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Sarcopenia: A Time for Action. An SCWD Position Paper.

Bauer J, Morley JE, Schols AMWJ, Ferrucci L, Cruz-Jentoft AJ, Dent E, Baracos VE, Crawford JA, Doehner W, Heymsfield SB, Jatoi A, Kalantar-Zadeh K, Lainscak M, Landi F, Laviano A, Mancuso M, Muscaritoli M, Prado CM, Strasser F, von Haehling S, Coats AJS, Anker SD.

J Cachexia Sarcopenia Muscle. 2019 Sep 15. doi: 10.1002/jcsm.12483. [Epub ahead of print]


Immunohistochemical phenotyping of T cells, granulocytes, and phagocytes in the muscle of cancer patients: association with radiologically defined muscle mass and gene expression.

Anoveros-Barrera A, Bhullar AS, Stretch C, Dunichand-Hoedl AR, Martins KJB, Rieger A, Bigam D, McMullen T, Bathe OF, Putman CT, Field CJ, Baracos VE, Mazurak VC.

Skelet Muscle. 2019 Sep 14;9(1):24. doi: 10.1186/s13395-019-0209-y.


Skeletal muscle mass correlates with increased toxicity during neoadjuvant radiochemotherapy in locally advanced esophageal cancer: A SAKK 75/08 substudy.

Panje CM, Höng L, Hayoz S, Baracos VE, Herrmann E, Garcia Schüler H, Meier UR, Henke G, Schacher S, Hawle H, Gérard MA, Ruhstaller T, Plasswilm L; Swiss Group for Clinical Cancer Research (SAKK).

Radiat Oncol. 2019 Sep 11;14(1):166. doi: 10.1186/s13014-019-1372-3.


Accuracy of Resting Energy Expenditure Predictive Equations in Patients With Cancer.

Purcell SA, Elliott SA, Baracos VE, Chu QSC, Sawyer MB, Mourtzakis M, Easaw JC, Spratlin JL, Siervo M, Prado CM.

Nutr Clin Pract. 2019 Jul 25. doi: 10.1002/ncp.10374. [Epub ahead of print]


Clinical and biological characterization of skeletal muscle tissue biopsies of surgical cancer patients.

Anoveros-Barrera A, Bhullar AS, Stretch C, Esfandiari N, Dunichand-Hoedl AR, Martins KJB, Bigam D, Khadaroo RG, McMullen T, Bathe OF, Damaraju S, Skipworth RJ, Putman CT, Baracos VE, Mazurak VC.

J Cachexia Sarcopenia Muscle. 2019 Jul 15. doi: 10.1002/jcsm.12466. [Epub ahead of print]


Rapid atrophy of cardiac left ventricular mass in patients with non-small cell carcinoma of the lung.

Kazemi-Bajestani SMR, Becher H, Butts C, Basappa NS, Smylie M, Joy AA, Sangha R, Gallivan A, Kavsak P, Chu Q, Baracos VE.

J Cachexia Sarcopenia Muscle. 2019 Jul 10. doi: 10.1002/jcsm.12451. [Epub ahead of print]


Profiling Determinants of Resting Energy Expenditure in Colorectal Cancer.

Purcell SA, Baracos VE, Chu QSC, Sawyer MB, Severin D, Mourtzakis M, Lieffers JR, Prado CM.

Nutr Cancer. 2019 Jul 8:1-8. doi: 10.1080/01635581.2019.1635172. [Epub ahead of print]


Proceedings of the Canadian Frailty Network Workshop: Identifying Biomarkers of Frailty to Support Frailty Risk Assessment, Diagnosis and Prognosis. Toronto, January 15, 2018.

Muscedere J, Kim PM, Afilalo J, Balion C, Baracos VE, Bowdish D, Cesari M, Erusalimsky JD, Fülöp T, Heckman G, Howlett SE, Khadaroo RG, Kirkland JL, Rodriguez Mañas L, Marzetti E, Paré G, Raina P, Rockwood K, Sinclair A, Skappak C, Verschoor C, Walter S.

J Frailty Aging. 2019;8(3):106-116. doi: 10.14283/jfa.2019.12.


