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Transfer dynamics of Tn6648, a composite integrative conjugative element generated by tandem accretion of Tn5801 and Tn6647 in Enterococcus faecalis.

León-Sampedro R, Fernández-de-Bobadilla MD, San Millán Á, Baquero F, Coque TM.

J Antimicrob Chemother. 2019 Jun 21. pii: dkz239. doi: 10.1093/jac/dkz239. [Epub ahead of print]


Phylogenomics of Enterococcus faecalis from wild birds: new insights into host-associated differences in core and accessory genomes of the species.

León-Sampedro R, Del Campo R, Rodriguez-Baños M, Lanza VF, Pozuelo MJ, Francés-Cuesta C, Tedim AP, Freitas AR, Novais C, Peixe L, Willems RJL, Corander J, González Candelas F, Baquero F, Coque TM.

Environ Microbiol. 2019 Jun 4. doi: 10.1111/1462-2920.14702. [Epub ahead of print]


Antibiotic Killing of Diversely Generated Populations of Nonreplicating Bacteria.

McCall IC, Shah N, Govindan A, Baquero F, Levin BR.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e02360-18. doi: 10.1128/AAC.02360-18. Print 2019 Jul.


Simulating Multilevel Dynamics of Antimicrobial Resistance in a Membrane Computing Model.

Campos M, Capilla R, Naya F, Futami R, Coque T, Moya A, Fernandez-Lanza V, Cantón R, Sempere JM, Llorens C, Baquero F.

MBio. 2019 Jan 29;10(1). pii: e02460-18. doi: 10.1128/mBio.02460-18.


Biology of Hand-to-Hand Bacterial Transmission.

Del Campo R, Martínez-García L, Sánchez-Díaz AM, Baquero F.

Microbiol Spectr. 2019 Jan;7(1). doi: 10.1128/microbiolspec.MTBP-0011-2016.


Prediction of the intestinal resistome by a three-dimensional structure-based method.

Ruppé E, Ghozlane A, Tap J, Pons N, Alvarez AS, Maziers N, Cuesta T, Hernando-Amado S, Clares I, Martínez JL, Coque TM, Baquero F, Lanza VF, Máiz L, Goulenok T, de Lastours V, Amor N, Fantin B, Wieder I, Andremont A, van Schaik W, Rogers M, Zhang X, Willems RJL, de Brevern AG, Batto JM, Blottière HM, Léonard P, Léjard V, Letur A, Levenez F, Weiszer K, Haimet F, Doré J, Kennedy SP, Ehrlich SD.

Nat Microbiol. 2019 Jan;4(1):112-123. doi: 10.1038/s41564-018-0292-6. Epub 2018 Nov 26.


Causality in Biological Transmission: Forces and Energies.

Baquero F.

Microbiol Spectr. 2018 Sep;6(5). doi: 10.1128/microbiolspec.MTBP-0018-2016. Review.


Ceftazidime Is the Key Diversification and Selection Driver of VIM-Type Carbapenemases.

Martínez-García L, González-Alba JM, Baquero F, Cantón R, Galán JC.

MBio. 2018 May 8;9(3). pii: e02109-17. doi: 10.1128/mBio.02109-17.


Sciences unite in Spain to promote research for advancing society.

Baquero F, Gutiérrez-Fuentes JA.

Nature. 2018 Apr 5;556(7699):31. doi: 10.1038/d41586-018-04052-0. No abstract available.


In-depth resistome analysis by targeted metagenomics.

Lanza VF, Baquero F, Martínez JL, Ramos-Ruíz R, González-Zorn B, Andremont A, Sánchez-Valenzuela A, Ehrlich SD, Kennedy S, Ruppé E, van Schaik W, Willems RJ, de la Cruz F, Coque TM.

Microbiome. 2018 Jan 15;6(1):11. doi: 10.1186/s40168-017-0387-y.


Interventions on Metabolism: Making Antibiotic-Susceptible Bacteria.

