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Items: 1 to 50 of 121

1.

A role for APP in Wnt signalling links synapse loss with β-amyloid production.

Elliott C, Rojo AI, Ribe E, Broadstock M, Xia W, Morin P, Semenov M, Baillie G, Cuadrado A, Al-Shawi R, Ballard CG, Simons P, Killick R.

Transl Psychiatry. 2018 Sep 20;8(1):179. doi: 10.1038/s41398-018-0231-6.

2.

Ras-ERK-ETS inhibition alleviates neuronal mitochondrial dysfunction by reprogramming mitochondrial retrograde signaling.

Duncan OF, Granat L, Ranganathan R, Singh VK, Mazaud D, Fanto M, Chambers D, Ballard CG, Bateman JM.

PLoS Genet. 2018 Jul 30;14(7):e1007567. doi: 10.1371/journal.pgen.1007567. eCollection 2018 Jul.

3.

Novel Treatment of Cryptococcal Meningitis via Neurapheresis Therapy.

Smilnak GJ, Charalambous LT, Cutshaw D, Premji AM, Giamberardino CD, Ballard CG, Bartuska AP, Ejikeme TU, Sheng H, Verbick LZ, Hedstrom BA, Pagadala PC, McCabe AR, Perfect JR, Lad SP.

J Infect Dis. 2018 Aug 24;218(7):1147-1154. doi: 10.1093/infdis/jiy286.

4.

Mitochondrial Translocase of the Outer Membrane Alterations May Underlie Dysfunctional Oxidative Phosphorylation in Alzheimer's Disease.

Chai YL, Xing H, Chong JR, Francis PT, Ballard CG, Chen CP, Lai MKP.

J Alzheimers Dis. 2018;61(2):793-801. doi: 10.3233/JAD-170613.

PMID:
29254089
5.

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium.

McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K.

Neurology. 2017 Jul 4;89(1):88-100. doi: 10.1212/WNL.0000000000004058. Epub 2017 Jun 7. Review.

6.

Increased Transforming Growth Factor β2 in the Neocortex of Alzheimer's Disease and Dementia with Lewy Bodies is Correlated with Disease Severity and Soluble Aβ42 Load.

Chong JR, Chai YL, Lee JH, Howlett D, Attems J, Ballard CG, Aarsland D, Francis PT, Chen CP, Lai MK.

J Alzheimers Dis. 2017;56(1):157-166. doi: 10.3233/JAD-160781.

PMID:
27911312
7.

Muscarinic M1 Receptor Coupling to G-protein is Intact in Parkinson's Disease Dementia.

Lee JH, Francis PT, Ballard CG, Aarsland D, Kalaria RN, Wong PT, Chen CP, Lai MK.

J Parkinsons Dis. 2016 Oct 19;6(4):733-739.

PMID:
27662332
8.

Increased phosphorylation of collapsin response mediator protein-2 at Thr514 correlates with β-amyloid burden and synaptic deficits in Lewy body dementias.

Xing H, Lim YA, Chong JR, Lee JH, Aarsland D, Ballard CG, Francis PT, Chen CP, Lai MK.

Mol Brain. 2016 Sep 8;9(1):84. doi: 10.1186/s13041-016-0264-9.

9.

Dementia in Parkinson's disease is associated with enhanced mitochondrial complex I deficiency.

Gatt AP, Duncan OF, Attems J, Francis PT, Ballard CG, Bateman JM.

Mov Disord. 2016 Mar;31(3):352-9. doi: 10.1002/mds.26513. Epub 2016 Feb 8.

PMID:
26853899
10.

Decreased Levels of VAMP2 and Monomeric Alpha-Synuclein Correlate with Duration of Dementia.

Vallortigara J, Whitfield D, Quelch W, Alghamdi A, Howlett D, Hortobágyi T, Johnson M, Attems J, O'Brien JT, Thomas A, Ballard CG, Aarsland D, Francis PT.

J Alzheimers Dis. 2016;50(1):101-10. doi: 10.3233/JAD-150707.

PMID:
26639969
11.

Stage-specific changes in neurogenic and glial markers in Alzheimer's disease.

Ekonomou A, Savva GM, Brayne C, Forster G, Francis PT, Johnson M, Perry EK, Attems J, Somani A, Minger SL, Ballard CG; Medical Research Council Cognitive Function and Ageing Neuropathology Study.

Biol Psychiatry. 2015 Apr 15;77(8):711-9. doi: 10.1016/j.biopsych.2014.05.021. Epub 2014 Jun 9.