Change in Skeletal Muscle Following Resection of Stage I-III Colorectal Cancer is Predictive of Poor Survival: A Cohort Study.

Hopkins JJ, Reif R, Bigam D, Baracos VE, Eurich DT, Sawyer MM.

World J Surg. 2019 Oct;43(10):2518-2526. doi: 10.1007/s00268-019-05054-3.


Muscle segmentation in axial computed tomography (CT) images at the lumbar (L3) and thoracic (T4) levels for body composition analysis.

Dabiri S, Popuri K, Cespedes Feliciano EM, Caan BJ, Baracos VE, Beg MF.

Comput Med Imaging Graph. 2019 Jul;75:47-55. doi: 10.1016/j.compmedimag.2019.04.007. Epub 2019 May 9.


Convergent neuronal projections from paraventricular nucleus, parabrachial nucleus, and brainstem onto gastrocnemius muscle, white and brown adipose tissue in male rats.

Doslikova B, Tchir D, McKinty A, Zhu X, Marks DL, Baracos VE, Colmers WF.

J Comp Neurol. 2019 May 2. doi: 10.1002/cne.24710. [Epub ahead of print]


Dietary patterns and their relationships to sarcopenia in Portuguese patients with gastrointestinal cancer: An exploratory study.

Velho S, Moço S, Ferreira A, Cruz R, Agostinho L, Cabral MS, Luz G, Lopes F, Teixeira JA, Strecht J, Coelho JLP, Maio R, Cravo M, Baracos VE.

Nutrition. 2019 Jul - Aug;63-64:193-199. doi: 10.1016/j.nut.2019.01.014. Epub 2019 Jan 25.


Cancer-Associated Malnutrition and CT-Defined Sarcopenia and Myosteatosis Are Endemic in Overweight and Obese Patients.

Martin L, Gioulbasanis I, Senesse P, Baracos VE.

JPEN J Parenter Enteral Nutr. 2019 Apr 22. doi: 10.1002/jpen.1597. [Epub ahead of print]


Prevalence and prognostic significance of malnutrition in patients with cancers of the head and neck.

Kubrak C, Martin L, Gramlich L, Scrimger R, Jha N, Debenham B, Chua N, Walker J, Baracos VE.

Clin Nutr. 2019 Apr 4. pii: S0261-5614(19)30144-X. doi: 10.1016/j.clnu.2019.03.030. [Epub ahead of print]


Canadian Nutrition Society: Scientific Abstracts from the 10th Annual Scientific Meeting / Société canadienne de nutrition: Résumés scientifiques de la 10e réunion scientifique annuelle.

Nejatinamini S, Debenham B, Prado C, Baracos VE, Chu Q, Wismer WW, Mazurak VC.

Appl Physiol Nutr Metab. 2019 Apr;44(4 (Suppl. 1)):S1-S54. doi: 10.1139/apnm-2019-0152. No abstract available. Erratum in: Appl Physiol Nutr Metab. 2019 Jun;44(6):685.


Determinants of change in resting energy expenditure in patients with stage III/IV colorectal cancer.

Purcell SA, Wallengren O, Baracos VE, Lundholm K, Iresjö BM, Chu QSC, Ghosh SS, Prado CM.

Clin Nutr. 2019 Mar 30. pii: S0261-5614(19)30135-9. doi: 10.1016/j.clnu.2018.12.038. [Epub ahead of print]


The association of medical and demographic characteristics with sarcopenia and low muscle radiodensity in patients with nonmetastatic colorectal cancer.

Xiao J, Caan BJ, Cespedes Feliciano EM, Meyerhardt JA, Kroenke CH, Baracos VE, Weltzien E, Kwan ML, Alexeeff SE, Castillo AL, Prado CM.

Am J Clin Nutr. 2019 Mar 1;109(3):615-625. doi: 10.1093/ajcn/nqy328.


Low muscle mass is associated with early termination of chemotherapy related to toxicity in patients with head and neck cancer.

Sealy MJ, Dechaphunkul T, van der Schans CP, Krijnen WP, Roodenburg JLN, Walker J, Jager-Wittenaar H, Baracos VE.

