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Items: 1 to 50 of 232

1.

Anti-donor MHC Class II Alloantibody Induces Glomerular Injury in Mouse Renal Allografts Subjected to Prolonged Cold Ischemia.

Gorbacheva V, Fan R, Beavers A, Fairchild RL, Baldwin WM 3rd, Valujskikh A.

J Am Soc Nephrol. 2019 Oct 9. pii: ASN.2018111169. doi: 10.1681/ASN.2018111169. [Epub ahead of print]

PMID:
31597715
2.

The neonatal Fc receptor: Key to homeostasic control of IgG and IgG-related biopharmaceuticals.

Baldwin WM 3rd, Valujskikh A, Fairchild RL.

Am J Transplant. 2019 Jul;19(7):1881-1887. doi: 10.1111/ajt.15366. Epub 2019 Apr 15. Review.

PMID:
30903736
3.

IL-27 targets Foxp3+ Tregs to mediate antiinflammatory functions during experimental allergic airway inflammation.

Nguyen QT, Jang E, Le HT, Kim S, Kim D, Dvorina N, Aronica MA, Baldwin WM 3rd, Asosingh K, Comhair S, Min B.

JCI Insight. 2019 Jan 24;4(2). pii: 123216. doi: 10.1172/jci.insight.123216. [Epub ahead of print]

4.

Neutrophil Cathepsin G Regulates Dendritic Cell Production of IL-12 during Development of CD4 T Cell Responses to Antigens in the Skin.

Kish DD, Min S, Dvorina N, Baldwin WM 3rd, Stohlman SA, Fairchild RL.

J Immunol. 2019 Feb 15;202(4):1045-1056. doi: 10.4049/jimmunol.1800841. Epub 2019 Jan 7.

PMID:
30617225
5.

Bronchus-associated lymphoid tissue-resident Foxp3+ T lymphocytes prevent antibody-mediated lung rejection.

Li W, Gauthier JM, Higashikubo R, Hsiao HM, Tanaka S, Vuong L, Ritter JH, Tong AY, Wong BW, Hachem RR, Puri V, Bharat A, Krupnick AS, Hsieh CS, Baldwin WM 3rd, Kelly FL, Palmer SM, Gelman AE, Kreisel D.

J Clin Invest. 2019 Feb 1;129(2):556-568. doi: 10.1172/JCI122083. Epub 2018 Dec 18.

6.

In the absence of natural killer cell activation donor-specific antibody mediates chronic, but not acute, kidney allograft rejection.

Yagisawa T, Tanaka T, Miyairi S, Tanabe K, Dvorina N, Yokoyama WM, Valujskikh A, Baldwin WM 3rd, Fairchild RL.

Kidney Int. 2019 Feb;95(2):350-362. doi: 10.1016/j.kint.2018.08.041. Epub 2018 Nov 29.

PMID:
30503624
7.

Peritransplant VLA-4 blockade inhibits endogenous memory CD8 T cell infiltration into high-risk cardiac allografts and CTLA-4Ig resistant rejection.

Iida S, Miyairi S, Su CA, Abe T, Abe R, Tanabe K, Dvorina N, Baldwin WM 3rd, Fairchild RL.

Am J Transplant. 2019 Apr;19(4):998-1010. doi: 10.1111/ajt.15147. Epub 2018 Nov 26.

PMID:
30372587
8.

Myeloid-derived suppressor cells increase and inhibit donor-reactive T cell responses to graft intestinal epithelium in intestinal transplant patients.

Okano S, Abu-Elmagd K, Kish DD, Keslar K, Baldwin WM 3rd, Fairchild RL, Fujiki M, Khanna A, Osman M, Costa G, Fung J, Miller C, Kayashima H, Hashimoto K.

Am J Transplant. 2018 Oct;18(10):2544-2558. doi: 10.1111/ajt.14718. Epub 2018 Apr 17.

9.

Targeting CD6 for the treatment of experimental autoimmune uveitis.

Zhang L, Li Y, Qiu W, Bell BA, Dvorina N, Baldwin WM 3rd, Singer N, Kern T, Caspi RR, Fox DA, Lin F.

J Autoimmun. 2018 Jun;90:84-93. doi: 10.1016/j.jaut.2018.02.004. Epub 2018 Feb 19.

10.

Shortening the Half-Life of IgG as a Strategy for Decreasing Alloantibodies.

Khedraki R, Baldwin WM 3rd.

Transplantation. 2018 Mar;102(3):342-344. doi: 10.1097/TP.0000000000002091. No abstract available.

PMID:
29461460
11.

Treg-specific IL-27Rα deletion uncovers a key role for IL-27 in Treg function to control autoimmunity.

