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Items: 1 to 50 of 318


Association of Nutritional Support With Clinical Outcomes Among Medical Inpatients Who Are Malnourished or at Nutritional Risk: An Updated Systematic Review and Meta-analysis.

Gomes F, Baumgartner A, Bounoure L, Bally M, Deutz NE, Greenwald JL, Stanga Z, Mueller B, Schuetz P.

JAMA Netw Open. 2019 Nov 1;2(11):e1915138. doi: 10.1001/jamanetworkopen.2019.15138.


Gel Phase 1,2-Distearoyl-sn-glycero-3-phosphocholine-Based Liposomes Are Superior to Fluid Phase Liposomes at Augmenting Both Antigen Presentation on Major Histocompatibility Complex Class II and Costimulatory Molecule Display by Dendritic Cells in Vitro.

Norling K, Bernasconi V, Agmo Hernández V, Parveen N, Edwards K, Lycke NY, Höök F, Bally M.

ACS Infect Dis. 2019 Nov 8;5(11):1867-1878. doi: 10.1021/acsinfecdis.9b00189. Epub 2019 Sep 24.


Characterization of a liposomal copper(II)-quercetin formulation suitable for parenteral use.

Chen KTJ, Anantha M, Leung AWY, Kulkarni JA, Militao GGC, Wehbe M, Sutherland B, Cullis PR, Bally MB.

Drug Deliv Transl Res. 2020 Feb;10(1):202-215. doi: 10.1007/s13346-019-00674-7.


Recent Treatment Advances and the Role of Nanotechnology, Combination Products, and Immunotherapy in Changing the Therapeutic Landscape of Acute Myeloid Leukemia.

Chen KTJ, Gilabert-Oriol R, Bally MB, Leung AWY.

Pharm Res. 2019 Jun 24;36(9):125. doi: 10.1007/s11095-019-2654-z. Review.


Liposomal OTS964, a TOPK inhibitor: a simple method to estimate OTS964 association with liposomes that relies on enhanced OTS964 fluorescence when bound to albumin.

Gilabert-Oriol R, Sutherland BW, Anantha M, Pallaoro A, Bally MB.

Drug Deliv Transl Res. 2019 Dec;9(6):1082-1094. doi: 10.1007/s13346-019-00651-0.


Bacteria-Based Production of Thiol-Clickable, Genetically Encoded Lipid Nanovesicles.

Royes J, Ilioaia O, Lubart Q, Angius F, Dubacheva GV, Bally M, Miroux B, Tribet C.

Angew Chem Int Ed Engl. 2019 May 27;58(22):7395-7399. doi: 10.1002/anie.201902929. Epub 2019 Apr 23.


What Drives Innovation: The Canadian Touch on Liposomal Therapeutics.

Leung AWY, Amador C, Wang LC, Mody UV, Bally MB.

Pharmaceutics. 2019 Mar 16;11(3). pii: E124. doi: 10.3390/pharmaceutics11030124. Review.


Nanoplasmonic Sensor Detects Preferential Binding of IRSp53 to Negative Membrane Curvature.

Emilsson G, Röder E, Malekian B, Xiong K, Manzi J, Tsai FC, Cho NJ, Bally M, Dahlin A.

Front Chem. 2019 Feb 4;7:1. doi: 10.3389/fchem.2019.00001. eCollection 2019.


Regulatory Mechanisms of the Mucin-Like Region on Herpes Simplex Virus during Cellular Attachment.

Delguste M, Peerboom N, Le Brun G, Trybala E, Olofsson S, Bergström T, Alsteens D, Bally M.

ACS Chem Biol. 2019 Mar 15;14(3):534-542. doi: 10.1021/acschembio.9b00064. Epub 2019 Feb 21.


Liposomal formulations of carboplatin injected by convection-enhanced delivery increases the median survival time of F98 glioma bearing rats.

Shi M, Anantha M, Wehbe M, Bally MB, Fortin D, Roy LO, Charest G, Richer M, Paquette B, Sanche L.

J Nanobiotechnology. 2018 Oct 5;16(1):77. doi: 10.1186/s12951-018-0404-8.


Liposomal Formulations to Modulate the Tumour Microenvironment and Antitumour Immune Response.

Gilabert-Oriol R, Ryan GM, Leung AWY, Firmino NS, Bennewith KL, Bally MB.

Int J Mol Sci. 2018 Sep 26;19(10). pii: E2922. doi: 10.3390/ijms19102922. Review.


Histone Deacetylase Inhibitors Synergize with Catalytic Inhibitors of EZH2 to Exhibit Antitumor Activity in Small Cell Carcinoma of the Ovary, Hypercalcemic Type.

