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Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease: A Randomized Clinical Trial.

Howard R, Zubko O, Bradley R, Harper E, Pank L, O'Brien J, Fox C, Tabet N, Livingston G, Bentham P, McShane R, Burns A, Ritchie C, Reeves S, Lovestone S, Ballard C, Noble W, Nilforooshan R, Wilcock G, Gray R; Minocycline in Alzheimer Disease Efficacy (MADE) Trialist Group.

JAMA Neurol. 2019 Nov 18. doi: 10.1001/jamaneurol.2019.3762. [Epub ahead of print]


Cost-Effectiveness of Dementia Care Mapping in Care-Home Settings: Evaluation of a Randomised Controlled Trial.

Meads DM, Martin A, Griffiths A, Kelley R, Creese B, Robinson L, McDermid J, Walwyn R, Ballard C, Surr CA.

Appl Health Econ Health Policy. 2019 Nov 8. doi: 10.1007/s40258-019-00531-1. [Epub ahead of print]


Alzheimer's Disease Progression in the 5×FAD Mouse Captured with a Multiplex Gene Expression Array.

Gatt A, Whitfield DR, Ballard C, Doherty P, Williams G.

J Alzheimers Dis. 2019 Oct 29. doi: 10.3233/JAD-190805. [Epub ahead of print]


Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease.

Creese B, Vassos E, Bergh S, Athanasiu L, Johar I, Rongve A, Medbøen IT, Vasconcelos Da Silva M, Aakhus E, Andersen F, Bettella F, Braekhus A, Djurovic S, Paroni G, Proitsi P, Saltvedt I, Seripa D, Stordal E, Fladby T, Aarsland D, Andreassen OA, Ballard C, Selbaek G; AddNeuroMed consortium and the Alzheimer’s Disease Neuroimaging Initiative.

Transl Psychiatry. 2019 Oct 22;9(1):273. doi: 10.1038/s41398-019-0592-5.


Effects of Polyphenol-Rich Fruit Extracts on Diet-Induced Obesity in Rodents: Systematic Review and Meta-Analysis.

Ballard CR, Galvão TF, Cazarin CBB, Maróstica MR.

Curr Pharm Des. 2019;25(32):3484-3497. doi: 10.2174/1381612824666191010170100.


Measuring the Effectiveness of Safety Warnings on the Risk of Stroke in Older Antipsychotic Users: A Nationwide Cohort Study in Two Large Electronic Medical Records Databases in the United Kingdom and Italy.

Sultana J, Fontana A, Giorgianni F, Tillati S, Cricelli C, Pasqua A, Patorno E, Ballard C, Sturkenboom M, Trifirò G.

Drug Saf. 2019 Dec;42(12):1471-1485. doi: 10.1007/s40264-019-00860-z.


Profile of mild behavioral impairment and factor structure of the Mild Behavioral Impairment Checklist in cognitively normal older adults.

Creese B, Griffiths A, Brooker H, Corbett A, Aarsland D, Ballard C, Ismail Z.

Int Psychogeriatr. 2019 Sep 17:1-13. doi: 10.1017/S1041610219001200. [Epub ahead of print]


The individual course of neuropsychiatric symptoms in people with Alzheimer's and Lewy body dementia: 12-year longitudinal cohort study.

Vik-Mo AO, Giil LM, Borda MG, Ballard C, Aarsland D.

Br J Psychiatry. 2019 Sep 11:1-6. doi: 10.1192/bjp.2019.195. [Epub ahead of print]


Study protocol: ASCRIBED: the impact of Acute SystematiC inflammation upon cerebRospinal fluId and blood BiomarkErs of brain inflammation and injury in dementia: a study in acute hip fracture patients.

Leavey N, Hammond SP, Shepstone L, Cross J, Zetterberg H, Cunningham C, MacLullich A, Leiv Otto Watne, Minihane AM, Ballard C, Knapskog AB, Hall R, Howard G, Hammond M, Fox C.

BMC Neurol. 2019 Sep 7;19(1):223. doi: 10.1186/s12883-019-1447-7.