Do J, Kim D, Kim S, Valentin-Torres A, Dvorina N, Jang E, Nagarajavel V, DeSilva TM, Li X, Ting AH, Vignali DAA, Stohlman SA, Baldwin WM 3rd, Min B.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10190-10195. doi: 10.1073/pnas.1703100114. Epub 2017 Sep 5.

12.

Comparison of normothermic and hypothermic perfusion in porcine kidneys donated after cardiac death.

Blum MF, Liu Q, Soliman B, Dreher P, Okamoto T, Poggio ED, Goldfarb DA, Baldwin WM 3rd, Quintini C.

J Surg Res. 2017 Aug;216:35-45. doi: 10.1016/j.jss.2017.04.008. Epub 2017 Apr 20.

13.

CD4+ T lymphocytes produce adiponectin in response to transplants.

Danturti S, Keslar KS, Steinhoff LR, Fan R, Dvorina N, Valujskikh A, Fairchild RL, Baldwin WM 3rd.

JCI Insight. 2017 Jun 15;2(12). pii: 89641. doi: 10.1172/jci.insight.89641. eCollection 2017 Jun 15.

14.

Complement Dependence of Murine Costimulatory Blockade-Resistant Cellular Cardiac Allograft Rejection.

Chun N, Fairchild RL, Li Y, Liu J, Zhang M, Baldwin WM 3rd, Heeger PS.

Am J Transplant. 2017 Nov;17(11):2810-2819. doi: 10.1111/ajt.14328. Epub 2017 May 30.

15.

Erythropoietin Receptor-Mediated Molecular Crosstalk Promotes T Cell Immunoregulation and Transplant Survival.

Purroy C, Fairchild RL, Tanaka T, Baldwin WM 3rd, Manrique J, Madsen JC, Colvin RB, Alessandrini A, Blazar BR, Fribourg M, Donadei C, Maggiore U, Heeger PS, Cravedi P.

J Am Soc Nephrol. 2017 Aug;28(8):2377-2392. doi: 10.1681/ASN.2016101100. Epub 2017 Mar 16.

16.

Memory CD4 T Cells Induce Antibody-Mediated Rejection of Renal Allografts.

Gorbacheva V, Fan R, Fairchild RL, Baldwin WM 3rd, Valujskikh A.

J Am Soc Nephrol. 2016 Nov;27(11):3299-3307. Epub 2016 Mar 28.

17.

Natural killer cells play a critical role in mediating inflammation and graft failure during antibody-mediated rejection of kidney allografts.

Kohei N, Tanaka T, Tanabe K, Masumori N, Dvorina N, Valujskikh A, Baldwin WM 3rd, Fairchild RL.

Kidney Int. 2016 Jun;89(6):1293-306. doi: 10.1016/j.kint.2016.02.030. Epub 2016 Apr 28.

18.

Strategically Altering the Balance of Macrophage Subpopulations to Inhibit Chronic Rejection.

Baldwin WM 3rd, Morelli AE.

Am J Transplant. 2016 Sep;16(9):2510-1. doi: 10.1111/ajt.13849. Epub 2016 Jun 9. No abstract available.

19.

IL-1 Receptor Signaling on Graft Parenchymal Cells Regulates Memory and De Novo Donor-Reactive CD8 T Cell Responses to Cardiac Allografts.

Iida S, Tsuda H, Tanaka T, Kish DD, Abe T, Su CA, Abe R, Tanabe K, Valujskikh A, Baldwin WM 3rd, Fairchild RL.

J Immunol. 2016 Mar 15;196(6):2827-37. doi: 10.4049/jimmunol.1500876. Epub 2016 Feb 8.

20.

Potential Roles for C1 Inhibitor in Transplantation.

Berger M, Baldwin WM 3rd, Jordan SC.

Transplantation. 2016 Jul;100(7):1415-24. doi: 10.1097/TP.0000000000000995. Review.

PMID:
26599489
21.

Mechanisms of antibody-mediated acute and chronic rejection of kidney allografts.

Baldwin WM 3rd, Valujskikh A, Fairchild RL.

Curr Opin Organ Transplant. 2016 Feb;21(1):7-14. doi: 10.1097/MOT.0000000000000262. Review.

22.

L13a-dependent translational control in macrophages limits the pathogenesis of colitis.

Poddar D, Kaur R, Baldwin WM 3rd, Mazumder B.

Cell Mol Immunol. 2016 Nov;13(6):816-827. doi: 10.1038/cmi.2015.53. Epub 2015 Jul 13.

23.

An IL-27/Lag3 axis enhances Foxp3+ regulatory T cell-suppressive function and therapeutic efficacy.

Do JS, Visperas A, Sanogo YO, Bechtel JJ, Dvorina N, Kim S, Jang E, Stohlman SA, Shen B, Fairchild RL, Baldwin WM III, Vignali DA, Min B.

Mucosal Immunol. 2016 Jan;9(1):137-45. doi: 10.1038/mi.2015.45. Epub 2015 May 27.

