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Items: 39


Description and Characterization of a Novel Human Mast Cell Line for Scientific Study.

Kirshenbaum AS, Yin Y, Sundstrom JB, Bandara G, Metcalfe DD.

Int J Mol Sci. 2019 Nov 6;20(22). pii: E5520. doi: 10.3390/ijms20225520.


Oncogenic D816V-KIT signaling in mast cells causes persistent IL-6 production.

Tobío A, Bandara G, Morris DA, Kim DK, O'Connell MP, Komarow HD, Carter MC, Smrz D, Metcalfe DD, Olivera A.

Haematologica. 2020 Jan;105(1):124-135. doi: 10.3324/haematol.2018.212126. Epub 2019 Apr 4.


Mastocytosis-derived extracellular vesicles exhibit a mast cell signature, transfer KIT to stellate cells, and promote their activation.

Kim DK, Cho YE, Komarow HD, Bandara G, Song BJ, Olivera A, Metcalfe DD.

Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10692-E10701. doi: 10.1073/pnas.1809938115. Epub 2018 Oct 23.


Patients' ability to read and understand dosing instructions of their own medicines - a cross sectional study in a hospital and community pharmacy setting.

Manchanayake MGCA, Bandara GRWSK, Samaranayake NR.

BMC Health Serv Res. 2018 Jun 7;18(1):425. doi: 10.1186/s12913-018-3252-1.


Targeting Sphingosine Kinase Isoforms Effectively Reduces Growth and Survival of Neoplastic Mast Cells With D816V-KIT.

Bandara G, Muñoz-Cano R, Tobío A, Yin Y, Komarow HD, Desai A, Metcalfe DD, Olivera A.

Front Immunol. 2018 Mar 28;9:631. doi: 10.3389/fimmu.2018.00631. eCollection 2018.


Chromatographic Separation and Visual Detection on Wicking Microfluidic Devices: Quantitation of Cu2+ in Surface, Ground, and Drinking Water.

Bandara GC, Heist CA, Remcho VT.

Anal Chem. 2018 Feb 20;90(4):2594-2600. doi: 10.1021/acs.analchem.7b04087. Epub 2018 Jan 26.


Patterned polycaprolactone-filled glass microfiber microfluidic devices for total protein content analysis.

Bandara GC, Heist CA, Remcho VT.

Talanta. 2018 Jan 1;176:589-594. doi: 10.1016/j.talanta.2017.08.031. Epub 2017 Aug 16.


Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis.

Kim DK, Beaven MA, Kulinski JM, Desai A, Bandara G, Bai Y, Prussin C, Schwartz LB, Komarow H, Metcalfe DD, Olivera A.

PLoS One. 2016 Sep 9;11(9):e0162831. doi: 10.1371/journal.pone.0162831. eCollection 2016.


Immunophenotypic and Ultrastructural Analysis of Mast Cells in Hermansky-Pudlak Syndrome Type-1: A Possible Connection to Pulmonary Fibrosis.

Kirshenbaum AS, Cruse G, Desai A, Bandara G, Leerkes M, Lee CC, Fischer ER, O'Brien KJ, Gochuico BR, Stone K, Gahl WA, Metcalfe DD.

PLoS One. 2016 Jul 26;11(7):e0159177. doi: 10.1371/journal.pone.0159177. eCollection 2016.


Activated mast cells synthesize and release soluble ST2-a decoy receptor for IL-33.

Bandara G, Beaven MA, Olivera A, Gilfillan AM, Metcalfe DD.

Eur J Immunol. 2015 Nov;45(11):3034-44. doi: 10.1002/eji.201545501. Epub 2015 Sep 9.


Detection of water contamination from hydraulic fracturing wastewater: a μPAD for bromide analysis in natural waters.

Loh LJ, Bandara GC, Weber GL, Remcho VT.

Analyst. 2015 Aug 21;140(16):5501-7. doi: 10.1039/c5an00807g.


Estrogen increases the severity of anaphylaxis in female mice through enhanced endothelial nitric oxide synthase expression and nitric oxide production.

Hox V, Desai A, Bandara G, Gilfillan AM, Metcalfe DD, Olivera A.

J Allergy Clin Immunol. 2015 Mar;135(3):729-36.e5. doi: 10.1016/j.jaci.2014.11.003. Epub 2014 Dec 29.