Drug repurposing for Alzheimer's disease based on transcriptional profiling of human iPSC-derived cortical neurons.

Williams G, Gatt A, Clarke E, Corcoran J, Doherty P, Chambers D, Ballard C.

Transl Psychiatry. 2019 Sep 6;9(1):220. doi: 10.1038/s41398-019-0555-x.


Influence of a novel bm3 corn silage hybrid with floury kernel genetics on lactational performance and feed efficiency of Holstein cows.

Coons EM, Fredin SM, Cotanch KW, Dann HM, Ballard CS, Brouillette JP, Grant RJ.

J Dairy Sci. 2019 Nov;102(11):9814-9826. doi: 10.3168/jds.2019-16786. Epub 2019 Aug 22.


Small vessel disease pathological changes in neurodegenerative and vascular dementias concomitant with autonomic dysfunction.

Hase Y, Polvikoski TM, Firbank MJ, Craggs LJL, Hawthorne E, Platten C, Stevenson W, Deramecourt V, Ballard C, Kenny RA, Perry RH, Ince P, Carare RO, Allan LM, Horsburgh K, Kalaria RN.

Brain Pathol. 2019 Jul 29. doi: 10.1111/bpa.12769. [Epub ahead of print]


Associations of Awareness of Age-Related Change With Emotional and Physical Well-being: A Systematic Review and Meta-analysis.

Sabatini S, Silarova B, Martyr A, Collins R, Ballard C, Anstey KJ, Kim S, Clare L.

Gerontologist. 2019 Jul 27. pii: gnz101. doi: 10.1093/geront/gnz101. [Epub ahead of print]


Postmortem Cortical Transcriptomics of Lewy Body Dementia Reveal Mitochondrial Dysfunction and Lack of Neuroinflammation.

Rajkumar AP, Bidkhori G, Shoaie S, Clarke E, Morrin H, Hye A, Williams G, Ballard C, Francis P, Aarsland D.

Am J Geriatr Psychiatry. 2020 Jan;28(1):75-86. doi: 10.1016/j.jagp.2019.06.007. Epub 2019 Jun 24.


Age-related neurochemical and behavioural changes in D409V/WT GBA1 mouse: Relevance to lewy body dementia.

Clarke E, Jantrachotechatchawan C, Buhidma Y, Broadstock M, Yu L, Howlett D, Aarsland D, Ballard C, Francis PT.

Neurochem Int. 2019 Oct;129:104502. doi: 10.1016/j.neuint.2019.104502. Epub 2019 Jul 9.


Tip of the Iceberg: Assessing the Global Socioeconomic Costs of Alzheimer's Disease and Related Dementias and Strategic Implications for Stakeholders.

El-Hayek YH, Wiley RE, Khoury CP, Daya RP, Ballard C, Evans AR, Karran M, Molinuevo JL, Norton M, Atri A.

J Alzheimers Dis. 2019;70(2):323-341. doi: 10.3233/JAD-190426. Review.


Enrichment factors for clinical trials in mild-to-moderate Alzheimer's disease.

Ballard C, Atri A, Boneva N, Cummings JL, Frölich L, Molinuevo JL, Tariot PN, Raket LL.

Alzheimers Dement (N Y). 2019 May 20;5:164-174. doi: 10.1016/j.trci.2019.04.001. eCollection 2019.


Commentary: Opportunities for Combination Trials.

Ballard C, Corbett A.

J Prev Alzheimers Dis. 2019;6(3):177-178. doi: 10.14283/jpad.2019.17. No abstract available.


Analgesic treatments in people with dementia - how safe are they? A systematic review.

Erdal A, Ballard C, Vahia IV, Husebo BS.

Expert Opin Drug Saf. 2019 Jun;18(6):511-522. doi: 10.1080/14740338.2019.1614166. Epub 2019 May 16.


Predictors of Hepatitis C Treatment Failure After Using Direct-Acting Antivirals in People Living With Human Immunodeficiency Virus.

Cachay ER, Mena A, Morano L, Benitez L, Maida I, Ballard C, Hill L, Torriani F, Castro A, Dore E, Castro S, de Mendoza Fernández C, Soriano V, Mathews WC; HCV-TREN Cohort.

