinter D, Boubertakh R, Follows R, John L, Petersen SE.

Am J Respir Crit Care Med. 2016 Apr 1;193(7):717-26. doi: 10.1164/rccm.201508-1647OC.

18.
19.

Blood eosinophil counts as markers of response to inhaled corticosteroids in COPD?--Authors' reply.

Pascoe S, Locantore N, Dransfield MT, Barnes NC, Pavord I.

Lancet Respir Med. 2015 Aug;3(8):e27. doi: 10.1016/S2213-2600(15)00259-3. No abstract available.

PMID:
26282479
20.

Double-blind randomised controlled trial of vitamin D3 supplementation for the prevention of acute respiratory infection in older adults and their carers (ViDiFlu).

Martineau AR, Hanifa Y, Witt KD, Barnes NC, Hooper RL, Patel M, Stevens N, Enayat Z, Balayah Z, Syed A, Knight A, Jolliffe DA, Greiller CL, McLaughlin D, Venton TR, Rowe M, Timms PM, Clark D, Sadique Z, Eldridge SM, Griffiths CJ.

Thorax. 2015 Oct;70(10):953-60. doi: 10.1136/thoraxjnl-2015-206996. Epub 2015 Jun 10.

PMID:
26063508
21.
22.

Double-blind randomised placebo-controlled trial of bolus-dose vitamin D3 supplementation in adults with asthma (ViDiAs).

Martineau AR, MacLaughlin BD, Hooper RL, Barnes NC, Jolliffe DA, Greiller CL, Kilpin K, McLaughlin D, Fletcher G, Mein CA, Hoti M, Walton R, Grigg J, Timms PM, Rajakulasingam RK, Bhowmik A, Rowe M, Venton TR, Choudhury AB, Simcock DE, Sadique Z, Monteiro WR, Corrigan CJ, Hawrylowicz CM, Griffiths CJ.

Thorax. 2015 May;70(5):451-7. doi: 10.1136/thoraxjnl-2014-206449. Epub 2015 Feb 27.

PMID:
25724847
23.

Vitamin D3 supplementation in patients with chronic obstructive pulmonary disease (ViDiCO): a multicentre, double-blind, randomised controlled trial.

Martineau AR, James WY, Hooper RL, Barnes NC, Jolliffe DA, Greiller CL, Islam K, McLaughlin D, Bhowmik A, Timms PM, Rajakulasingam RK, Rowe M, Venton TR, Choudhury AB, Simcock DE, Wilks M, Degun A, Sadique Z, Monteiro WR, Corrigan CJ, Hawrylowicz CM, Griffiths CJ.

Lancet Respir Med. 2015 Feb;3(2):120-130. doi: 10.1016/S2213-2600(14)70255-3. Epub 2014 Dec 2.

PMID:
25476069
24.

Site-selective solid-phase synthesis of a CCR5 sulfopeptide library to interrogate HIV binding and entry.

Liu X, Malins LR, Roche M, Sterjovski J, Duncan R, Garcia ML, Barnes NC, Anderson DA, Stone MJ, Gorry PR, Payne RJ.

ACS Chem Biol. 2014 Sep 19;9(9):2074-81. doi: 10.1021/cb500337r. Epub 2014 Jul 24.

25.

Safety of tiotropium through the Handihaler: why did meta-analyses and database studies appear to give a false alarm?

Barnes NC, Jones PW, Davis KJ.

Thorax. 2014 Jun;69(6):598-9. doi: 10.1136/thoraxjnl-2014-205155. Epub 2014 Feb 18. No abstract available.

PMID:
24550061
26.
27.

Reproducibility of arterial stiffness and wave reflections in chronic obstructive pulmonary disease: the contribution of lung hyperinflation and a comparison of techniques.

Stone IS, John L, Petersen SE, Barnes NC.

Respir Med. 2013 Nov;107(11):1700-8. doi: 10.1016/j.rmed.2013.06.008. Epub 2013 Aug 3.

28.

Raised troponin in COPD: clinical implications and possible mechanisms.

Stone IS, Petersen SE, Barnes NC.

Heart. 2013 Jan;99(2):71-2. doi: 10.1136/heartjnl-2012-302969. Epub 2012 Nov 26. No abstract available.

PMID:
23184012
29.

Chronic obstructive pulmonary disease: a modifiable risk factor for cardiovascular disease?

Stone IS, Barnes NC, Petersen SE.

Heart. 2012 Jul;98(14):1055-62. doi: 10.1136/heartjnl-2012-301759. Review.

PMID:
22739636
30.

An oral inhibitor of p38 MAP kinase reduces plasma fibrinogen in patients with chronic obstructive pulmonary disease.

Lomas DA, Lipson DA, Miller BE, Willits L, Keene O, Barnacle H, Barnes NC, Tal-Singer R; Losmapimod Study Investigators.

J Clin Pharmacol. 2012 Mar;52(3):416-24. doi: 10.1177/0091270010397050. Epub 2011 Nov 16.

PMID:
22090363
31.

WITHDRAWN: Antibiotics for exacerbations of chronic obstructive pulmonary disease.

Ram FS, Rodriguez-Roisin R, Granados-Navarrete A, Garcia-Aymerich J, Barnes NC.

Cochrane Database Syst Rev. 2011 Jan 19;(1):CD004403. doi: 10.1002/14651858.CD004403.pub3. Review.

PMID:
21249661
32.

Single maintenance and reliever therapy (SMART) of asthma: a critical appraisal.

Chapman KR, Barnes NC, Greening AP, Jones PW, Pedersen S.

Thorax. 2010 Aug;65(8):747-52. doi: 10.1136/thx.2009.128504. Epub 2010 Jun 27. Review.

