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Items: 46

1.

Missense variants in NOX1 and p22phox in a case of very-early-onset inflammatory bowel disease are functionally linked to NOD2.

Lipinski S, Petersen BS, Barann M, Piecyk A, Tran F, Mayr G, Jentzsch M, Aden K, Stengel ST, Klostermeier UC, Sheth V, Ellinghaus D, Rausch T, Korbel JO, Nothnagel M, Krawczak M, Gilissen C, Veltman JA, Forster M, Forster P, Lee CC, Fritscher-Ravens A, Schreiber S, Franke A, Rosenstiel P.

Cold Spring Harb Mol Case Stud. 2019 Feb 1;5(1). pii: a002428. doi: 10.1101/mcs.a002428. Print 2019 Feb.

2.

Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters.

Behjati Ardakani F, Kattler K, Nordström K, Gasparoni N, Gasparoni G, Fuchs S, Sinha A, Barann M, Ebert P, Fischer J, Hutter B, Zipprich G, Imbusch CD, Felder B, Eils J, Brors B, Lengauer T, Manke T, Rosenstiel P, Walter J, Schulz MH.

Epigenetics Chromatin. 2018 Nov 10;11(1):66. doi: 10.1186/s13072-018-0236-7.

3.

Manananggal - a novel viewer for alternative splicing events.

Barann M, Zimmer R, Birzele F.

BMC Bioinformatics. 2017 Feb 21;18(1):120. doi: 10.1186/s12859-017-1548-5.

4.

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.

Schmidt F, Gasparoni N, Gasparoni G, Gianmoena K, Cadenas C, Polansky JK, Ebert P, Nordström K, Barann M, Sinha A, Fröhler S, Xiong J, Dehghani Amirabad A, Behjati Ardakani F, Hutter B, Zipprich G, Felder B, Eils J, Brors B, Chen W, Hengstler JG, Hamann A, Lengauer T, Rosenstiel P, Walter J, Schulz MH.

Nucleic Acids Res. 2017 Jan 9;45(1):54-66. doi: 10.1093/nar/gkw1061. Epub 2016 Nov 29.

5.

Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease.

Häsler R, Sheibani-Tezerji R, Sinha A, Barann M, Rehman A, Esser D, Aden K, Knecht C, Brandt B, Nikolaus S, Schäuble S, Kaleta C, Franke A, Fretter C, Müller W, Hütt MT, Krawczak M, Schreiber S, Rosenstiel P.

Gut. 2017 Dec;66(12):2087-2097. doi: 10.1136/gutjnl-2016-311651. Epub 2016 Sep 30.

6.

Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing.

Ferreira PG, Oti M, Barann M, Wieland T, Ezquina S, Friedländer MR, Rivas MA, Esteve-Codina A; GEUVADIS Consortium, Rosenstiel P, Strom TM, Lappalainen T, Guigó R, Sammeth M.

Sci Rep. 2016 Sep 12;6:32406. doi: 10.1038/srep32406.

7.

Epigenetic dynamics of monocyte-to-macrophage differentiation.

Wallner S, Schröder C, Leitão E, Berulava T, Haak C, Beißer D, Rahmann S, Richter AS, Manke T, Bönisch U, Arrigoni L, Fröhler S, Klironomos F, Chen W, Rajewsky N, Müller F, Ebert P, Lengauer T, Barann M, Rosenstiel P, Gasparoni G, Nordström K, Walter J, Brors B, Zipprich G, Felder B, Klein-Hitpass L, Attenberger C, Schmitz G, Horsthemke B.

Epigenetics Chromatin. 2016 Jul 29;9:33. doi: 10.1186/s13072-016-0079-z. eCollection 2016.

8.

Fast and slow interactions of n-alkanols with human 5-HT3A receptors: Implications for anesthetic mechanisms.

Decker AM, Witten S, Barann M, Urban BW.

Biochim Biophys Acta. 2015 Jul;1848(7):1524-35. doi: 10.1016/j.bbamem.2015.03.032. Epub 2015 Apr 8.

9.

Effects of opioids on human serotonin transporters.

Barann M, Stamer UM, Lyutenska M, Stüber F, Bönisch H, Urban B.

