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Items: 1 to 50 of 131

1.

Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library.

Merkouris S, Barde YA, Binley KE, Allen ND, Stepanov AV, Wu NC, Grande G, Lin CW, Li M, Nan X, Chacon-Fernandez P, DiStefano PS, Lindsay RM, Lerner RA, Xie J.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7023-E7032. doi: 10.1073/pnas.1806660115. Epub 2018 Jul 9.

2.

Measuring and Validating the Levels of Brain-Derived Neurotrophic Factor in Human Serum.

Naegelin Y, Dingsdale H, Säuberli K, Schädelin S, Kappos L, Barde YA.

eNeuro. 2018 Mar 22;5(2). pii: ENEURO.0419-17.2018. doi: 10.1523/ENEURO.0419-17.2018. eCollection 2018 Mar-Apr.

3.

Scaling pain threshold with microRNAs.

Cassels L, Barde YA.

Science. 2017 Jun 16;356(6343):1124-1125. doi: 10.1126/science.aan6784. No abstract available.

PMID:
28619901
4.

Brain-derived neurotrophic factor prevents dendritic retraction of adult mouse retinal ganglion cells.

Binley KE, Ng WS, Barde YA, Song B, Morgan JE.

Eur J Neurosci. 2016 Aug;44(3):2028-39. doi: 10.1111/ejn.13295. Epub 2016 Jul 19.

5.

Brain-derived Neurotrophic Factor in Megakaryocytes.

Chacón-Fernández P, Säuberli K, Colzani M, Moreau T, Ghevaert C, Barde YA.

J Biol Chem. 2016 May 6;291(19):9872-81. doi: 10.1074/jbc.M116.720029. Epub 2016 Mar 22.

6.

Astrocyte reactivity after brain injury-: The role of galectins 1 and 3.

Sirko S, Irmler M, Gascón S, Bek S, Schneider S, Dimou L, Obermann J, De Souza Paiva D, Poirier F, Beckers J, Hauck SM, Barde YA, Götz M.

Glia. 2015 Dec;63(12):2340-61. doi: 10.1002/glia.22898. Epub 2015 Aug 6.

7.

Cell biology in neuroscience: Death of developing neurons: new insights and implications for connectivity.

Dekkers MP, Nikoletopoulou V, Barde YA.

J Cell Biol. 2013 Nov 11;203(3):385-93. doi: 10.1083/jcb.201306136. Review.

8.

Developmental biology. Programmed cell death in neuronal development.

Dekkers MP, Barde YA.

Science. 2013 Apr 5;340(6128):39-41. doi: 10.1126/science.1236152. No abstract available.

PMID:
23559240
9.

Seizure-induced neuronal death is suppressed in the absence of the endogenous lectin Galectin-1.

Bischoff V, Deogracias R, Poirier F, Barde YA.

J Neurosci. 2012 Oct 31;32(44):15590-600. doi: 10.1523/JNEUROSCI.4983-11.2012.

10.

Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome.

Deogracias R, Yazdani M, Dekkers MP, Guy J, Ionescu MC, Vogt KE, Barde YA.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14230-5. doi: 10.1073/pnas.1206093109. Epub 2012 Aug 13.

11.

Disease modeling using embryonic stem cells: MeCP2 regulates nuclear size and RNA synthesis in neurons.

Yazdani M, Deogracias R, Guy J, Poot RA, Bird A, Barde YA.

Stem Cells. 2012 Oct;30(10):2128-39. doi: 10.1002/stem.1180.

12.

Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state.

Tiwari VK, Burger L, Nikoletopoulou V, Deogracias R, Thakurela S, Wirbelauer C, Kaut J, Terranova R, Hoerner L, Mielke C, Boege F, Murr R, Peters AH, Barde YA, Schübeler D.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):E934-43. doi: 10.1073/pnas.1119798109. Epub 2012 Apr 2.

13.

BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons.

