Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 114

1.

Epigenetic interplay between immune, stromal and cancer cells in the tumor microenvironment.

Garcia-Gomez A, Rodríguez-Ubreva J, Ballestar E.

Clin Immunol. 2018 Mar 6. pii: S1521-6616(18)30131-1. doi: 10.1016/j.clim.2018.02.013. [Epub ahead of print]

PMID:
29501540
2.

Prostaglandin E2 Leads to the Acquisition of DNMT3A-Dependent Tolerogenic Functions in Human Myeloid-Derived Suppressor Cells.

Rodríguez-Ubreva J, Català-Moll F, Obermajer N, Álvarez-Errico D, Ramirez RN, Company C, Vento-Tormo R, Moreno-Bueno G, Edwards RP, Mortazavi A, Kalinski P, Ballestar E.

Cell Rep. 2017 Oct 3;21(1):154-167. doi: 10.1016/j.celrep.2017.09.018.

3.

TET2- and TDG-mediated changes are required for the acquisition of distinct histone modifications in divergent terminal differentiation of myeloid cells.

Garcia-Gomez A, Li T, Kerick M, Català-Moll F, Comet NR, Rodríguez-Ubreva J, de la Rica L, Branco MR, Martín J, Ballestar E.

Nucleic Acids Res. 2017 Sep 29;45(17):10002-10017. doi: 10.1093/nar/gkx666.

4.

New insights into the epigenetics of inflammatory rheumatic diseases.

Ballestar E, Li T.

Nat Rev Rheumatol. 2017 Oct;13(10):593-605. doi: 10.1038/nrrheum.2017.147. Epub 2017 Sep 14. Review.

PMID:
28905855
5.

Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites.

Rodríguez-Cortez VC, Martínez-Redondo P, Català-Moll F, Rodríguez-Ubreva J, Garcia-Gomez A, Poorani-Subramani G, Ciudad L, Hernando H, Pérez-García A, Company C, Urquiza JM, Ramiro AR, Di Noia JM, Vaquero A, Ballestar E.

Sci Rep. 2017 Aug 8;7(1):7594. doi: 10.1038/s41598-017-07380-9.

6.

Epigenetic mechanisms of myeloid differentiation in the tumor microenvironment.

Rodríguez-Ubreva J, Garcia-Gomez A, Ballestar E.

Curr Opin Pharmacol. 2017 Aug;35:20-29. doi: 10.1016/j.coph.2017.04.008. Epub 2017 May 25. Review.

PMID:
28551408
7.

Genetic and Epigenetic Determinants in Autoinflammatory Diseases.

Álvarez-Errico D, Vento-Tormo R, Ballestar E.

Front Immunol. 2017 Mar 22;8:318. doi: 10.3389/fimmu.2017.00318. eCollection 2017. Review.

8.

In vivo conditional deletion of HDAC7 reveals its requirement to establish proper B lymphocyte identity and development.

Azagra A, Román-González L, Collazo O, Rodríguez-Ubreva J, de Yébenes VG, Barneda-Zahonero B, Rodríguez J, Castro de Moura M, Grego-Bessa J, Fernández-Duran I, Islam AB, Esteller M, Ramiro AR, Ballestar E, Parra M.

J Exp Med. 2016 Nov 14;213(12):2591-2601. Epub 2016 Oct 17.

9.

Epigenetics: DNA methylation signatures in Sjögren syndrome.

Renaudineau Y, Ballestar E.

Nat Rev Rheumatol. 2016 Oct;12(10):565-6. doi: 10.1038/nrrheum.2016.144. Epub 2016 Sep 9. No abstract available.

PMID:
27627868
10.

DNA demethylation of inflammasome-associated genes is enhanced in patients with cryopyrin-associated periodic syndromes.

Vento-Tormo R, Álvarez-Errico D, Garcia-Gomez A, Hernández-Rodríguez J, Buján S, Basagaña M, Méndez M, Yagüe J, Juan M, Aróstegui JI, Ballestar E.

J Allergy Clin Immunol. 2017 Jan;139(1):202-211.e6. doi: 10.1016/j.jaci.2016.05.016. Epub 2016 Jul 7.

PMID:
27394913
11.

The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis.

