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Items: 1 to 50 of 122

1.

Rationale and design of the STeroids to REduce Systemic inflammation after infant heart Surgery (STRESS) trial.

Hill KD, Baldwin HS, Bichel DP, Butts RJ, Chamberlain RC, Ellis AM, Graham EM, Hickerson J, Hornik CP, Jacobs JP, Jacobs ML, Jaquiss RD, Kannankeril PJ, O'Brien SM, Torok R, Turek JW, Li JS; STRESS Network Investigators.

Am Heart J. 2019 Dec 9;220:192-202. doi: 10.1016/j.ahj.2019.11.016. [Epub ahead of print]

PMID:
31855716
2.

Loss of flow responsive Tie1 results in Impaired
Aortic valve remodeling.

Qu X, Violette K, Sewell-Loftin MK, Soslow J, Saint-Jean L, Hinton RB, Merryman WD, Baldwin HS.

Dev Biol. 2019 Nov 1;455(1):73-84. doi: 10.1016/j.ydbio.2019.07.011. Epub 2019 Jul 15.

PMID:
31319059
3.

Tie2 regulates endocardial sprouting and myocardial trabeculation.

Qu X, Harmelink C, Baldwin HS.

JCI Insight. 2019 May 21;5. pii: 96002. doi: 10.1172/jci.insight.96002.

4.

Myocardial differentiation is dependent upon endocardial signaling during early cardiogenesis in vitro.

Saint-Jean L, Barkas N, Harmelink C, Tompkins KL, Oakey RJ, Baldwin HS.

Development. 2019 May 8;146(9). pii: dev172619. doi: 10.1242/dev.172619.

5.

Erratum to: Etiology and Morphogenesis of Congenital Heart Disease.

Nakanishi T, Markwald RR, Baldwin HS, Keller BB, Srivastava D, Yamagishi H.

In: Nakanishi T, Markwald RR, Baldwin HS, Keller BB, Srivastava D, Yamagishi H, editors. Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology [Internet]. Tokyo: Springer; 2016. No abstract available.
2018 Apr 4.

6.

A Novel Role for Endocardium in Perinatal Valve Development: Lessons Learned from Tissue-Specific Gene Deletion of the Tie1 Receptor Tyrosine Kinase.

Qu X, Baldwin HS.

In: Nakanishi T, Markwald RR, Baldwin HS, Keller BB, Srivastava D, Yamagishi H, editors. Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology [Internet]. Tokyo: Springer; 2016. Chapter 19.
2016 Jun 25.

7.

Lymphangiogenesis in Chronic Rejection and Coronary Allograft Vasculopathy: An Emerging Diagnostic and Therapeutic Target?

Baldwin HS, Drakos SG.

Circulation. 2018 Jan 30;137(5):504-507. doi: 10.1161/CIRCULATIONAHA.117.031716. No abstract available.

PMID:
29378756
8.

Endothelial Tie1-mediated angiogenesis and vascular abnormalization promote tumor progression and metastasis.

La Porta S, Roth L, Singhal M, Mogler C, Spegg C, Schieb B, Qu X, Adams RH, Baldwin HS, Savant S, Augustin HG.

J Clin Invest. 2018 Feb 1;128(2):834-845. doi: 10.1172/JCI94674. Epub 2018 Jan 22.

9.

Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease.

Angel PM, Narmoneva DA, Sewell-Loftin MK, Munjal C, Dupuis L, Landis BJ, Jegga A, Kern CB, Merryman WD, Baldwin HS, Bressan GM, Hinton RB.

Ann Biomed Eng. 2017 Nov;45(11):2548-2562. doi: 10.1007/s10439-017-1899-0. Epub 2017 Aug 15.

10.

Advances in MALDI imaging mass spectrometry of proteins in cardiac tissue, including the heart valve.

Angel PM, Baldwin HS, Gottlieb Sen D, Su YR, Mayer JE, Bichell D, Drake RR.

Biochim Biophys Acta Proteins Proteom. 2017 Jul;1865(7):927-935. doi: 10.1016/j.bbapap.2017.03.009. Epub 2017 Mar 21. Review.

11.

Alterations in sarcomere function modify the hyperplastic to hypertrophic transition phase of mammalian cardiomyocyte development.

Nixon BR, Williams AF, Glennon MS, de Feria AE, Sebag SC, Baldwin HS, Becker JR.

JCI Insight. 2017 Feb 23;2(4):e90656. doi: 10.1172/jci.insight.90656.

12.

Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFβR3 In Vitro.

DeLaughter DM, Clark CR, Christodoulou DC, Seidman CE, Baldwin HS, Seidman JG, Barnett JV.

PLoS One. 2016 Aug 9;11(8):e0159710. doi: 10.1371/journal.pone.0159710. eCollection 2016.

13.

Making a heart: advances in understanding the mechanisms of cardiac development.

Dees E, Baldwin HS.

Curr Opin Pediatr. 2016 Oct;28(5):584-9. doi: 10.1097/MOP.0000000000000401. Review.

14.

Feasibility of a Team Approach to Complex Congenital Heart Defect Neurodevelopmental Follow-Up: Early Experience of a Combined Cardiology/Neonatal Intensive Care Unit Follow-Up Program.

Chorna O, Baldwin HS, Neumaier J, Gogliotti S, Powers D, Mouvery A, Bichell D, Maitre NL.

