Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 189


PRMT7 methylates eukaryotic translation initiation factor 2α and regulates its role in stress granule formation.

Haghandish N, Baldwin RM, Morettin A, Dawit HT, Adhikary H, Masson JY, Mazroui R, Trinkle-Mulcahy L, Côté J.

Mol Biol Cell. 2019 Mar 15;30(6):778-793. doi: 10.1091/mbc.E18-05-0330. Epub 2019 Jan 30.


Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy.

Guo H, Chitiprolu M, Roncevic L, Javalet C, Hemming FJ, Trung MT, Meng L, Latreille E, Tanese de Souza C, McCulloch D, Baldwin RM, Auer R, Côté J, Russell RC, Sadoul R, Gibbings D.

Dev Cell. 2017 Dec 18;43(6):716-730.e7. doi: 10.1016/j.devcel.2017.11.018.


RNA binding protein RALY promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells.

Bondy-Chorney E, Baldwin RM, Didillon A, Chabot B, Jasmin BJ, Côté J.

Int J Biochem Cell Biol. 2017 Oct;91(Pt B):124-135. doi: 10.1016/j.biocel.2017.07.008. Epub 2017 Jul 19.


Tudor Domain Containing Protein 3 Promotes Tumorigenesis and Invasive Capacity of Breast Cancer Cells.

Morettin A, Paris G, Bouzid Y, Baldwin RM, Falls TJ, Bell JC, Côté J.

Sci Rep. 2017 Jul 11;7(1):5153. doi: 10.1038/s41598-017-04955-4.


ABC transporter polymorphisms are associated with irinotecan pharmacokinetics and neutropenia.

Li M, Seiser EL, Baldwin RM, Ramirez J, Ratain MJ, Innocenti F, Kroetz DL.

Pharmacogenomics J. 2018 Jan;18(1):35-42. doi: 10.1038/tpj.2016.75. Epub 2016 Nov 15.


Synthesis and in vivo Evaluation of Fluorine-18 and Iodine-123 Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine Derivatives as PET and SPECT Radiotracers for Mapping A2A Receptors.

Vala C, Morley TJ, Zhang X, Papin C, Tavares AA, Lee HS, Constantinescu C, Barret O, Carroll VM, Baldwin RM, Tamagnan GD, Alagille D.

ChemMedChem. 2016 Sep 6;11(17):1936-43. doi: 10.1002/cmdc.201600219. Epub 2016 Jul 13.


Identification and in vivo evaluation of a fluorine-18 rolipram analogue, [(18) F]MNI-617, as a radioligand for PDE4 imaging in mammalian brain.

Thomae D, Morley TJ, Lee HS, Barret O, Constantinescu C, Papin C, Baldwin RM, Tamagnan GD, Alagille D.

J Labelled Comp Radiopharm. 2016 May 15;59(5):205-13. doi: 10.1002/jlcr.3389. Epub 2016 Mar 22.


Identification of the PRMT1v1 and PRMT1v2 specific interactomes by quantitative mass spectrometry in breast cancer cells.

Baldwin RM, Bejide M, Trinkle-Mulcahy L, Côté J.

Proteomics. 2015 Jul;15(13):2187-97. doi: 10.1002/pmic.201400209. Epub 2015 Mar 19.


Arginine methyltransferases as novel therapeutic targets for breast cancer.

Morettin A, Baldwin RM, Côté J.

Mutagenesis. 2015 Mar;30(2):177-89. doi: 10.1093/mutage/geu039. Review.


Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression.

Baldwin RM, Haghandish N, Daneshmand M, Amin S, Paris G, Falls TJ, Bell JC, Islam S, Côté J.

Oncotarget. 2015 Feb 20;6(5):3013-32.


Automated one-step radiosynthesis of the CB1 receptor imaging agent [(18) F]MK-9470.

Thomae D, Morley TJ, Hamill T, Carroll VM, Papin C, Twardy NM, Lee HS, Hargreaves R, Baldwin RM, Tamagnan G, Alagille D.

J Labelled Comp Radiopharm. 2014 Aug;57(10):611-4. doi: 10.1002/jlcr.3219. Epub 2014 Aug 25.


Role of PRMTs in cancer: Could minor isoforms be leaving a mark?

Baldwin RM, Morettin A, Côté J.

