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Items: 20

1.

Clinical and Genomic Implications of Luminal and Basal Subtypes Across Carcinomas.

Zhao SG, Chen WS, Das R, Chang SL, Tomlins SA, Chou J, Quigley DA, Dang HX, Barnard TJ, Mahal BA, Gibb EA, Liu Y, Davicioni E, Duska LR, Posadas EM, Jolly S, Spratt DE, Nguyen PL, Maher CA, Small EJ, Feng FY.

Clin Cancer Res. 2019 Apr 15;25(8):2450-2457. doi: 10.1158/1078-0432.CCR-18-3121. Epub 2018 Dec 20.

PMID:
30573691
2.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Quigley DA, Dang HX, Zhao SG, Lloyd P, Aggarwal R, Alumkal JJ, Foye A, Kothari V, Perry MD, Bailey AM, Playdle D, Barnard TJ, Zhang L, Zhang J, Youngren JF, Cieslik MP, Parolia A, Beer TM, Thomas G, Chi KN, Gleave M, Lack NA, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Ryan CJ, Fong L, Kim W, Friedlander T, Chou J, Li H, Das R, Li H, Moussavi-Baygi R, Goodarzi H, Gilbert LA, Lara PN Jr, Evans CP, Goldstein TC, Stuart JM, Tomlins SA, Spratt DE, Cheetham RK, Cheng DT, Farh K, Gehring JS, Hakenberg J, Liao A, Febbo PG, Shon J, Sickler B, Batzoglou S, Knudsen KE, He HH, Huang J, Wyatt AW, Dehm SM, Ashworth A, Chinnaiyan AM, Maher CA, Small EJ, Feng FY.

Cell. 2018 Oct 18;175(3):889. doi: 10.1016/j.cell.2018.10.019. No abstract available.

3.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Quigley DA, Dang HX, Zhao SG, Lloyd P, Aggarwal R, Alumkal JJ, Foye A, Kothari V, Perry MD, Bailey AM, Playdle D, Barnard TJ, Zhang L, Zhang J, Youngren JF, Cieslik MP, Parolia A, Beer TM, Thomas G, Chi KN, Gleave M, Lack NA, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Ryan CJ, Fong L, Kim W, Friedlander T, Chou J, Li H, Das R, Li H, Moussavi-Baygi R, Goodarzi H, Gilbert LA, Lara PN Jr, Evans CP, Goldstein TC, Stuart JM, Tomlins SA, Spratt DE, Cheetham RK, Cheng DT, Farh K, Gehring JS, Hakenberg J, Liao A, Febbo PG, Shon J, Sickler B, Batzoglou S, Knudsen KE, He HH, Huang J, Wyatt AW, Dehm SM, Ashworth A, Chinnaiyan AM, Maher CA, Small EJ, Feng FY.

Cell. 2018 Jul 26;174(3):758-769.e9. doi: 10.1016/j.cell.2018.06.039. Epub 2018 Jul 19. Erratum in: Cell. 2018 Oct 18;175(3):889.

4.

Structural insight into the role of the Ton complex in energy transduction.

Celia H, Noinaj N, Zakharov SD, Bordignon E, Botos I, Santamaria M, Barnard TJ, Cramer WA, Lloubes R, Buchanan SK.

Nature. 2016 Oct 6;538(7623):60-65. doi: 10.1038/nature19757. Epub 2016 Sep 21.

5.

Structural and Functional Characterization of the LPS Transporter LptDE from Gram-Negative Pathogens.

Botos I, Majdalani N, Mayclin SJ, McCarthy JG, Lundquist K, Wojtowicz D, Barnard TJ, Gumbart JC, Buchanan SK.

Structure. 2016 Jun 7;24(6):965-976. doi: 10.1016/j.str.2016.03.026. Epub 2016 May 5.

6.

An engineered palette of metal ion quenchable fluorescent proteins.

Yu X, Strub MP, Barnard TJ, Noinaj N, Piszczek G, Buchanan SK, Taraska JW.

PLoS One. 2014 Apr 21;9(4):e95808. doi: 10.1371/journal.pone.0095808. eCollection 2014.

7.

Specific targeting and killing of Gram-negative pathogens with an engineered phage lytic enzyme.

