Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 107


Estimates of the 2015 global and regional disease burden from four foodborne metals - arsenic, cadmium, lead and methylmercury.

Gibb HJ, Barchowsky A, Bellinger D, Bolger PM, Carrington C, Havelaar AH, Oberoi S, Zang Y, O'Leary K, Devleesschauwer B.

Environ Res. 2019 Jul;174:188-194. doi: 10.1016/j.envres.2018.12.062. Epub 2018 Dec 25.


Klotho: An Elephant in Aging Research.

Cheikhi A, Barchowsky A, Sahu A, Shinde SN, Pius A, Clemens ZJ, Li H, Kennedy CA, Hoeck JD, Franti M, Ambrosio F.

J Gerontol A Biol Sci Med Sci. 2019 Jun 18;74(7):1031-1042. doi: 10.1093/gerona/glz061.


Global burden of cancer and coronary heart disease resulting from dietary exposure to arsenic, 2015.

Oberoi S, Devleesschauwer B, Gibb HJ, Barchowsky A.

Environ Res. 2019 Apr;171:185-192. doi: 10.1016/j.envres.2019.01.025. Epub 2019 Jan 11.


Mitochondria are a substrate of cellular memory.

Cheikhi A, Wallace C, St Croix C, Cohen C, Tang WY, Wipf P, Benos PV, Ambrosio F, Barchowsky A.

Free Radic Biol Med. 2019 Jan;130:528-541. doi: 10.1016/j.freeradbiomed.2018.11.028. Epub 2018 Nov 22.


Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration.

Sahu A, Mamiya H, Shinde SN, Cheikhi A, Winter LL, Vo NV, Stolz D, Roginskaya V, Tang WY, St Croix C, Sanders LH, Franti M, Van Houten B, Rando TA, Barchowsky A, Ambrosio F.

Nat Commun. 2018 Nov 19;9(1):4859. doi: 10.1038/s41467-018-07253-3.


A dose-response meta-analysis of chronic arsenic exposure and incident cardiovascular disease.

Moon KA, Oberoi S, Barchowsky A, Chen Y, Guallar E, Nachman KE, Rahman M, Sohel N, D'Ippoliti D, Wade TJ, James KA, Farzan SF, Karagas MR, Ahsan H, Navas-Acien A.

Int J Epidemiol. 2018 Apr 25. doi: 10.1093/ije/dyy073. [Epub ahead of print] No abstract available.


A dose-response meta-analysis of chronic arsenic exposure and incident cardiovascular disease.

Moon KA, Oberoi S, Barchowsky A, Chen Y, Guallar E, Nachman KE, Rahman M, Sohel N, D'Ippoliti D, Wade TJ, James KA, Farzan SF, Karagas MR, Ahsan H, Navas-Acien A.

Int J Epidemiol. 2017 Dec 1;46(6):1924-1939. doi: 10.1093/ije/dyx202. Review. Erratum in: Int J Epidemiol. 2018 Apr 25;:.


Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion.

Stearns-Reider KM, D'Amore A, Beezhold K, Rothrauff B, Cavalli L, Wagner WR, Vorp DA, Tsamis A, Shinde S, Zhang C, Barchowsky A, Rando TA, Tuan RS, Ambrosio F.

Aging Cell. 2017 Jun;16(3):518-528. doi: 10.1111/acel.12578. Epub 2017 Mar 30.


Regulation of cyclin D1 by arsenic and microRNA inhibits adipogenesis.

Beezhold K, Klei LR, Barchowsky A.

Toxicol Lett. 2017 Jan 4;265:147-155. doi: 10.1016/j.toxlet.2016.12.002. Epub 2016 Dec 5.


Arsenic Promotes NF-Κb-Mediated Fibroblast Dysfunction and Matrix Remodeling to Impair Muscle Stem Cell Function.

Zhang C, Ferrari R, Beezhold K, Stearns-Reider K, D'Amore A, Haschak M, Stolz D, Robbins PD, Barchowsky A, Ambrosio F.

Stem Cells. 2016 Mar;34(3):732-42. doi: 10.1002/stem.2232. Epub 2016 Jan 8. Erratum in: Stem Cells. 2016 Sep;34(9):2448.


Arsenic induces structural and compositional colonic microbiome change and promotes host nitrogen and amino acid metabolism.

Dheer R, Patterson J, Dudash M, Stachler EN, Bibby KJ, Stolz DB, Shiva S, Wang Z, Hazen SL, Barchowsky A, Stolz JF.