Naunyn Schmiedebergs Arch Pharmacol. 2015 Jan;388(1):43-9. doi: 10.1007/s00210-014-1056-3. Epub 2014 Oct 22.

PMID:
25332055
10.

Transcriptome and genome sequencing uncovers functional variation in humans.

Lappalainen T, Sammeth M, Friedländer MR, 't Hoen PA, Monlong J, Rivas MA, Gonzàlez-Porta M, Kurbatova N, Griebel T, Ferreira PG, Barann M, Wieland T, Greger L, van Iterson M, Almlöf J, Ribeca P, Pulyakhina I, Esser D, Giger T, Tikhonov A, Sultan M, Bertier G, MacArthur DG, Lek M, Lizano E, Buermans HP, Padioleau I, Schwarzmayr T, Karlberg O, Ongen H, Kilpinen H, Beltran S, Gut M, Kahlem K, Amstislavskiy V, Stegle O, Pirinen M, Montgomery SB, Donnelly P, McCarthy MI, Flicek P, Strom TM; Geuvadis Consortium, Lehrach H, Schreiber S, Sudbrak R, Carracedo A, Antonarakis SE, Häsler R, Syvänen AC, van Ommen GJ, Brazma A, Meitinger T, Rosenstiel P, Guigó R, Gut IG, Estivill X, Dermitzakis ET.

Nature. 2013 Sep 26;501(7468):506-11. doi: 10.1038/nature12531. Epub 2013 Sep 15.

11.

Which agonist properties are important for the activation of 5-HT3A receptors?

Meiboom MF, Barann M, Witten S, Groeneveld K, Urban BW.

Biochim Biophys Acta. 2013 Nov;1828(11):2564-73. doi: 10.1016/j.bbamem.2013.06.013. Epub 2013 Jun 18.

12.

Janus--a comprehensive tool investigating the two faces of transcription.

Barann M, Esser D, Klostermeier UC, Lappalainen T, Luzius A, Kuiper JW, Ammerpohl O, Vater I, Siebert R, Amstislavskiy V, Sudbrak R, Lehrach H, Schreiber S, Rosenstiel P.

Bioinformatics. 2013 Jul 1;29(13):1600-6. doi: 10.1093/bioinformatics/btt185. Epub 2013 Apr 24.

PMID:
23620359
13.

Base-pair resolution DNA methylome of the EBV-positive Endemic Burkitt lymphoma cell line DAUDI determined by SOLiD bisulfite-sequencing.

Kreck B, Richter J, Ammerpohl O, Barann M, Esser D, Petersen BS, Vater I, Murga Penas EM, Bormann Chung CA, Seisenberger S, Lee Boyd V, Smallwood S, Drexler HG, Macleod RA, Hummel M, Krueger F, Häsler R, Schreiber S, Rosenstiel P, Franke A, Siebert R.

Leukemia. 2013 Aug;27(8):1751-3. doi: 10.1038/leu.2013.4. Epub 2013 Jan 11. No abstract available.

14.

From next-generation sequencing alignments to accurate comparison and validation of single-nucleotide variants: the pibase software.

Forster M, Forster P, Elsharawy A, Hemmrich G, Kreck B, Wittig M, Thomsen I, Stade B, Barann M, Ellinghaus D, Petersen BS, May S, Melum E, Schilhabel MB, Keller A, Schreiber S, Rosenstiel P, Franke A.

Nucleic Acids Res. 2013 Jan 7;41(1):e16. doi: 10.1093/nar/gks836. Epub 2012 Sep 10.

15.

Next-generation RNA sequencing reveals differential expression of MYCN target genes and suggests the mTOR pathway as a promising therapy target in MYCN-amplified neuroblastoma.

Schramm A, Köster J, Marschall T, Martin M, Schwermer M, Fielitz K, Büchel G, Barann M, Esser D, Rosenstiel P, Rahmann S, Eggert A, Schulte JH.

Int J Cancer. 2013 Feb 1;132(3):E106-15. doi: 10.1002/ijc.27787. Epub 2012 Sep 26.

16.

A powerful method for transcriptional profiling of specific cell types in eukaryotes: laser-assisted microdissection and RNA sequencing.

Schmid MW, Schmidt A, Klostermeier UC, Barann M, Rosenstiel P, Grossniklaus U.