Clin Nutr. 2019 Feb 22. pii: S0261-5614(19)30083-4. doi: 10.1016/j.clnu.2019.02.029. [Epub ahead of print]


The Impact of Muscle and Adipose Tissue on Long-term Survival in Patients With Stage I to III Colorectal Cancer.

Hopkins JJ, Reif RL, Bigam DL, Baracos VE, Eurich DT, Sawyer MB.

Dis Colon Rectum. 2019 May;62(5):549-560. doi: 10.1097/DCR.0000000000001352.


Cancer cachexia is defined by an ongoing loss of skeletal muscle mass.

Baracos VE, Mazurak VC, Bhullar AS.

Ann Palliat Med. 2019 Jan;8(1):3-12. doi: 10.21037/apm.2018.12.01. Review.


Undiagnosed cardiac deficits in non-small cell carcinoma patients in the candidate population for anti-cachexia clinical trials.

Kazemi-Bajestani SMR, Becher H, Butts C, Basappa NS, Smylie M, Joy AA, Sangha R, Gallivan A, Chu Q, Baracos VE.

Support Care Cancer. 2019 Apr;27(4):1551-1561. doi: 10.1007/s00520-018-4561-y. Epub 2018 Dec 13.


Host phenotype is associated with reduced survival independent of tumour biology in patients with colorectal liver metastases.

van Dijk DPJ, Krill M, Farshidfar F, Li T, Rensen SS, Olde Damink SWM, Dixon E, Sutherland FR, Ball CG, Mazurak VC, Baracos VE, Bathe OF.

J Cachexia Sarcopenia Muscle. 2019 Feb;10(1):123-130. doi: 10.1002/jcsm.12358. Epub 2018 Oct 31.


Poor Physical Function as a Marker of Sarcopenia in Adults with Class II/III Obesity.

Johnson Stoklossa CA, Ghosh SS, Forhan M, Sharma AM, Terada T, Siervo M, Baracos VE, Padwal RS, Hung PA, Sawyer MB, Maia YL, Prado CM.

Curr Dev Nutr. 2017 Dec 18;2(3):nzx008. doi: 10.3945/cdn.117.001743. eCollection 2018 Mar.


Assessing dietary intake in accordance with guidelines: Useful correlations with an ingesta-Verbal/Visual Analogue Scale in medical oncology patients.

Guerdoux-Ninot E, Flori N, Janiszewski C, Vaillé A, de Forges H, Raynard B, Baracos VE, Thezenas S, Senesse P.

Clin Nutr. 2019 Aug;38(4):1927-1935. doi: 10.1016/j.clnu.2018.06.974. Epub 2018 Jun 30.


A comparison of CT based measures of skeletal muscle mass and density from the Th4 and L3 levels in patients with advanced non-small-cell lung cancer.

Grønberg BH, Sjøblom B, Wentzel-Larsen T, Baracos VE, Hjermstad MJ, Aass N, Bremnes RM, Fløtten Ø, Bye A, Jordhøy M.

Eur J Clin Nutr. 2019 Jul;73(7):1069-1076. doi: 10.1038/s41430-018-0325-5. Epub 2018 Sep 25.


Cancer-associated malnutrition.

Baracos VE.

Eur J Clin Nutr. 2018 Sep;72(9):1255-1259. doi: 10.1038/s41430-018-0245-4. Epub 2018 Sep 5. Review. No abstract available.


Single-Nucleotide Polymorphisms in TAOK3 Are Associated With High Opioid Requirement for Pain Management in Patients With Advanced Cancer Admitted to a Tertiary Palliative Care Unit.

Gutteridge T, Kumaran M, Ghosh S, Fainsinger R, Klepstad P, Tarumi Y, Damaraju S, Baracos VE.

J Pain Symptom Manage. 2018 Oct;56(4):560-566. doi: 10.1016/j.jpainsymman.2018.07.011. Epub 2018 Jul 20.


Assessment of Computed Tomography (CT)-Defined Muscle and Adipose Tissue Features in Relation to Short-Term Outcomes After Elective Surgery for Colorectal Cancer: A Multicenter Approach.