Lukacik P, Barnard TJ, Hinnebusch BJ, Buchanan SK.

Virulence. 2013 Jan 1;4(1):90-1. doi: 10.4161/viru.22683. No abstract available.

8.

Using a bacteriocin structure to engineer a phage lysin that targets Yersinia pestis.

Lukacik P, Barnard TJ, Buchanan SK.

Biochem Soc Trans. 2012 Dec 1;40(6):1503-6. doi: 10.1042/BST20120209.

9.

Structural engineering of a phage lysin that targets gram-negative pathogens.

Lukacik P, Barnard TJ, Keller PW, Chaturvedi KS, Seddiki N, Fairman JW, Noinaj N, Kirby TL, Henderson JP, Steven AC, Hinnebusch BJ, Buchanan SK.

Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9857-62. doi: 10.1073/pnas.1203472109. Epub 2012 Jun 7.

10.

Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis.

Fairman JW, Dautin N, Wojtowicz D, Liu W, Noinaj N, Barnard TJ, Udho E, Przytycka TM, Cherezov V, Buchanan SK.

Structure. 2012 Jul 3;20(7):1233-43. doi: 10.1016/j.str.2012.04.011. Epub 2012 May 31.

11.

Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter.

Barnard TJ, Gumbart J, Peterson JH, Noinaj N, Easley NC, Dautin N, Kuszak AJ, Tajkhorshid E, Bernstein HD, Buchanan SK.

J Mol Biol. 2012 Jan 6;415(1):128-42. doi: 10.1016/j.jmb.2011.10.049. Epub 2011 Nov 7.

12.

Structural insights into Ail-mediated adhesion in Yersinia pestis.

Yamashita S, Lukacik P, Barnard TJ, Noinaj N, Felek S, Tsang TM, Krukonis ES, Hinnebusch BJ, Buchanan SK.

Structure. 2011 Nov 9;19(11):1672-82. doi: 10.1016/j.str.2011.08.010.

13.

TonB-dependent transporters: regulation, structure, and function.

Noinaj N, Guillier M, Barnard TJ, Buchanan SK.

Annu Rev Microbiol. 2010;64:43-60. doi: 10.1146/annurev.micro.112408.134247. Review.

14.

Crystallization of integral membrane proteins.

Barnard TJ, Wally JL, Buchanan SK.

Curr Protoc Protein Sci. 2007 Feb;Chapter 17:Unit 17.9. doi: 10.1002/0471140864.ps1709s47.

PMID:
18429311
15.

Autotransporter structure reveals intra-barrel cleavage followed by conformational changes.

Barnard TJ, Dautin N, Lukacik P, Bernstein HD, Buchanan SK.

Nat Struct Mol Biol. 2007 Dec;14(12):1214-20. Epub 2007 Nov 11.

16.

Structure of colicin I receptor bound to the R-domain of colicin Ia: implications for protein import.

Buchanan SK, Lukacik P, Grizot S, Ghirlando R, Ali MM, Barnard TJ, Jakes KS, Kienker PK, Esser L.

EMBO J. 2007 May 16;26(10):2594-604. Epub 2007 Apr 26.

17.

Cleavage of a bacterial autotransporter by an evolutionarily convergent autocatalytic mechanism.

Dautin N, Barnard TJ, Anderson DE, Bernstein HD.

EMBO J. 2007 Apr 4;26(7):1942-52. Epub 2007 Mar 8.

18.

Efficient secretion of a folded protein domain by a monomeric bacterial autotransporter.

Skillman KM, Barnard TJ, Peterson JH, Ghirlando R, Bernstein HD.

Mol Microbiol. 2005 Nov;58(4):945-58.

19.

IroN functions as a siderophore receptor and is a urovirulence factor in an extraintestinal pathogenic isolate of Escherichia coli.

Russo TA, McFadden CD, Carlino-MacDonald UB, Beanan JM, Barnard TJ, Johnson JR.

Infect Immun. 2002 Dec;70(12):7156-60.

20.

Mutations in the Escherichia coli receptor FepA reveal residues involved in ligand binding and transport.

Barnard TJ, Watson ME Jr, McIntosh MA.

Mol Microbiol. 2001 Aug;41(3):527-36.

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