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Items: 18

1.

A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping.

Demonbreun AR, Wyatt EJ, Fallon KS, Oosterbaan CC, Page PG, Hadhazy M, Quattrocelli M, Barefield DY, McNally EM.

Dis Model Mech. 2019 Nov 4;13(2). pii: dmm040832. doi: 10.1242/dmm.040832.

2.

Recombinant annexin A6 promotes membrane repair and protects against muscle injury.

Demonbreun AR, Fallon KS, Oosterbaan CC, Bogdanovic E, Warner JL, Sell JJ, Page PG, Quattrocelli M, Barefield DY, McNally EM.

J Clin Invest. 2019 Nov 1;129(11):4657-4670. doi: 10.1172/JCI128840.

3.

Deletion of Sulfonylurea Receptor 2 in the Adult Myocardium Enhances Cardiac Glucose Uptake and Is Cardioprotective.

Aubert G, Barefield DY, Demonbreun AR, Ramratnam M, Fallon KS, Warner JL, Rossi AE, Hadhazy M, Makielski JC, McNally EM.

JACC Basic Transl Sci. 2019 Apr 29;4(2):251-268. doi: 10.1016/j.jacbts.2018.11.012. eCollection 2019 Apr.

4.

Altered C10 domain in cardiac myosin binding protein-C results in hypertrophic cardiomyopathy.

Kuster DWD, Lynch TL, Barefield DY, Sivaguru M, Kuffel G, Zilliox MJ, Lee KH, Craig R, Namakkal-Soorappan R, Sadayappan S.

Cardiovasc Res. 2019 Dec 1;115(14):1986-1997. doi: 10.1093/cvr/cvz111.

PMID:
31050699
5.

Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury.

Barefield DY, McNamara JW, Lynch TL, Kuster DWD, Govindan S, Haar L, Wang Y, Taylor EN, Lorenz JN, Nieman ML, Zhu G, Luther PK, Varr├│ A, Dobrev D, Ai X, Janssen PML, Kass DA, Jones WK, Gilbert RJ, Sadayappan S.

J Mol Cell Cardiol. 2019 Apr;129:236-246. doi: 10.1016/j.yjmcc.2019.03.006. Epub 2019 Mar 9.

6.

Distinct pathological signatures in human cellular models of myotonic dystrophy subtypes.

Kim EY, Barefield DY, Vo AH, Gacita AM, Schuster EJ, Wyatt EJ, Davis JL, Dong B, Sun C, Page P, Dellefave-Castillo L, Demonbreun A, Zhang HF, McNally EM.

JCI Insight. 2019 Mar 21;4(6). pii: 122686. doi: 10.1172/jci.insight.122686. eCollection 2019 Mar 21.

7.

Highlights from the American Heart Association's Basic Cardiovascular Science 2018 Scientific Sessions.

Barefield DY, Garbincius JF.

J Am Heart Assoc. 2018 Nov 20;7(22):e011097. doi: 10.1161/JAHA.118.011097. No abstract available.

8.

Transgenic overexpression of the SUR2A-55 splice variant in mouse heart reduces infract size and promotes protective mitochondrial function.

Ramratnam M, Kenny B, Kyle JW, Wiedmeyer B, Hacker TA, Barefield DY, McNally EM, Makielski JC.

Heliyon. 2018 Jul 4;4(7):e00677. doi: 10.1016/j.heliyon.2018.e00677. eCollection 2018 Jul.

9.

It Takes a Village to Train a Scientist.

Barefield DY.

Circ Res. 2017 Sep 29;121(8):908-909. doi: 10.1161/CIRCRESAHA.117.311485. No abstract available.

10.

The naked mole-rat exhibits an unusual cardiac myofilament protein profile providing new insights into heart function of this naturally subterranean rodent.

Grimes KM, Barefield DY, Kumar M, McNamara JW, Weintraub ST, de Tombe PP, Sadayappan S, Buffenstein R.

Pflugers Arch. 2017 Dec;469(12):1603-1613. doi: 10.1007/s00424-017-2046-3. Epub 2017 Aug 5.

11.

Experimental Modeling Supports a Role for MyBP-HL as a Novel Myofilament Component in Arrhythmia and Dilated Cardiomyopathy.

Barefield DY, Puckelwartz MJ, Kim EY, Wilsbacher LD, Vo AH, Waters EA, Earley JU, Hadhazy M, Dellefave-Castillo L, Pesce LL, McNally EM.

Circulation. 2017 Oct 17;136(16):1477-1491. doi: 10.1161/CIRCULATIONAHA.117.028585. Epub 2017 Aug 4.

12.

Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy.

Quattrocelli M, Barefield DY, Warner JL, Vo AH, Hadhazy M, Earley JU, Demonbreun AR, McNally EM.

J Clin Invest. 2017 Jun 1;127(6):2418-2432. doi: 10.1172/JCI91445. Epub 2017 May 8.

13.

High-Throughput Diagnostic Assay for a Highly Prevalent Cardiomyopathy-Associated MYBPC3 Variant.

Barefield DY, Lynch TL 4th, Jagadeesan A, Sanagala T, Sadayappan S.

J Mol Biomark Diagn. 2016 Nov;7(6). pii: 303. Epub 2016 Sep 30.

14.

An actin-dependent annexin complex mediates plasma membrane repair in muscle.

Demonbreun AR, Quattrocelli M, Barefield DY, Allen MV, Swanson KE, McNally EM.

J Cell Biol. 2016 Jun 20;213(6):705-18. doi: 10.1083/jcb.201512022. Epub 2016 Jun 13.

15.

Enhanced Muscular Dystrophy from Loss of Dysferlin Is Accompanied by Impaired Annexin A6 Translocation after Sarcolemmal Disruption.

Demonbreun AR, Allen MV, Warner JL, Barefield DY, Krishnan S, Swanson KE, Earley JU, McNally EM.

Am J Pathol. 2016 Jun;186(6):1610-22. doi: 10.1016/j.ajpath.2016.02.005. Epub 2016 Apr 9.

16.

Alterations in Multi-Scale Cardiac Architecture in Association With Phosphorylation of Myosin Binding Protein-C.

Taylor EN, Hoffman MP, Barefield DY, Aninwene GE 2nd, Abrishamchi AD, Lynch TL 4th, Govindan S, Osinska H, Robbins J, Sadayappan S, Gilbert RJ.

J Am Heart Assoc. 2016 Mar 15;5(3):e002836. doi: 10.1161/JAHA.115.002836.

17.

Reengineering a transmembrane protein to treat muscular dystrophy using exon skipping.

Gao QQ, Wyatt E, Goldstein JA, LoPresti P, Castillo LM, Gazda A, Petrossian N, Earley JU, Hadhazy M, Barefield DY, Demonbreun AR, B├Ânnemann C, Wolf M, McNally EM.

J Clin Invest. 2015 Nov 2;125(11):4186-95. doi: 10.1172/JCI82768. Epub 2015 Oct 12.

18.

The genetic landscape of cardiomyopathy and its role in heart failure.

McNally EM, Barefield DY, Puckelwartz MJ.

Cell Metab. 2015 Feb 3;21(2):174-182. doi: 10.1016/j.cmet.2015.01.013. Review.

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