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Items: 1 to 50 of 110

1.

Introduction to Special Issue on "Frontiers in Industrial Microbiology and Biotechnology 2019".

Baltz RH, Gonzalez R.

J Ind Microbiol Biotechnol. 2019 Oct;46(9-10):1237. doi: 10.1007/s10295-019-02230-1. No abstract available.

PMID:
31473862
2.

Introduction to the special issue: "Natural Product Discovery and Development in the Genomic Era: 2019".

Baltz RH, Abe I, Kim ES, Müller R, Van Lanen SG, Wright G.

J Ind Microbiol Biotechnol. 2019 Mar;46(3-4):249. doi: 10.1007/s10295-019-02138-w. No abstract available.

PMID:
30729341
3.

Natural product drug discovery in the genomic era: realities, conjectures, misconceptions, and opportunities.

Baltz RH.

J Ind Microbiol Biotechnol. 2019 Mar;46(3-4):281-299. doi: 10.1007/s10295-018-2115-4. Epub 2018 Nov 27.

PMID:
30484124
4.

Bacteriophage-resistant industrial fermentation strains: from the cradle to CRISPR/Cas9.

Baltz RH.

J Ind Microbiol Biotechnol. 2018 Nov;45(11):1003-1006. doi: 10.1007/s10295-018-2079-4. Epub 2018 Sep 6. Review.

PMID:
30191429
5.

Synthetic biology advances and applications in the biotechnology industry: a perspective.

Katz L, Chen YY, Gonzalez R, Peterson TC, Zhao H, Baltz RH.

J Ind Microbiol Biotechnol. 2018 Jul;45(7):449-461. doi: 10.1007/s10295-018-2056-y. Epub 2018 Jun 18.

PMID:
29915997
6.

Correction to: Synthetic biology, genome mining, and combinatorial biosynthesis of NRPS‑derived antibiotics: a perspective.

Baltz RH.

J Ind Microbiol Biotechnol. 2018 Jul;45(7):651-655. doi: 10.1007/s10295-018-2022-8.

PMID:
29479639
7.

Synthetic biology, genome mining, and combinatorial biosynthesis of NRPS-derived antibiotics: a perspective.

Baltz RH.

J Ind Microbiol Biotechnol. 2018 Jul;45(7):635-649. doi: 10.1007/s10295-017-1999-8. Epub 2017 Dec 29. Erratum in: J Ind Microbiol Biotechnol. 2018 Feb 26;:.

PMID:
29288438
8.

Introduction to the Special Issue: "Arnold Demain-Industrial Microbiologist Extraordinaire".

Baltz RH, Vandamme E, Zhang L, Gonzalez R.

J Ind Microbiol Biotechnol. 2017 May;44(4-5):503. doi: 10.1007/s10295-017-1922-3. No abstract available.

PMID:
28451909
9.

Molecular beacons to identify gifted microbes for genome mining.

Baltz RH.

J Antibiot (Tokyo). 2017 May;70(5):639-646. doi: 10.1038/ja.2017.1. Epub 2017 Jan 25.

PMID:
28119518
10.

Gifted microbes for genome mining and natural product discovery.

Baltz RH.

J Ind Microbiol Biotechnol. 2017 May;44(4-5):573-588. doi: 10.1007/s10295-016-1815-x. Epub 2016 Aug 12. Review.

PMID:
27520548
11.

Natural product discovery: past, present, and future.

Katz L, Baltz RH.

J Ind Microbiol Biotechnol. 2016 Mar;43(2-3):155-76. doi: 10.1007/s10295-015-1723-5. Epub 2016 Jan 6. Review.

PMID:
26739136
12.

Introduction to the Special Issue: "Natural Product Discovery and Development in the Genomic Era".

Baltz RH, Ikeda H, Katz L, Kim ES, van Wezel GP, Wright G.

