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Items: 3

1.

An oxidative DNA "damage" and repair mechanism localized in the VEGF promoter is important for hypoxia-induced VEGF mRNA expression.

Pastukh V, Roberts JT, Clark DW, Bardwell GC, Patel M, Al-Mehdi AB, Borchert GM, Gillespie MN.

Am J Physiol Lung Cell Mol Physiol. 2015 Dec 1;309(11):L1367-75. doi: 10.1152/ajplung.00236.2015. Epub 2015 Oct 2.

2.

Perinuclear mitochondrial clustering creates an oxidant-rich nuclear domain required for hypoxia-induced transcription.

Al-Mehdi AB, Pastukh VM, Swiger BM, Reed DJ, Patel MR, Bardwell GC, Pastukh VV, Alexeyev MF, Gillespie MN.

Sci Signal. 2012 Jul 3;5(231):ra47. doi: 10.1126/scisignal.2002712.

3.

Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences.

Pastukh VM, Zhang L, Ruchko MV, Gorodnya O, Bardwell GC, Tuder RM, Gillespie MN.

Int J Chron Obstruct Pulmon Dis. 2011;6:209-17. doi: 10.2147/COPD.S15922. Epub 2011 Mar 13.

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