World J Biol Chem. 2014 May 26;5(2):115-29. doi: 10.4331/wjbc.v5.i2.115. Review.


Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance).

Chhibber A, Mefford J, Stahl EA, Pendergrass SA, Baldwin RM, Owzar K, Li M, Winer EP, Hudis CA, Zembutsu H, Kubo M, Nakamura Y, McLeod HL, Ratain MJ, Shulman LN, Ritchie MD, Plenge RM, Witte JS, Kroetz DL.

Pharmacogenomics J. 2014 Aug;14(4):336-42. doi: 10.1038/tpj.2014.2. Epub 2014 Feb 11.


Chemical characterization and hydrothermal pretreatment of Salicornia bigelovii straw for enhanced enzymatic hydrolysis and bioethanol potential.

Cybulska I, Chaturvedi T, Brudecki GP, Kádár Z, Meyer AS, Baldwin RM, Thomsen MH.

Bioresour Technol. 2014 Feb;153:165-72. doi: 10.1016/j.biortech.2013.11.071. Epub 2013 Dec 1.


Synthesis and biological evaluation of positron emission tomography radiotracers targeting serotonin 4 receptors in brain: [18F]MNI-698 and [18F]MNI-699.

Caillé F, Morley TJ, Tavares AA, Papin C, Twardy NM, Alagille D, Lee HS, Baldwin RM, Seibyl JP, Barret O, Tamagnan GD.

Bioorg Med Chem Lett. 2013 Dec 1;23(23):6243-7. doi: 10.1016/j.bmcl.2013.09.097. Epub 2013 Oct 9.


Kinetic modeling, test-retest, and dosimetry of 123I-MNI-420 in humans.

Tavares AA, Batis JC, Papin C, Jennings D, Alagille D, Russell DS, Vala C, Lee H, Baldwin RM, Zubal IG, Marek KL, Seibyl JP, Barret O, Tamagnan GD.

J Nucl Med. 2013 Oct;54(10):1760-7. doi: 10.2967/jnumed.113.119933. Epub 2013 Aug 22.


A thalamocorticostriatal dopamine network for psychostimulant-enhanced human cognitive flexibility.

Samanez-Larkin GR, Buckholtz JW, Cowan RL, Woodward ND, Li R, Ansari MS, Arrington CM, Baldwin RM, Smith CE, Treadway MT, Kessler RM, Zald DH.

Biol Psychiatry. 2013 Jul 15;74(2):99-105. doi: 10.1016/j.biopsych.2012.10.032. Epub 2012 Dec 27.


Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.

Wheeler HE, Gamazon ER, Wing C, Njiaju UO, Njoku C, Baldwin RM, Owzar K, Jiang C, Watson D, Shterev I, Kubo M, Zembutsu H, Winer EP, Hudis CA, Shulman LN, Nakamura Y, Ratain MJ, Kroetz DL; Cancer and Leukemia Group B, Cox NJ, Dolan ME.

Clin Cancer Res. 2013 Jan 15;19(2):491-9. doi: 10.1158/1078-0432.CCR-12-2618. Epub 2012 Nov 30.


Alternatively spliced protein arginine methyltransferase 1 isoform PRMT1v2 promotes the survival and invasiveness of breast cancer cells.

Baldwin RM, Morettin A, Paris G, Goulet I, Côté J.

Cell Cycle. 2012 Dec 15;11(24):4597-612. doi: 10.4161/cc.22871. Epub 2012 Nov 27.


A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.

Baldwin RM, Owzar K, Zembutsu H, Chhibber A, Kubo M, Jiang C, Watson D, Eclov RJ, Mefford J, McLeod HL, Friedman PN, Hudis CA, Winer EP, Jorgenson EM, Witte JS, Shulman LN, Nakamura Y, Ratain MJ, Kroetz DL.

Clin Cancer Res. 2012 Sep 15;18(18):5099-109. Epub 2012 Jul 27.


Functional characterization of ABCC2 promoter polymorphisms and allele-specific expression.

Nguyen TD, Markova S, Liu W, Gow JM, Baldwin RM, Habashian M, Relling MV, Ratain MJ, Kroetz DL.

Pharmacogenomics J. 2013 Oct;13(5):396-402. doi: 10.1038/tpj.2012.20. Epub 2012 Jun 5.


Dopaminergic mechanisms of individual differences in human effort-based decision-making.