J Ind Microbiol Biotechnol. 2016 Mar;43(2-3):109. doi: 10.1007/s10295-015-1715-5. No abstract available.

PMID:
26660315
13.

Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes.

Baltz RH.

J Ind Microbiol Biotechnol. 2016 Mar;43(2-3):343-70. doi: 10.1007/s10295-015-1682-x. Epub 2015 Sep 12. Review.

PMID:
26364200
14.
15.

Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?

Bachmann BO, Van Lanen SG, Baltz RH.

J Ind Microbiol Biotechnol. 2014 Feb;41(2):175-84. doi: 10.1007/s10295-013-1389-9. Epub 2013 Dec 17. Review.

16.

MbtH homology codes to identify gifted microbes for genome mining.

Baltz RH.

J Ind Microbiol Biotechnol. 2014 Feb;41(2):357-69. doi: 10.1007/s10295-013-1360-9. Epub 2013 Nov 7.

PMID:
24197465
17.
18.

Streptomyces temperate bacteriophage integration systems for stable genetic engineering of actinomycetes (and other organisms).

Baltz RH.

J Ind Microbiol Biotechnol. 2012 May;39(5):661-72. doi: 10.1007/s10295-011-1069-6. Epub 2011 Dec 13. Review.

PMID:
22160317
19.

Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery.

Baltz RH.

J Ind Microbiol Biotechnol. 2011 Nov;38(11):1747-60. doi: 10.1007/s10295-011-1022-8. Epub 2011 Aug 9. Review.

PMID:
21826462
20.

Strain improvement in actinomycetes in the postgenomic era.

Baltz RH.

J Ind Microbiol Biotechnol. 2011 Jun;38(6):657-66. doi: 10.1007/s10295-010-0934-z. Epub 2011 Jan 21. Review.

PMID:
21253811
21.

Production of novel lipopeptide antibiotics related to A54145 by Streptomyces fradiae mutants blocked in biosynthesis of modified amino acids and assignment of lptJ, lptK and lptL gene functions.

Alexander DC, Rock J, Gu JQ, Mascio C, Chu M, Brian P, Baltz RH.

J Antibiot (Tokyo). 2011 Jan;64(1):79-87. doi: 10.1038/ja.2010.138. Epub 2010 Nov 24.

PMID:
21102596
22.

Structural characterization of a lipopeptide antibiotic A54145E(Asn3Asp9) produced by a genetically engineered strain of Streptomyces fradiae.

Gu JQ, Alexander DC, Rock J, Brian P, Chu M, Baltz RH.

J Antibiot (Tokyo). 2011 Jan;64(1):111-6. doi: 10.1038/ja.2010.140. Epub 2010 Nov 24.

PMID:
21102593
23.

Development of a genetic system for combinatorial biosynthesis of lipopeptides in Streptomyces fradiae and heterologous expression of the A54145 biosynthesis gene cluster.

Alexander DC, Rock J, He X, Brian P, Miao V, Baltz RH.

Appl Environ Microbiol. 2010 Oct;76(20):6877-87. doi: 10.1128/AEM.01248-10. Epub 2010 Aug 27.

24.

Genomics and the ancient origins of the daptomycin biosynthetic gene cluster.

Baltz RH.

J Antibiot (Tokyo). 2010 Aug;63(8):506-11. doi: 10.1038/ja.2010.82. Epub 2010 Jul 21.

PMID:
20648020
25.

Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters.

Baltz RH.

J Ind Microbiol Biotechnol. 2010 Aug;37(8):759-72. doi: 10.1007/s10295-010-0730-9. Epub 2010 May 14. Review.

PMID:
20467781
26.

Genetically engineered lipopeptide antibiotics related to A54145 and daptomycin with improved properties.

Nguyen KT, He X, Alexander DC, Li C, Gu JQ, Mascio C, Van Praagh A, Mortin L, Chu M, Silverman JA, Brian P, Baltz RH.