PLoS One. 2012;7(1):e29685. doi: 10.1371/journal.pone.0029685. Epub 2012 Jan 26.

17.

A tissue-specific landscape of sense/antisense transcription in the mouse intestine.

Klostermeier UC, Barann M, Wittig M, Häsler R, Franke A, Gavrilova O, Kreck B, Sina C, Schilhabel MB, Schreiber S, Rosenstiel P.

BMC Genomics. 2011 Jun 10;12:305. doi: 10.1186/1471-2164-12-305.

18.

Maternal epigenetic pathways control parental contributions to Arabidopsis early embryogenesis.

Autran D, Baroux C, Raissig MT, Lenormand T, Wittig M, Grob S, Steimer A, Barann M, Klostermeier UC, Leblanc O, Vielle-Calzada JP, Rosenstiel P, Grimanelli D, Grossniklaus U.

Cell. 2011 May 27;145(5):707-19. doi: 10.1016/j.cell.2011.04.014.

19.

Antagonistic effects of ondansetron and tramadol? A randomized placebo and active drug controlled study.

Rauers NI, Stüber F, Lee EH, Musshoff F, Fimmers R, Barann M, Stamer UM.

J Pain. 2010 Dec;11(12):1274-81. doi: 10.1016/j.jpain.2010.03.003. Epub 2010 May 21.

PMID:
20488759
20.

Characterization of the naturally occurring Arg344His variant of the human 5-HT 3A receptor.

Combrink S, Kostanian A, Walstab J, Barann M, Brüss M, Göthert M, Bönisch H.

Pharmacol Rep. 2009 Sep-Oct;61(5):785-97.

21.

Cloning, characterisation, and comparative quantitative expression analyses of receptor for advanced glycation end products (RAGE) transcript forms.

Sterenczak KA, Willenbrock S, Barann M, Klemke M, Soller JT, Eberle N, Nolte I, Bullerdiek J, Murua Escobar H.

Gene. 2009 Apr 1;434(1-2):35-42. doi: 10.1016/j.gene.2008.10.027. Epub 2008 Nov 12.

PMID:
19061941
22.

The effects of fentanyl-like opioids and hydromorphone on human 5-HT3A receptors.

Wittmann M, Schaaf T, Peters I, Wirz S, Urban BW, Barann M.

Anesth Analg. 2008 Jul;107(1):107-12. doi: 10.1213/ane.0b013e31817342c2.

PMID:
18635474
23.

Molecular actions of propofol on human 5-HT3A receptors: enhancement as well as inhibition by closely related phenol derivatives.

Barann M, Linden I, Witten S, Urban BW.

Anesth Analg. 2008 Mar;106(3):846-57, table of contents. doi: 10.1213/ane.0b013e318162ca7c.

PMID:
18292429
24.

The effects of morphine on human 5-HT3A receptors.

Wittmann M, Peters I, Schaaf T, Wartenberg HC, Wirz S, Nadstawek J, Urban BW, Barann M.

Anesth Analg. 2006 Sep;103(3):747-52.

PMID:
16931691
25.

Interactions of anesthetics with their targets: non-specific, specific or both?

Urban BW, Bleckwenn M, Barann M.

Pharmacol Ther. 2006 Sep;111(3):729-70. Epub 2006 Feb 14. Review.

PMID:
16483665
26.

Effects of tramadol and O-demethyl-tramadol on human 5-HT reuptake carriers and human 5-HT3A receptors: a possible mechanism for tramadol-induced early emesis.

Barann M, Urban B, Stamer U, Dorner Z, Bönisch H, Brüss M.

Eur J Pharmacol. 2006 Feb 15;531(1-3):54-8. Epub 2006 Jan 19.

PMID:
16427041
27.

Interactions of metoclopramide and ergotamine with human 5-HT(3A) receptors and human 5-HT reuptake carriers.

Walkembach J, Brüss M, Urban BW, Barann M.

Br J Pharmacol. 2005 Oct;146(4):543-52. Erratum in: Br J Pharmacol. 2005 Dec;146(8):1156.

28.

Pharmacological and electrophysiological properties of the naturally occurring Pro391Arg variant of the human 5-HT3A receptor.

Kurzwelly D, Barann M, Kostanian A, Combrink S, Bönisch H, Göthert M, Brüss M.