Open Forum Infect Dis. 2019 Feb 11;6(3):ofz070. doi: 10.1093/ofid/ofz070. eCollection 2019 Mar.


Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study).

Femminella GD, Frangou E, Love SB, Busza G, Holmes C, Ritchie C, Lawrence R, McFarlane B, Tadros G, Ridha BH, Bannister C, Walker Z, Archer H, Coulthard E, Underwood BR, Prasanna A, Koranteng P, Karim S, Junaid K, McGuinness B, Nilforooshan R, Macharouthu A, Donaldson A, Thacker S, Russell G, Malik N, Mate V, Knight L, Kshemendran S, Harrison J, Brooks DJ, Passmore AP, Ballard C, Edison P.

Trials. 2019 Apr 3;20(1):191. doi: 10.1186/s13063-019-3259-x.


Deep and Frequent Phenotyping study protocol: an observational study in prodromal Alzheimer's disease.

Koychev I, Lawson J, Chessell T, Mackay C, Gunn R, Sahakian B, Rowe JB, Thomas AJ, Rochester L, Chan D, Tom B, Malhotra P, Ballard C, Chessell I, Ritchie CW, Raymont V, Leroi I, Lengyel I, Murray M, Thomas DL, Gallacher J, Lovestone S.

BMJ Open. 2019 Mar 23;9(3):e024498. doi: 10.1136/bmjopen-2018-024498.


Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults.

Creese B, Brooker H, Ismail Z, Wesnes KA, Hampshire A, Khan Z, Megalogeni M, Corbett A, Aarsland D, Ballard C.

Am J Geriatr Psychiatry. 2019 Aug;27(8):823-834. doi: 10.1016/j.jagp.2019.01.215. Epub 2019 Feb 2.


The relationship between the frequency of number-puzzle use and baseline cognitive function in a large online sample of adults aged 50 and over.

Brooker H, Wesnes KA, Ballard C, Hampshire A, Aarsland D, Khan Z, Stenton R, Megalogeni M, Corbett A.

Int J Geriatr Psychiatry. 2019 Jul;34(7):932-940. doi: 10.1002/gps.5085. Epub 2019 Feb 28.


Expression of neurogenic markers in Alzheimer's disease: a systematic review and metatranscriptional analysis.

Gatt A, Lee H, Williams G, Thuret S, Ballard C.

Neurobiol Aging. 2019 Apr;76:166-180. doi: 10.1016/j.neurobiolaging.2018.12.016. Epub 2019 Jan 8.


Treatment Combinations for Alzheimer's Disease: Current and Future Pharmacotherapy Options.

Cummings JL, Tong G, Ballard C.

J Alzheimers Dis. 2019;67(3):779-794. doi: 10.3233/JAD-180766. Review.


Open-Label, Multicenter, Phase III Extension Study of Idalopirdine as Adjunctive to Donepezil for the Treatment of Mild-Moderate Alzheimer's Disease.

Frölich L, Atri A, Ballard C, Tariot PN, Molinuevo JL, Boneva N, Geist MA, Raket LL, Cummings JL.

J Alzheimers Dis. 2019;67(1):303-313. doi: 10.3233/JAD-180595.


The Effect of a Multicomponent Intervention on Quality of Life in Residents of Nursing Homes: A Randomized Controlled Trial (COSMOS).

Husebø BS, Ballard C, Aarsland D, Selbaek G, Slettebo DD, Gulla C, Aasmul I, Habiger T, Elvegaard T, Testad I, Flo E.

J Am Med Dir Assoc. 2019 Mar;20(3):330-339. doi: 10.1016/j.jamda.2018.11.006. Epub 2019 Jan 7.


Survival time and differences between dementia with Lewy bodies and Alzheimer's disease following diagnosis: A meta-analysis of longitudinal studies.

Mueller C, Soysal P, Rongve A, Isik AT, Thompson T, Maggi S, Smith L, Basso C, Stewart R, Ballard C, O'Brien JT, Aarsland D, Stubbs B, Veronese N.