Baquero F, Martínez JL.

MBio. 2017 Nov 28;8(6). pii: e01950-17. doi: 10.1128/mBio.01950-17.


Transmission as a basic process in microbial biology. Lwoff Award Prize Lecture.

Baquero F.

FEMS Microbiol Rev. 2017 Nov 1;41(6):816-827. doi: 10.1093/femsre/fux042. Review.


Individual Patterns of Complexity in Cystic Fibrosis Lung Microbiota, Including Predator Bacteria, over a 1-Year Period.

de Dios Caballero J, Vida R, Cobo M, Máiz L, Suárez L, Galeano J, Baquero F, Cantón R, Del Campo R.

MBio. 2017 Sep 26;8(5). pii: e00959-17. doi: 10.1128/mBio.00959-17.


Basic Sciences Fertilizing Clinical Microbiology and Infection Management.

Baquero F.

Clin Infect Dis. 2017 Aug 15;65(suppl_1):S80-S83. doi: 10.1093/cid/cix350.


Rewiring Microbiology and Infection.

Raoult D, Baquero F.

Clin Infect Dis. 2017 Aug 15;65(suppl_1):S1-S3. doi: 10.1093/cid/cix345. No abstract available.


Phagocytes, Antibiotics, and Self-Limiting Bacterial Infections.

Levin BR, Baquero F, Ankomah PP, McCall IC.

Trends Microbiol. 2017 Nov;25(11):878-892. doi: 10.1016/j.tim.2017.07.005. Epub 2017 Aug 24. Review.


Successful treatment of intrauterine cytomegalovirus infection with an intraventricular cyst in a dichorionic diamniotic twin gestation using cytomegalovirus immunoglobulin.

De la Calle M, Baquero F, Rodriguez R, González M, Fernández A, Omeñaca F, Bartha JL.

J Matern Fetal Neonatal Med. 2018 Aug;31(16):2226-2229. doi: 10.1080/14767058.2017.1338259. Epub 2017 Jul 6.


Complete Genome Sequences of Isolates of Enterococcus faecium Sequence Type 117, a Globally Disseminated Multidrug-Resistant Clone.

Tedim AP, Lanza VF, Manrique M, Pareja E, Ruiz-Garbajosa P, Cantón R, Baquero F, Coque TM, Tobes R.

Genome Announc. 2017 Mar 30;5(13). pii: e01553-16. doi: 10.1128/genomeA.01553-16.


Effect of the different 13-valent pneumococcal conjugate vaccination uptakes on the invasive pneumococcal disease in children: Analysis of a hospital-based and population-based surveillance study in Madrid, Spain, 2007-2015.

Picazo J, Ruiz-Contreras J, Casado-Flores J, Negreira S, Baquero F, Hernández-Sampelayo T, Otheo E, Méndez C; Heracles Study Group.

PLoS One. 2017 Feb 16;12(2):e0172222. doi: 10.1371/journal.pone.0172222. eCollection 2017.


Escherichia coli: an old friend with new tidings.

Vila J, Sáez-López E, Johnson JR, Römling U, Dobrindt U, Cantón R, Giske CG, Naas T, Carattoli A, Martínez-Medina M, Bosch J, Retamar P, Rodríguez-Baño J, Baquero F, Soto SM.

FEMS Microbiol Rev. 2016 Jul 1;40(4):437-463. doi: 10.1093/femsre/fuw005. Review.


A Numbers Game: Ribosome Densities, Bacterial Growth, and Antibiotic-Mediated Stasis and Death.

Levin BR, McCall IC, Perrot V, Weiss H, Ovesepian A, Baquero F.

MBio. 2017 Feb 7;8(1). pii: e02253-16. doi: 10.1128/mBio.02253-16.


Genomic and metagenomic technologies to explore the antibiotic resistance mobilome.

Martínez JL, Coque TM, Lanza VF, de la Cruz F, Baquero F.

