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Items: 17

1.

oHSV therapy increases trametinib access to brain tumors and sensitizes them in vivo.

Yoo JY, Swanner J, Otani Y, Nair M, Park F, Banasavadi-Siddegowda Y, Liu J, Jaime-Ramirez AC, Hong B, Geng F, Guo D, Bystry D, Pelphs M, Quadri H, Lee TJ, Kaur B.

Neuro Oncol. 2019 May 7. pii: noz079. doi: 10.1093/neuonc/noz079. [Epub ahead of print]

PMID:
31063549
2.

Enhancing Therapeutic Efficacy of Oncolytic Herpes Simplex Virus-1 with Integrin ╬▓1 Blocking Antibody OS2966.

Lee TJ, Nair M, Banasavadi-Siddegowda Y, Liu J, Nallanagulagari T, Jaime-Ramirez AC, Guo JY, Quadri H, Zhang J, Bockhorst KH, Aghi MK, Carbonell WS, Kaur B, Yoo JY.

Mol Cancer Ther. 2019 Jun;18(6):1127-1136. doi: 10.1158/1535-7163.MCT-18-0953. Epub 2019 Mar 29.

PMID:
30926634
3.

Suppression of HMGB1 Released in the Glioblastoma Tumor Microenvironment Reduces Tumoral Edema.

Hong B, Muili K, Bolyard C, Russell L, Lee TJ, Banasavadi-Siddegowda Y, Yoo JY, Yan Y, Ballester LY, Bockhorst KH, Kaur B.

Mol Ther Oncolytics. 2018 Dec 6;12:93-102. doi: 10.1016/j.omto.2018.11.005. eCollection 2019 Mar 29.

4.

PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance.

Russell L, Swanner J, Jaime-Ramirez AC, Wang Y, Sprague A, Banasavadi-Siddegowda Y, Yoo JY, Sizemore GM, Kladney R, Zhang J, Lehman NL, Ostrowski MC, Hong B, Caligiuri M, Yu J, Kaur B.

Nat Commun. 2018 Nov 27;9(1):5006. doi: 10.1038/s41467-018-07344-1.

5.

PRMT5 as a druggable target for glioblastoma therapy.

Banasavadi-Siddegowda YK, Welker AM, An M, Yang X, Zhou W, Shi G, Imitola J, Li C, Hsu S, Wang J, Phelps M, Zhang J, Beattie CE, Baiocchi R, Kaur B.

Neuro Oncol. 2018 May 18;20(6):753-763. doi: 10.1093/neuonc/nox206.

6.

A novel interaction of PAK4 with PPAR╬│ to regulate Nox1 and radiation-induced epithelial-to-mesenchymal transition in glioma.

Kesanakurti D, Maddirela D, Banasavadi-Siddegowda YK, Lai TH, Qamri Z, Jacob NK, Sampath D, Mohanam S, Kaur B, Puduvalli VK.

Oncogene. 2017 Sep 14;36(37):5309-5320. doi: 10.1038/onc.2016.261. Epub 2017 May 22.

7.

Sex as a biological variable in response to temozolomide.

Russell L, Bolyard C, Banasavadi-Siddegowda Y, Weiss A, Zhang J, Shakya R, Powell K, Kaur B.

Neuro Oncol. 2017 Jun 1;19(6):873-874. doi: 10.1093/neuonc/nox040. No abstract available.

8.

Humanized chondroitinase ABC sensitizes glioblastoma cells to temozolomide.

Jaime-Ramirez AC, Dmitrieva N, Yoo JY, Banasavadi-Siddegowda Y, Zhang J, Relation T, Bolyard C, Wojton J, Kaur B.

J Gene Med. 2017 Mar;19(3). doi: 10.1002/jgm.2942.

9.

BAI1 Orchestrates Macrophage Inflammatory Response to HSV Infection-Implications for Oncolytic Viral Therapy.

Bolyard C, Meisen WH, Banasavadi-Siddegowda Y, Hardcastle J, Yoo JY, Wohleb ES, Wojton J, Yu JG, Dubin S, Khosla M, Xu B, Smith J, Alvarez-Breckenridge C, Pow-Anpongkul P, Pichiorri F, Zhang J, Old M, Zhu D, Van Meir EG, Godbout JP, Caligiuri MA, Yu J, Kaur B.

