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Augmented hydrolysis of acid pretreated sugarcane bagasse by PEG 6000 addition: a case study of Cellic CTec2 with recycling and reuse.

Baral P, Jain L, Kurmi AK, Kumar V, Agrawal D.

Bioprocess Biosyst Eng. 2019 Nov 8. doi: 10.1007/s00449-019-02241-3. [Epub ahead of print]


Monitoring steady production of 1,3-propanediol during bioprospecting of glycerol-assimilating soil microbiome using dye-based pH-stat method.

Garg R, Baral P, Jain L, Kurmi AK, Agrawal D.

J Appl Microbiol. 2019 Oct 22. doi: 10.1111/jam.14496. [Epub ahead of print]


Transition of the prion protein from a structured cellular form (PrPC ) to the infectious scrapie agent (PrPSc ).

Baral PK, Yin J, Aguzzi A, James MNG.

Protein Sci. 2019 Dec;28(12):2055-2063. doi: 10.1002/pro.3735. Epub 2019 Oct 25. Review.


Conformational Flexibility of the Protein-Protein Interfaces of the Ebola Virus VP40 Structural Matrix Filament.

Pavadai E, Bhattarai N, Baral P, Stahelin RV, Chapagain PP, Gerstman BS.

J Phys Chem B. 2019 Oct 31;123(43):9045-9053. doi: 10.1021/acs.jpcb.9b04674. Epub 2019 Oct 16.


Designing Scientific Advisory Committees for a Complex World.

Hoffman SJ, Ottersen T, Baral P, Fafard P.

Glob Chall. 2018 Sep 27;2(9):1800075. doi: 10.1002/gch2.201800075. eCollection 2018 Sep. No abstract available.


A case of hyperventilation leading to apnea and desaturation in PACU.

Thapa P, Subedi A, Poudel A, Baral P.

BMC Anesthesiol. 2019 Aug 14;19(1):152. doi: 10.1186/s12871-019-0827-2.


Temperature and oxygen related ecophysiological traits of snow trout (Schizothorax richardsonii) are sensitive to seasonal changes in a Himalayan stream environment.

Kamalam BS, Mahija J, Baral P, Pandey A, Akhtar MS, Ciji A, Rajesh M.

J Therm Biol. 2019 Jul;83:22-29. doi: 10.1016/j.jtherbio.2019.04.014. Epub 2019 Apr 21.


Liposomal Bupivacaine Enhances the Pain-Control Benefits of Uniportal Thoracoscopic Lobectomy.

Louis SG, King C, Baral P, Veeramachaneni N.

Ann Thorac Surg. 2019 Nov;108(5):1514-1518. doi: 10.1016/j.athoracsur.2019.04.095. Epub 2019 Jun 20.


Molecular mechanisms of pore formation and membrane disruption by the antimicrobial lantibiotic peptide Mutacin 1140.

Pokhrel R, Bhattarai N, Baral P, Gerstman BS, Park JH, Handfield M, Chapagain PP.

Phys Chem Chem Phys. 2019 Jun 21;21(23):12530-12539. doi: 10.1039/c9cp01558b. Epub 2019 May 31.


Pain and immunity: implications for host defence.

Baral P, Udit S, Chiu IM.

Nat Rev Immunol. 2019 Jul;19(7):433-447. doi: 10.1038/s41577-019-0147-2. Review.


Characteristics Associated With Mortality in 372 Patients Receiving Low-Dose Recombinant Factor VIIa (rFVIIa) for Cardiac Surgical Bleeding.

Baral P, Cotter E, Gao G, He J, Wirtz K, Sharma A, Zorn Iii T, Muehlebach G, Flynn B.

J Cardiothorac Vasc Anesth. 2019 Aug;33(8):2133-2140. doi: 10.1053/j.jvca.2019.01.047. Epub 2019 Jan 22.


CXCL1 regulates neutrophil homeostasis in pneumonia-derived sepsis caused by Streptococcus pneumoniae serotype 3.

Paudel S, Baral P, Ghimire L, Bergeron S, Jin L, DeCorte JA, Le JT, Cai S, Jeyaseelan S.

Blood. 2019 Mar 21;133(12):1335-1345. doi: 10.1182/blood-2018-10-878082. Epub 2019 Feb 5.


Towards a Systematic Understanding of How to Institutionally Design Scientific Advisory Committees: A Conceptual Framework and Introduction to a Special Journal Issue.

Hoffman SJ, Ottersen T, Tejpar A, Baral P, Fafard P.

Glob Chall. 2018 Sep 27;2(9):1800020. doi: 10.1002/gch2.201800020. eCollection 2018 Sep. Review.


What Can Be Learned from Experience with Scientific Advisory Committees in the Field of International Environmental Politics?

Andresen S, Baral P, Hoffman SJ, Fafard P.

Glob Chall. 2018 Aug 5;2(9):1800055. doi: 10.1002/gch2.201800055. eCollection 2018 Sep. Review.


An Overview of Systematic Reviews to Inform the Institutional Design of Scientific Advisory Committees.

Behdinan A, Gunn E, Baral P, Sritharan L, Fafard P, Hoffman SJ.