Ann N Y Acad Sci. 2017 Jan;1388(1):26-41. doi: 10.1111/nyas.13282. Epub 2016 Nov 10. Review.


Co-diversification of Enterococcus faecium Core Genomes and PBP5: Evidences of pbp5 Horizontal Transfer.

Novais C, Tedim AP, Lanza VF, Freitas AR, Silveira E, Escada R, Roberts AP, Al-Haroni M, Baquero F, Peixe L, Coque TM.

Front Microbiol. 2016 Oct 6;7:1581. eCollection 2016.


AcCNET (Accessory Genome Constellation Network): comparative genomics software for accessory genome analysis using bipartite networks.

Lanza VF, Baquero F, de la Cruz F, Coque TM.

Bioinformatics. 2017 Jan 15;33(2):283-285. doi: 10.1093/bioinformatics/btw601. Epub 2016 Sep 23.


Long-term clonal dynamics of Enterococcus faecium strains causing bloodstream infections (1995-2015) in Spain.

Tedim AP, Ruíz-Garbajosa P, Rodríguez MC, Rodríguez-Baños M, Lanza VF, Derdoy L, Cárdenas Zurita G, Loza E, Cantón R, Baquero F, Coque TM.

J Antimicrob Chemother. 2017 Jan;72(1):48-55. Epub 2016 Sep 21.


Multilevel population genetic analysis of vanA and vanB Enterococcus faecium causing nosocomial outbreaks in 27 countries (1986-2012).

Freitas AR, Tedim AP, Francia MV, Jensen LB, Novais C, Peixe L, Sánchez-Valenzuela A, Sundsfjord A, Hegstad K, Werner G, Sadowy E, Hammerum AM, Garcia-Migura L, Willems RJ, Baquero F, Coque TM.

J Antimicrob Chemother. 2016 Dec;71(12):3351-3366. Epub 2016 Aug 15.


Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure.

Curiao T, Marchi E, Grandgirard D, León-Sampedro R, Viti C, Leib SL, Baquero F, Oggioni MR, Martinez JL, Coque TM.

BMC Genomics. 2016 Jul 13;17:491. doi: 10.1186/s12864-016-2778-z.


Global Emergence and Dissemination of Enterococci as Nosocomial Pathogens: Attack of the Clones?

Guzman Prieto AM, van Schaik W, Rogers MR, Coque TM, Baquero F, Corander J, Willems RJ.

Front Microbiol. 2016 May 26;7:788. doi: 10.3389/fmicb.2016.00788. eCollection 2016. Review.


Corrigendum to "The global threat of antimicrobial resistance: science for intervention" [New Microbes New Infect 6 (2015): 22-29].

Roca I, Akova M, Baquero F, Carlet J, Cavaleri M, Coenen S, Cohen J, Findlay D, Gyssens I, Heuer OE, Kahlmeter G, Kruse H, Laxminarayan R, Liébana E, López-Cerero L, MacGowan A, Martins M, Rodríguez-Baño J, Rolain JM, Segovia C, Sigauque B, Tacconelli E, Wellington E, Vila J.

New Microbes New Infect. 2015 Sep 10;8:175. doi: 10.1016/j.nmni.2015.09.004. eCollection 2015 Nov.


The refusal of the Society to accept antibiotic toxicity: missing opportunities for therapy of severe infections.

Rolain JM, Baquero F.

Clin Microbiol Infect. 2016 May;22(5):423-7. doi: 10.1016/j.cmi.2016.03.026. Epub 2016 Apr 2. Review.


The impact of host metapopulation structure on the population genetics of colonizing bacteria.

Numminen E, Gutmann M, Shubin M, Marttinen P, Méric G, van Schaik W, Coque TM, Baquero F, Willems RJ, Sheppard SK, Feil EJ, Hanage WP, Corander J.

J Theor Biol. 2016 May 7;396:53-62. doi: 10.1016/j.jtbi.2016.02.019. Epub 2016 Feb 23.


