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Items: 18


Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses.

Jaynes JM, Sable R, Ronzetti M, Bautista W, Knotts Z, Abisoye-Ogunniyan A, Li D, Calvo R, Dashnyam M, Singh A, Guerin T, White J, Ravichandran S, Kumar P, Talsania K, Chen V, Ghebremedhin A, Karanam B, Bin Salam A, Amin R, Odzorig T, Aiken T, Nguyen V, Bian Y, Zarif JC, de Groot AE, Mehta M, Fan L, Hu X, Simeonov A, Pate N, Abu-Asab M, Ferrer M, Southall N, Ock CY, Zhao Y, Lopez H, Kozlov S, de Val N, Yates CC, Baljinnyam B, Marugan J, Rudloff U.

Sci Transl Med. 2020 Feb 12;12(530). pii: eaax6337. doi: 10.1126/scitranslmed.aax6337.


Applications of Differential Scanning Fluorometry and Related Technologies in Characterization of Protein-Ligand Interactions.

Baljinnyam B, Ronzetti M, Yasgar A, Simeonov A.

Methods Mol Biol. 2020;2089:47-68. doi: 10.1007/978-1-0716-0163-1_4.


Molecular basis for activation of lecithin:cholesterol acyltransferase by a compound that increases HDL cholesterol.

Manthei KA, Yang SM, Baljinnyam B, Chang L, Glukhova A, Yuan W, Freeman LA, Maloney DJ, Schwendeman A, Remaley AT, Jadhav A, Tesmer JJ.

Elife. 2018 Nov 27;7. pii: e41604. doi: 10.7554/eLife.41604.


Testing for drug-human serum albumin binding using fluorescent probes and other methods.

Ronzetti M, Baljinnyam B, Yasgar A, Simeonov A.

Expert Opin Drug Discov. 2018 Nov;13(11):1005-1014. doi: 10.1080/17460441.2018.1534824. Epub 2018 Oct 15. Review.


Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.

Yang SM, Martinez NJ, Yasgar A, Danchik C, Johansson C, Wang Y, Baljinnyam B, Wang AQ, Xu X, Shah P, Cheff D, Wang XS, Roth J, Lal-Nag M, Dunford JE, Oppermann U, Vasiliou V, Simeonov A, Jadhav A, Maloney DJ.

J Med Chem. 2018 Jun 14;61(11):4883-4903. doi: 10.1021/acs.jmedchem.8b00270. Epub 2018 May 31.


Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors.

Rohde JM, Brimacombe KR, Liu L, Pacold ME, Yasgar A, Cheff DM, Lee TD, Rai G, Baljinnyam B, Li Z, Simeonov A, Hall MD, Shen M, Sabatini DM, Boxer MB.

Bioorg Med Chem. 2018 May 1;26(8):1727-1739. doi: 10.1016/j.bmc.2018.02.016. Epub 2018 Feb 27.


Cell Lysate-Based AlphaLISA Deubiquitinase Assay Platform for Identification of Small Molecule Inhibitors.

Ott CA, Baljinnyam B, Zakharov AV, Jadhav A, Simeonov A, Zhuang Z.

ACS Chem Biol. 2017 Sep 15;12(9):2399-2407. doi: 10.1021/acschembio.7b00543. Epub 2017 Aug 24.


Systematic mapping of WNT-FZD protein interactions reveals functional selectivity by distinct WNT-FZD pairs.

Dijksterhuis JP, Baljinnyam B, Stanger K, Sercan HO, Ji Y, Andres O, Rubin JS, Hannoush RN, Schulte G.

J Biol Chem. 2015 Mar 13;290(11):6789-98. doi: 10.1074/jbc.M114.612648. Epub 2015 Jan 20.


Secreted Frizzled-related protein potentiation versus inhibition of Wnt3a/β-catenin signaling.

Xavier CP, Melikova M, Chuman Y, Üren A, Baljinnyam B, Rubin JS.

Cell Signal. 2014 Jan;26(1):94-101. doi: 10.1016/j.cellsig.2013.09.016. Epub 2013 Sep 28.


Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling.

González-Sancho JM, Greer YE, Abrahams CL, Takigawa Y, Baljinnyam B, Lee KH, Lee KS, Rubin JS, Brown AM.

J Biol Chem. 2013 Mar 29;288(13):9428-37. doi: 10.1074/jbc.M112.448480. Epub 2013 Feb 8.


Recombinant R-spondin2 and Wnt3a up- and down-regulate novel target genes in C57MG mouse mammary epithelial cells.

Baljinnyam B, Klauzinska M, Saffo S, Callahan R, Rubin JS.

PLoS One. 2012;7(1):e29455. doi: 10.1371/journal.pone.0029455. Epub 2012 Jan 4.


Rspo2/Int7 regulates invasiveness and tumorigenic properties of mammary epithelial cells.

Klauzinska M, Baljinnyam B, Raafat A, Rodriguez-Canales J, Strizzi L, Greer YE, Rubin JS, Callahan R.

J Cell Physiol. 2012 May;227(5):1960-71. doi: 10.1002/jcp.22924.


Proliferation and pluripotency of human embryonic stem cells maintained on type I collagen.

Jones MB, Chu CH, Pendleton JC, Betenbaugh MJ, Shiloach J, Baljinnyam B, Rubin JS, Shamblott MJ.

Stem Cells Dev. 2010 Dec;19(12):1923-35. doi: 10.1089/scd.2009.0326. Epub 2010 Oct 12.


Loss-of-function point mutations and two-furin domain derivatives provide insights about R-spondin2 structure and function.

Li SJ, Yen TY, Endo Y, Klauzinska M, Baljinnyam B, Macher B, Callahan R, Rubin JS.

Cell Signal. 2009 Jun;21(6):916-25.


Electron cryomicroscopy reveals different F1+F2 protein States in intact parainfluenza virions.

Ludwig K, Schade B, Böttcher C, Korte T, Ohlwein N, Baljinnyam B, Veit M, Herrmann A.

J Virol. 2008 Apr;82(7):3775-81. doi: 10.1128/JVI.02154-07. Epub 2008 Jan 23.


The 3D structure of the fusion primed Sendai F-protein determined by electron cryomicroscopy.

Ludwig K, Baljinnyam B, Herrmann A, Böttcher C.

EMBO J. 2003 Aug 1;22(15):3761-71.


Lysolipids do not inhibit influenza virus fusion by interaction with hemagglutinin.

Baljinnyam B, Schroth-Diez B, Korte T, Herrmann A.

J Biol Chem. 2002 Jun 7;277(23):20461-7. Epub 2002 Mar 28.


The role of the transmembrane and of the intraviral domain of glycoproteins in membrane fusion of enveloped viruses.

Schroth-Diez B, Ludwig K, Baljinnyam B, Kozerski C, Huang Q, Herrmann A.

Biosci Rep. 2000 Dec;20(6):571-95. Review.


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