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Items: 11


Digestive Exophagy: Phagocyte digestion of objects too large for phagocytosis.

Maxfield FR, Barbosa-Lorenzi VC, Singh RK.

Traffic. 2019 Oct 30. doi: 10.1111/tra.12712. [Epub ahead of print] Review.


TLR4 (Toll-Like Receptor 4)-Dependent Signaling Drives Extracellular Catabolism of LDL (Low-Density Lipoprotein) Aggregates.

Singh RK, Haka AS, Asmal A, Barbosa-Lorenzi VC, Grosheva I, Chin HF, Xiong Y, Hla T, Maxfield FR.

Arterioscler Thromb Vasc Biol. 2019 Oct 10:ATVBAHA119313200. doi: 10.1161/ATVBAHA.119.313200. [Epub ahead of print]


Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity.

Coats BR, Schoenfelt KQ, Barbosa-Lorenzi VC, Peris E, Cui C, Hoffman A, Zhou G, Fernandez S, Zhai L, Hall BA, Haka AS, Shah AM, Reardon CA, Brady MJ, Rhodes CJ, Maxfield FR, Becker L.

Cell Rep. 2017 Sep 26;20(13):3149-3161. doi: 10.1016/j.celrep.2017.08.096.


Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages.

Wang Y, Subramanian M, Yurdagul A Jr, Barbosa-Lorenzi VC, Cai B, de Juan-Sanz J, Ryan TA, Nomura M, Maxfield FR, Tabas I.

Cell. 2017 Oct 5;171(2):331-345.e22. doi: 10.1016/j.cell.2017.08.041. Epub 2017 Sep 21.


Stigmasterol prevents glucolipotoxicity induced defects in glucose-stimulated insulin secretion.

Ward MG, Li G, Barbosa-Lorenzi VC, Hao M.

Sci Rep. 2017 Aug 25;7(1):9536. doi: 10.1038/s41598-017-10209-0.


Curdlan induces selective mast cell degranulation without concomitant release of LTC4, IL-6 or CCL2.

Barbosa-Lorenzi VC, Peyda S, Scheynius A, Nilsson G, Lunderius-Andersson C.

Immunobiology. 2017 Apr;222(4):647-650. doi: 10.1016/j.imbio.2016.12.001. Epub 2016 Dec 6.


Recombinant ArtinM activates mast cells.

Barbosa-Lorenzi VC, Cecilio NT, de Almeida Buranello PA, Pranchevicius MC, Goldman MH, Pereira-da-Silva G, Roque-Barreira MC, Jamur MC, Oliver C.

BMC Immunol. 2016 Jul 4;17(1):22. doi: 10.1186/s12865-016-0161-0.


Exocytosis of macrophage lysosomes leads to digestion of apoptotic adipocytes and foam cell formation.

Haka AS, Barbosa-Lorenzi VC, Lee HJ, Falcone DJ, Hudis CA, Dannenberg AJ, Maxfield FR.

J Lipid Res. 2016 Jun;57(6):980-92. doi: 10.1194/jlr.M064089. Epub 2016 Apr 4.


Degradation of aggregated LDL occurs in complex extracellular sub-compartments of the lysosomal synapse.

Singh RK, Barbosa-Lorenzi VC, Lund FW, Grosheva I, Maxfield FR, Haka AS.

J Cell Sci. 2016 Mar 1;129(5):1072-82. doi: 10.1242/jcs.181743. Epub 2016 Jan 22.


Phospholipase D2 Modulates the Secretory Pathway in RBL-2H3 Mast Cells.

Marchini-Alves CM, Barbosa Lorenzi VC, da Silva EZ, Mazucato VM, Jamur MC, Oliver C.

PLoS One. 2015 Oct 22;10(10):e0139888. doi: 10.1371/journal.pone.0139888. eCollection 2015.


The lectin ArtinM binds to mast cells inducing cell activation and mediator release.

Barbosa-Lorenzi VC, Buranello PA, Roque-Barreira MC, Jamur MC, Oliver C, Pereira-da-Silva G.

Biochem Biophys Res Commun. 2011 Dec 16;416(3-4):318-24. doi: 10.1016/j.bbrc.2011.11.033. Epub 2011 Nov 15.

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