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Items: 15

1.

Synthesis of amide and sulfonamide substituted N-aryl 6-aminoquinoxalines as PFKFB3 inhibitors with improved physicochemical properties.

Boutard N, Białas A, Sabiniarz A, Guzik P, Banaszak K, Biela A, Bień M, Buda A, Bugaj B, Cieluch E, Cierpich A, Dudek Ł, Eggenweiler HM, Fogt J, Gaik M, Gondela A, Jakubiec K, Jurzak M, Kitlińska A, Kowalczyk P, Kujawa M, Kwiecińska K, Leś M, Lindemann R, Maciuszek M, Mikulski M, Niedziejko P, Obara A, Pawlik H, Rzymski T, Sieprawska-Lupa M, Sowińska M, Szeremeta-Spisak J, Stachowicz A, Tomczyk MM, Wiklik K, Włoszczak Ł, Ziemiańska S, Zarębski A, Brzózka K, Nowak M, Fabritius CH.

Bioorg Med Chem Lett. 2019 Feb 15;29(4):646-653. doi: 10.1016/j.bmcl.2018.12.034. Epub 2018 Dec 16.

PMID:
30626557
2.

Discovery and Structure-Activity Relationships of N-Aryl 6-Aminoquinoxalines as Potent PFKFB3 Kinase Inhibitors.

Boutard N, Białas A, Sabiniarz A, Guzik P, Banaszak K, Biela A, Bień M, Buda A, Bugaj B, Cieluch E, Cierpich A, Dudek Ł, Eggenweiler HM, Fogt J, Gaik M, Gondela A, Jakubiec K, Jurzak M, Kitlińska A, Kowalczyk P, Kujawa M, Kwiecińska K, Leś M, Lindemann R, Maciuszek M, Mikulski M, Niedziejko P, Obara A, Pawlik H, Rzymski T, Sieprawska-Lupa M, Sowińska M, Szeremeta-Spisak J, Stachowicz A, Tomczyk MM, Wiklik K, Włoszczak Ł, Ziemiańska S, Zarębski A, Brzózka K, Nowak M, Fabritius CH.

ChemMedChem. 2019 Jan 8;14(1):169-181. doi: 10.1002/cmdc.201800569. Epub 2018 Dec 6.

PMID:
30378281
3.

QTL mapping for benzoxazinoid content, preharvest sprouting, α-amylase activity, and leaf rust resistance in rye (Secale cereale L.).

Milczarski P, Masojć P, Krajewski P, Stochmal A, Kowalczyk M, Angelov M, Ivanova V, Schollenberger M, Wakuliński W, Banaszak Z, Banaszak K, Rakoczy-Trojanowska M.

PLoS One. 2017 Dec 21;12(12):e0189912. doi: 10.1371/journal.pone.0189912. eCollection 2017.

4.

Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.

Jarmuła A, Wilk P, Maj P, Ludwiczak J, Dowierciał A, Banaszak K, Rypniewski W, Cieśla J, Dąbrowska M, Frączyk T, Bronowska AK, Jakowiecki J, Filipek S, Rode W.

J Mol Graph Model. 2017 Oct;77:33-50. doi: 10.1016/j.jmgm.2017.08.008. Epub 2017 Aug 12.

PMID:
28826032
5.

Identification of Single Nucleotide Polymorphisms Associated with Brown Rust Resistance, α-Amylase Activity and Pre-harvest Sprouting in Rye (Secale cereale L.).

Rakoczy-Trojanowska M, Krajewski P, Bocianowski J, Schollenberger M, Wakuliński W, Milczarski P, Masojć P, Targońska-Karasek M, Banaszak Z, Banaszak K, Brukwiński W, Orczyk W, Kilian A.

Plant Mol Biol Report. 2017;35(3):366-378. doi: 10.1007/s11105-017-1030-6. Epub 2017 Apr 26.

6.

The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches--toward anti-sense therapy against TREDs.

Kiliszek A, Banaszak K, Dauter Z, Rypniewski W.