PMID:
25022604
12.

Dynamin protein in stroke and vascular dementia.

Mulugeta E, Vallortigara J, Francis PT, Hye A, Kalaria RN, Perry EK, Lovestone S, Ballard CG.

Neurosci Lett. 2014 Mar 20;563:118-22. doi: 10.1016/j.neulet.2014.01.045. Epub 2014 Jan 31.

PMID:
24486840
13.

Decreased immunoreactivities of neocortical AMPA receptor subunits correlate with motor disability in Lewy body dementias.

Mohamed NE, Howlett DR, Ma L, Francis PT, Aarsland D, Ballard CG, McKeith IG, Chen CP, Lai MK.

J Neural Transm (Vienna). 2014 Jan;121(1):71-8. doi: 10.1007/s00702-013-1067-0. Epub 2013 Jul 12.

PMID:
23846847
14.

(123I)FP-CIT SPECT in suspected dementia with Lewy bodies: a longitudinal case study.

Siepel FJ, Rongve A, Buter TC, Beyer MK, Ballard CG, Booij J, Aarsland D.

BMJ Open. 2013 Apr 8;3(4). pii: e002642. doi: 10.1136/bmjopen-2013-002642. Print 2013. Erratum in: BMJ Open. 2015;5(7):e002642corr1.

15.

Biomarkers for dementia diagnosis: differentiating DLB and FTD may be difficult.

Aarsland D, Ballard CG.

J Neurol Neurosurg Psychiatry. 2012 Nov;83(11):1037. doi: 10.1136/jnnp-2012-303026. Epub 2012 Aug 6. No abstract available.

PMID:
22869920
16.

Proteasome inhibition leads to early loss of synaptic proteins in neuronal culture.

Bajic N, Jenner P, Ballard CG, Francis PT.

J Neural Transm (Vienna). 2012 Dec;119(12):1467-76. doi: 10.1007/s00702-012-0816-9. Epub 2012 May 17. Erratum in: J Neural Transm. 2013 Jul;120(7):1135.

PMID:
22592936
17.

Depression in Parkinson disease--epidemiology, mechanisms and management.

Aarsland D, Påhlhagen S, Ballard CG, Ehrt U, Svenningsson P.

Nat Rev Neurol. 2011 Dec 26;8(1):35-47. doi: 10.1038/nrneurol.2011.189. Review.

PMID:
22198405
18.

Increased neural progenitors in individuals with cerebral small vessel disease.

Ekonomou A, Johnson M, Perry RH, Perry EK, Kalaria RN, Minger SL, Ballard CG.

Neuropathol Appl Neurobiol. 2012 Jun;38(4):344-53. doi: 10.1111/j.1365-2990.2011.01224.x.

PMID:
21988073
19.

Genetic associations of autopsy-confirmed vascular dementia subtypes.

Jones EL, Kalaria RN, Sharp SI, O'Brien JT, Francis PT, Ballard CG.

Dement Geriatr Cogn Disord. 2011;31(4):247-53. doi: 10.1159/000327171. Epub 2011 Apr 7.

PMID:
21474934
20.

Antipsychotic medication is associated with selective alterations in ventricular cerebrospinal fluid Aβ 40 and tau in patients with intractable unipolar depression.

Clarke NA, Hartmann T, Jones EL, Ballard CG, Francis PT.

Int J Geriatr Psychiatry. 2011 Dec;26(12):1283-91. doi: 10.1002/gps.2678. Epub 2011 Feb 9.

PMID:
21308788
21.

An Intron 7 Polymorphism in APP Affects the Age of Onset of Dementia in Down Syndrome.

Jones EL, Ballard CG, Prasher VP, Arno M, Tyrer S, Moore B, Hanney ML.

Int J Alzheimers Dis. 2010 Dec 20;2011:929102. doi: 10.4061/2011/929102.

22.

Vesicular glutamate transporter and cognition in stroke: a case-control autopsy study.

Kirvell SL, Elliott MS, Kalaria RN, Hortobágyi T, Ballard CG, Francis PT.

Neurology. 2010 Nov 16;75(20):1803-9. doi: 10.1212/WNL.0b013e3181fd6328.

23.

CSF α-synuclein as a diagnostic biomarker for Parkinson disease and related dementias.

Ballard CG, Jones EL.

Neurology. 2010 Nov 16;75(20):1760-1. doi: 10.1212/WNL.0b013e3181fd6393. Epub 2010 Oct 20. No abstract available.

