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Items: 17

1.

Antituberculosis drugs: reducing efflux=increasing activity.

Rodrigues L, Parish T, Balganesh M, Ainsa JA.

Drug Discov Today. 2017 Mar;22(3):592-599. doi: 10.1016/j.drudis.2017.01.002. Epub 2017 Jan 13. Review.

PMID:
28089787
2.

Design and synthesis of triazolopyrimidine acylsulfonamides as novel anti-mycobacterial leads acting through inhibition of acetohydroxyacid synthase.

Patil V, Kale M, Raichurkar A, Bhaskar B, Prahlad D, Balganesh M, Nandan S, Shahul Hameed P.

Bioorg Med Chem Lett. 2014 May 1;24(9):2222-5. doi: 10.1016/j.bmcl.2014.02.054. Epub 2014 Feb 28.

PMID:
24703230
3.

Bactericidal activity and mechanism of action of AZD5847, a novel oxazolidinone for treatment of tuberculosis.

Balasubramanian V, Solapure S, Iyer H, Ghosh A, Sharma S, Kaur P, Deepthi R, Subbulakshmi V, Ramya V, Ramachandran V, Balganesh M, Wright L, Melnick D, Butler SL, Sambandamurthy VK.

Antimicrob Agents Chemother. 2014;58(1):495-502. doi: 10.1128/AAC.01903-13. Epub 2013 Nov 4.

4.

Optimization of pyrrolamides as mycobacterial GyrB ATPase inhibitors: structure-activity relationship and in vivo efficacy in a mouse model of tuberculosis.

P SH, Solapure S, Mukherjee K, Nandi V, Waterson D, Shandil R, Balganesh M, Sambandamurthy VK, Raichurkar AK, Deshpande A, Ghosh A, Awasthy D, Shanbhag G, Sheikh G, McMiken H, Puttur J, Reddy J, Werngren J, Read J, Kumar M, R M, Chinnapattu M, Madhavapeddi P, Manjrekar P, Basu R, Gaonkar S, Sharma S, Hoffner S, Humnabadkar V, Subbulakshmi V, Panduga V.

Antimicrob Agents Chemother. 2014;58(1):61-70. doi: 10.1128/AAC.01751-13. Epub 2013 Oct 14. Erratum in: Antimicrob Agents Chemother. 2014 Aug;58(8):4993-4.

5.

In vitro and in vivo efficacy of β-lactams against replicating and slowly growing/nonreplicating Mycobacterium tuberculosis.

Solapure S, Dinesh N, Shandil R, Ramachandran V, Sharma S, Bhattacharjee D, Ganguly S, Reddy J, Ahuja V, Panduga V, Parab M, Vishwas KG, Kumar N, Balganesh M, Balasubramanian V.

Antimicrob Agents Chemother. 2013 Jun;57(6):2506-10. doi: 10.1128/AAC.00023-13. Epub 2013 Mar 18.

6.

Involvement of efflux pumps in the resistance to peptidoglycan synthesis inhibitors in Mycobacterium tuberculosis.

Dinesh N, Sharma S, Balganesh M.

Antimicrob Agents Chemother. 2013 Apr;57(4):1941-3. doi: 10.1128/AAC.01957-12. Epub 2013 Jan 18.

7.

Efflux pumps of Mycobacterium tuberculosis play a significant role in antituberculosis activity of potential drug candidates.

Balganesh M, Dinesh N, Sharma S, Kuruppath S, Nair AV, Sharma U.

Antimicrob Agents Chemother. 2012 May;56(5):2643-51. doi: 10.1128/AAC.06003-11. Epub 2012 Feb 6.

8.

Rv1218c, an ABC transporter of Mycobacterium tuberculosis with implications in drug discovery.

Balganesh M, Kuruppath S, Marcel N, Sharma S, Nair A, Sharma U.

Antimicrob Agents Chemother. 2010 Dec;54(12):5167-72. doi: 10.1128/AAC.00610-10. Epub 2010 Oct 4.

9.

Evaluation of killing kinetics of anti-tuberculosis drugs on Mycobacterium tuberculosis using a bacteriophage-based assay.

Marcel N, Nahta A, Balganesh M.

Chemotherapy. 2008;54(5):404-11. doi: 10.1159/000153314. Epub 2008 Sep 5.

PMID:
18772589
10.

Rapid diagnosis of acute pyogenic meningitis by a combined PCR dot-blot assay.

Balganesh M, Lalitha MK, Nathaniel R.

Mol Cell Probes. 2000 Apr;14(2):61-9.

PMID:
10799266
11.

Plasmid-to-chromosome gene transfer in Haemophilus influenza during growth.

Balganesh M, Arrigoni L, Setlow JK.

J Bacteriol. 1986 Oct;168(1):458-9.

12.

Plasmid-to-plasmid recombination in Haemophilus influenzae.

Balganesh M, Setlow JK.

J Bacteriol. 1986 Jan;165(1):308-11.

13.

Genes from plasmid pKM101 in Haemophilus influenzae: separation of functions of mucA and mucB.

Balganesh M, Setlow JK.

Proc Natl Acad Sci U S A. 1985 Nov;82(22):7753-6.

15.

Effect of chromosome homology of plasmid transformation and plasmid conjugal transfer in Haemophilus influenzae.

Balganesh M, Setlow JK.

Basic Life Sci. 1985;30:571-84. No abstract available.

PMID:
2990429
16.
17.

Transfection of Vibrio cholerae by bacteriophage phi 149 DNA.

Balganesh M, Das J.

Biochem Biophys Res Commun. 1979 Oct 12;90(3):726-33. No abstract available.

PMID:
508339

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