Dieni S, Matsumoto T, Dekkers M, Rauskolb S, Ionescu MS, Deogracias R, Gundelfinger ED, Kojima M, Nestel S, Frotscher M, Barde YA.

J Cell Biol. 2012 Mar 19;196(6):775-88. doi: 10.1083/jcb.201201038. Epub 2012 Mar 12.

14.

[Save or kill - the ambivalence of neurotrophin receptors].

Bischoff V, Nikoletopoulou V, Barde YA.

Med Sci (Paris). 2011 Feb;27(2):119-21. doi: 10.1051/medsci/2011272119. Epub 2011 Mar 8. French. No abstract available.

15.

Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not.

Nikoletopoulou V, Lickert H, Frade JM, Rencurel C, Giallonardo P, Zhang L, Bibel M, Barde YA.

Nature. 2010 Sep 2;467(7311):59-63. doi: 10.1038/nature09336.

PMID:
20811452
16.

Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth.

Rauskolb S, Zagrebelsky M, Dreznjak A, Deogracias R, Matsumoto T, Wiese S, Erne B, Sendtner M, Schaeren-Wiemers N, Korte M, Barde YA.

J Neurosci. 2010 Feb 3;30(5):1739-49. doi: 10.1523/JNEUROSCI.5100-09.2010.

17.

Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma.

Pasutto F, Matsumoto T, Mardin CY, Sticht H, Brandstätter JH, Michels-Rautenstrauss K, Weisschuh N, Gramer E, Ramdas WD, van Koolwijk LM, Klaver CC, Vingerling JR, Weber BH, Kruse FE, Rautenstrauss B, Barde YA, Reis A.

Am J Hum Genet. 2009 Oct;85(4):447-56. doi: 10.1016/j.ajhg.2009.08.016. Epub 2009 Sep 17.

18.

Caution urged in trial of stem cells to treat spinal-cord injury.

Barde Y.

Nature. 2009 Mar 5;458(7234):29. doi: 10.1038/458029a. No abstract available.

PMID:
19262651
19.

Embryonic stem cell-derived neurons as a cellular system to study gene function: lack of amyloid precursor proteins APP and APLP2 leads to defective synaptic transmission.

Schrenk-Siemens K, Perez-Alcala S, Richter J, Lacroix E, Rahuel J, Korte M, Müller U, Barde YA, Bibel M.

Stem Cells. 2008 Aug;26(8):2153-63. doi: 10.1634/stemcells.2008-0010. Epub 2008 Jun 5.

20.

Neurotrophin receptor-mediated death of misspecified neurons generated from embryonic stem cells lacking Pax6.

Nikoletopoulou V, Plachta N, Allen ND, Pinto L, Götz M, Barde YA.

Cell Stem Cell. 2007 Nov;1(5):529-40. doi: 10.1016/j.stem.2007.08.011.

21.

Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF.

Matsumoto T, Rauskolb S, Polack M, Klose J, Kolbeck R, Korte M, Barde YA.

Nat Neurosci. 2008 Feb;11(2):131-3. doi: 10.1038/nn2038. Epub 2008 Jan 20.

PMID:
18204444
22.
23.

Self-renewal in the fly kidney.

Affolter M, Barde Y.

Dev Cell. 2007 Sep;13(3):321-2.

24.

Generation of a defined and uniform population of CNS progenitors and neurons from mouse embryonic stem cells.

Bibel M, Richter J, Lacroix E, Barde YA.

Nat Protoc. 2007;2(5):1034-43.

PMID:
17546008
25.

Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells.

Plachta N, Annaheim C, Bissière S, Lin S, Rüegg M, Hoving S, Müller D, Poirier F, Bibel M, Barde YA.

Nat Neurosci. 2007 Jun;10(6):712-9. Epub 2007 May 7.

PMID:
17486104
26.

The p75 neurotrophin receptor negatively modulates dendrite complexity and spine density in hippocampal neurons.

Zagrebelsky M, Holz A, Dechant G, Barde YA, Bonhoeffer T, Korte M.

