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Items: 17


Potent and conditional redirected T cell killing of tumor cells using Half DVD-Ig.

Bardwell PD, Staron MM, Liu J, Tao Q, Scesney S, Bukofzer G, Rodriguez LE, Choi CH, Wang J, Chang Q, Dong F, Donawho C, Wang J, Grinnell CM, Tarcsa E, Hutchins C, Ghayur T, Gu J.

Protein Cell. 2018 Jan;9(1):121-129. doi: 10.1007/s13238-017-0429-z. Epub 2017 Jun 5.


Targeting apoptosis to induce stable mixed hematopoietic chimerism and long-term allograft survival without myelosuppressive conditioning in mice.

Cippà PE, Gabriel SS, Chen J, Bardwell PD, Bushell A, Guimezanes A, Kraus AK, Wekerle T, Wüthrich RP, Fehr T.

Blood. 2013 Aug 29;122(9):1669-77. doi: 10.1182/blood-2012-09-453944. Epub 2013 Jul 18.


Resistance to ABT-737 in activated T lymphocytes: molecular mechanisms and reversibility by inhibition of the calcineurin-NFAT pathway.

Cippà PE, Kraus AK, Lindenmeyer MT, Chen J, Guimezanes A, Bardwell PD, Wekerle T, Wüthrich RP, Fehr T.

Cell Death Dis. 2012 Apr 19;3:e299. doi: 10.1038/cddis.2012.38.


B-cell-dependent memory T cells impede nonmyeloablative mixed chimerism induction in presensitized mice.

Levesque V, Bardwell PD, Shimizu I, Haspot F, Benichou G, Yeap BY, Sykes M.

Am J Transplant. 2011 Nov;11(11):2322-31. doi: 10.1111/j.1600-6143.2011.03683.x. Epub 2011 Aug 10.


The BH3-mimetic ABT-737 inhibits allogeneic immune responses.

Cippà PE, Kraus AK, Edenhofer I, Segerer S, Chen J, Hausmann M, Liu Y, Guimezanes A, Bardwell PD, Wüthrich RP, Fehr T.

Transpl Int. 2011 Jul;24(7):722-32. doi: 10.1111/j.1432-2277.2011.01272.x. Epub 2011 May 25.


The Bcl-2 family antagonist ABT-737 significantly inhibits multiple animal models of autoimmunity.

Bardwell PD, Gu J, McCarthy D, Wallace C, Bryant S, Goess C, Mathieu S, Grinnell C, Erickson J, Rosenberg SH, Schwartz AJ, Hugunin M, Tarcsa E, Elmore SW, McRae B, Murtaza A, Wang LC, Ghayur T.

J Immunol. 2009 Jun 15;182(12):7482-9. doi: 10.4049/jimmunol.0802813.


High antigen levels do not preclude B-cell tolerance induction to alpha1,3-Gal via mixed chimerism.

Haspot F, Bardwell PD, Zhao G, Sykes M.

Xenotransplantation. 2008 Sep-Oct;15(5):313-20. doi: 10.1111/j.1399-3089.2008.00487.x.


B-cell extrinsic CR1/CR2 promotes natural antibody production and tolerance induction of anti-alphaGAL-producing B-1 cells.

Shimizu I, Kawahara T, Haspot F, Bardwell PD, Carroll MC, Sykes M.

Blood. 2007 Feb 15;109(4):1773-81. Epub 2006 Oct 5.


Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification.

Li Z, Scherer SJ, Ronai D, Iglesias-Ussel MD, Peled JU, Bardwell PD, Zhuang M, Lee K, Martin A, Edelmann W, Scharff MD.

J Exp Med. 2004 Jul 5;200(1):47-59.


Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice.

Bardwell PD, Woo CJ, Wei K, Li Z, Martin A, Sack SZ, Parris T, Edelmann W, Scharff MD.

Nat Immunol. 2004 Feb;5(2):224-9. Epub 2004 Jan 11.


Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination.

Martin A, Li Z, Lin DP, Bardwell PD, Iglesias-Ussel MD, Edelmann W, Scharff MD.

J Exp Med. 2003 Oct 20;198(8):1171-8.


Mutation detection of immunoglobulin V-regions by DHPLC.

Bardwell PD, Martin A, Scharff MD.

J Immunol Methods. 2002 Aug 1;266(1-2):165-73.


Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas.

Martin A, Bardwell PD, Woo CJ, Fan M, Shulman MJ, Scharff MD.

Nature. 2002 Feb 14;415(6873):802-6. Epub 2002 Jan 30.


Testing the reverse transcriptase model of somatic mutation.

Sack SZ, Bardwell PD, Scharff MD.

Mol Immunol. 2001 Aug;38(4):303-11.


Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line.

Zhang W, Bardwell PD, Woo CJ, Poltoratsky V, Scharff MD, Martin A.

Int Immunol. 2001 Sep;13(9):1175-84.


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