Growth of human mast cells from bone marrow and peripheral blood-derived CD34(+) pluripotent hematopoietic cells.

Bandara G, Metcalfe DD, Kirshenbaum AS.

Methods Mol Biol. 2015;1220:155-62. doi: 10.1007/978-1-4939-1568-2_10.


Mastocytosis associated with a rare germline KIT K509I mutation displays a well-differentiated mast cell phenotype.

Chan EC, Bai Y, Kirshenbaum AS, Fischer ER, Simakova O, Bandara G, Scott LM, Wisch LB, Cantave D, Carter MC, Lewis JC, Noel P, Maric I, Gilfillan AM, Metcalfe DD, Wilson TM.

J Allergy Clin Immunol. 2014 Jul;134(1):178-87. doi: 10.1016/j.jaci.2013.12.1090. Epub 2014 Feb 28.


Genotype-dependent effects of TGF-β1 on mast cell function: targeting the Stat5 pathway.

Fernando J, Faber TW, Pullen NA, Falanga YT, Kolawole EM, Oskeritzian CA, Barnstein BO, Bandara G, Li G, Schwartz LB, Spiegel S, Straus DB, Conrad DH, Bunting KD, Ryan JJ.

J Immunol. 2013 Nov 1;191(9):4505-13. doi: 10.4049/jimmunol.1202723. Epub 2013 Sep 25.


KIT GNNK splice variants: expression in systemic mastocytosis and influence on the activating potential of the D816V mutation in mast cells.

Chan EC, Bai Y, Bandara G, Simakova O, Brittain E, Scott L, Dyer KD, Klion AD, Maric I, Gilfillan AM, Metcalfe DD, Wilson TM.

Exp Hematol. 2013 Oct;41(10):870-881.e2. doi: 10.1016/j.exphem.2013.05.005. Epub 2013 Jun 4.


Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells.

Smrž D, Bandara G, Beaven MA, Metcalfe DD, Gilfillan AM.

Eur J Immunol. 2013 Jul;43(7):1873-82. doi: 10.1002/eji.201243214. Epub 2013 Jun 4.


A novel KIT-deficient mouse mast cell model for the examination of human KIT-mediated activation responses.

Smrž D, Bandara G, Zhang S, Mock BA, Beaven MA, Metcalfe DD, Gilfillan AM.

J Immunol Methods. 2013 Apr 30;390(1-2):52-62. doi: 10.1016/j.jim.2013.01.008. Epub 2013 Jan 25.


IL-33 induces a hyporesponsive phenotype in human and mouse mast cells.

Jung MY, Smrž D, Desai A, Bandara G, Ito T, Iwaki S, Kang JH, Andrade MV, Hilderbrand SC, Brown JM, Beaven MA, Metcalfe DD, Gilfillan AM.

J Immunol. 2013 Jan 15;190(2):531-8. doi: 10.4049/jimmunol.1201576. Epub 2012 Dec 17.


Targeting the KIT activating switch control pocket: a novel mechanism to inhibit neoplastic mast cell proliferation and mast cell activation.

Bai Y, Bandara G, Ching Chan E, Maric I, Simakova O, Bandara SN, Lu WP, Wise SC, Flynn DL, Metcalfe DD, Gilfillan AM, Wilson TM.

Leukemia. 2013 Feb;27(2):278-85. doi: 10.1038/leu.2012.218. Epub 2012 Jul 31. Review.


Stem cell factor programs the mast cell activation phenotype.

Ito T, Smrž D, Jung MY, Bandara G, Desai A, Smržová Š, Kuehn HS, Beaven MA, Metcalfe DD, Gilfillan AM.

J Immunol. 2012 Jun 1;188(11):5428-37. doi: 10.4049/jimmunol.1103366. Epub 2012 Apr 23.


Examination of the role of TRPM8 in human mast cell activation and its relevance to the etiology of cold-induced urticaria.

Medic N, Desai A, Komarow H, Burch LH, Bandara G, Beaven MA, Metcalfe DD, Gilfillan AM.

Cell Calcium. 2011 Nov;50(5):473-80. doi: 10.1016/j.ceca.2011.08.003. Epub 2011 Sep 8.


CD72 negatively regulates KIT-mediated responses in human mast cells.