Wang Y, Chen SY, Colborne S, Lambert G, Shin CY, Santos ND, Orlando KA, Lang JD, Hendricks WPD, Bally MB, Karnezis AN, Hass R, Underhill TM, Morin GB, Trent JM, Weissman BE, Huntsman DG.

Mol Cancer Ther. 2018 Dec;17(12):2767-2779. doi: 10.1158/1535-7163.MCT-18-0348. Epub 2018 Sep 19.


Studying additive interaction in a healthcare database: Case study of NSAIDs, cardiovascular profiles, and acute myocardial infarction.

Bally M, Nadeau L, Brophy JM.

PLoS One. 2018 Aug 10;13(8):e0201884. doi: 10.1371/journal.pone.0201884. eCollection 2018.


A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B.

Bosc D, Vezenkov L, Bortnik S, An J, Xu J, Choutka C, Hannigan AM, Kovacic S, Loo S, Clark PGK, Chen G, Guay-Ross RN, Yang K, Dragowska WH, Zhang F, Go NE, Leung A, Honson NS, Pfeifer TA, Gleave M, Bally M, Jones SJ, Gorski SM, Young RN.

Sci Rep. 2018 Aug 3;8(1):11653. doi: 10.1038/s41598-018-29900-x.


Copper-CX-5461: A novel liposomal formulation for a small molecule rRNA synthesis inhibitor.

Leung AWY, Anantha M, Dragowska WH, Wehbe M, Bally MB.

J Control Release. 2018 Sep 28;286:1-9. doi: 10.1016/j.jconrel.2018.07.025. Epub 2018 Jul 18.


Effective Refractive Index and Lipid Content of Extracellular Vesicles Revealed Using Optical Waveguide Scattering and Fluorescence Microscopy.

Rupert DLM, Mapar M, Shelke GV, Norling K, Elmeskog M, Lötvall JO, Block S, Bally M, Agnarsson B, Höök F.

Langmuir. 2018 Jul 24;34(29):8522-8531. doi: 10.1021/acs.langmuir.7b04214. Epub 2018 Jul 11.


Cell Membrane Derived Platform To Study Virus Binding Kinetics and Diffusion with Single Particle Sensitivity.

Peerboom N, Schmidt E, Trybala E, Block S, Bergström T, Pace HP, Bally M.

ACS Infect Dis. 2018 Jun 8;4(6):944-953. doi: 10.1021/acsinfecdis.7b00270. Epub 2018 May 8.


Authors' reply to commentary: Renewed controversy over cardiovascular risk with non-steroidal anti-inflammatory drugs.

Brophy JM, Bally M.

Int J Epidemiol. 2018 Apr 1;47(2):674-675. doi: 10.1093/ije/dyy050. No abstract available.


Transition Metal Ions Promote the Bioavailability of Hydrophobic Therapeutics: Cu and Zn Interactions with RNA Polymerase I Inhibitor CX5461.

Prosser KE, Leung AWY, Harrypersad S, Lewis AR, Bally MB, Walsby CJ.

Chemistry. 2018 Apr 25;24(24):6334-6338. doi: 10.1002/chem.201800289. Epub 2018 Apr 6.


Copeptin levels and commonly used laboratory parameters in hospitalised patients with severe hypernatraemia - the "Co-MED study".

Nigro N, Winzeler B, Suter-Widmer I, Schuetz P, Arici B, Bally M, Refardt J, Betz M, Gashi G, Urwyler SA, Burget L, Blum CA, Bock A, Huber A, Müller B, Christ-Crain M.

Crit Care. 2018 Feb 9;22(1):33. doi: 10.1186/s13054-018-1955-7.


Development of a copper-clioquinol formulation suitable for intravenous use.

Wehbe M, Malhotra AK, Anantha M, Lo C, Dragowska WH, Dos Santos N, Bally MB.

Drug Deliv Transl Res. 2018 Feb;8(1):239-251. doi: 10.1007/s13346-017-0455-7.


Risk of acute myocardial infarction with real-world NSAIDs depends on dose and timing of exposure.

Bally M, Beauchamp ME, Abrahamowicz M, Nadeau L, Brophy JM.

Pharmacoepidemiol Drug Saf. 2018 Jan;27(1):69-77. doi: 10.1002/pds.4358. Epub 2017 Nov 24.


In Vivo Validation of PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1) as a Cisplatin-sensitizing Therapeutic Target.

Leung AWY, Veinotte CJ, Melong N, Oh MH, Chen K, Enfield KSS, Backstrom I, Warburton C, Yapp D, Berman JN, Bally MB, Lockwood WW.

Clin Cancer Res. 2017 Nov 1;23(21):6555-6566. doi: 10.1158/1078-0432.CCR-17-0700. Epub 2017 Aug 8.


Copper (II) complexes of bidentate ligands exhibit potent anti-cancer activity regardless of platinum sensitivity status.