Martin L, Hopkins J, Malietzis G, Jenkins JT, Sawyer MB, Brisebois R, MacLean A, Nelson G, Gramlich L, Baracos VE.

Ann Surg Oncol. 2018 Sep;25(9):2669-2680. doi: 10.1245/s10434-018-6652-x. Epub 2018 Jul 13.


Assessment of body composition and sarcopenia in patients with esophageal cancer: a systematic review and meta-analysis.

Boshier PR, Heneghan R, Markar SR, Baracos VE, Low DE.

Dis Esophagus. 2018 Aug 1;31(8). doi: 10.1093/dote/doy047. Review.


Systematic review and meta-analysis of the evidence for oral nutritional intervention on nutritional and clinical outcomes during chemo(radio)therapy: current evidence and guidance for design of future trials.

de van der Schueren MAE, Laviano A, Blanchard H, Jourdan M, Arends J, Baracos VE.

Ann Oncol. 2018 May 1;29(5):1141-1153. doi: 10.1093/annonc/mdy114.


Sarcopenia and myosteatosis are accompanied by distinct biological profiles in patients with pancreatic and periampullary adenocarcinomas.

Stretch C, Aubin JM, Mickiewicz B, Leugner D, Al-Manasra T, Tobola E, Salazar S, Sutherland FR, Ball CG, Dixon E, Vogel HJ, Damaraju S, Baracos VE, Bathe OF.

PLoS One. 2018 May 3;13(5):e0196235. doi: 10.1371/journal.pone.0196235. eCollection 2018.


Low subcutaneous adiposity associates with higher mortality in female patients with cirrhosis.

Ebadi M, Tandon P, Moctezuma-Velazquez C, Ghosh S, Baracos VE, Mazurak VC, Montano-Loza AJ.

J Hepatol. 2018 Sep;69(3):608-616. doi: 10.1016/j.jhep.2018.04.015. Epub 2018 Apr 28.


Barriers to cancer nutrition therapy: excess catabolism of muscle and adipose tissues induced by tumour products and chemotherapy.

Schiessel DL, Baracos VE.

Proc Nutr Soc. 2018 Nov;77(4):394-402. doi: 10.1017/S0029665118000186. Epub 2018 Apr 30. Review.


Associations of pre-existing co-morbidities with skeletal muscle mass and radiodensity in patients with non-metastatic colorectal cancer.

Xiao J, Caan BJ, Weltzien E, Cespedes Feliciano EM, Kroenke CH, Meyerhardt JA, Baracos VE, Kwan ML, Castillo AL, Prado CM.

J Cachexia Sarcopenia Muscle. 2018 Aug;9(4):654-663. doi: 10.1002/jcsm.12301. Epub 2018 Apr 19.


Head and Neck Cancer Patients Do Not Meet Recommended Intakes of Micronutrients without Consuming Fortified Products.

Nejatinamini S, Kubrak C, Álvarez-Camacho M, Baracos VE, Ghosh S, Wismer WV, Mazurak VC.

Nutr Cancer. 2018 Apr;70(3):474-482. doi: 10.1080/01635581.2018.1445767. Epub 2018 Mar 13.


Sarcopenic obesity: hidden muscle wasting and its impact for survival and complications of cancer therapy.

Baracos VE, Arribas L.

Ann Oncol. 2018 Feb 1;29(suppl_2):ii1-ii9. doi: 10.1093/annonc/mdx810.


Barriers to the Interpretation of Body Composition in Colorectal Cancer: A Review of the Methodological Inconsistency and Complexity of the CT-Defined Body Habitus.

Hopkins JJ, Skubleny D, Bigam DL, Baracos VE, Eurich DT, Sawyer MB.

Ann Surg Oncol. 2018 May;25(5):1381-1394. doi: 10.1245/s10434-018-6395-8. Epub 2018 Feb 27. Review.


Bridging the gap: are animal models consistent with clinical cancer cachexia?

Baracos VE.

Nat Rev Clin Oncol. 2018 Apr;15(4):197-198. doi: 10.1038/nrclinonc.2018.14. Epub 2018 Feb 6. No abstract available.


Cancer-associated cachexia.

Baracos VE, Martin L, Korc M, Guttridge DC, Fearon KCH.

