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Items: 1 to 50 of 76

1.

HIV-1 matrix trimerization-impaired mutants are rescued by matrix substitutions that enhance envelope glycoprotein incorporation.

Tedbury PR, Novikova M, Alfadhli A, Hikichi Y, Kagiampakis I, KewalRamani VN, Barklis E, Freed EO.

J Virol. 2019 Oct 16. pii: JVI.01526-19. doi: 10.1128/JVI.01526-19. [Epub ahead of print]

PMID:
31619553
2.

Replication of HIV-1 envelope protein cytoplasmic domain variants in permissive and restrictive cells.

Staubus AO, Alfadhli A, Barklis RL, Barklis E.

Virology. 2019 Sep 18;538:1-10. doi: 10.1016/j.virol.2019.09.008. [Epub ahead of print]

PMID:
31550607
3.

Analysis of HIV-1 Matrix-Envelope Cytoplasmic Tail Interactions.

Alfadhli A, Staubus AO, Tedbury PR, Novikova M, Freed EO, Barklis E.

J Virol. 2019 Oct 15;93(21). pii: e01079-19. doi: 10.1128/JVI.01079-19. Print 2019 Nov 1.

PMID:
31375589
4.

Organization of Farnesylated, Carboxymethylated KRAS4B on Membranes.

Barklis E, Stephen AG, Staubus AO, Barklis RL, Alfadhli A.

J Mol Biol. 2019 Sep 6;431(19):3706-3717. doi: 10.1016/j.jmb.2019.07.025. Epub 2019 Jul 19.

PMID:
31330153
5.

Lipid biosensor interactions with wild type and matrix deletion HIV-1 Gag proteins.

Barklis E, Staubus AO, Mack A, Harper L, Barklis RL, Alfadhli A.

Virology. 2018 May;518:264-271. doi: 10.1016/j.virol.2018.03.004. Epub 2018 Mar 15.

6.

Analysis of K-Ras Interactions by Biotin Ligase Tagging.

Ritchie C, Mack A, Harper L, Alfadhli A, Stork PJS, Nan X, Barklis E.

Cancer Genomics Proteomics. 2017 Jul-Aug;14(4):225-239.

7.

Analysis of quinolinequinone reactivity, cytotoxicity, and anti-HIV-1 properties.

Alfadhli A, Mack A, Harper L, Berk S, Ritchie C, Barklis E.

Bioorg Med Chem. 2016 Nov 1;24(21):5618-5625. doi: 10.1016/j.bmc.2016.09.028. Epub 2016 Sep 12.

8.

Trimer Enhancement Mutation Effects on HIV-1 Matrix Protein Binding Activities.

Alfadhli A, Mack A, Ritchie C, Cylinder I, Harper L, Tedbury PR, Freed EO, Barklis E.

J Virol. 2016 May 27;90(12):5657-5664. doi: 10.1128/JVI.00509-16. Print 2016 Jun 15.

9.

Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.

Ritchie C, Cylinder I, Platt EJ, Barklis E.

J Virol. 2015 Apr;89(7):3988-4001. doi: 10.1128/JVI.03584-14. Epub 2015 Jan 28.

10.

RRE-dependent HIV-1 Env RNA effects on Gag protein expression, assembly and release.

López CS, Sloan R, Cylinder I, Kozak SL, Kabat D, Barklis E.

Virology. 2014 Aug;462-463:126-34. doi: 10.1016/j.virol.2014.05.019. Epub 2014 Jun 25.

11.

The roles of lipids and nucleic acids in HIV-1 assembly.

Alfadhli A, Barklis E.

Front Microbiol. 2014 May 28;5:253. doi: 10.3389/fmicb.2014.00253. eCollection 2014. Review.

12.

Second site reversion of a mutation near the amino terminus of the HIV-1 capsid protein.

López CS, Tsagli SM, Sloan R, Eccles J, Barklis E.

Virology. 2013 Dec;447(1-2):95-103. doi: 10.1016/j.virol.2013.08.023. Epub 2013 Sep 21.

13.

Analysis of small molecule ligands targeting the HIV-1 matrix protein-RNA binding site.

Alfadhli A, McNett H, Eccles J, Tsagli S, Noviello C, Sloan R, López CS, Peyton DH, Barklis E.