24.

Anti-huCD20 antibody therapy for antibody-mediated rejection of renal allografts in a mouse model.

Abe T, Ishii D, Gorbacheva V, Kohei N, Tsuda H, Tanaka T, Dvorina N, Nonomura N, Takahara S, Valujskikh A, Baldwin WM 3rd, Fairchild RL.

Am J Transplant. 2015 May;15(5):1192-204. doi: 10.1111/ajt.13150. Epub 2015 Mar 2.

25.

Acute and chronic rejection: compartmentalization and kinetics of counterbalancing signals in cardiac transplants.

Kaul AM, Goparaju S, Dvorina N, Iida S, Keslar KS, de la Motte CA, Valujskikh A, Fairchild RL, Baldwin WM 3rd.

Am J Transplant. 2015 Feb;15(2):333-45. doi: 10.1111/ajt.13014. Epub 2015 Jan 12.

26.

IFN-γ production by memory helper T cells is required for CD40-independent alloantibody responses.

Gorbacheva V, Fan R, Wang X, Baldwin WM 3rd, Fairchild RL, Valujskikh A.

J Immunol. 2015 Feb 1;194(3):1347-56. doi: 10.4049/jimmunol.1401573. Epub 2014 Dec 29.

27.

B cell activating factor (BAFF) and a proliferation inducing ligand (APRIL) mediate CD40-independent help by memory CD4 T cells.

Gorbacheva V, Ayasoufi K, Fan R, Baldwin WM 3rd, Valujskikh A.

Am J Transplant. 2015 Feb;15(2):346-57. doi: 10.1111/ajt.12984. Epub 2014 Dec 12.

28.

Spontaneous proliferation of H2M-/- CD4 T cells results in unusual acute hepatocellular necrosis.

Do JS, Baldwin WM 3rd, Min B.

PLoS One. 2014 Oct 14;9(10):e110516. doi: 10.1371/journal.pone.0110516. eCollection 2014.

29.

Novel CD8 T cell alloreactivities in CCR5-deficient recipients of class II MHC disparate kidney grafts.

Ishii D, Rosenblum JM, Nozaki T, Schenk AD, Setoguchi K, Su CA, Gorbacheva V, Baldwin WM 3rd, Valujskikh A, Fairchild RL.

J Immunol. 2014 Oct 1;193(7):3816-24. doi: 10.4049/jimmunol.1303256. Epub 2014 Aug 29.

30.

Experimental models of cardiac transplantation: design determines relevance.

Baldwin WM 3rd, Su CA, Shroka TM, Fairchild RL.

Curr Opin Organ Transplant. 2014 Oct;19(5):525-30. doi: 10.1097/MOT.0000000000000113. Review.

31.

Platelets in early antibody-mediated rejection of renal transplants.

Kuo HH, Fan R, Dvorina N, Chiesa-Vottero A, Baldwin WM 3rd.

J Am Soc Nephrol. 2015 Apr;26(4):855-63. doi: 10.1681/ASN.2013121289. Epub 2014 Aug 21.

32.

Graft-derived CCL2 increases graft injury during antibody-mediated rejection of cardiac allografts.

Abe T, Su CA, Iida S, Baldwin WM 3rd, Nonomura N, Takahara S, Fairchild RL.

Am J Transplant. 2014 Aug;14(8):1753-64.

33.

IL-15 induces alloreactive CD28(-) memory CD8 T cell proliferation and CTLA4-Ig resistant memory CD8 T cell activation.

Traitanon O, Gorbachev A, Bechtel JJ, Keslar KS, Baldwin WM 3rd, Poggio ED, Fairchild RL.

Am J Transplant. 2014 Jun;14(6):1277-89. doi: 10.1111/ajt.12719. Epub 2014 May 19.

34.

Cutting edge: IFN-γR signaling in non-T cell targets regulates T cell-mediated intestinal inflammation through multiple mechanisms.

Do JS, Asosingh K, Baldwin WM 3rd, Min B.

J Immunol. 2014 Mar 15;192(6):2537-41. doi: 10.4049/jimmunol.1303101. Epub 2014 Feb 12.

35.

Ribosomal protein L13a deficiency in macrophages promotes atherosclerosis by limiting translation control-dependent retardation of inflammation.

Basu A, Poddar D, Robinet P, Smith JD, Febbraio M, Baldwin WM 3rd, Mazumder B.

Arterioscler Thromb Vasc Biol. 2014 Mar;34(3):533-42. doi: 10.1161/ATVBAHA.113.302573. Epub 2014 Jan 16.

36.

A platelet-inspired paradigm for nanomedicine targeted to multiple diseases.

Modery-Pawlowski CL, Kuo HH, Baldwin WM, Sen Gupta A.