Nucleic Acids Res. 2016 Feb 29;44(4):1937-43. doi: 10.1093/nar/gkv1513. Epub 2015 Dec 29.

7.

Watson-Crick-like pairs in CCUG repeats: evidence for tautomeric shifts or protonation.

Rypniewski W, Banaszak K, Kuliński T, Kiliszek A.

RNA. 2016 Jan;22(1):22-31. doi: 10.1261/rna.052399.115. Epub 2015 Nov 5.

8.

Mitochondria-targeted spin traps: synthesis, superoxide spin trapping, and mitochondrial uptake.

Hardy M, Poulhés F, Rizzato E, Rockenbauer A, Banaszak K, Karoui H, Lopez M, Zielonka J, Vasquez-Vivar J, Sethumadhavan S, Kalyanaraman B, Tordo P, Ouari O.

Chem Res Toxicol. 2014 Jul 21;27(7):1155-65. doi: 10.1021/tx500032e. Epub 2014 Jun 13.

9.

Crystal structure of phosphoramide-phosphorylated thymidylate synthase reveals pSer127, reflecting probably pHis to pSer phosphotransfer.

Wilk P, Jarmuła A, Ruman T, Banaszak K, Rypniewski W, Cieśla J, Dowierciał A, Rode W.

Bioorg Chem. 2014 Feb;52:44-9. doi: 10.1016/j.bioorg.2013.11.003. Epub 2013 Nov 21.

PMID:
24321279
10.

Selectivity of Ni(II) and Zn(II) binding to Sporosarcina pasteurii UreE, a metallochaperone in the urease assembly: a calorimetric and crystallographic study.

Zambelli B, Banaszak K, Merloni A, Kiliszek A, Rypniewski W, Ciurli S.

J Biol Inorg Chem. 2013 Dec;18(8):1005-17. doi: 10.1007/s00775-013-1049-6. Epub 2013 Oct 15.

PMID:
24126709
11.

Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni²⁺ and Zn²⁺ reveals a role for the disordered C-terminal arm in metal trafficking.

Banaszak K, Martin-Diaconescu V, Bellucci M, Zambelli B, Rypniewski W, Maroney MJ, Ciurli S.

Biochem J. 2012 Feb 1;441(3):1017-26. doi: 10.1042/BJ20111659.

12.

The crystal structures of eukaryotic phosphofructokinases from baker's yeast and rabbit skeletal muscle.

Banaszak K, Mechin I, Obmolova G, Oldham M, Chang SH, Ruiz T, Radermacher M, Kopperschläger G, Rypniewski W.

J Mol Biol. 2011 Mar 25;407(2):284-97. doi: 10.1016/j.jmb.2011.01.019. Epub 2011 Jan 15.

PMID:
21241708
13.

Probing cucurbituril assemblies in water with TEMPO-like nitroxides: a trinitroxide supraradical with spin-spin interactions.

Bardelang D, Banaszak K, Karoui H, Rockenbauer A, Waite M, Udachin K, Ripmeester JA, Ratcliffe CI, Ouari O, Tordo P.

J Am Chem Soc. 2009 Apr 22;131(15):5402-4. doi: 10.1021/ja900306m.

PMID:
19334727
14.

Inclusion complexes of EMPO derivatives with 2,6-di-O-methyl-beta-cyclodextrin: synthesis, NMR and EPR investigations for enhanced superoxide detection.

Bardelang D, Rockenbauer A, Karoui H, Finet JP, Biskupska I, Banaszak K, Tordo P.

Org Biomol Chem. 2006 Aug 7;4(15):2874-82. Epub 2006 Jun 30.

PMID:
16855735
15.

Structure of the reduced disulfide-bond isomerase DsbC from Escherichia coli.

Banaszak K, Mechin I, Frost G, Rypniewski W.

Acta Crystallogr D Biol Crystallogr. 2004 Oct;60(Pt 10):1747-52. Epub 2004 Sep 23.

PMID:
15388920

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