J Biol Chem. 2013 Jan 4;288(1):666-76. doi: 10.1074/jbc.M112.399865. Epub 2012 Nov 7.

14.

HIV-1 matrix protein binding to RNA.

Alfadhli A, McNett H, Tsagli S, Bächinger HP, Peyton DH, Barklis E.

J Mol Biol. 2011 Jul 22;410(4):653-66. doi: 10.1016/j.jmb.2011.04.063.

15.

Determinants of the HIV-1 core assembly pathway.

López CS, Eccles JD, Still A, Sloan RE, Barklis RL, Tsagli SM, Barklis E.

Virology. 2011 Aug 15;417(1):137-46. doi: 10.1016/j.virol.2011.05.011. Epub 2011 Jun 14.

16.

Second-site compensatory mutations of HIV-1 capsid mutations.

Noviello CM, López CS, Kukull B, McNett H, Still A, Eccles J, Sloan R, Barklis E.

J Virol. 2011 May;85(10):4730-8. doi: 10.1128/JVI.00099-11. Epub 2011 Mar 2.

17.

Analysis of the N-terminal region of the murine leukemia virus nucleocapsid protein.

Still A, Huseby D, Barklis E.

Virus Res. 2011 Jan;155(1):181-8. doi: 10.1016/j.virusres.2010.10.001. Epub 2010 Oct 8.

18.

Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action.

Dikeakos JD, Atkins KM, Thomas L, Emert-Sedlak L, Byeon IJ, Jung J, Ahn J, Wortman MD, Kukull B, Saito M, Koizumi H, Williamson DM, Hiyoshi M, Barklis E, Takiguchi M, Suzu S, Gronenborn AM, Smithgall TE, Thomas G.

Mol Biol Cell. 2010 Oct 1;21(19):3279-92. doi: 10.1091/mbc.E10-05-0470. Epub 2010 Aug 11.

19.

Structure-specific recognition protein 1 facilitates microtubule growth and bundling required for mitosis.

Zeng SX, Li Y, Jin Y, Zhang Q, Keller DM, McQuaw CM, Barklis E, Stone S, Hoatlin M, Zhao Y, Lu H.

Mol Cell Biol. 2010 Feb;30(4):935-47. doi: 10.1128/MCB.01379-09. Epub 2009 Dec 7.

20.

Analysis of human immunodeficiency virus type 1 matrix binding to membranes and nucleic acids.

Alfadhli A, Still A, Barklis E.

J Virol. 2009 Dec;83(23):12196-203. doi: 10.1128/JVI.01197-09. Epub 2009 Sep 23.

21.

Characterization of the in vitro HIV-1 capsid assembly pathway.

Barklis E, Alfadhli A, McQuaw C, Yalamuri S, Still A, Barklis RL, Kukull B, López CS.

J Mol Biol. 2009 Mar 27;387(2):376-89. doi: 10.1016/j.jmb.2009.01.058. Epub 2009 Feb 3.

22.

HIV-1 matrix organizes as a hexamer of trimers on membranes containing phosphatidylinositol-(4,5)-bisphosphate.

Alfadhli A, Barklis RL, Barklis E.

Virology. 2009 May 10;387(2):466-72. doi: 10.1016/j.virol.2009.02.048. Epub 2009 Mar 27.

23.

HIV-1 Nef assembles a Src family kinase-ZAP-70/Syk-PI3K cascade to downregulate cell-surface MHC-I.

Hung CH, Thomas L, Ruby CE, Atkins KM, Morris NP, Knight ZA, Scholz I, Barklis E, Weinberg AD, Shokat KM, Thomas G.

Cell Host Microbe. 2007 Apr 19;1(2):121-33.

24.

Analysis of human immunodeficiency virus matrix domain replacements.

Scholz I, Still A, Dhenub TC, Coday K, Webb M, Barklis E.

Virology. 2008 Feb 20;371(2):322-35. Epub 2007 Nov 8.

25.

Sultam thiourea inhibition of West Nile virus.

Barklis E, Still A, Sabri MI, Hirsch AJ, Nikolich-Zugich J, Brien J, Dhenub TC, Scholz I, Alfadhli A.