Diversity and Evolution of the Tn5801-tet(M)-Like Integrative and Conjugative Elements among Enterococcus, Streptococcus, and Staphylococcus.

León-Sampedro R, Novais C, Peixe L, Baquero F, Coque TM.

Antimicrob Agents Chemother. 2016 Jan 4;60(3):1736-46. doi: 10.1128/AAC.01864-15.


A membrane computing simulator of trans-hierarchical antibiotic resistance evolution dynamics in nested ecological compartments (ARES).

Campos M, Llorens C, Sempere JM, Futami R, Rodriguez I, Carrasco P, Capilla R, Latorre A, Coque TM, Moya A, Baquero F.

Biol Direct. 2015 Aug 5;10:41. doi: 10.1186/s13062-015-0070-9.


The Plasmidome of Firmicutes: Impact on the Emergence and the Spread of Resistance to Antimicrobials.

Lanza VF, Tedim AP, Martínez JL, Baquero F, Coque TM.

Microbiol Spectr. 2015 Apr;3(2):PLAS-0039-2014. doi: 10.1128/microbiolspec.PLAS-0039-2014. Review.


The global threat of antimicrobial resistance: science for intervention.

Roca I, Akova M, Baquero F, Carlet J, Cavaleri M, Coenen S, Cohen J, Findlay D, Gyssens I, Heuer OE, Kahlmeter G, Kruse H, Laxminarayan R, Liébana E, López-Cerero L, MacGowan A, Martins M, Rodríguez-Baño J, Rolain JM, Segovia C, Sigauque B, Tacconelli E, Wellington E, Vila J.

New Microbes New Infect. 2015 Apr 16;6:22-9. doi: 10.1016/j.nmni.2015.02.007. eCollection 2015 Jul. Review. Erratum in: New Microbes New Infect. 2015 Nov;8:175.


Prioritizing risks of antibiotic resistance genes in all metagenomes.

Martínez JL, Coque TM, Baquero F.

Nat Rev Microbiol. 2015 Jun;13(6):396. doi: 10.1038/nrmicro3399-c2. Epub 2015 Apr 27. No abstract available.


Public health evolutionary biology of antimicrobial resistance: priorities for intervention.

Baquero F, Lanza VF, Cantón R, Coque TM.

Evol Appl. 2015 Mar;8(3):223-39. doi: 10.1111/eva.12235. Epub 2014 Dec 11.


Polymorphic variation in susceptibility and metabolism of triclosan-resistant mutants of Escherichia coli and Klebsiella pneumoniae clinical strains obtained after exposure to biocides and antibiotics.

Curiao T, Marchi E, Viti C, Oggioni MR, Baquero F, Martinez JL, Coque TM.

Antimicrob Agents Chemother. 2015;59(6):3413-23. doi: 10.1128/AAC.00187-15. Epub 2015 Mar 30.


Tackling antibiotic resistance: the environmental framework.

Berendonk TU, Manaia CM, Merlin C, Fatta-Kassinos D, Cytryn E, Walsh F, Bürgmann H, Sørum H, Norström M, Pons MN, Kreuzinger N, Huovinen P, Stefani S, Schwartz T, Kisand V, Baquero F, Martinez JL.

Nat Rev Microbiol. 2015 May;13(5):310-7. doi: 10.1038/nrmicro3439. Epub 2015 Mar 30. Review.


Response to "In vivo attenuation and genetic evolution of a ST247-SCCmecI MRSA clone after 13 years of pathogenic bronchopulmonary colonization in a patient with cystic fibrosis: implications of the innate immune response".

López-Collazo E, Jurado T, de Dios Caballero J, Pérez-Vázquez M, Vindel A, Hernández-Jiménez E, Tamames J, Cubillos-Zapata C, Manrique M, Tobes R, Máiz L, Cantón R, Baquero F, del Campo R.

Mucosal Immunol. 2015 May;8(3):697-8. doi: 10.1038/mi.2015.10. Epub 2015 Mar 4. No abstract available.