PMID:
20962288
24.

NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivors.

Morris CM, Ballard CG, Allan L, Rowan E, Stephens S, Firbank M, Ford GA, Kenny RA, O'Brien JT, Kalaria RN.

Neurobiol Aging. 2011 Mar;32(3):554.e1-6. doi: 10.1016/j.neurobiolaging.2010.06.012. Epub 2010 Aug 5.

PMID:
20691505
25.

Neurogenic marker abnormalities in the hippocampus in dementia with Lewy bodies.

Johnson M, Ekonomou A, Hobbs C, Ballard CG, Perry RH, Perry EK.

Hippocampus. 2011 Oct;21(10):1126-36. doi: 10.1002/hipo.20826. Epub 2010 Jul 21.

PMID:
20665591
26.

Putting brain training to the test.

Owen AM, Hampshire A, Grahn JA, Stenton R, Dajani S, Burns AS, Howard RJ, Ballard CG.

Nature. 2010 Jun 10;465(7299):775-8. doi: 10.1038/nature09042.

27.

Increased neural progenitors in vascular dementia.

Ekonomou A, Ballard CG, Pathmanaban ON, Perry RH, Perry EK, Kalaria RN, Minger SL.

Neurobiol Aging. 2011 Dec;32(12):2152-61. doi: 10.1016/j.neurobiolaging.2010.01.007. Epub 2010 Feb 5.

PMID:
20138403
28.

Parkinson disease with dementia: comparing patients with and without Alzheimer pathology.

Sabbagh MN, Adler CH, Lahti TJ, Connor DJ, Vedders L, Peterson LK, Caviness JN, Shill HA, Sue LI, Ziabreva I, Perry E, Ballard CG, Aarsland D, Walker DG, Beach TG.

Alzheimer Dis Assoc Disord. 2009 Jul-Sep;23(3):295-7. doi: 10.1097/WAD.0b013e31819c5ef4.

29.

Choline acetyltransferase activity in vascular dementia and stroke.

Sharp SI, Francis PT, Elliott MS, Kalaria RN, Bajic N, Hortobagyi T, Ballard CG.

Dement Geriatr Cogn Disord. 2009;28(3):233-8. doi: 10.1159/000239235. Epub 2009 Sep 17.

PMID:
19776575
30.

Management of agitation and aggression associated with Alzheimer disease.

Ballard CG, Gauthier S, Cummings JL, Brodaty H, Grossberg GT, Robert P, Lyketsos CG.

Nat Rev Neurol. 2009 May;5(5):245-55. doi: 10.1038/nrneurol.2009.39. Review.

PMID:
19488082
31.

Incidence and prediction of falls in dementia: a prospective study in older people.

Allan LM, Ballard CG, Rowan EN, Kenny RA.

PLoS One. 2009;4(5):e5521. doi: 10.1371/journal.pone.0005521. Epub 2009 May 13.

32.

Increased binding to 5-HT1A and 5-HT2A receptors is associated with large vessel infarction and relative preservation of cognition.

Elliott MS, Ballard CG, Kalaria RN, Perry R, Hortobágyi T, Francis PT.

Brain. 2009 Jul;132(Pt 7):1858-65. doi: 10.1093/brain/awp069. Epub 2009 May 11.

PMID:
19433439
33.

Cholinesterase inhibitors may increase phosphorylated tau in Alzheimer's disease.

Chalmers KA, Wilcock GK, Vinters HV, Perry EK, Perry R, Ballard CG, Love S.

J Neurol. 2009 May;256(5):717-20. doi: 10.1007/s00415-009-5000-2. Epub 2009 Feb 25.

34.

Amyloid beta concentrations in older people with Down syndrome and dementia.

Jones EL, Hanney M, Francis PT, Ballard CG.

Neurosci Lett. 2009 Feb 20;451(2):162-4. doi: 10.1016/j.neulet.2008.12.030. Epub 2008 Dec 24.

PMID:
19111900
35.

Cortical serotonin 1A receptor levels are associated with depression in patients with dementia with Lewy bodies and Parkinson's disease dementia.

Sharp SI, Ballard CG, Ziabreva I, Piggott MA, Perry RH, Perry EK, Aarsland D, Ehrt U, Larsen JP, Francis PT.

Dement Geriatr Cogn Disord. 2008;26(4):330-8. doi: 10.1159/000161058. Epub 2008 Oct 8.

PMID:
18841018
36.

The extended tau haplotype and the age of onset of dementia in Down syndrome.