Antimicrob Agents Chemother. 2007 Jul;51(7):2642-5. Epub 2007 Apr 23.

26.

Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer.

Alfadhli A, Huseby D, Kapit E, Colman D, Barklis E.

J Virol. 2007 Feb;81(3):1472-8. Epub 2006 Nov 15.

27.

Analysis of human immunodeficiency virus type 1 Gag dimerization-induced assembly.

Alfadhli A, Dhenub TC, Still A, Barklis E.

J Virol. 2005 Dec;79(23):14498-506.

28.

Mutations affecting cleavage at the p10-capsid protease cleavage site block Rous sarcoma virus replication.

Vana ML, Chen A, Boross P, Weber I, Colman D, Barklis E, Leis J.

Retrovirology. 2005 Sep 27;2:58.

29.

Assembly of human immunodeficiency virus precursor gag proteins.

Huseby D, Barklis RL, Alfadhli A, Barklis E.

J Biol Chem. 2005 May 6;280(18):17664-70. Epub 2005 Feb 25.

30.
31.

Analysis of the retrovirus capsid interdomain linker region.

Arvidson B, Seeds J, Webb M, Finlay L, Barklis E.

Virology. 2003 Mar 30;308(1):166-77.

32.

Antiviral inhibition of the HIV-1 capsid protein.

Tang C, Loeliger E, Kinde I, Kyere S, Mayo K, Barklis E, Sun Y, Huang M, Summers MF.

J Mol Biol. 2003 Apr 11;327(5):1013-20.

PMID:
12662926
33.

Retrovirus capsid protein assembly arrangements.

Mayo K, Huseby D, McDermott J, Arvidson B, Finlay L, Barklis E.

J Mol Biol. 2003 Jan 3;325(1):225-37.

PMID:
12473464
34.

EMXtalOrg: an EM tilt data organization and processing system.

McDermott J, Barklis E.

Ultramicroscopy. 2002 Oct;93(1):11-7.

PMID:
12380647
35.

Hexagonal organization of Moloney murine leukemia virus capsid proteins.

Mayo K, McDermott J, Barklis E.

Virology. 2002 Jun 20;298(1):30-8.

36.

Hantavirus nucleocapsid protein coiled-coil domains.

Alfadhli A, Steel E, Finlay L, Bächinger HP, Barklis E.

J Biol Chem. 2002 Jul 26;277(30):27103-8. Epub 2002 May 17.

37.

Analysis of Rous sarcoma virus capsid protein variants assembled on lipid monolayers.

Mayo K, Vana ML, McDermott J, Huseby D, Leis J, Barklis E.

J Mol Biol. 2002 Feb 22;316(3):667-78.

PMID:
11866525
38.

Hantavirus nucleocapsid protein oligomerization.

Alfadhli A, Love Z, Arvidson B, Seeds J, Willey J, Barklis E.

J Virol. 2001 Feb;75(4):2019-23.

39.

Three-dimensional organization of retroviral capsid proteins on a lipid monolayer.

McDermott J, Mayo K, Barklis E.

J Mol Biol. 2000 Sep 8;302(1):121-33.

PMID:
10964565
40.

Assembly of retrovirus capsid-nucleocapsid proteins in the presence of membranes or RNA.

Zuber G, McDermott J, Karanjia S, Zhao W, Schmid MF, Barklis E.

J Virol. 2000 Aug;74(16):7431-41.

41.
44.

Organization of HIV-1 capsid proteins on a lipid monolayer.

Barklis E, McDermott J, Wilkens S, Fuller S, Thompson D.

J Biol Chem. 1998 Mar 27;273(13):7177-80.

45.
47.
48.

Partial isolation from intact cells of a cell surface-exposed lysophosphatidylinositol-phospholipase C.

Birrell GB, Hedberg KK, Barklis E, Griffith OH.

J Cell Biochem. 1997 Jun 15;65(4):550-64.

PMID:
9178104
49.

Structural analysis of membrane-bound retrovirus capsid proteins.

Barklis E, McDermott J, Wilkens S, Schabtach E, Schmid MF, Fuller S, Karanjia S, Love Z, Jones R, Rui Y, Zhao X, Thompson D.

EMBO J. 1997 Mar 17;16(6):1199-213.

50.

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