Ageing Res Rev. 2019 Mar;50:72-80. doi: 10.1016/j.arr.2019.01.005. Epub 2019 Jan 6. Review.


Evaluation of powdered 0.5% chlorhexidine acetate-based postmilking teat dip compared with a foamed 1% iodine-based postmilking teat dip under cold weather conditions in northern New York.

Morrill KM, Scillieri Smith JC, Dann HM, Gauthier HM, Ballard CS.

J Dairy Sci. 2019 Mar;102(3):2507-2514. doi: 10.3168/jds.2018-15357. Epub 2019 Jan 3.


Pimavanserin in Alzheimer's Disease Psychosis: Efficacy in Patients with More Pronounced Psychotic Symptoms.

Ballard C, Youakim JM, Coate B, Stankovic S.

J Prev Alzheimers Dis. 2019;6(1):27-33. doi: 10.14283/jpad.2018.30.


Insights into globalization: comparison of patient characteristics and disease progression among geographic regions in a multinational Alzheimer's disease clinical program.

Cummings JL, Atri A, Ballard C, Boneva N, Frölich L, Molinuevo JL, Raket LL, Tariot PN.

Alzheimers Res Ther. 2018 Nov 24;10(1):116. doi: 10.1186/s13195-018-0443-2.


Improving the quality of life of care home residents with dementia: Cost-effectiveness of an optimized intervention for residents with clinically significant agitation in dementia.

Romeo R, Zala D, Knapp M, Orrell M, Fossey J, Ballard C.

Alzheimers Dement. 2019 Feb;15(2):282-291. doi: 10.1016/j.jalz.2018.08.010. Epub 2018 Nov 20.


The Incidence of Recorded Delirium Episodes Before and After Dementia Diagnosis: Differences Between Dementia With Lewy Bodies and Alzheimer's Disease.

FitzGerald JM, Perera G, Chang-Tave A, Price A, Rajkumar AP, Bhattarai M, O'Brien JT, Ballard C, Aarsland D, Stewart R, Mueller C.

J Am Med Dir Assoc. 2019 May;20(5):604-609. doi: 10.1016/j.jamda.2018.09.021. Epub 2018 Nov 15.


An online investigation of the relationship between the frequency of word puzzle use and cognitive function in a large sample of older adults.

Brooker H, Wesnes KA, Ballard C, Hampshire A, Aarsland D, Khan Z, Stenton R, McCambridge L, Corbett A.

Int J Geriatr Psychiatry. 2019 Jul;34(7):921-931. doi: 10.1002/gps.5033. Epub 2019 May 16.


Pimavanserin for Parkinson's Disease psychosis: Effects stratified by baseline cognition and use of cognitive-enhancing medications.

Espay AJ, Guskey MT, Norton JC, Coate B, Vizcarra JA, Ballard C, Factor SA, Friedman JH, Lang AE, Larsen NJ, Andersson C, Fredericks D, Weintraub D.

Mov Disord. 2018 Nov;33(11):1769-1776. doi: 10.1002/mds.27488. Epub 2018 Nov 2.


Protocol for the IDEAL-2 longitudinal study: following the experiences of people with dementia and their primary carers to understand what contributes to living well with dementia and enhances active life.

Silarova B, Nelis SM, Ashworth RM, Ballard C, Bieńkiewicz M, Henderson C, Hillman A, Hindle JV, Hughes JC, Lamont RA, Litherland R, Jones IR, Jones RW, Knapp M, Kotting P, Martyr A, Matthews FE, Morris RG, Quinn C, Regan J, Rusted JM, van den Heuvel EA, Victor CR, Wu YT, Clare L.

BMC Public Health. 2018 Oct 30;18(1):1214. doi: 10.1186/s12889-018-6129-7.


Healthy adjustment for new residents with dementia using SettleIN: A feasibility study in UK care homes.

Hayward JK, Nunez KM, Ballard C, Spector A.

Dementia (London). 2018 Oct 24:1471301218806082. doi: 10.1177/1471301218806082. [Epub ahead of print]


Pimavanserin: Potential Treatment For Dementia-Related Psychosis.