Treadway MT, Buckholtz JW, Cowan RL, Woodward ND, Li R, Ansari MS, Baldwin RM, Schwartzman AN, Kessler RM, Zald DH.

J Neurosci. 2012 May 2;32(18):6170-6. doi: 10.1523/JNEUROSCI.6459-11.2012.


The metabotropic glutamate receptor 8 agonist (S)-3,4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease.

Johnson KA, Jones CK, Tantawy MN, Bubser M, Marvanova M, Ansari MS, Baldwin RM, Conn PJ, Niswender CM.

Neuropharmacology. 2013 Mar;66:187-95. doi: 10.1016/j.neuropharm.2012.03.029. Epub 2012 Apr 21.


Evidence for chronically altered serotonin function in the cerebral cortex of female 3,4-methylenedioxymethamphetamine polydrug users.

Di Iorio CR, Watkins TJ, Dietrich MS, Cao A, Blackford JU, Rogers B, Ansari MS, Baldwin RM, Li R, Kessler RM, Salomon RM, Benningfield M, Cowan RL.

Arch Gen Psychiatry. 2012 Apr;69(4):399-409. doi: 10.1001/archgenpsychiatry.2011.156. Epub 2011 Dec 5.


Multimodal image coregistration and inducible selective cell ablation to evaluate imaging ligands.

Virostko J, Henske J, Vinet L, Lamprianou S, Dai C, Radhika A, Baldwin RM, Ansari MS, Hefti F, Skovronsky D, Kung HF, Herrera PL, Peterson TE, Meda P, Powers AC.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20719-24. doi: 10.1073/pnas.1109480108. Epub 2011 Dec 5.


Omeprazole limited sampling strategies to predict area under the concentration-time curve ratios: implications for cytochrome P450 2C19 and 3A phenotyping.

Lawson EB, Wu JC, Baldwin RM, Ingelman-Sundberg M, Rosenborg S, Yim DS, Yin OQ, Capparelli EV, Ma JD.

Eur J Clin Pharmacol. 2012 Apr;68(4):407-13. doi: 10.1007/s00228-011-1136-y. Epub 2011 Oct 19.


Impact of isoflurane anesthesia on D2 receptor occupancy by [18F]fallypride measured by microPET with a modified Logan plot.

Tantawy MN, Peterson TE, Jones CK, Johnson K, Rook JM, Conn PJ, Baldwin RM, Ansari MS, Kessler RM.

Synapse. 2011 Nov;65(11):1173-80. doi: 10.1002/syn.20955. Epub 2011 Jun 17.


Potent mGluR5 antagonists: pyridyl and thiazolyl-ethynyl-3,5-disubstituted-phenyl series.

Alagille D, DaCosta H, Chen Y, Hemstapat K, Rodriguez A, Baldwin RM, Conn PJ, Tamagnan GD.

Bioorg Med Chem Lett. 2011 Jun 1;21(11):3243-7. doi: 10.1016/j.bmcl.2011.04.047. Epub 2011 Apr 20. Erratum in: Bioorg Med Chem Lett. 2012 Mar 1;22(5):2130. Conn, Jeffrey P [corrected to Conn, P Jeffrey].


2-Arylimidazo[2,1-b]benzothiazoles: a new family of amyloid binding agents with potential for PET and SPECT imaging of Alzheimer's brain.

Alagille D, DaCosta H, Baldwin RM, Tamagnan GD.

Bioorg Med Chem Lett. 2011 May 15;21(10):2966-8. doi: 10.1016/j.bmcl.2011.03.052. Epub 2011 Mar 21.


Correlation of individual differences in schizotypal personality traits with amphetamine-induced dopamine release in striatal and extrastriatal brain regions.

Woodward ND, Cowan RL, Park S, Ansari MS, Baldwin RM, Li R, Doop M, Kessler RM, Zald DH.

Am J Psychiatry. 2011 Apr;168(4):418-26. doi: 10.1176/appi.ajp.2010.10020165. Epub 2010 Dec 15.


Quantitative, preclinical PET of translocator protein expression in glioma using 18F-N-fluoroacetyl-N-(2,5-dimethoxybenzyl)-2-phenoxyaniline.

Buck JR, McKinley ET, Hight MR, Fu A, Tang D, Smith RA, Tantawy MN, Peterson TE, Colvin D, Ansari MS, Baldwin RM, Zhao P, Guleryuz S, Manning HC.