Toxicol Appl Pharmacol. 2015 Dec 15;289(3):397-408. doi: 10.1016/j.taap.2015.10.020. Epub 2015 Oct 31.


Letter to the editor on "Exposure to hazardous air pollutants and the risk of amyotrophic lateral sclerosis".

Malek AM, Barchowsky A, Bowser R, Heiman-Patterson T, Lacomis D, Rana S, Youk A, Talbott EO.

Environ Pollut. 2015 Dec;207:432-3. doi: 10.1016/j.envpol.2015.05.014. Epub 2015 May 19. No abstract available.


Exposure to hazardous air pollutants and the risk of amyotrophic lateral sclerosis.

Malek AM, Barchowsky A, Bowser R, Heiman-Patterson T, Lacomis D, Rana S, Ada Youk, Talbott EO.

Environ Pollut. 2015 Feb;197:181-186. doi: 10.1016/j.envpol.2014.12.010. Epub 2014 Dec 23.


Role of magnesium ions on osteogenic response in bone marrow stromal cells.

Yoshizawa S, Brown A, Barchowsky A, Sfeir C.

Connect Tissue Res. 2014 Aug;55 Suppl 1:155-9. doi: 10.3109/03008207.2014.923877.


Arsenic induces sustained impairment of skeletal muscle and muscle progenitor cell ultrastructure and bioenergetics.

Ambrosio F, Brown E, Stolz D, Ferrari R, Goodpaster B, Deasy B, Distefano G, Roperti A, Cheikhi A, Garciafigueroa Y, Barchowsky A.

Free Radic Biol Med. 2014 Sep;74:64-73. doi: 10.1016/j.freeradbiomed.2014.06.012. Epub 2014 Jun 21.


The global burden of disease for skin, lung, and bladder cancer caused by arsenic in food.

Oberoi S, Barchowsky A, Wu F.

Cancer Epidemiol Biomarkers Prev. 2014 Jul;23(7):1187-94. doi: 10.1158/1055-9965.EPI-13-1317. Epub 2014 May 3.


Magnesium ion stimulation of bone marrow stromal cells enhances osteogenic activity, simulating the effect of magnesium alloy degradation.

Yoshizawa S, Brown A, Barchowsky A, Sfeir C.

Acta Biomater. 2014 Jun;10(6):2834-42. doi: 10.1016/j.actbio.2014.02.002. Epub 2014 Feb 7.


Environmental and occupational risk factors for amyotrophic lateral sclerosis: a case-control study.

Malek AM, Barchowsky A, Bowser R, Heiman-Patterson T, Lacomis D, Rana S, Youk A, Stickler D, Lackland DT, Talbott EO.

Neurodegener Dis. 2014;14(1):31-8. doi: 10.1159/000355344. Epub 2013 Nov 12.


Arsenic-stimulated lipolysis and adipose remodeling is mediated by G-protein-coupled receptors.

Garciafigueroa DY, Klei LR, Ambrosio F, Barchowsky A.

Toxicol Sci. 2013 Aug;134(2):335-44. doi: 10.1093/toxsci/kft108. Epub 2013 May 6.


Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic.

Cronican AA, Fitz NF, Carter A, Saleem M, Shiva S, Barchowsky A, Koldamova R, Schug J, Lefterov I.

PLoS One. 2013;8(2):e53478. doi: 10.1371/journal.pone.0053478. Epub 2013 Feb 6.


Arsenic activates endothelin-1 Gi protein-coupled receptor signaling to inhibit stem cell differentiation in adipogenesis.

Klei LR, Garciafigueroa DY, Barchowsky A.

Toxicol Sci. 2013 Feb;131(2):512-20. doi: 10.1093/toxsci/kfs323. Epub 2012 Nov 14.


Pesticide exposure as a risk factor for amyotrophic lateral sclerosis: a meta-analysis of epidemiological studies: pesticide exposure as a risk factor for ALS.

Malek AM, Barchowsky A, Bowser R, Youk A, Talbott EO.

Environ Res. 2012 Aug;117:112-9. doi: 10.1016/j.envres.2012.06.007. Epub 2012 Jul 20.


The Toxicology Education Summit: building the future of toxicology through education.

Barchowsky A, Buckley LA, Carlson GP, Fitsanakis VA, Ford SM, Genter MB, Germolec DR, Leavens TL, Lehman-McKeeman LD, Safe SH, Sulentic CE, Eidemiller BJ.

Toxicol Sci. 2012 Jun;127(2):331-8. doi: 10.1093/toxsci/kfs111. Epub 2012 Mar 29.


Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling.

