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Items: 8


Hereditary ovarian cancer and two-compartment tumor metabolism: epithelial loss of BRCA1 induces hydrogen peroxide production, driving oxidative stress and NFκB activation in the tumor stroma.

Martinez-Outschoorn UE, Balliet RM, Lin Z, Whitaker-Menezes D, Howell A, Sotgia F, Lisanti MP.

Cell Cycle. 2012 Nov 15;11(22):4152-66. doi: 10.4161/cc.22226. Epub 2012 Oct 9.


Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection.

Balliet RM, Capparelli C, Guido C, Pestell TG, Martinez-Outschoorn UE, Lin Z, Whitaker-Menezes D, Chiavarina B, Pestell RG, Howell A, Sotgia F, Lisanti MP.

Cell Cycle. 2011 Dec 1;10(23):4065-73. doi: 10.4161/cc.10.23.18254. Epub 2011 Dec 1.


Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts.

Trimmer C, Sotgia F, Whitaker-Menezes D, Balliet RM, Eaton G, Martinez-Outschoorn UE, Pavlides S, Howell A, Iozzo RV, Pestell RG, Scherer PE, Capozza F, Lisanti MP.

Cancer Biol Ther. 2011 Feb 15;11(4):383-94. Epub 2011 Feb 15.


Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells.

Martinez-Outschoorn UE, Balliet RM, Rivadeneira DB, Chiavarina B, Pavlides S, Wang C, Whitaker-Menezes D, Daumer KM, Lin Z, Witkiewicz AK, Flomenberg N, Howell A, Pestell RG, Knudsen ES, Sotgia F, Lisanti MP.

Cell Cycle. 2010 Aug 15;9(16):3256-76. doi: 10.4161/cc.9.16.12553. Epub 2010 Aug 28.


Sex differences in UDP-glucuronosyltransferase 2B17 expression and activity.

Gallagher CJ, Balliet RM, Sun D, Chen G, Lazarus P.

Drug Metab Dispos. 2010 Dec;38(12):2204-9. doi: 10.1124/dmd.110.035345. Epub 2010 Sep 1.


Characterization of UGTs active against SAHA and association between SAHA glucuronidation activity phenotype with UGT genotype.

Balliet RM, Chen G, Gallagher CJ, Dellinger RW, Sun D, Lazarus P.

Cancer Res. 2009 Apr 1;69(7):2981-9. doi: 10.1158/0008-5472.CAN-08-4143. Epub 2009 Mar 24.


Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases.

Sun D, Sharma AK, Dellinger RW, Blevins-Primeau AS, Balliet RM, Chen G, Boyiri T, Amin S, Lazarus P.

Drug Metab Dispos. 2007 Nov;35(11):2006-14. Epub 2007 Jul 30.


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