Antimicrob Agents Chemother. 2010 Apr;54(4):1404-13. doi: 10.1128/AAC.01307-09. Epub 2010 Jan 19.

27.

Daptomycin: from the mountain to the clinic, with essential help from Francis Tally, MD.

Eisenstein BI, Oleson FB Jr, Baltz RH.

Clin Infect Dis. 2010 Jan 1;50 Suppl 1:S10-5. doi: 10.1086/647938. Review.

PMID:
20067387
28.

Chapter 20. Biosynthesis and genetic engineering of lipopeptides in Streptomyces roseosporus.

Baltz RH.

Methods Enzymol. 2009;458:511-31. doi: 10.1016/S0076-6879(09)04820-4.

PMID:
19374996
29.

Daptomycin: mechanisms of action and resistance, and biosynthetic engineering.

Baltz RH.

Curr Opin Chem Biol. 2009 Apr;13(2):144-51. doi: 10.1016/j.cbpa.2009.02.031. Epub 2009 Mar 19. Review.

PMID:
19303806
30.

Non-ribosomal peptide synthetase module fusions to produce derivatives of daptomycin in Streptomyces roseosporus.

Doekel S, Coëffet-Le Gal MF, Gu JQ, Chu M, Baltz RH, Brian P.

Microbiology. 2008 Sep;154(Pt 9):2872-80. doi: 10.1099/mic.0.2008/020685-0.

PMID:
18757821
31.

Renaissance in antibacterial discovery from actinomycetes.

Baltz RH.

Curr Opin Pharmacol. 2008 Oct;8(5):557-63. doi: 10.1016/j.coph.2008.04.008. Epub 2008 Jun 3. Review.

PMID:
18524678
32.

Biosynthesis and genetic engineering of lipopeptide antibiotics related to daptomycin.

Baltz RH.

Curr Top Med Chem. 2008;8(8):618-38. Review.

PMID:
18473888
33.

Structural characterization of daptomycin analogues A21978C1-3(d-Asn11) produced by a recombinant Streptomyces roseosporus strain.

Gu JQ, Nguyen KT, Gandhi C, Rajgarhia V, Baltz RH, Brian P, Chu M.

J Nat Prod. 2007 Feb;70(2):233-40. Epub 2007 Feb 7.

PMID:
17284073
34.

Molecular engineering approaches to peptide, polyketide and other antibiotics.

Baltz RH.

Nat Biotechnol. 2006 Dec;24(12):1533-40. Review.

PMID:
17160059
35.

Combinatorial biosynthesis of novel antibiotics related to daptomycin.

Nguyen KT, Ritz D, Gu JQ, Alexander D, Chu M, Miao V, Brian P, Baltz RH.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17462-7. Epub 2006 Nov 7.

36.

Complementation of daptomycin dptA and dptD deletion mutations in trans and production of hybrid lipopeptide antibiotics.

Coëffet-Le Gal MF, Thurston L, Rich P, Miao V, Baltz RH.

Microbiology. 2006 Oct;152(Pt 10):2993-3001.

PMID:
17005980
37.

A glutamic acid 3-methyltransferase encoded by an accessory gene locus important for daptomycin biosynthesis in Streptomyces roseosporus.

Nguyen KT, Kau D, Gu JQ, Brian P, Wrigley SK, Baltz RH, Miao V.

Mol Microbiol. 2006 Sep;61(5):1294-307.

38.

Genetic engineering in Streptomyces roseosporus to produce hybrid lipopeptide antibiotics.

Miao V, Coëffet-Le Gal MF, Nguyen K, Brian P, Penn J, Whiting A, Steele J, Kau D, Martin S, Ford R, Gibson T, Bouchard M, Wrigley SK, Baltz RH.

Chem Biol. 2006 Mar;13(3):269-76.

39.

Marcel Faber Roundtable: is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration?

Baltz RH.