Nanomedicine (Lond). 2013 Oct;8(10):1709-27. doi: 10.2217/nnm.13.113. Review.

PMID:
24074391
37.

Endogenous memory CD8 T cells are activated within cardiac allografts without mediating rejection.

Setoguchi K, Hattori Y, Iida S, Baldwin WM 3rd, Fairchild RL.

Am J Transplant. 2013 Sep;13(9):2293-307. doi: 10.1111/ajt.12372. Epub 2013 Aug 5.

38.

Absence of FcγRIII results in increased proinflammatory response in FcγRIII-KO cardiac recipients.

Erdinc Sunay MM, Fox-Talbot K, Velidedeoglu E, Baldwin WM 3rd, Wasowska BA.

Transplantation. 2013 Oct 15;96(7):601-8. doi: 10.1097/TP.0b013e31829c2455.

39.

Stat3β mitigates development of atherosclerosis in apolipoprotein E-deficient mice.

Lee J, Baldwin WM 3rd, Lee CY, Desiderio S.

J Mol Med (Berl). 2013 Aug;91(8):965-76. doi: 10.1007/s00109-013-1013-5. Epub 2013 Apr 26.

40.

An extraribosomal function of ribosomal protein L13a in macrophages resolves inflammation.

Poddar D, Basu A, Baldwin WM 3rd, Kondratov RV, Barik S, Mazumder B.

J Immunol. 2013 Apr 1;190(7):3600-12. doi: 10.4049/jimmunol.1201933. Epub 2013 Mar 4.

41.

Alloantibody induced platelet responses in transplants: potent mediators in small packages.

Kuo HH, Morrell CN, Baldwin WM 3rd.

Hum Immunol. 2012 Dec;73(12):1233-8. doi: 10.1016/j.humimm.2012.06.011. Epub 2012 Jul 10. Review.

42.

Platelets present antigen in the context of MHC class I.

Chapman LM, Aggrey AA, Field DJ, Srivastava K, Ture S, Yui K, Topham DJ, Baldwin WM 3rd, Morrell CN.

J Immunol. 2012 Jul 15;189(2):916-23. doi: 10.4049/jimmunol.1200580. Epub 2012 Jun 15.

43.

Antibody-mediated rejection of single class I MHC-disparate cardiac allografts.

Hattori Y, Bucy RP, Kubota Y, Baldwin WM 3rd, Fairchild RL.

Am J Transplant. 2012 Aug;12(8):2017-28. doi: 10.1111/j.1600-6143.2012.04073.x. Epub 2012 May 11.

44.

The spleen is the major source of antidonor antibody-secreting cells in murine heart allograft recipients.

Sicard A, Phares TW, Yu H, Fan R, Baldwin WM 3rd, Fairchild RL, Valujskikh A.

Am J Transplant. 2012 Jul;12(7):1708-19. doi: 10.1111/j.1600-6143.2012.04009.x. Epub 2012 Mar 15.

45.

Absence of mannose-binding lectin prevents hyperglycemic cardiovascular complications.

Pavlov VI, La Bonte LR, Baldwin WM, Markiewski MM, Lambris JD, Stahl GL.

Am J Pathol. 2012 Jan;180(1):104-12. doi: 10.1016/j.ajpath.2011.09.026. Epub 2011 Nov 8.

46.

NK cells: new partners in antibody-triggered chronic rejection.

Li XC, Baldwin WM 3rd.

Am J Transplant. 2012 Feb;12(2):275-6. doi: 10.1111/j.1600-6143.2011.03839.x. Epub 2011 Nov 9. No abstract available.

47.

Of mice and men: terminal complement inhibition with anti-C5 monoclonal antibodies.

Woodle ES, Baldwin WM 3rd.

Am J Transplant. 2011 Nov;11(11):2277-8. doi: 10.1111/j.1600-6143.2011.03760.x. No abstract available.

48.

B cells in cardiac transplants: from clinical questions to experimental models.

Baldwin WM 3rd, Halushka MK, Valujskikh A, Fairchild RL.

Semin Immunol. 2012 Apr;24(2):122-30. doi: 10.1016/j.smim.2011.08.017. Epub 2011 Sep 19. Review.

49.

A TLR5 agonist inhibits acute renal ischemic failure.

Fukuzawa N, Petro M, Baldwin WM 3rd, Gudkov AV, Fairchild RL.

J Immunol. 2011 Oct 1;187(7):3831-9. doi: 10.4049/jimmunol.1003238. Epub 2011 Sep 2.

50.

Antibody-mediated rejection--an ounce of prevention is worth a pound of cure.

Bradley JA, Baldwin WM, Bingaman A, Ellenrieder C, Gebel HM, Glotz D, Kirk AD.

Am J Transplant. 2011 Jun;11(6):1131-9. doi: 10.1111/j.1600-6143.2011.03581.x.

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