Glob Chall. 2018 Aug 8;2(9):1800019. doi: 10.1002/gch2.201800019. eCollection 2018 Sep. Review.


Outcomes for potential kidney transplant recipients offered public health service increased risk kidneys: A single-center experience.

Fernandez HE, Chiles MC, Pereira M, Husain SA, Miko B, Baral P, Dale LA, Patel S, Runge B, Tsapepas D, Sandoval PR, Ratner LE, Cohen DJ, Mohan S.

Clin Transplant. 2018 Dec;32(12):e13427. doi: 10.1111/ctr.13427. Epub 2018 Nov 8.


NLRC4 suppresses IL-17A-mediated neutrophil-dependent host defense through upregulation of IL-18 and induction of necroptosis during Gram-positive pneumonia.

Paudel S, Ghimire L, Jin L, Baral P, Cai S, Jeyaseelan S.

Mucosal Immunol. 2019 Jan;12(1):247-257. doi: 10.1038/s41385-018-0088-2. Epub 2018 Oct 2.


NLRP6 negatively regulates pulmonary host defense in Gram-positive bacterial infection through modulating neutrophil recruitment and function.

Ghimire L, Paudel S, Jin L, Baral P, Cai S, Jeyaseelan S.

PLoS Pathog. 2018 Sep 24;14(9):e1007308. doi: 10.1371/journal.ppat.1007308. eCollection 2018 Sep.


Author Correction: Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia.

Baral P, Umans BD, Li L, Wallrapp A, Bist M, Kirschbaum T, Wei Y, Zhou Y, Kuchroo VK, Burkett PR, Yipp BG, Liberles SD, Chiu IM.

Nat Med. 2018 Oct;24(10):1625-1626. doi: 10.1038/s41591-018-0093-8.


Bacteriological profile and antibiotic susceptibility of neonatal sepsis in neonatal intensive care unit of a tertiary hospital in Nepal.

Pokhrel B, Koirala T, Shah G, Joshi S, Baral P.

BMC Pediatr. 2018 Jun 27;18(1):208. doi: 10.1186/s12887-018-1176-x.


Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion.

Baral PK, Swayampakula M, Aguzzi A, James MNG.

FEBS J. 2018 May;285(9):1701-1714. doi: 10.1111/febs.14438. Epub 2018 Apr 14.


Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia.

Baral P, Umans BD, Li L, Wallrapp A, Bist M, Kirschbaum T, Wei Y, Zhou Y, Kuchroo VK, Burkett PR, Yipp BG, Liberles SD, Chiu IM.

Nat Med. 2018 May;24(4):417-426. doi: 10.1038/nm.4501. Epub 2018 Mar 5. Erratum in: Nat Med. 2018 Oct;24(10):1625-1626.


Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314.

Blake KJ, Baral P, Voisin T, Lubkin A, Pinho-Ribeiro FA, Adams KL, Roberson DP, Ma YC, Otto M, Woolf CJ, Torres VJ, Chiu IM.

Nat Commun. 2018 Jan 2;9(1):37. doi: 10.1038/s41467-017-02448-6.


Erratum: The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.

Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VK.

Nature. 2017 Nov 30;551(7682):658. doi: 10.1038/nature24480. Epub 2017 Nov 15.


The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.

Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VK.

Nature. 2017 Sep 21;549(7672):351-356. doi: 10.1038/nature24029. Epub 2017 Sep 13. Erratum in: Nature. 2017 Nov 15;:.


Weight-based contrast administration in the computerized tomography evaluation of acute pulmonary embolism: Challenges in optimizing imaging quality.

Laurent L, Zamfirova I, Sulo S, Baral P.

Medicine (Baltimore). 2017 Feb;96(5):e5972. doi: 10.1097/MD.0000000000005972.


Estimation of Stature from Nasal Length.

Shrestha RN, Banstola D, Nepal D, Baral P.

JNMA J Nepal Med Assoc. 2016 Oct-Dec;55(204):76-78.


Pain and Itch: Beneficial or Harmful to Antimicrobial Defense?

Baral P, Mills K, Pinho-Ribeiro FA, Chiu IM.

Cell Host Microbe. 2016 Jun 8;19(6):755-9. doi: 10.1016/j.chom.2016.05.010.


Cigarette Smoke Extract-Exposed Methicillin-Resistant Staphylococcus aureus Regulates Leukocyte Function for Pulmonary Persistence.

Kulkarni R, Caskey J, Singh SK, Paudel S, Baral P, Schexnayder M, Kim J, Kim N, Kosmider B, Ratner AJ, Jeyaseelan S.

Am J Respir Cell Mol Biol. 2016 Oct;55(4):586-601.


X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.

Baral PK, Swayampakula M, Aguzzi A, James MN.

J Struct Biol. 2015 Oct;192(1):37-47. doi: 10.1016/j.jsb.2015.08.014. Epub 2015 Aug 28.


Effectiveness of an oral cholera vaccine campaign to prevent clinically-significant cholera in Odisha State, India.

Wierzba TF, Kar SK, Mogasale VV, Kerketta AS, You YA, Baral P, Khuntia HK, Ali M, Kim YH, Rath SB, Bhattachan A, Sah B.