Transcultural adaptation and validation of the CRAFFT as a screening test for problematic alcohol and substance use, abuse and dependence in a group of Argentine adolescents.

Bertini MC, Busaniche J, Baquero F, Eymann A, Krauss M, Paz M, Catsicaris C.

Arch Argent Pediatr. 2015 Apr;113(2):114-8. doi: 10.5546/aap.2015.114. English, Spanish.


Causes and interventions: need of a multiparametric analysis of microbial ecobiology.

Baquero F.

Environ Microbiol Rep. 2015 Feb;7(1):13-4. doi: 10.1111/1758-2229.12242. No abstract available.


Antibiotic-resistant Klebsiella pneumoniae and Escherichia coli high-risk clones and an IncFII(k) mosaic plasmid hosting Tn1 (blaTEM-4) in isolates from 1990 to 2004.

Rodríguez I, Novais Â, Lira F, Valverde A, Curião T, Martínez JL, Baquero F, Cantón R, Coque TM.

Antimicrob Agents Chemother. 2015 May;59(5):2904-8. doi: 10.1128/AAC.00296-15. Epub 2015 Feb 17.


Streptococcus gallolyticus subsp. gallolyticus from human and animal origins: genetic diversity, antimicrobial susceptibility, and characterization of a vancomycin-resistant calf isolate carrying a vanA-Tn1546-like element.

Romero-Hernández B, Tedim AP, Sánchez-Herrero JF, Librado P, Rozas J, Muñoz G, Baquero F, Cantón R, Del Campo R.

Antimicrob Agents Chemother. 2015 Apr;59(4):2006-15. doi: 10.1128/AAC.04083-14. Epub 2015 Jan 20.


Population biology of intestinal enterococcus isolates from hospitalized and nonhospitalized individuals in different age groups.

Tedim AP, Ruiz-Garbajosa P, Corander J, Rodríguez CM, Cantón R, Willems RJ, Baquero F, Coque TM.

Appl Environ Microbiol. 2015 Mar;81(5):1820-31. doi: 10.1128/AEM.03661-14. Epub 2014 Dec 29.


What is a resistance gene? Ranking risk in resistomes.

Martínez JL, Coque TM, Baquero F.

Nat Rev Microbiol. 2015 Feb;13(2):116-23. doi: 10.1038/nrmicro3399. Epub 2014 Dec 15. Review.


Widening the spaces of selection: evolution along sublethal antimicrobial gradients.

Baquero F, Coque TM.

MBio. 2014 Dec 9;5(6):e02270. doi: 10.1128/mBio.02270-14.


Molecular characterization and genetic diversity of ESBL-producing Escherichia coli colonizing the migratory Franklin's gulls (Leucophaeus pipixcan) in Antofagasta, North of Chile.

Báez J, Hernández-García M, Guamparito C, Díaz S, Olave A, Guerrero K, Cantón R, Baquero F, Gahona J, Valenzuela N, Del Campo R, Silva J.

Microb Drug Resist. 2015 Feb;21(1):111-6. doi: 10.1089/mdr.2014.0158. Epub 2014 Oct 14.


Proteomic analysis of the adaptation to warming in the Antarctic bacteria Shewanella frigidimarina.

García-Descalzo L, García-López E, Alcázar A, Baquero F, Cid C.

Biochim Biophys Acta. 2014 Dec;1844(12):2229-40. doi: 10.1016/j.bbapap.2014.08.006. Epub 2014 Aug 19.


Recombination blurs phylogenetic groups routine assignment in Escherichia coli: setting the record straight.

Turrientes MC, González-Alba JM, del Campo R, Baquero MR, Cantón R, Baquero F, Galán JC.

PLoS One. 2014 Aug 19;9(8):e105395. doi: 10.1371/journal.pone.0105395. eCollection 2014. Erratum in: PLoS One. 2014;9(11):e113532.

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