Clin Cancer Res. 2017 Apr 1;23(7):1809-1819. doi: 10.1158/1078-0432.CCR-16-1818. Epub 2016 Nov 9.

10.

PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells.

Banasavadi-Siddegowda YK, Russell L, Frair E, Karkhanis VA, Relation T, Yoo JY, Zhang J, Sif S, Imitola J, Baiocchi R, Kaur B.

Oncogene. 2017 Jan 12;36(2):263-274. doi: 10.1038/onc.2016.199. Epub 2016 Jun 13.

11.

Nanofiber-based paramagnetic probes for rapid, real-time biomedical oximetry.

Bhallamudi VP, Xue R, Purser CM, Presley KF, Banasavadi-Siddegowda YK, Hwang J, Kaur B, Hammel PC, Poirier MG, Lannutti JJ, Pandian RP.

Biomed Microdevices. 2016 Apr;18(2):38. doi: 10.1007/s10544-016-0063-1.

PMID:
27106026
12.

Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma.

Yan F, Alinari L, Lustberg ME, Martin LK, Cordero-Nieves HM, Banasavadi-Siddegowda Y, Virk S, Barnholtz-Sloan J, Bell EH, Wojton J, Jacob NK, Chakravarti A, Nowicki MO, Wu X, Lapalombella R, Datta J, Yu B, Gordon K, Haseley A, Patton JT, Smith PL, Ryu J, Zhang X, Mo X, Marcucci G, Nuovo G, Kwon CH, Byrd JC, Chiocca EA, Li C, Sif S, Jacob S, Lawler S, Kaur B, Baiocchi RA.

Cancer Res. 2014 Mar 15;74(6):1752-65. doi: 10.1158/0008-5472.CAN-13-0884. Epub 2014 Jan 22.

13.

MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells.

Joshi K, Banasavadi-Siddegowda Y, Mo X, Kim SH, Mao P, Kig C, Nardini D, Sobol RW, Chow LM, Kornblum HI, Waclaw R, Beullens M, Nakano I.

Stem Cells. 2013 Jun;31(6):1051-63. doi: 10.1002/stem.1358.

14.

Tumor-specific activation of the C-JUN/MELK pathway regulates glioma stem cell growth in a p53-dependent manner.

Gu C, Banasavadi-Siddegowda YK, Joshi K, Nakamura Y, Kurt H, Gupta S, Nakano I.

Stem Cells. 2013 May;31(5):870-81. doi: 10.1002/stem.1322.

15.

Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complex.

Guvenc H, Pavlyukov MS, Joshi K, Kurt H, Banasavadi-Siddegowda YK, Mao P, Hong C, Yamada R, Kwon CH, Bhasin D, Chettiar S, Kitange G, Park IH, Sarkaria JN, Li C, Shakhparonov MI, Nakano I.

Clin Cancer Res. 2013 Feb 1;19(3):631-42. doi: 10.1158/1078-0432.CCR-12-0647. Epub 2012 Dec 18.

16.

Human heat shock protein 105/110 kDa (Hsp105/110) regulates biogenesis and quality control of misfolded cystic fibrosis transmembrane conductance regulator at multiple levels.

Saxena A, Banasavadi-Siddegowda YK, Fan Y, Bhattacharya S, Roy G, Giovannucci DR, Frizzell RA, Wang X.

J Biol Chem. 2012 Jun 1;287(23):19158-70. doi: 10.1074/jbc.M111.297580. Epub 2012 Apr 13.

17.

FKBP38 peptidylprolyl isomerase promotes the folding of cystic fibrosis transmembrane conductance regulator in the endoplasmic reticulum.

Banasavadi-Siddegowda YK, Mai J, Fan Y, Bhattacharya S, Giovannucci DR, Sanchez ER, Fischer G, Wang X.

J Biol Chem. 2011 Dec 16;286(50):43071-80. doi: 10.1074/jbc.M111.269993. Epub 2011 Oct 26.

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