Vaccine. 2015 May 15;33(21):2463-9. doi: 10.1016/j.vaccine.2015.03.073. Epub 2015 Apr 4.


Evaluation of antibacterial activity of some traditionally used medicinal plants against human pathogenic bacteria.

Marasini BP, Baral P, Aryal P, Ghimire KR, Neupane S, Dahal N, Singh A, Ghimire L, Shrestha K.

Biomed Res Int. 2015;2015:265425. doi: 10.1155/2015/265425. Epub 2015 Feb 9.


Biometric parameters and intra ocular lens power used for cataract eyes in Karnali, Nepal.

Baral P, Baral N, Maharjan IM, Gautam BR, Bhandari M.

Nepal J Ophthalmol. 2014 Jul-Dec;6(2):192-6. doi: 10.3126/nepjoph.v6i2.11690.


Surgical Results of Non-small Cell Lung Cancer in Nepal.

Thakur B, Yonghui D, Devkota M, Poudel B, Baral P.

JNMA J Nepal Med Assoc. 2014 Oct-Dec;52(196):992-6.


Divergent functions of Toll-like receptors during bacterial lung infections.

Baral P, Batra S, Zemans RL, Downey GP, Jeyaseelan S.

Am J Respir Crit Care Med. 2014 Oct 1;190(7):722-32. doi: 10.1164/rccm.201406-1101PP. Review.


Prevalence of Occlusal Traits in the Deciduous Dentition of Children of Kaski District, Nepal.

Baral P, Budathoki P, Bhuju KG, Koirala B.

JNMA J Nepal Med Assoc. 2014 Jul-Sep;52(195):862-5.


Geohelminths: public health significance.

Ojha SC, Jaide C, Jinawath N, Rotjanapan P, Baral P.

J Infect Dev Ctries. 2014 Jan 15;8(1):5-16. doi: 10.3855/jidc.3183. Review.


Activation of NADPH oxidase is essential, but not sufficient, in controlling intracellular multiplication of Burkholderia pseudomallei in primary human monocytes.

Wikraiphat C, Pudla M, Baral P, Kitthawee S, Utaisincharoen P.

Pathog Dis. 2014 Jun;71(1):69-72. doi: 10.1111/2049-632X.12122. Epub 2014 Jan 22.


Structural basis of prion inhibition by phenothiazine compounds.

Baral PK, Swayampakula M, Rout MK, Kav NN, Spyracopoulos L, Aguzzi A, James MN.

Structure. 2014 Feb 4;22(2):291-303. doi: 10.1016/j.str.2013.11.009. Epub 2013 Dec 26.


Phosphorylation status of 72 kDa MMP-2 determines its structure and activity in response to peroxynitrite.

Jacob-Ferreira AL, Kondo MY, Baral PK, James MN, Holt A, Fan X, Schulz R.

PLoS One. 2013 Aug 27;8(8):e71794. doi: 10.1371/journal.pone.0071794. eCollection 2013.


The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.

Sonati T, Reimann RR, Falsig J, Baral PK, O'Connor T, Hornemann S, Yaganoglu S, Li B, Herrmann US, Wieland B, Swayampakula M, Rahman MH, Das D, Kav N, Riek R, Liberski PP, James MN, Aguzzi A.

Nature. 2013 Sep 5;501(7465):102-6. doi: 10.1038/nature12402. Epub 2013 Jul 31.


The crystal structure of an octapeptide repeat of the prion protein in complex with a Fab fragment of the POM2 antibody.

Swayampakula M, Baral PK, Aguzzi A, Kav NN, James MN.

Protein Sci. 2013 Jul;22(7):893-903. doi: 10.1002/pro.2270. Epub 2013 May 31.


Clinical and microbiological observational study on AmpC β-lactamase-producing Enterobacteriaceae in a hospital of Nepal.

Baral P, Neupane S, Shrestha B, Ghimire KR, Marasini BP, Lekhak B.

Braz J Infect Dis. 2013 Mar-Apr;17(2):256-9. doi: 10.1016/j.bjid.2012.09.012. Epub 2013 Feb 27.


Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1.

Baral PK, Wieland B, Swayampakula M, Polymenidou M, Rahman MH, Kav NN, Aguzzi A, James MN.

Acta Crystallogr D Biol Crystallogr. 2012 Nov;68(Pt 11):1501-12. doi: 10.1107/S0907444912037328. Epub 2012 Oct 18.


High prevalence of multidrug resistance in bacterial uropathogens from Kathmandu, Nepal.

Baral P, Neupane S, Marasini BP, Ghimire KR, Lekhak B, Shrestha B.

BMC Res Notes. 2012 Jan 19;5:38. doi: 10.1186/1756-0500-5-38.


Crystallization and preliminary X-ray diffraction analysis of prion protein bound to the Fab fragment of the POM1 antibody.

Baral PK, Wieland B, Swayampakula M, Polymenidou M, Aguzzi A, Kav NN, James MN.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Oct 1;67(Pt 10):1211-3. doi: 10.1107/S1744309111026273. Epub 2011 Sep 24.

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