Kataoka TR, Kumanogoh A, Bandara G, Metcalfe DD, Gilfillan AM.

J Immunol. 2010 Mar 1;184(5):2468-75. doi: 10.4049/jimmunol.0902450. Epub 2010 Jan 25.


Preparation of human metabolites of propranolol using laboratory-evolved bacterial cytochromes P450.

Otey CR, Bandara G, Lalonde J, Takahashi K, Arnold FH.

Biotechnol Bioeng. 2006 Feb 20;93(3):494-9.


Functional evolution and structural conservation in chimeric cytochromes p450: calibrating a structure-guided approach.

Otey CR, Silberg JJ, Voigt CA, Endelman JB, Bandara G, Arnold FH.

Chem Biol. 2004 Mar;11(3):309-18.


Saturation mutagenesis.

Georgescu R, Bandara G, Sun L.

Methods Mol Biol. 2003;231:75-83. No abstract available.


Expression and stabilization of galactose oxidase in Escherichia coli by directed evolution.

Sun L, Petrounia IP, Yagasaki M, Bandara G, Arnold FH.

Protein Eng. 2001 Sep;14(9):699-704.


Functional expression of horseradish peroxidase in Saccharomyces cerevisiae and Pichia pastoris.

Morawski B, Lin Z, Cirino P, Joo H, Bandara G, Arnold FH.

Protein Eng. 2000 May;13(5):377-84.


Functional contributions of the FcepsilonRIalpha and FepsilonRIgamma subunit domains in FcepsilonRI-mediated signaling in mast cells.

Repetto B, Bandara G, Kado-Fong H, Larigan JD, Wiggan GA, Pocius D, Basu M, Gilfillan AM, Kochan JP.

J Immunol. 1996 Jun 15;156(12):4876-83.


Direct gene delivery to synovium. An evaluation of potential vectors in vitro and in vivo.

Nita I, Ghivizzani SC, Galea-Lauri J, Bandara G, Georgescu HI, Robbins PD, Evans CH.

Arthritis Rheum. 1996 May;39(5):820-8.


Functional characterization of the signal transduction events mediated by Fc epsilon RI alpha and gamma chimeric receptors.

Repetto B, Bandara G, Wiggan GA, Gilfillan AM, Kochan JP.

Int Arch Allergy Immunol. 1995 May-Jun;107(1-3):66-8.


Intraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transfer.

Bandara G, Mueller GM, Galea-Lauri J, Tindal MH, Georgescu HI, Suchanek MK, Hung GL, Glorioso JC, Robbins PD, Evans CH.

Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10764-8.


Synovial cell transplants for gene transfer to joints.

Evans CH, Bandara G, Mueller G, Robbins P, Glorioso JC, Georgescu HI.

Transplant Proc. 1992 Dec;24(6):2966. No abstract available.


The synovial activation of chondrocytes: evidence for complex cytokine interactions involving a possible novel factor.

Bandara G, Lin CW, Georgescu HI, Evans CH.

Biochim Biophys Acta. 1992 Apr 7;1134(3):309-18.


Gene transfer to synoviocytes: prospects for gene treatment of arthritis.

Bandara G, Robbins PD, Georgescu HI, Mueller GM, Glorioso JC, Evans CH.

DNA Cell Biol. 1992 Apr;11(3):227-31. Review.


Synovial activation of chondrocytes: evidence for complex cytokine interactions.

Bandara G, Georgescu HI, Lin CW, Evans CH.

Agents Actions. 1991 Sep;34(1-2):285-8.


Chondrocyte activation by interleukin-1: analysis of the synergistic properties of fibroblast growth factor and phorbol myristate acetate.

Bandara G, Lin CW, Georgescu HI, Mendelow D, Evans CH.

Arch Biochem Biophys. 1989 Nov 1;274(2):539-47.


Chondrocyte activation by interleukin-1: synergism with fibroblast growth factor and phorbol myristate acetate.

Bandara G, Lin CW, Georgescu HI, Mendelow D, Evans CH.

Agents Actions. 1989 Jun;27(3-4):439-41.


Induction of collagenase mRNA in lapine articular chondrocytes by synovial factors and interleukin-1.

Lin CW, Phillips SL, Brinckerhoff CE, Georgescu HI, Bandara G, Evans CH.

Arch Biochem Biophys. 1988 Jul;264(1):351-4.


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