Al Ghouleh I, Khoo NK, Knaus UG, Griendling KK, Touyz RM, Thannickal VJ, Barchowsky A, Nauseef WM, Kelley EE, Bauer PM, Darley-Usmar V, Shiva S, Cifuentes-Pagano E, Freeman BA, Gladwin MT, Pagano PJ.

Free Radic Biol Med. 2011 Oct 1;51(7):1271-88. doi: 10.1016/j.freeradbiomed.2011.06.011. Epub 2011 Jun 14. Review.


Arsenic toxicology: translating between experimental models and human pathology.

States JC, Barchowsky A, Cartwright IL, Reichard JF, Futscher BW, Lantz RC.

Environ Health Perspect. 2011 Oct;119(10):1356-63. doi: 10.1289/ehp.1103441. Epub 2011 Jun 17. Review.


Pulmonary endpoints (lung carcinomas and asbestosis) following inhalation exposure to asbestos.

Mossman BT, Lippmann M, Hesterberg TW, Kelsey KT, Barchowsky A, Bonner JC.

J Toxicol Environ Health B Crit Rev. 2011;14(1-4):76-121. doi: 10.1080/10937404.2011.556047. Review.


Multiple protein kinase pathways mediate amplified IL-6 release by human lung fibroblasts co-exposed to nickel and TLR-2 agonist, MALP-2.

Gao F, Brant KA, Ward RM, Cattley RT, Barchowsky A, Fabisiak JP.

Toxicol Appl Pharmacol. 2010 Sep 1;247(2):146-57. doi: 10.1016/j.taap.2010.06.007. Epub 2010 Jun 17.


The Werner syndrome protein suppresses telomeric instability caused by chromium (VI) induced DNA replication stress.

Liu FJ, Barchowsky A, Opresko PL.

PLoS One. 2010 Jun 16;5(6):e11152. doi: 10.1371/journal.pone.0011152.


Endothelial dysfunction and claudin 5 regulation during acrolein-induced lung injury.

Jang AS, Concel VJ, Bein K, Brant KA, Liu S, Pope-Varsalona H, Dopico RA Jr, Di YP, Knoell DL, Barchowsky A, Leikauf GD.

Am J Respir Cell Mol Biol. 2011 Apr;44(4):483-90. doi: 10.1165/rcmb.2009-0391OC. Epub 2010 Jun 4.


Chromium(VI) stimulates Fyn to initiate innate immune gene induction in human airway epithelial cells.

Nemec AA, Zubritsky LM, Barchowsky A.

Chem Res Toxicol. 2010 Feb 15;23(2):396-404. doi: 10.1021/tx900365u.


The Werner syndrome protein functions in repair of Cr(VI)-induced replication-associated DNA damage.

Liu FJ, Barchowsky A, Opresko PL.

Toxicol Sci. 2009 Aug;110(2):307-18. doi: 10.1093/toxsci/kfp104. Epub 2009 Jun 1.


Signal transducer and activator of transcription 1 (STAT1) is essential for chromium silencing of gene induction in human airway epithelial cells.

Nemec AA, Barchowsky A.

Toxicol Sci. 2009 Jul;110(1):212-23. doi: 10.1093/toxsci/kfp084. Epub 2009 Apr 29.


Arsenic requires sphingosine-1-phosphate type 1 receptors to induce angiogenic genes and endothelial cell remodeling.

Straub AC, Klei LR, Stolz DB, Barchowsky A.

Am J Pathol. 2009 May;174(5):1949-58. doi: 10.2353/ajpath.2009.081016. Epub 2009 Apr 6.


Surfactant-associated protein B is critical to survival in nickel-induced injury in mice.

Bein K, Wesselkamper SC, Liu X, Dietsch M, Majumder N, Concel VJ, Medvedovic M, Sartor MA, Henning LN, Venditto C, Borchers MT, Barchowsky A, Weaver TE, Tichelaar JW, Prows DR, Korfhagen TR, Hardie WD, Bachurski CJ, Leikauf GD.

Am J Respir Cell Mol Biol. 2009 Aug;41(2):226-36. doi: 10.1165/rcmb.2008-0317OC. Epub 2009 Jan 8.


Nickel mobilizes intracellular zinc to induce metallothionein in human airway epithelial cells.

Nemec AA, Leikauf GD, Pitt BR, Wasserloos KJ, Barchowsky A.

Am J Respir Cell Mol Biol. 2009 Jul;41(1):69-75. doi: 10.1165/rcmb.2008-0409OC. Epub 2008 Dec 18.


Arsenic-stimulated liver sinusoidal capillarization in mice requires NADPH oxidase-generated superoxide.