J Neurosci. 2005 Oct 26;25(43):9989-99.

27.

The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus.

Rösch H, Schweigreiter R, Bonhoeffer T, Barde YA, Korte M.

Proc Natl Acad Sci U S A. 2005 May 17;102(20):7362-7. Epub 2005 May 9.

28.
29.

Developmental potential of defined neural progenitors derived from mouse embryonic stem cells.

Plachta N, Bibel M, Tucker KL, Barde YA.

Development. 2004 Nov;131(21):5449-56. Epub 2004 Oct 6.

30.

Differentiation of mouse embryonic stem cells into a defined neuronal lineage.

Bibel M, Richter J, Schrenk K, Tucker KL, Staiger V, Korte M, Goetz M, Barde YA.

Nat Neurosci. 2004 Sep;7(9):1003-9.

PMID:
15332090
31.

Death of injured neurons caused by the precursor of nerve growth factor.

Barde YA.

Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5703-4. Epub 2004 Apr 12. No abstract available.

32.

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.

Andorfer C, Kress Y, Espinoza M, de Silva R, Tucker KL, Barde YA, Duff K, Davies P.

J Neurochem. 2003 Aug;86(3):582-90.

33.

The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system.

Dechant G, Barde YA.

Nat Neurosci. 2002 Nov;5(11):1131-6. Review.

PMID:
12404007
34.

Neurobiology: neurotrophin channels excitement.

Barde YA.

Nature. 2002 Oct 17;419(6908):683-4. No abstract available.

PMID:
12384684
35.

Tau EGFP embryonic stem cells: an efficient tool for neuronal lineage selection and transplantation.

Wernig M, Tucker KL, Gornik V, Schneiders A, Buschwald R, Wiestler OD, Barde YA, Brüstle O.

J Neurosci Res. 2002 Sep 15;69(6):918-24.

PMID:
12205684
36.

Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons.

Naumann T, Casademunt E, Hollerbach E, Hofmann J, Dechant G, Frotscher M, Barde YA.

J Neurosci. 2002 Apr 1;22(7):2409-18.

37.

Glial cells generate neurons: the role of the transcription factor Pax6.

Heins N, Malatesta P, Cecconi F, Nakafuku M, Tucker KL, Hack MA, Chapouton P, Barde YA, Götz M.

Nat Neurosci. 2002 Apr;5(4):308-15. Erratum in: Nat Neurosci 2002 May;5(5):500.

PMID:
11896398
38.

Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a rho-dependent mechanism.

Neumann H, Schweigreiter R, Yamashita T, Rosenkranz K, Wekerle H, Barde YA.

J Neurosci. 2002 Feb 1;22(3):854-62.

39.
40.

A novel 7-transmembrane receptor expressed in nerve growth factor-dependent sensory neurons.

Friedel RH, Stubbusch J, Barde YA, Schnürch H.

Mol Cell Neurosci. 2001 Jan;17(1):31-40.

PMID:
11161467
41.

Neurotrophins are required for nerve growth during development.

Tucker KL, Meyer M, Barde YA.

Nat Neurosci. 2001 Jan;4(1):29-37.

PMID:
11135642
42.

Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system.

Bibel M, Barde YA.

Genes Dev. 2000 Dec 1;14(23):2919-37. Review. No abstract available.

43.

Neuronal and glial cell biology.

Barres BA, Barde Y.

Curr Opin Neurobiol. 2000 Oct;10(5):642-8. Review.

PMID:
11084327
44.
45.

Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth.

Yamashita T, Tucker KL, Barde YA.

Neuron. 1999 Nov;24(3):585-93.

46.

The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death.

Casademunt E, Carter BD, Benzel I, Frade JM, Dechant G, Barde YA.

EMBO J. 1999 Nov 1;18(21):6050-61.

47.

Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation.

Chen G, Kolbeck R, Barde YA, Bonhoeffer T, Kossel A.

J Neurosci. 1999 Sep 15;19(18):7983-90.

48.
49.

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