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Items: 16


Transition of the prion protein from a structured cellular form (PrPC ) to the infectious scrapie agent (PrPSc ).

Baral PK, Yin J, Aguzzi A, James MNG.

Protein Sci. 2019 Dec;28(12):2055-2063. doi: 10.1002/pro.3735. Epub 2019 Oct 25. Review.


Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion.

Baral PK, Swayampakula M, Aguzzi A, James MNG.

FEBS J. 2018 May;285(9):1701-1714. doi: 10.1111/febs.14438. Epub 2018 Apr 14.


X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.

Baral PK, Swayampakula M, Aguzzi A, James MN.

J Struct Biol. 2015 Oct;192(1):37-47. doi: 10.1016/j.jsb.2015.08.014. Epub 2015 Aug 28.


Structural basis of prion inhibition by phenothiazine compounds.

Baral PK, Swayampakula M, Rout MK, Kav NN, Spyracopoulos L, Aguzzi A, James MN.

Structure. 2014 Feb 4;22(2):291-303. doi: 10.1016/j.str.2013.11.009. Epub 2013 Dec 26.


Phosphorylation status of 72 kDa MMP-2 determines its structure and activity in response to peroxynitrite.

Jacob-Ferreira AL, Kondo MY, Baral PK, James MN, Holt A, Fan X, Schulz R.

PLoS One. 2013 Aug 27;8(8):e71794. doi: 10.1371/journal.pone.0071794. eCollection 2013.


The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.

Sonati T, Reimann RR, Falsig J, Baral PK, O'Connor T, Hornemann S, Yaganoglu S, Li B, Herrmann US, Wieland B, Swayampakula M, Rahman MH, Das D, Kav N, Riek R, Liberski PP, James MN, Aguzzi A.

Nature. 2013 Sep 5;501(7465):102-6. doi: 10.1038/nature12402. Epub 2013 Jul 31.


The crystal structure of an octapeptide repeat of the prion protein in complex with a Fab fragment of the POM2 antibody.

Swayampakula M, Baral PK, Aguzzi A, Kav NN, James MN.

Protein Sci. 2013 Jul;22(7):893-903. doi: 10.1002/pro.2270. Epub 2013 May 31.


Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1.

Baral PK, Wieland B, Swayampakula M, Polymenidou M, Rahman MH, Kav NN, Aguzzi A, James MN.

Acta Crystallogr D Biol Crystallogr. 2012 Nov;68(Pt 11):1501-12. doi: 10.1107/S0907444912037328. Epub 2012 Oct 18.


Crystallization and preliminary X-ray diffraction analysis of prion protein bound to the Fab fragment of the POM1 antibody.

Baral PK, Wieland B, Swayampakula M, Polymenidou M, Aguzzi A, Kav NN, James MN.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Oct 1;67(Pt 10):1211-3. doi: 10.1107/S1744309111026273. Epub 2011 Sep 24.


Site-directed mutagenesis of histidine 69 and glutamic acid 148 alters the ribonuclease activity of pea ABR17 (PR10.4).

Krishnaswamy S, Baral PK, James MN, Kav NN.

Plant Physiol Biochem. 2011 Sep;49(9):958-62. doi: 10.1016/j.plaphy.2010.10.010. Epub 2011 May 4.


Role of the general base Glu-268 in nitroglycerin bioactivation and superoxide formation by aldehyde dehydrogenase-2.

Wenzl MV, Beretta M, Gorren AC, Zeller A, Baral PK, Gruber K, Russwurm M, Koesling D, Schmidt K, Mayer B.

J Biol Chem. 2009 Jul 24;284(30):19878-86. doi: 10.1074/jbc.M109.005652. Epub 2009 Jun 8.


The first structure of dipeptidyl-peptidase III provides insight into the catalytic mechanism and mode of substrate binding.

Baral PK, Jajcanin-Jozić N, Deller S, Macheroux P, Abramić M, Gruber K.

J Biol Chem. 2008 Aug 8;283(32):22316-24. doi: 10.1074/jbc.M803522200. Epub 2008 Jun 10.


Structure-function correlations of two highly conserved motifs in Saccharomyces cerevisiae squalene epoxidase.

Ruckenstuhl C, Poschenel A, Possert R, Baral PK, Gruber K, Turnowsky F.

Antimicrob Agents Chemother. 2008 Apr;52(4):1496-9. doi: 10.1128/AAC.01282-07. Epub 2008 Jan 22.


Characterization of squalene epoxidase of Saccharomyces cerevisiae by applying terbinafine-sensitive variants.

Ruckenstuhl C, Lang S, Poschenel A, Eidenberger A, Baral PK, Kohút P, Hapala I, Gruber K, Turnowsky F.

Antimicrob Agents Chemother. 2007 Jan;51(1):275-84. Epub 2006 Oct 16.


Efficacy of methotrexate in rheumatoid arthritis.

Ali ML, Alam MN, Haq SA, Das KK, Baral PK.

Bangladesh Med Res Counc Bull. 1997 Dec;23(3):72-6.


Efficacy of ciprofloxacin in enteric fever: comparison of treatment duration in sensitive and multidrug-resistant Salmonella.

Alam MN, Haq SA, Das KK, Baral PK, Mazid MN, Siddique RU, Rahman KM, Hasan Z, Khan MA, Dutta P.

Am J Trop Med Hyg. 1995 Sep;53(3):306-11.


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