Nat Rev Dis Primers. 2018 Jan 18;4:17105. doi: 10.1038/nrdp.2017.105. Review.


Visceral adiposity increases risk for hepatocellular carcinoma in male patients with cirrhosis and recurrence after liver transplant.

Montano-Loza AJ, Mazurak VC, Ebadi M, Meza-Junco J, Sawyer MB, Baracos VE, Kneteman N.

Hepatology. 2018 Mar;67(3):914-923. doi: 10.1002/hep.29578. Epub 2018 Jan 26.


Fish oil mitigates myosteatosis and improves chemotherapy efficacy in a preclinical model of colon cancer.

Almasud AA, Giles KH, Miklavcic JJ, Martins KJB, Baracos VE, Putman CT, Guan LL, Mazurak VC.

PLoS One. 2017 Aug 23;12(8):e0183576. doi: 10.1371/journal.pone.0183576. eCollection 2017.


Body Composition in Relation to Clinical Outcomes in Renal Cell Cancer: A Systematic Review and Meta-analysis.

Vrieling A, Kampman E, Knijnenburg NC, Mulders PF, Sedelaar JPM, Baracos VE, Kiemeney LA.

Eur Urol Focus. 2018 Apr;4(3):420-434. doi: 10.1016/j.euf.2016.11.009. Epub 2016 Dec 4.


Psoas as a sentinel muscle for sarcopenia: a flawed premise.

Baracos VE.

J Cachexia Sarcopenia Muscle. 2017 Aug;8(4):527-528. doi: 10.1002/jcsm.12221. Epub 2017 Jul 3. No abstract available.


The applicability of a weight loss grading system in cancer cachexia: a longitudinal analysis.

Vagnildhaug OM, Blum D, Wilcock A, Fayers P, Strasser F, Baracos VE, Hjermstad MJ, Kaasa S, Laird B, Solheim TS; European Palliative Care Cancer Symptom study group.

J Cachexia Sarcopenia Muscle. 2017 Oct;8(5):789-797. doi: 10.1002/jcsm.12220. Epub 2017 Jun 18.


Subcutaneous adiposity is an independent predictor of mortality in cancer patients.

Ebadi M, Martin L, Ghosh S, Field CJ, Lehner R, Baracos VE, Mazurak VC.

Br J Cancer. 2017 Jun 27;117(1):148-155. doi: 10.1038/bjc.2017.149. Epub 2017 Jun 6.


Muscle mass and association to quality of life in non-small cell lung cancer patients.

Bye A, Sjøblom B, Wentzel-Larsen T, Grønberg BH, Baracos VE, Hjermstad MJ, Aass N, Bremnes RM, Fløtten Ø, Jordhøy M.

J Cachexia Sarcopenia Muscle. 2017 Oct;8(5):759-767. doi: 10.1002/jcsm.12206. Epub 2017 May 10.


International Association for Hospice and Palliative Care Endorses Volitional Death by Starvation and Dehydration.

Baracos VE.

J Palliat Med. 2017 Jun;20(6):577. doi: 10.1089/jpm.2017.0044. Epub 2017 Mar 1. No abstract available.


Body Composition as a Prognostic Factor of Neoadjuvant Chemotherapy Toxicity and Outcome in Patients with Locally Advanced Gastric Cancer.

Palmela C, Velho S, Agostinho L, Branco F, Santos M, Santos MP, Oliveira MH, Strecht J, Maio R, Cravo M, Baracos VE.

J Gastric Cancer. 2017 Mar;17(1):74-87. doi: 10.5230/jgc.2017.17.e8. Epub 2017 Mar 14.


Mitogen-Activated Protein Kinases Inhibitors: Potential Therapeutic Agents for Cancer Cachexia.

Baracos VE.

Mol Cancer Ther. 2017 Feb;16(2):263-264. doi: 10.1158/1535-7163.MCT-16-0753. No abstract available.


Professor Kenneth Fearon: 3 August 1960-3 September 2016.

Ljungqvist O, Baracos VE.

Eur J Clin Nutr. 2017 Jan;71(1):1-2. doi: 10.1038/ejcn.2016.251. No abstract available.


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