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Items: 15


Introduction: Physician-Scientists in the Evolving Landscape of Biomedical Research.

Lu LL, Kwon DS, Barczak AK.

J Infect Dis. 2018 Aug 14;218(suppl_1):S1-S2. doi: 10.1093/infdis/jiy105. No abstract available.


Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence.

Barczak AK, Avraham R, Singh S, Luo SS, Zhang WR, Bray MA, Hinman AE, Thompson M, Nietupski RM, Golas A, Montgomery P, Fitzgerald M, Smith RS, White DW, Tischler AD, Carpenter AE, Hung DT.

PLoS Pathog. 2017 May 15;13(5):e1006363. doi: 10.1371/journal.ppat.1006363. eCollection 2017 May.


Benzoic Acid-Inducible Gene Expression in Mycobacteria.

Dragset MS, Barczak AK, Kannan N, Mærk M, Flo TH, Valla S, Rubin EJ, Steigedal M.

PLoS One. 2015 Sep 8;10(9):e0134544. doi: 10.1371/journal.pone.0134544. eCollection 2015.


Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria.

Kieser KJ, Boutte CC, Kester JC, Baer CE, Barczak AK, Meniche X, Chao MC, Rego EH, Sassetti CM, Fortune SM, Rubin EJ.

PLoS Pathog. 2015 Jun 26;11(6):e1005010. doi: 10.1371/journal.ppat.1005010. eCollection 2015 Jun.


Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth.

Stanley SA, Barczak AK, Silvis MR, Luo SS, Sogi K, Vokes M, Bray MA, Carpenter AE, Moore CB, Siddiqi N, Rubin EJ, Hung DT.

PLoS Pathog. 2014 Feb 20;10(2):e1003946. doi: 10.1371/journal.ppat.1003946. eCollection 2014 Feb.


RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities.

Barczak AK, Gomez JE, Kaufmann BB, Hinson ER, Cosimi L, Borowsky ML, Onderdonk AB, Stanley SA, Kaur D, Bryant KF, Knipe DM, Sloutsky A, Hung DT.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6217-22. doi: 10.1073/pnas.1119540109. Epub 2012 Apr 2.


Productive steps toward an antimicrobial targeting virulence.

Barczak AK, Hung DT.

Curr Opin Microbiol. 2009 Oct;12(5):490-6. doi: 10.1016/j.mib.2009.06.012. Epub 2009 Jul 22. Review.


Hypervirulent M. tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak-Stat pathway.

Manca C, Tsenova L, Freeman S, Barczak AK, Tovey M, Murray PJ, Barry C, Kaplan G.

J Interferon Cytokine Res. 2005 Nov;25(11):694-701.


In vivo phenotypic dominance in mouse mixed infections with Mycobacterium tuberculosis clinical isolates.

Barczak AK, Domenech P, Boshoff HI, Reed MB, Manca C, Kaplan G, Barry CE 3rd.

J Infect Dis. 2005 Aug 15;192(4):600-6. Epub 2005 Jul 7.


A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response.

Reed MB, Domenech P, Manca C, Su H, Barczak AK, Kreiswirth BN, Kaplan G, Barry CE 3rd.

Nature. 2004 Sep 2;431(7004):84-7.


Regulation of tumor necrosis factor alpha gene expression by mycobacteria involves the assembly of a unique enhanceosome dependent on the coactivator proteins CBP/p300.

Barthel R, Tsytsykova AV, Barczak AK, Tsai EY, Dascher CC, Brenner MB, Goldfeld AE.

Mol Cell Biol. 2003 Jan;23(2):526-33.


A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo.

Tsai EY, Falvo JV, Tsytsykova AV, Barczak AK, Reimold AM, Glimcher LH, Fenton MJ, Gordon DC, Dunn IF, Goldfeld AE.

Mol Cell Biol. 2000 Aug;20(16):6084-94.


Molecular characterization of human brain N-acetylated alpha-linked acidic dipeptidase (NAALADase).

Luthi-Carter R, Barczak AK, Speno H, Coyle JT.

J Pharmacol Exp Ther. 1998 Aug;286(2):1020-5.


Hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) by cloned human glutamate carboxypeptidase II.

Luthi-Carter R, Barczak AK, Speno H, Coyle JT.

Brain Res. 1998 Jun 8;795(1-2):341-8.


Isolation and expression of a rat brain cDNA encoding glutamate carboxypeptidase II.

Luthi-Carter R, Berger UV, Barczak AK, Enna M, Coyle JT.

Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3215-20.

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