J Nucl Med. 2011 Jan;52(1):107-14. doi: 10.2967/jnumed.110.081703. Epub 2010 Dec 13.


Dopamine and serotonin transporter availability in chronic heroin users: a [¹²³I]β-CIT SPECT imaging study.

Cosgrove KP, Tellez-Jacques K, Pittman B, Petrakis I, Baldwin RM, Tamagnan G, Seibyl J, Kosten T, Staley JK.

Psychiatry Res. 2010 Dec 30;184(3):192-5. doi: 10.1016/j.pscychresns.2010.08.001. Epub 2010 Nov 3.


Coordination of glioblastoma cell motility by PKCι.

Baldwin RM, Barrett GM, Parolin DA, Gillies JK, Paget JA, Lavictoire SJ, Gray DA, Lorimer IA.

Mol Cancer. 2010 Sep 3;9:233. doi: 10.1186/1476-4598-9-233.


Dopaminergic network differences in human impulsivity.

Buckholtz JW, Treadway MT, Cowan RL, Woodward ND, Li R, Ansari MS, Baldwin RM, Schwartzman AN, Shelby ES, Smith CE, Kessler RM, Zald DH.

Science. 2010 Jul 30;329(5991):532. doi: 10.1126/science.1185778.


SPECT imaging with the serotonin transporter radiotracer [123I]p ZIENT in nonhuman primate brain.

Cosgrove KP, Staley JK, Baldwin RM, Bois F, Plisson C, Al-Tikriti MS, Seibyl JP, Goodman MM, Tamagnan GD.

Nucl Med Biol. 2010 Jul;37(5):587-91. doi: 10.1016/j.nucmedbio.2010.03.007. Epub 2010 May 6.


A novel in vitro assay to assess phosphorylation of 3'-[(18)F]fluoro-3'-deoxythymidine.

Guo N, Xie J, Manning HC, Deane NG, Ansari MS, Coffey RJ, Gore J, Price RR, Baldwin RM, McIntyre JO.

Mol Imaging Biol. 2011 Apr;13(2):257-64. doi: 10.1007/s11307-010-0351-8.


Mesolimbic dopamine reward system hypersensitivity in individuals with psychopathic traits.

Buckholtz JW, Treadway MT, Cowan RL, Woodward ND, Benning SD, Li R, Ansari MS, Baldwin RM, Schwartzman AN, Shelby ES, Smith CE, Cole D, Kessler RM, Zald DH.

Nat Neurosci. 2010 Apr;13(4):419-21. doi: 10.1038/nn.2510. Epub 2010 Mar 14.


The interrelationship of dopamine D2-like receptor availability in striatal and extrastriatal brain regions in healthy humans: a principal component analysis of [18F]fallypride binding.

Zald DH, Woodward ND, Cowan RL, Riccardi P, Ansari MS, Baldwin RM, Cowan RL, Smith CE, Hakyemez H, Li R, Kessler RM.

Neuroimage. 2010 May 15;51(1):53-62. doi: 10.1016/j.neuroimage.2010.02.006. Epub 2010 Feb 10.


[(18)F]Fallypride dopamine D2 receptor studies using delayed microPET scans and a modified Logan plot.

Tantawy MN, Jones CK, Baldwin RM, Ansari MS, Conn PJ, Kessler RM, Peterson TE.

Nucl Med Biol. 2009 Nov;36(8):931-40. doi: 10.1016/j.nucmedbio.2009.06.007. Epub 2009 Oct 3.


Regional distribution and behavioral correlates of 5-HT(2A) receptors in Alzheimer's disease with [(18)F]deuteroaltanserin and PET.

Santhosh L, Estok KM, Vogel RS, Tamagnan GD, Baldwin RM, Mitsis EM, Macavoy MG, Staley JK, van Dyck CH.

Psychiatry Res. 2009 Sep 30;173(3):212-7. doi: 10.1016/j.pscychresns.2009.03.007. Epub 2009 Aug 13.


Imaging biomarkers predict response to anti-HER2 (ErbB2) therapy in preclinical models of breast cancer.

Shah C, Miller TW, Wyatt SK, McKinley ET, Olivares MG, Sanchez V, Nolting DD, Buck JR, Zhao P, Ansari MS, Baldwin RM, Gore JC, Schiff R, Arteaga CL, Manning HC.