Wehbe M, Lo C, Leung AWY, Dragowska WH, Ryan GM, Bally MB.

Invest New Drugs. 2017 Dec;35(6):682-690. doi: 10.1007/s10637-017-0488-2. Epub 2017 Jul 21.


Authors' reply to Wicks.

Bally M, Brophy JM.

BMJ. 2017 Jul 19;358:j3434. doi: 10.1136/bmj.j3434. No abstract available.


A Perspective - can copper complexes be developed as a novel class of therapeutics?

Wehbe M, Leung AWY, Abrams MJ, Orvig C, Bally MB.

Dalton Trans. 2017 Aug 22;46(33):10758-10773. doi: 10.1039/c7dt01955f. Review.


Regional and local environmental conditions do not shape the response to warming of a marine habitat-forming species.

Crisci C, Ledoux JB, Mokhtar-Jamaï K, Bally M, Bensoussan N, Aurelle D, Cebrian E, Coma R, Féral JP, La Rivière M, Linares C, López-Sendino P, Marschal C, Ribes M, Teixidó N, Zuberer F, Garrabou J.

Sci Rep. 2017 Jul 11;7(1):5069. doi: 10.1038/s41598-017-05220-4.


Binding Kinetics and Lateral Mobility of HSV-1 on End-Grafted Sulfated Glycosaminoglycans.

Peerboom N, Block S, Altgärde N, Wahlsten O, Möller S, Schnabelrauch M, Trybala E, Bergström T, Bally M.

Biophys J. 2017 Sep 19;113(6):1223-1234. doi: 10.1016/j.bpj.2017.06.028. Epub 2017 Jul 8.


Authors' reply to Evans.

Bally M, Brophy JM.

BMJ. 2017 Jul 3;358:j3185. doi: 10.1136/bmj.j3185. No abstract available.


Development and optimization of an injectable formulation of copper diethyldithiocarbamate, an active anticancer agent.

Wehbe M, Anantha M, Shi M, Leung AW, Dragowska WH, Sanche L, Bally MB.

Int J Nanomedicine. 2017 May 31;12:4129-4146. doi: 10.2147/IJN.S137347. eCollection 2017.


Liposomes and lipid bilayers in biosensors.

Mazur F, Bally M, Städler B, Chandrawati R.

Adv Colloid Interface Sci. 2017 Nov;249:88-99. doi: 10.1016/j.cis.2017.05.020. Epub 2017 May 31. Review.


Characteristics and outcomes of patients with profound hyponatraemia due to primary polydipsia.

Sailer CO, Winzeler B, Nigro N, Suter-Widmer I, Arici B, Bally M, Schuetz P, Mueller B, Christ-Crain M.

Clin Endocrinol (Oxf). 2017 Nov;87(5):492-499. doi: 10.1111/cen.13384. Epub 2017 Jul 7.


Optimization of liposomal topotecan for use in treating neuroblastoma.

Chernov L, Deyell RJ, Anantha M, Dos Santos N, Gilabert-Oriol R, Bally MB.

Cancer Med. 2017 Jun;6(6):1240-1254. doi: 10.1002/cam4.1083. Epub 2017 May 23.


Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data.

Bally M, Dendukuri N, Rich B, Nadeau L, Helin-Salmivaara A, Garbe E, Brophy JM.

BMJ. 2017 May 9;357:j1909. doi: 10.1136/bmj.j1909. Review.


Unique therapeutic properties and preparation methodology of multivalent rituximab-lipid nanoparticles.

Popov J, Gilabert-Oriol R, Bally MB.

Eur J Pharm Biopharm. 2017 Aug;117:256-269. doi: 10.1016/j.ejpb.2017.04.024. Epub 2017 Apr 24.


The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.

Wang Y, Chen SY, Karnezis AN, Colborne S, Santos ND, Lang JD, Hendricks WP, Orlando KA, Yap D, Kommoss F, Bally MB, Morin GB, Trent JM, Weissman BE, Huntsman DG.

J Pathol. 2017 Jul;242(3):371-383. doi: 10.1002/path.4912. Epub 2017 Jun 2.


In vitro assay for measuring real time topotecan release from liposomes: release kinetics and cellular internalization.

Gilabert-Oriol R, Chernov L, Anantha M, Dragowska WH, Bally MB.

Drug Deliv Transl Res. 2017 Aug;7(4):544-557. doi: 10.1007/s13346-017-0380-9.


Histo-Blood Group Antigen Presentation Is Critical for Binding of Norovirus VLP to Glycosphingolipids in Model Membranes.

Nasir W, Frank M, Kunze A, Bally M, Parra F, Nyholm PG, Höök F, Larson G.

ACS Chem Biol. 2017 May 19;12(5):1288-1296. doi: 10.1021/acschembio.7b00152. Epub 2017 Mar 27.