Pharmacogenetics. 2004 Mar;14(3):165-72.

PMID:
15167704
29.

Influence of sodium substitutes on 5-HT-mediated effects at mouse 5-HT3 receptors.

Barann M, Schmidt K, Göthert M, Urban BW, Bönisch H.

Br J Pharmacol. 2004 Jun;142(3):501-8. Epub 2004 May 17.

30.

Direct inhibition by cannabinoids of human 5-HT3A receptors: probable involvement of an allosteric modulatory site.

Barann M, Molderings G, Brüss M, Bönisch H, Urban BW, Göthert M.

Br J Pharmacol. 2002 Nov;137(5):589-96.

31.
32.

Modified 5-HT3A receptor function by co-expression of alternatively spliced human 5-HT3A receptor isoforms.

Brüss M, Barann M, Hayer-Zillgen M, Eucker T, Göthert M, Bönisch H.

Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362(4-5):392-401.

PMID:
11111833
33.

Recombinant human 5-HT3A receptors in outside-out patches of HEK 293 cells: basic properties and barbiturate effects.

Barann M, Meder W, Dorner Z, Brüss M, Bönisch H, Göthert M, Urban BW.

Naunyn Schmiedebergs Arch Pharmacol. 2000 Sep;362(3):255-65.

PMID:
10997728
34.

Loss of propofol during in vitro experiments.

Barann M, Friederich P, Retzmann K, Dybek A, Urban BW.

Anesthesiology. 2000 Jul;93(1):310-1. No abstract available.

PMID:
10861191
35.

Inhibition of 5-HT3 receptors by propofol: equilibrium and kinetic measurements.

Barann M, Dilger JP, Bönisch H, Göthert M, Dybek A, Urban BW.

Neuropharmacology. 2000 Apr 3;39(6):1064-74.

PMID:
10727717
36.
37.

Interactions of general anesthetics within the pore of an ion channel.

Barann M, Wenningmann I, Dilger JP.

Toxicol Lett. 1998 Nov 23;100-101:155-61. Review.

PMID:
10049136
38.

Inhibition by propofol of 5-HT3 receptors in excised patches of NIE-115 cells.

Barann M, Bönisch H, Urban BW, Göthert M.

Ann N Y Acad Sci. 1998 Dec 15;861:278-9. No abstract available.

PMID:
9928289
39.

Inhibition of 5-HT3 receptor cation channels by ifenprodil in excised patches of N1E-115 cells.

Barann M, Bönisch H, Urban BW, Göthert M.

Naunyn Schmiedebergs Arch Pharmacol. 1998 Aug;358(2):145-52.

PMID:
9749998
40.

5-HT3 receptors in outside-out patches of N1E-115 neuroblastoma cells: basic properties and effects of pentobarbital.

Barann M, Göthert M, Bönisch H, Dybek A, Urban BW.

Neuropharmacology. 1997 Apr-May;36(4-5):655-64.

PMID:
9225291
41.

Mechanisms of barbiturate inhibition of acetylcholine receptor channels.

Dilger JP, Boguslavsky R, Barann M, Katz T, Vidal AM.

J Gen Physiol. 1997 Mar;109(3):401-14.

42.

Increasing effect of ethanol on 5-HT3 receptor-mediated 14C-guanidinium influx in N1E-115 neuroblastoma cells.

Barann M, Ruppert K, Göthert M, Bönisch H.

Naunyn Schmiedebergs Arch Pharmacol. 1995 Aug;352(2):149-56.

PMID:
7477437
43.

5-HT3 receptor antagonism by anpirtoline, a mixed 5-HT1 receptor agonist/5-HT3 receptor antagonist.

Göthert M, Hamon M, Barann M, Bönisch H, Gozlan H, Laguzzi R, Metzenauer P, Nickel B, Szelenyi I.

Br J Pharmacol. 1995 Jan;114(2):269-74.

44.
45.
46.

Cross-tolerance to L-arginine-dependent guanylate cyclase activators in nitrate-tolerant LLC-PK1 kidney epithelial cells.

Schröder H, Barann M, Bennett BM, Leitman DC.

Pol J Pharmacol Pharm. 1990 May-Jun;42(3):259-63.

PMID:
1979870

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