Gómez-Del Arco P, Perdiguero E, Yunes-Leites PS, Acín-Pérez R, Zeini M, Garcia-Gomez A, Sreenivasan K, Jiménez-Alcázar M, Segalés J, López-Maderuelo D, Ornés B, Jiménez-Borreguero LJ, D'Amato G, Enshell-Seijffers D, Morgan B, Georgopoulos K, Islam AB, Braun T, de la Pompa JL, Kim J, Enriquez JA, Ballestar E, Muñoz-Cánoves P, Redondo JM.

Cell Metab. 2016 May 10;23(5):881-92. doi: 10.1016/j.cmet.2016.04.008.

12.

Dissecting Epigenetic Dysregulation of Primary Antibody Deficiencies.

Rodríguez-Cortez VC, Del Pino-Molina L, Rodríguez-Ubreva J, López-Granados E, Ballestar E.

J Clin Immunol. 2016 May;36 Suppl 1:48-56. doi: 10.1007/s10875-016-0267-4. Epub 2016 Mar 17. Review.

PMID:
26984849
13.

Chromatin-wide and transcriptome profiling integration uncovers p38α MAPK as a global regulator of skeletal muscle differentiation.

Segalés J, Islam AB, Kumar R, Liu QC, Sousa-Victor P, Dilworth FJ, Ballestar E, Perdiguero E, Muñoz-Cánoves P.

Skelet Muscle. 2016 Mar 15;6:9. doi: 10.1186/s13395-016-0074-x. eCollection 2016.

14.

IL-4 orchestrates STAT6-mediated DNA demethylation leading to dendritic cell differentiation.

Vento-Tormo R, Company C, Rodríguez-Ubreva J, de la Rica L, Urquiza JM, Javierre BM, Sabarinathan R, Luque A, Esteller M, Aran JM, Álvarez-Errico D, Ballestar E.

Genome Biol. 2016 Jan 13;17:4. doi: 10.1186/s13059-015-0863-2.

15.

Autophagy maintains stemness by preventing senescence.

García-Prat L, Martínez-Vicente M, Perdiguero E, Ortet L, Rodríguez-Ubreva J, Rebollo E, Ruiz-Bonilla V, Gutarra S, Ballestar E, Serrano AL, Sandri M, Muñoz-Cánoves P.

Nature. 2016 Jan 7;529(7584):37-42. doi: 10.1038/nature16187.

PMID:
26738589
16.

Monozygotic twins discordant for common variable immunodeficiency reveal impaired DNA demethylation during naïve-to-memory B-cell transition.

Rodríguez-Cortez VC, Del Pino-Molina L, Rodríguez-Ubreva J, Ciudad L, Gómez-Cabrero D, Company C, Urquiza JM, Tegnér J, Rodríguez-Gallego C, López-Granados E, Ballestar E.

Nat Commun. 2015 Jun 17;6:7335. doi: 10.1038/ncomms8335.

17.

Genetics: Insights into RA pathogenesis from DNA methylome analysis.

Ballestar E.

Nat Rev Rheumatol. 2015 Jul;11(7):386-8. doi: 10.1038/nrrheum.2015.66. Epub 2015 May 19. No abstract available.

PMID:
25986718
18.

Hepatic glycogenosis: An underdiagnosed complication of diabetes mellitus?

Julián MT, Alonso N, Ojanguren I, Pizarro E, Ballestar E, Puig-Domingo M.

World J Diabetes. 2015 Mar 15;6(2):321-5. doi: 10.4239/wjd.v6.i2.321. Review.

19.

NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation.

de la Rica L, García-Gómez A, Comet NR, Rodríguez-Ubreva J, Ciudad L, Vento-Tormo R, Company C, Álvarez-Errico D, García M, Gómez-Vaquero C, Ballestar E.

Genome Biol. 2015 Jan 5;16:2. doi: 10.1186/s13059-014-0561-5.

20.

Epigenetic control of myeloid cell differentiation, identity and function.

Álvarez-Errico D, Vento-Tormo R, Sieweke M, Ballestar E.

Nat Rev Immunol. 2015 Jan;15(1):7-17. doi: 10.1038/nri3777. Review.

PMID:
25534619
21.