Gentamicin B1 is a minor gentamicin component with major nonsense mutation suppression activity.

Baradaran-Heravi A, Niesser J, Balgi AD, Choi K, Zimmerman C, South AP, Anderson HJ, Strynadka NC, Bally MB, Roberge M.

Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3479-3484. doi: 10.1073/pnas.1620982114. Epub 2017 Mar 13. Retraction in: Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11885.


A simple passive equilibration method for loading carboplatin into pre-formed liposomes incubated with ethanol as a temperature dependent permeability enhancer.

Wehbe M, Malhotra A, Anantha M, Roosendaal J, Leung AWY, Plackett D, Edwards K, Gilabert-Oriol R, Bally MB.

J Control Release. 2017 Apr 28;252:50-61. doi: 10.1016/j.jconrel.2017.03.010. Epub 2017 Mar 10.


The cyanobacterial metabolite nocuolin a is a natural oxadiazine that triggers apoptosis in human cancer cells.

Voráčová K, Hájek J, Mareš J, Urajová P, Kuzma M, Cheel J, Villunger A, Kapuscik A, Bally M, Novák P, Kabeláč M, Krumschnabel G, Lukeš M, Voloshko L, Kopecký J, Hrouzek P.

PLoS One. 2017 Mar 2;12(3):e0172850. doi: 10.1371/journal.pone.0172850. eCollection 2017.


CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.

Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O'Neil NJ, Santos ND, Silvester J, Wei V, Garcia J, Kabeer F, Lai D, Soriano P, Banáth J, Chiu DS, Yap D, Le DD, Ye FB, Zhang A, Thu K, Soong J, Lin SC, Tsai AH, Osako T, Algara T, Saunders DN, Wong J, Xian J, Bally MB, Brenton JD, Brown GW, Shah SP, Cescon D, Mak TW, Caldas C, Stirling PC, Hieter P, Balasubramanian S, Aparicio S.

Nat Commun. 2017 Feb 17;8:14432. doi: 10.1038/ncomms14432.


A nano flow cytometer for single lipid vesicle analysis.

Friedrich R, Block S, Alizadehheidari M, Heider S, Fritzsche J, Esbjörner EK, Westerlund F, Bally M.

Lab Chip. 2017 Feb 28;17(5):830-841. doi: 10.1039/c6lc01302c.


Mucosal Vaccine Development Based on Liposome Technology.

Bernasconi V, Norling K, Bally M, Höök F, Lycke NY.

J Immunol Res. 2016;2016:5482087. doi: 10.1155/2016/5482087. Epub 2016 Dec 29. Review.


The Matrix protein M1 from influenza C virus induces tubular membrane invaginations in an in vitro cell membrane model.

Saletti D, Radzimanowski J, Effantin G, Midtvedt D, Mangenot S, Weissenhorn W, Bassereau P, Bally M.

Sci Rep. 2017 Jan 25;7:40801. doi: 10.1038/srep40801.


Metformin prevents metabolic side effects during systemic glucocorticoid treatment.

Seelig E, Meyer S, Timper K, Nigro N, Bally M, Pernicova I, Schuetz P, Müller B, Korbonits M, Christ-Crain M.

Eur J Endocrinol. 2017 Mar;176(3):349-358. doi: 10.1530/EJE-16-0653. Epub 2017 Jan 10.


Industry sponsorship and outcomes of nutrition studies: Is there an association when looking at the trial level?

Schuetz P, Meier MA, Bally MR, Gomes F, Mueller B.

Clin Nutr. 2017 Apr;36(2):616-618. doi: 10.1016/j.clnu.2016.12.017. Epub 2016 Dec 26. No abstract available.


Mastoparan is a membranolytic anti-cancer peptide that works synergistically with gemcitabine in a mouse model of mammary carcinoma.

Hilchie AL, Sharon AJ, Haney EF, Hoskin DW, Bally MB, Franco OL, Corcoran JA, Hancock REW.

Biochim Biophys Acta. 2016 Dec;1858(12):3195-3204. doi: 10.1016/j.bbamem.2016.09.021. Epub 2016 Oct 18.


Synthetic lethality in lung cancer and translation to clinical therapies.

Leung AW, de Silva T, Bally MB, Lockwood WW.

Mol Cancer. 2016 Sep 29;15(1):61. Review.


Evaluation of copeptin and commonly used laboratory parameters for the differential diagnosis of profound hyponatraemia in hospitalized patients: 'The Co-MED Study'.

Nigro N, Winzeler B, Suter-Widmer I, Schuetz P, Arici B, Bally M, Blum CA, Nickel CH, Bingisser R, Bock A, Huber A, Müller B, Christ-Crain M.

Clin Endocrinol (Oxf). 2017 Mar;86(3):456-462. doi: 10.1111/cen.13243. Epub 2016 Oct 7.


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