33.

Choosing inhaler devices for people with asthma: current knowledge and outstanding research needs.

Haughney J, Price D, Barnes NC, Virchow JC, Roche N, Chrystyn H.

Respir Med. 2010 Sep;104(9):1237-45. doi: 10.1016/j.rmed.2010.04.012. Epub 2010 May 15. Review.

34.

Intermittent use of inhaled corticosteroids for the treatment of mild asthma is not recommended.

Barnes NC, Douglas G, Higgins B.

Prim Care Respir J. 2009 Dec;18(4):341-2; author reply 342. doi: 10.4104/pcrj.2009.00066. No abstract available.

35.

Airway inflammation in patients with asthma with high-fixed or low-fixed plus as-needed budesonide/formoterol.

Pavord ID, Jeffery PK, Qiu Y, Zhu J, Parker D, Carlsheimer A, Naya I, Barnes NC.

J Allergy Clin Immunol. 2009 May;123(5):1083-9, 1089.e1-7. doi: 10.1016/j.jaci.2009.02.034. Epub 2009 Apr 14.

PMID:
19368965
36.

Reflections on TORCH: potential mechanisms for the survival benefit of salmeterol/fluticasone propionate in COPD patients.

Johnson M, Agusti AG, Barnes NC.

COPD. 2008 Dec;5(6):369-75. doi: 10.1080/15412550802522924.

PMID:
19353351
37.

Montelukast and bronchial inflammation in asthma: a randomised, double-blind placebo-controlled trial.

Ramsay CF, Sullivan P, Gizycki M, Wang D, Swern AS, Barnes NC, Reiss TF, Jeffery PK.

Respir Med. 2009 Jul;103(7):995-1003. doi: 10.1016/j.rmed.2009.01.019. Epub 2009 Feb 26.

38.

A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma.

Flood-Page P, Swenson C, Faiferman I, Matthews J, Williams M, Brannick L, Robinson D, Wenzel S, Busse W, Hansel TT, Barnes NC; International Mepolizumab Study Group.

Am J Respir Crit Care Med. 2007 Dec 1;176(11):1062-71. Epub 2007 Sep 13.

PMID:
17872493
39.

Eppur si muove, or COPD treatment success and inflammation.

Soriano JB, Barnes NC.

Eur Respir J. 2007 Sep;30(3):409-10. No abstract available.

41.

The properties of inhaled corticosteroids: similarities and differences.

Barnes NC.

Prim Care Respir J. 2007 Jun;16(3):149-54. Review.

42.

Airway mucosal inflammation in COPD is similar in smokers and ex-smokers: a pooled analysis.

Gamble E, Grootendorst DC, Hattotuwa K, O'Shaughnessy T, Ram FS, Qiu Y, Zhu J, Vignola AM, Kroegel C, Morell F, Pavord ID, Rabe KF, Jeffery PK, Barnes NC.

Eur Respir J. 2007 Sep;30(3):467-71. Epub 2007 May 15.

43.

Cigarette smoking alters bronchial mucosal immunity in asthma.

Tsoumakidou M, Elston W, Zhu J, Wang Z, Gamble E, Siafakas NM, Barnes NC, Jeffery PK.

Am J Respir Crit Care Med. 2007 May 1;175(9):919-25. Epub 2007 Feb 15.

PMID:
17303795
44.

Alteration of the Fc gamma RIIa dimer interface affects receptor signaling but not ligand binding.

Powell MS, Barnes NC, Bradford TM, Musgrave IF, Wines BD, Cambier JC, Hogarth PM.

J Immunol. 2006 Jun 15;176(12):7489-94.

45.

Reducing oral steroids with inhaled steroids: is that all that can be achieved?

Barnes NC.

Chest. 2006 May;129(5):1124-5. No abstract available.

PMID:
16685000
46.

Antibiotics for exacerbations of chronic obstructive pulmonary disease.

Ram FS, Rodriguez-Roisin R, Granados-Navarrete A, Garcia-Aymerich J, Barnes NC.

Cochrane Database Syst Rev. 2006 Apr 19;(2):CD004403. Review. Update in: Cochrane Database Syst Rev. 2011;(1):CD004403.

PMID:
16625602
47.

Sputum induction in corticosteroid-dependant asthmatics: risks and airway cellular profile.

Loh LC, Kanabar V, D'Amato M, Barnes NC, O'Connor BJ.

Asian Pac J Allergy Immunol. 2005 Dec;23(4):189-96.

48.

Variability of bronchial inflammation in chronic obstructive pulmonary disease: implications for study design.

Gamble E, Qiu Y, Wang D, Zhu J, Vignola AM, Kroegel C, Morell F, Hansel TT, Pavord ID, Rabe KF, Barnes NC, Jeffery PK.

Eur Respir J. 2006 Feb;27(2):293-9.

49.

Antiinflammatory effects of salmeterol/fluticasone propionate in chronic obstructive lung disease.

Barnes NC, Qiu YS, Pavord ID, Parker D, Davis PA, Zhu J, Johnson M, Thomson NC, Jeffery PK; SCO30005 Study Group.

Am J Respir Crit Care Med. 2006 Apr 1;173(7):736-43. Epub 2006 Jan 19.

PMID:
16424444
50.

Raft localisation of FcgammaRIIa and efficient signaling are dependent on palmitoylation of cysteine 208.

Barnes NC, Powell MS, Trist HM, Gavin AL, Wines BD, Hogarth PM.

Immunol Lett. 2006 Apr 15;104(1-2):118-23. Epub 2005 Dec 5.

PMID:
16375976

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