Gains of DNA methylation in myeloid terminal differentiation are dispensable for gene silencing but influence the differentiated phenotype.

Vento-Tormo R, Álvarez-Errico D, Rodríguez-Ubreva J, Ballestar E.

FEBS J. 2015 May;282(9):1815-25. doi: 10.1111/febs.13045. Epub 2014 Oct 7.

22.

NF-κB directly mediates epigenetic deregulation of common microRNAs in Epstein-Barr virus-mediated transformation of B-cells and in lymphomas.

Vento-Tormo R, Rodríguez-Ubreva J, Lisio LD, Islam AB, Urquiza JM, Hernando H, López-Bigas N, Shannon-Lowe C, Martínez N, Montes-Moreno S, Piris MA, Ballestar E.

Nucleic Acids Res. 2014;42(17):11025-39. doi: 10.1093/nar/gku826. Epub 2014 Sep 8.

23.

Data integration in the era of omics: current and future challenges.

Gomez-Cabrero D, Abugessaisa I, Maier D, Teschendorff A, Merkenschlager M, Gisel A, Ballestar E, Bongcam-Rudloff E, Conesa A, Tegnér J.

BMC Syst Biol. 2014;8 Suppl 2:I1. doi: 10.1186/1752-0509-8-S2-I1. Epub 2014 Mar 13. Review.

24.

Geriatric muscle stem cells switch reversible quiescence into senescence.

Sousa-Victor P, Gutarra S, García-Prat L, Rodriguez-Ubreva J, Ortet L, Ruiz-Bonilla V, Jardí M, Ballestar E, González S, Serrano AL, Perdiguero E, Muñoz-Cánoves P.

Nature. 2014 Feb 20;506(7488):316-21. doi: 10.1038/nature13013. Epub 2014 Feb 12.

PMID:
24522534
25.

C/EBPa-mediated activation of microRNAs 34a and 223 inhibits Lef1 expression to achieve efficient reprogramming into macrophages.

Rodriguez-Ubreva J, Ciudad L, van Oevelen C, Parra M, Graf T, Ballestar E.

Mol Cell Biol. 2014 Mar;34(6):1145-57. doi: 10.1128/MCB.01487-13. Epub 2014 Jan 13.

26.

Chromatin immunoprecipitation.

Rodríguez-Ubreva J, Ballestar E.

Methods Mol Biol. 2014;1094:309-18. doi: 10.1007/978-1-62703-706-8_24.

PMID:
24162998
27.

Epstein-Barr virus-mediated transformation of B cells induces global chromatin changes independent to the acquisition of proliferation.

Hernando H, Islam AB, Rodríguez-Ubreva J, Forné I, Ciudad L, Imhof A, Shannon-Lowe C, Ballestar E.

Nucleic Acids Res. 2014 Jan;42(1):249-63. doi: 10.1093/nar/gkt886. Epub 2013 Oct 3.

28.

PU.1 target genes undergo Tet2-coupled demethylation and DNMT3b-mediated methylation in monocyte-to-osteoclast differentiation.

de la Rica L, Rodríguez-Ubreva J, García M, Islam AB, Urquiza JM, Hernando H, Christensen J, Helin K, Gómez-Vaquero C, Ballestar E.

Genome Biol. 2013;14(9):R99.

29.

The B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion.

Hernando H, Shannon-Lowe C, Islam AB, Al-Shahrour F, Rodríguez-Ubreva J, Rodríguez-Cortez VC, Javierre BM, Mangas C, Fernández AF, Parra M, Delecluse HJ, Esteller M, López-Granados E, Fraga MF, López-Bigas N, Ballestar E.

Genome Biol. 2013 Jan 15;14(1):R3. doi: 10.1186/gb-2013-14-1-r3.

30.

Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression.

de la Rica L, Urquiza JM, Gómez-Cabrero D, Islam AB, López-Bigas N, Tegnér J, Toes RE, Ballestar E.

J Autoimmun. 2013 Mar;41:6-16. doi: 10.1016/j.jaut.2012.12.005. Epub 2013 Jan 8.

PMID:
23306098
31.

Tet2 facilitates the derepression of myeloid target genes during CEBPα-induced transdifferentiation of pre-B cells.