Clin Cancer Res. 2009 Jul 15;15(14):4712-21. doi: 10.1158/1078-0432.CCR-08-2635. Epub 2009 Jul 7.


Toxicity and metabolism of methylnaphthalenes: comparison with naphthalene and 1-nitronaphthalene.

Lin CY, Wheelock AM, Morin D, Baldwin RM, Lee MG, Taff A, Plopper C, Buckpitt A, Rohde A.

Toxicology. 2009 Jun 16;260(1-3):16-27. doi: 10.1016/j.tox.2009.03.002. Epub 2009 Mar 18. Review.


Cerebral morphology and dopamine D2/D3 receptor distribution in humans: a combined [18F]fallypride and voxel-based morphometry study.

Woodward ND, Zald DH, Ding Z, Riccardi P, Ansari MS, Baldwin RM, Cowan RL, Li R, Kessler RM.

Neuroimage. 2009 May 15;46(1):31-8. doi: 10.1016/j.neuroimage.2009.01.049. Epub 2009 Feb 5. Erratum in: Neuroimage. 2009 Oct 1;47(4):2090.


Dopamine and serotonin transporter availability during acute alcohol withdrawal: effects of comorbid tobacco smoking.

Cosgrove KP, Krantzler E, Frohlich EB, Stiklus S, Pittman B, Tamagnan GD, Baldwin RM, Bois F, Seibyl JP, Krystal JH, O'Malley SS, Staley JK.

Neuropsychopharmacology. 2009 Sep;34(10):2218-26. doi: 10.1038/npp.2009.49. Epub 2009 May 13.


Regulation of human CYP2C18 and CYP2C19 in transgenic mice: influence of castration, testosterone, and growth hormone.

Löfgren S, Baldwin RM, Carlerös M, Terelius Y, Fransson-Steen R, Mwinyi J, Waxman DJ, Ingelman-Sundberg M.

Drug Metab Dispos. 2009 Jul;37(7):1505-12. doi: 10.1124/dmd.109.026963. Epub 2009 Apr 1.


Midbrain dopamine receptor availability is inversely associated with novelty-seeking traits in humans.

Zald DH, Cowan RL, Riccardi P, Baldwin RM, Ansari MS, Li R, Shelby ES, Smith CE, McHugo M, Kessler RM.

J Neurosci. 2008 Dec 31;28(53):14372-8. doi: 10.1523/JNEUROSCI.2423-08.2008.


Synthesis of 5- and 6-substituted 2-(4-dimethylaminophenyl)-1,3-benzoxazoles and their in vitro and in vivo evaluation as imaging agents for amyloid plaque.

Hausner SH, Alagille D, Koren AO, Amici L, Staley JK, Cosgrove KP, Baldwin RM, Tamagnan GD.

Bioorg Med Chem Lett. 2009 Jan 15;19(2):543-5. doi: 10.1016/j.bmcl.2008.05.033. Epub 2008 May 15.


Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer.

Manning HC, Merchant NB, Foutch AC, Virostko JM, Wyatt SK, Shah C, McKinley ET, Xie J, Mutic NJ, Washington MK, LaFleur B, Tantawy MN, Peterson TE, Ansari MS, Baldwin RM, Rothenberg ML, Bornhop DJ, Gore JC, Coffey RJ.

Clin Cancer Res. 2008 Nov 15;14(22):7413-22. doi: 10.1158/1078-0432.CCR-08-0239.


Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats.

Jones CK, Brady AE, Davis AA, Xiang Z, Bubser M, Tantawy MN, Kane AS, Bridges TM, Kennedy JP, Bradley SR, Peterson TE, Ansari MS, Baldwin RM, Kessler RM, Deutch AY, Lah JJ, Levey AI, Lindsley CW, Conn PJ.

J Neurosci. 2008 Oct 8;28(41):10422-33. doi: 10.1523/JNEUROSCI.1850-08.2008.


Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects.

Ohlsson Rosenborg S, Mwinyi J, Andersson M, Baldwin RM, Pedersen RS, Sim SC, Bertilsson L, Ingelman-Sundberg M, Eliasson E.

Eur J Clin Pharmacol. 2008 Dec;64(12):1175-9. doi: 10.1007/s00228-008-0529-z. Epub 2008 Jul 25.


Supplemental Content

Loading ...
Support Center