Cummings J, Ballard C, Tariot P, Owen R, Foff E, Youakim J, Norton J, Stankovic S.

J Prev Alzheimers Dis. 2018;5(4):253-258. doi: 10.14283/jpad.2018.29. Review.


Investigating the relationship between age of onset of depressive disorder and cognitive function.

Eraydin IE, Mueller C, Corbett A, Ballard C, Brooker H, Wesnes K, Aarsland D, Huntley J.

Int J Geriatr Psychiatry. 2019 Jan;34(1):38-46. doi: 10.1002/gps.4979. Epub 2018 Sep 27.


A role for APP in Wnt signalling links synapse loss with β-amyloid production.

Elliott C, Rojo AI, Ribe E, Broadstock M, Xia W, Morin P, Semenov M, Baillie G, Cuadrado A, Al-Shawi R, Ballard CG, Simons P, Killick R.

Transl Psychiatry. 2018 Sep 20;8(1):179. doi: 10.1038/s41398-018-0231-6.


Predictors of Missed Hepatitis C Intake Appointments and Failure to Establish Hepatitis C Care Among Patients Living With HIV.

Cachay ER, Hill L, Torriani F, Ballard C, Grelotti D, Aquino A, Christopher Mathews W.

Open Forum Infect Dis. 2018 Jul 31;5(7):ofy173. doi: 10.1093/ofid/ofy173. eCollection 2018 Jul.


Management of behavioral and psychological symptoms in people with Alzheimer's disease: an international Delphi consensus.

Kales HC, Lyketsos CG, Miller EM, Ballard C.

Int Psychogeriatr. 2019 Jan;31(1):83-90. doi: 10.1017/S1041610218000534. Epub 2018 Aug 2.


Ras-ERK-ETS inhibition alleviates neuronal mitochondrial dysfunction by reprogramming mitochondrial retrograde signaling.

Duncan OF, Granat L, Ranganathan R, Singh VK, Mazaud D, Fanto M, Chambers D, Ballard CG, Bateman JM.

PLoS Genet. 2018 Jul 30;14(7):e1007567. doi: 10.1371/journal.pgen.1007567. eCollection 2018 Jul.


Advanced cerebral amyloid angiopathy and small vessel disease are associated with psychosis in Alzheimer's disease.

Vik-Mo AO, Bencze J, Ballard C, Hortobágyi T, Aarsland D.

J Neurol Neurosurg Psychiatry. 2019 Jun;90(6):728-730. doi: 10.1136/jnnp-2018-318445. Epub 2018 Jul 27. No abstract available.


Executive function but not episodic memory decline associated with visual hallucinations in Parkinson's disease.

Creese B, Albertyn CP, Dworkin S, Thomas RS, Wan YM, Ballard C.

J Neuropsychol. 2018 Jul 23. doi: 10.1111/jnp.12169. [Epub ahead of print]


Impaired chronic pain-like behaviour and altered opioidergic system in the TASTPM mouse model of Alzheimer's disease.

Aman Y, Pitcher T, Ballard C, Malcangio M.

Eur J Pain. 2019 Jan;23(1):91-106. doi: 10.1002/ejp.1288. Epub 2018 Jul 30.


Course of neuropsychiatric symptoms in dementia: 5-year longitudinal study.

Vik-Mo AO, Giil LM, Ballard C, Aarsland D.

Int J Geriatr Psychiatry. 2018 Oct;33(10):1361-1369. doi: 10.1002/gps.4933. Epub 2018 Jul 6.


SIMBAD: a sequence-independent molecular-replacement pipeline.

Simpkin AJ, Simkovic F, Thomas JMH, Savko M, Lebedev A, Uski V, Ballard C, Wojdyr M, Wu R, Sanishvili R, Xu Y, Lisa MN, Buschiazzo A, Shepard W, Rigden DJ, Keegan RM.

Acta Crystallogr D Struct Biol. 2018 Jul 1;74(Pt 7):595-605. doi: 10.1107/S2059798318005752. Epub 2018 Jun 8.

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