Kallin EM, Rodríguez-Ubreva J, Christensen J, Cimmino L, Aifantis I, Helin K, Ballestar E, Graf T.

Mol Cell. 2012 Oct 26;48(2):266-76. doi: 10.1016/j.molcel.2012.08.007. Epub 2012 Sep 13.

32.

Epigenetic regulation of PRAME in acute myeloid leukemia is different compared to CD34+ cells from healthy donors: effect of 5-AZA treatment.

Gutierrez-Cosío S, de la Rica L, Ballestar E, Santamaría C, Sánchez-Abarca LI, Caballero-Velazquez T, Blanco B, Calderón C, Herrero-Sánchez C, Carrancio S, Ciudad L, Cañizo C, San Miguel JF, Pérez-Simón JA.

Leuk Res. 2012 Jul;36(7):895-9. doi: 10.1016/j.leukres.2012.02.030. Epub 2012 Apr 13.

PMID:
22503131
33.

A DNA methylation signature associated with aberrant promoter DNA hypermethylation of DNMT3B in human colorectal cancer.

Huidobro C, Urdinguio RG, Rodríguez RM, Mangas C, Calvanese V, Martínez-Camblor P, Ferrero C, Parra-Blanco A, Rodrigo L, Obaya AJ, Suárez-Fernández L, Astudillo A, Hernando H, Ballestar E, Fernández AF, Fraga MF.

Eur J Cancer. 2012 Sep;48(14):2270-81. doi: 10.1016/j.ejca.2011.12.019. Epub 2012 Jan 13.

PMID:
22244828
34.

Environmental triggers and epigenetic deregulation in autoimmune disease.

Javierre BM, Hernando H, Ballestar E.

Discov Med. 2011 Dec;12(67):535-45. Review.

35.

Epigenomic deregulation in the immune system.

Rodriguez-Cortez VC, Hernando H, de la Rica L, Vento R, Ballestar E.

Epigenomics. 2011 Dec;3(6):697-713. doi: 10.2217/epi.11.99. Review.

PMID:
22126290
36.

Pre-B cell to macrophage transdifferentiation without significant promoter DNA methylation changes.

Rodríguez-Ubreva J, Ciudad L, Gómez-Cabrero D, Parra M, Bussmann LH, di Tullio A, Kallin EM, Tegnér J, Graf T, Ballestar E.

Nucleic Acids Res. 2012 Mar;40(5):1954-68. doi: 10.1093/nar/gkr1015. Epub 2011 Nov 15.

37.

Long-range epigenetic silencing associates with deregulation of Ikaros targets in colorectal cancer cells.

Javierre BM, Rodriguez-Ubreva J, Al-Shahrour F, Corominas M, Graña O, Ciudad L, Agirre X, Pisano DG, Valencia A, Roman-Gomez J, Calasanz MJ, Prosper F, Esteller M, Gonzalez-Sarmiento R, Ballestar E.

Mol Cancer Res. 2011 Aug;9(8):1139-51. doi: 10.1158/1541-7786.MCR-10-0515. Epub 2011 Jul 7. Erratum in: Mol Cancer Res. 2011 Oct;9(10):1429-32.

38.

An introduction to epigenetics.

Ballestar E.

Adv Exp Med Biol. 2011;711:1-11. Review.

PMID:
21627038
39.

Epigenetic contributions in autoimmune disease. Preface.

Ballestar E.

Adv Exp Med Biol. 2011;711:v-vi. No abstract available.

PMID:
21627037
40.

A DNA methylation fingerprint of 1628 human samples.

Fernandez AF, Assenov Y, Martin-Subero JI, Balint B, Siebert R, Taniguchi H, Yamamoto H, Hidalgo M, Tan AC, Galm O, Ferrer I, Sanchez-Cespedes M, Villanueva A, Carmona J, Sanchez-Mut JV, Berdasco M, Moreno V, Capella G, Monk D, Ballestar E, Ropero S, Martinez R, Sanchez-Carbayo M, Prosper F, Agirre X, Fraga MF, Graña O, Perez-Jurado L, Mora J, Puig S, Prat J, Badimon L, Puca AA, Meltzer SJ, Lengauer T, Bridgewater J, Bock C, Esteller M.