Straub AC, Clark KA, Ross MA, Chandra AG, Li S, Gao X, Pagano PJ, Stolz DB, Barchowsky A.

J Clin Invest. 2008 Dec;118(12):3980-9. doi: 10.1172/JCI35092. Epub 2008 Nov 13.


Arsenic and cardiovascular disease.

States JC, Srivastava S, Chen Y, Barchowsky A.

Toxicol Sci. 2009 Feb;107(2):312-23. doi: 10.1093/toxsci/kfn236. Epub 2008 Nov 17. Review.


NQO1, MPO, CYP2E1, GSTT1 and GSTM1 polymorphisms and biological effects of benzene exposure--a literature review.

Dougherty D, Garte S, Barchowsky A, Zmuda J, Taioli E.

Toxicol Lett. 2008 Nov 10;182(1-3):7-17. doi: 10.1016/j.toxlet.2008.09.008. Epub 2008 Sep 20. Review.


Angiogenic potential of 3-nitro-4-hydroxy benzene arsonic acid (roxarsone).

Basu P, Ghosh RN, Grove LE, Klei L, Barchowsky A.

Environ Health Perspect. 2008 Apr;116(4):520-3. doi: 10.1289/ehp.10885.


Positive signaling interactions between arsenic and ethanol for angiogenic gene induction in human microvascular endothelial cells.

Klei LR, Barchowsky A.

Toxicol Sci. 2008 Apr;102(2):319-27. doi: 10.1093/toxsci/kfn003. Epub 2008 Jan 8.


Sequential exposure to carbon nanotubes and bacteria enhances pulmonary inflammation and infectivity.

Shvedova AA, Fabisiak JP, Kisin ER, Murray AR, Roberts JR, Tyurina YY, Antonini JM, Feng WH, Kommineni C, Reynolds J, Barchowsky A, Castranova V, Kagan VE.

Am J Respir Cell Mol Biol. 2008 May;38(5):579-90. Epub 2007 Dec 20.


The vascular system as a target of metal toxicity.

Prozialeck WC, Edwards JR, Nebert DW, Woods JM, Barchowsky A, Atchison WD.

Toxicol Sci. 2008 Apr;102(2):207-18. Epub 2007 Oct 18. Review.


Hyperoxia enhances VEGF release from A549 cells via post-transcriptional processes.

Shenberger JS, Zhang L, Powell RJ, Barchowsky A.

Free Radic Biol Med. 2007 Sep 1;43(5):844-52. Epub 2007 Jun 6.


Identification of multiple MAPK-mediated transcription factors regulated by tobacco smoke in airway epithelial cells.

Zhao J, Harper R, Barchowsky A, Di YP.

Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L480-90. Epub 2007 May 11.


Arsenic stimulates sinusoidal endothelial cell capillarization and vessel remodeling in mouse liver.

Straub AC, Stolz DB, Ross MA, Hernández-Zavala A, Soucy NV, Klei LR, Barchowsky A.

Hepatology. 2007 Jan;45(1):205-12.


Low level arsenic promotes progressive inflammatory angiogenesis and liver blood vessel remodeling in mice.

Straub AC, Stolz DB, Vin H, Ross MA, Soucy NV, Klei LR, Barchowsky A.

Toxicol Appl Pharmacol. 2007 Aug 1;222(3):327-36. Epub 2006 Oct 24.


Cr(VI)-stimulated STAT3 tyrosine phosphorylation and nuclear translocation in human airway epithelial cells requires Lck.

O'Hara KA, Vaghjiani RJ, Nemec AA, Klei LR, Barchowsky A.

Biochem J. 2007 Mar 1;402(2):261-9.


Chromium (VI) inhibits heme oxygenase-1 expression in vivo and in arsenic-exposed human airway epithelial cells.

O'Hara KA, Nemec AA, Alam J, Klei LR, Mossman BT, Barchowsky A.

J Cell Physiol. 2006 Oct;209(1):113-21.


Neovascularization and angiogenic gene expression following chronic arsenic exposure in mice.

Soucy NV, Mayka D, Klei LR, Nemec AA, Bauer JA, Barchowsky A.

Cardiovasc Toxicol. 2005;5(1):29-41.


Hyperoxia alters the expression and phosphorylation of multiple factors regulating translation initiation.

Shenberger JS, Myers JL, Zimmer SG, Powell RJ, Barchowsky A.

Am J Physiol Lung Cell Mol Physiol. 2005 Mar;288(3):L442-9. Epub 2004 Nov 12.

Supplemental Content

Loading ...
Support Center