Jones EL, Margallo-Lana M, Prasher VP, Ballard CG.

Dement Geriatr Cogn Disord. 2008;26(3):199-202. doi: 10.1159/000152044. Epub 2008 Sep 3.

PMID:
18765933
37.

Butyrylcholinesterase K variant associated with higher enzyme activity in the temporal cortex of elderly patients.

Tasker A, Ballard CG, Joachim C, Warden DR, Okello EJ, Perry RH, Khan N, Smith AD, Lehmann DJ, Perry EK.

Neurosci Lett. 2008 Sep 19;442(3):297-9. doi: 10.1016/j.neulet.2008.07.023. Epub 2008 Jul 12.

PMID:
18640242
38.

An extract of Salvia (sage) with anticholinesterase properties improves memory and attention in healthy older volunteers.

Scholey AB, Tildesley NT, Ballard CG, Wesnes KA, Tasker A, Perry EK, Kennedy DO.

Psychopharmacology (Berl). 2008 May;198(1):127-39. doi: 10.1007/s00213-008-1101-3. Epub 2008 Mar 19.

PMID:
18350281
39.

Inflammatory mediators in the frontal lobe of patients with mixed and vascular dementia.

Mulugeta E, Molina-Holgado F, Elliott MS, Hortobagyi T, Perry R, Kalaria RN, Ballard CG, Francis PT.

Dement Geriatr Cogn Disord. 2008;25(3):278-86. doi: 10.1159/000118633. Epub 2008 Feb 26.

PMID:
18303264
40.
41.

Donepezil for the treatment of agitation in Alzheimer's disease.

Howard RJ, Juszczak E, Ballard CG, Bentham P, Brown RG, Bullock R, Burns AS, Holmes C, Jacoby R, Johnson T, Knapp M, Lindesay J, O'Brien JT, Wilcock G, Katona C, Jones RW, DeCesare J, Rodger M; CALM-AD Trial Group.

N Engl J Med. 2007 Oct 4;357(14):1382-92.

42.

Selective loss of dopamine D2 receptors in temporal cortex in dementia with Lewy bodies, association with cognitive decline.

Piggott MA, Ballard CG, Rowan E, Holmes C, McKeith IG, Jaros E, Perry RH, Perry EK.

Synapse. 2007 Nov;61(11):903-11.

PMID:
17663455
43.

The period of hypotension following orthostatic challenge is prolonged in dementia with Lewy bodies.

Andersson M, Hansson O, Minthon L, Ballard CG, Londos E.

Int J Geriatr Psychiatry. 2008 Feb;23(2):192-8.

PMID:
17621385
44.

Cholinesterase inhibitors reduce cortical Abeta in dementia with Lewy bodies.

Ballard CG, Chalmers KA, Todd C, McKeith IG, O'Brien JT, Wilcock G, Love S, Perry EK.

Neurology. 2007 May 15;68(20):1726-9.

PMID:
17502555
45.

Endogenous neurogenesis in the human brain following cerebral infarction.

Minger SL, Ekonomou A, Carta EM, Chinoy A, Perry RH, Ballard CG.

Regen Med. 2007 Jan;2(1):69-74.

PMID:
17465777
46.
47.

Subtle attentional deficits in the absence of dementia are associated with an increased risk of post-operative delirium.

Lowery DP, Wesnes K, Ballard CG.

Dement Geriatr Cogn Disord. 2007;23(6):390-4. Epub 2007 Mar 29.

PMID:
17396030
48.

Autonomic dysfunction in dementia.

Allan LM, Ballard CG, Allen J, Murray A, Davidson AW, McKeith IG, Kenny RA.

J Neurol Neurosurg Psychiatry. 2007 Jul;78(7):671-7. Epub 2006 Dec 18.

49.

Quantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-beta(42) peptide in vascular dementia.

Lewis H, Beher D, Cookson N, Oakley A, Piggott M, Morris CM, Jaros E, Perry R, Ince P, Kenny RA, Ballard CG, Shearman MS, Kalaria RN.

Neuropathol Appl Neurobiol. 2006 Apr;32(2):103-18.

PMID:
16599940
50.

Thalamic D2 receptors in dementia with Lewy bodies, Parkinson's disease, and Parkinson's disease dementia.

Piggott MA, Ballard CG, Dickinson HO, McKeith IG, Perry RH, Perry EK.

Int J Neuropsychopharmacol. 2007 Apr;10(2):231-44. Epub 2006 Feb 1.

PMID:
16448581

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