Genome Res. 2012 Feb;22(2):407-19. doi: 10.1101/gr.119867.110. Epub 2011 May 25.

41.

Epigenetic alterations in autoimmune rheumatic diseases.

Ballestar E.

Nat Rev Rheumatol. 2011 May;7(5):263-71. doi: 10.1038/nrrheum.2011.16. Epub 2011 Feb 22. Review.

PMID:
21343899
42.

Dioxin receptor and SLUG transcription factors regulate the insulator activity of B1 SINE retrotransposons via an RNA polymerase switch.

Román AC, González-Rico FJ, Moltó E, Hernando H, Neto A, Vicente-Garcia C, Ballestar E, Gómez-Skarmeta JL, Vavrova-Anderson J, White RJ, Montoliu L, Fernández-Salguero PM.

Genome Res. 2011 Mar;21(3):422-32. doi: 10.1101/gr.111203.110. Epub 2011 Feb 3.

43.

The p38 SAPK is recruited to chromatin via its interaction with transcription factors.

Ferreiro I, Barragan M, Gubern A, Ballestar E, Joaquin M, Posas F.

J Biol Chem. 2010 Oct 8;285(41):31819-28. doi: 10.1074/jbc.M110.155846. Epub 2010 Aug 3.

44.

A role for methyl-CpG binding domain protein 2 in the modulation of the estrogen response of pS2/TFF1 gene.

Chatagnon A, Ballestar E, Esteller M, Dante R.

PLoS One. 2010 Mar 12;5(3):e9665. doi: 10.1371/journal.pone.0009665.

45.

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus.

Javierre BM, Fernandez AF, Richter J, Al-Shahrour F, Martin-Subero JI, Rodriguez-Ubreva J, Berdasco M, Fraga MF, O'Hanlon TP, Rider LG, Jacinto FV, Lopez-Longo FJ, Dopazo J, Forn M, Peinado MA, Carreño L, Sawalha AH, Harley JB, Siebert R, Esteller M, Miller FW, Ballestar E.

Genome Res. 2010 Feb;20(2):170-9. doi: 10.1101/gr.100289.109. Epub 2009 Dec 22.

46.

Epigenetic regulation of myogenesis.

Perdiguero E, Sousa-Victor P, Ballestar E, Muñoz-Cánoves P.

Epigenetics. 2009 Nov 16;4(8):541-50. Epub 2009 Nov 5. Review.

PMID:
20009536
47.

Epigenetic signatures associated with different levels of differentiation potential in human stem cells.

Aranda P, Agirre X, Ballestar E, Andreu EJ, Román-Gómez J, Prieto I, Martín-Subero JI, Cigudosa JC, Siebert R, Esteller M, Prosper F.

PLoS One. 2009 Nov 13;4(11):e7809. doi: 10.1371/journal.pone.0007809.

48.

A robust and highly efficient immune cell reprogramming system.

Bussmann LH, Schubert A, Vu Manh TP, De Andres L, Desbordes SC, Parra M, Zimmermann T, Rapino F, Rodriguez-Ubreva J, Ballestar E, Graf T.

Cell Stem Cell. 2009 Nov 6;5(5):554-66. doi: 10.1016/j.stem.2009.10.004.

49.

Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting.

Sánchez-Abarca LI, Gutierrez-Cosio S, Santamaría C, Caballero-Velazquez T, Blanco B, Herrero-Sánchez C, García JL, Carrancio S, Hernández-Campo P, González FJ, Flores T, Ciudad L, Ballestar E, Del Cañizo C, San Miguel JF, Pérez-Simon JA.

Blood. 2010 Jan 7;115(1):107-21. doi: 10.1182/blood-2009-03-210393. Epub 2009 Nov 3.

50.

Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies.

Taniguchi H, Fernández AF, Setién F, Ropero S, Ballestar E, Villanueva A, Yamamoto H, Imai K, Shinomura Y, Esteller M.

Cancer Res. 2009 Nov 1;69(21):8447-54. doi: 10.1158/0008-5472.CAN-09-0551. Epub 2009 Oct 27.

Supplemental Content

Loading ...
Support Center