J Ind Microbiol Biotechnol. 2006 Jul;33(7):507-13. Epub 2006 Jan 18. Review.

PMID:
16418869
40.

Natural products to drugs: daptomycin and related lipopeptide antibiotics.

Baltz RH, Miao V, Wrigley SK.

Nat Prod Rep. 2005 Dec;22(6):717-41. Epub 2005 Nov 4. Review.

PMID:
16311632
41.

Heterologous production of daptomycin in Streptomyces lividans.

Penn J, Li X, Whiting A, Latif M, Gibson T, Silva CJ, Brian P, Davies J, Miao V, Wrigley SK, Baltz RH.

J Ind Microbiol Biotechnol. 2006 Feb;33(2):121-8. Epub 2005 Nov 1.

PMID:
16261359
42.

Dedication to professor Julian Davies.

Baltz RH.

J Ind Microbiol Biotechnol. 2006 Feb;33(2):64-5. Epub 2005 Oct 7. No abstract available.

PMID:
16211372
43.

The lipopeptide antibiotic A54145 biosynthetic gene cluster from Streptomyces fradiae.

Miao V, Brost R, Chapple J, She K, Gal MF, Baltz RH.

J Ind Microbiol Biotechnol. 2006 Feb;33(2):129-40. Epub 2005 Oct 6.

PMID:
16208464
44.

Combinatorial biosynthesis of lipopeptide antibiotics in Streptomyces roseosporus.

Baltz RH, Brian P, Miao V, Wrigley SK.

J Ind Microbiol Biotechnol. 2006 Feb;33(2):66-74. Epub 2005 Sep 28.

PMID:
16193281
45.

Spectinomycin resistance in rpsE mutants is recessive in Streptomyces roseosporus.

He X, Miao V, Baltz RH.

J Antibiot (Tokyo). 2005 Apr;58(4):284-8.

PMID:
15981417
46.

Daptomycin biosynthesis in Streptomyces roseosporus: cloning and analysis of the gene cluster and revision of peptide stereochemistry.

Miao V, Coëffet-Legal MF, Brian P, Brost R, Penn J, Whiting A, Martin S, Ford R, Parr I, Bouchard M, Silva CJ, Wrigley SK, Baltz RH.

Microbiology. 2005 May;151(Pt 5):1507-23.

PMID:
15870461
47.

Combinatorial glycosylation of glycopeptide antibiotics.

Baltz RH.

Chem Biol. 2002 Dec;9(12):1268-70. Review.

48.

Genetic methods and strategies for secondary metabolite yield improvement in actinomycetes.

Baltz RH.

Antonie Van Leeuwenhoek. 2001 Sep;79(3-4):251-9. Review.

PMID:
11816967
49.

Genes for the biosynthesis of spinosyns: applications for yield improvement in Saccharopolyspora spinosa.

Madduri K, Waldron C, Matsushima P, Broughton MC, Crawford K, Merlo DJ, Baltz RH.

J Ind Microbiol Biotechnol. 2001 Dec;27(6):399-402. Review.

PMID:
11774006
50.

Genome of the bacterium Streptococcus pneumoniae strain R6.

Hoskins J, Alborn WE Jr, Arnold J, Blaszczak LC, Burgett S, DeHoff BS, Estrem ST, Fritz L, Fu DJ, Fuller W, Geringer C, Gilmour R, Glass JS, Khoja H, Kraft AR, Lagace RE, LeBlanc DJ, Lee LN, Lefkowitz EJ, Lu J, Matsushima P, McAhren SM, McHenney M, McLeaster K, Mundy CW, Nicas TI, Norris FH, O'Gara M, Peery RB, Robertson GT, Rockey P, Sun PM, Winkler ME, Yang Y, Young-Bellido M, Zhao G, Zook CA, Baltz RH, Jaskunas SR, Rosteck PR Jr, Skatrud PL, Glass JI.

J Bacteriol. 2001 Oct;183(19):5709-17.

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