Circ Cardiovasc Qual Outcomes. 2016 Jul;9(4):432-40. doi: 10.1161/CIRCOUTCOMES.116.002614. Epub 2016 May 24.

15.

Postnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice.

Qu X, Li J, Baldwin HS.

Biochem Biophys Res Commun. 2016 Feb 12;470(3):613-619. doi: 10.1016/j.bbrc.2016.01.096. Epub 2016 Jan 19.

16.

The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk Cells.

Savant S, La Porta S, Budnik A, Busch K, Hu J, Tisch N, Korn C, Valls AF, Benest AV, Terhardt D, Qu X, Adams RH, Baldwin HS, Ruiz de Almodóvar C, Rodewald HR, Augustin HG.

Cell Rep. 2015 Sep 22;12(11):1761-73. doi: 10.1016/j.celrep.2015.08.024. Epub 2015 Sep 3.

17.

Notch1 Mutation Leads to Valvular Calcification Through Enhanced Myofibroblast Mechanotransduction.

Chen J, Ryzhova LM, Sewell-Loftin MK, Brown CB, Huppert SS, Baldwin HS, Merryman WD.

Arterioscler Thromb Vasc Biol. 2015 Jul;35(7):1597-605. doi: 10.1161/ATVBAHA.114.305095. Epub 2015 May 28.

18.

Myocardial contraction and hyaluronic acid mechanotransduction in epithelial-to-mesenchymal transformation of endocardial cells.

Sewell-Loftin MK, DeLaughter DM, Peacock JR, Brown CB, Baldwin HS, Barnett JV, Merryman WD.

Biomaterials. 2014 Mar;35(9):2809-15. doi: 10.1016/j.biomaterials.2013.12.051. Epub 2014 Jan 14.

19.

Bves and NDRG4 regulate directional epicardial cell migration through autocrine extracellular matrix deposition.

Benesh EC, Miller PM, Pfaltzgraff ER, Grega-Larson NE, Hager HA, Sung BH, Qu X, Baldwin HS, Weaver AM, Bader DM.

Mol Biol Cell. 2013 Nov;24(22):3496-510. doi: 10.1091/mbc.E12-07-0539. Epub 2013 Sep 18.

20.

Cdc42 promotes host defenses against fatal infection.

Lee K, Boyd KL, Parekh DV, Kehl-Fie TE, Baldwin HS, Brakebusch C, Skaar EP, Boothby M, Zent R.

Infect Immun. 2013 Aug;81(8):2714-23. doi: 10.1128/IAI.01114-12. Epub 2013 May 20.

21.

Nfatc1 directs the endocardial progenitor cells to make heart valve primordium.

Wu B, Baldwin HS, Zhou B.

Trends Cardiovasc Med. 2013 Nov;23(8):294-300. doi: 10.1016/j.tcm.2013.04.003. Epub 2013 May 10. Review.

22.

Spatial transcriptional profile of the chick and mouse endocardial cushions identify novel regulators of endocardial EMT in vitro.

DeLaughter DM, Christodoulou DC, Robinson JY, Seidman CE, Baldwin HS, Seidman JG, Barnett JV.

J Mol Cell Cardiol. 2013 Jun;59:196-204. doi: 10.1016/j.yjmcc.2013.03.016. Epub 2013 Apr 1.

23.

Cimetidine-associated patent ductus arteriosus is mediated via a cytochrome P450 mechanism independent of H2 receptor antagonism.

Cotton RB, Shah LP, Poole SD, Ehinger NJ, Brown N, Shelton EL, Slaughter JC, Baldwin HS, Paria BC, Reese J.

J Mol Cell Cardiol. 2013 Jun;59:86-94. doi: 10.1016/j.yjmcc.2013.02.010. Epub 2013 Feb 27.

24.

Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling.

Wu B, Zhang Z, Lui W, Chen X, Wang Y, Chamberlain AA, Moreno-Rodriguez RA, Markwald RR, O'Rourke BP, Sharp DJ, Zheng D, Lenz J, Baldwin HS, Chang CP, Zhou B.

Cell. 2012 Nov 21;151(5):1083-96. doi: 10.1016/j.cell.2012.10.023.

25.

A novel technique for quantifying mouse heart valve leaflet stiffness with atomic force microscopy.

Sewell-Loftin MK, Brown CB, Baldwin HS, Merryman WD.

J Heart Valve Dis. 2012 Jul;21(4):513-20.

26.

Pediatric cardiology: moving into a new era of diagnosis and therapeutic intervention.

Baldwin HS.

Curr Opin Pediatr. 2012 Oct;24(5):555-6. doi: 10.1097/MOP.0b013e328357b276. No abstract available.

PMID:
22935757
27.

Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis.

Vijayaraj P, Le Bras A, Mitchell N, Kondo M, Juliao S, Wasserman M, Beeler D, Spokes K, Aird WC, Baldwin HS, Oettgen P.

Development. 2012 Nov;139(21):3973-85. doi: 10.1242/dev.081596. Epub 2012 Aug 29.

28.

Role of Tie1 in shear stress and atherosclerosis.

Woo KV, Baldwin HS.

Trends Cardiovasc Med. 2011 May;21(4):118-23. doi: 10.1016/j.tcm.2012.03.009. Review.

29.

Enhanced sensitivity for high spatial resolution lipid analysis by negative ion mode matrix assisted laser desorption ionization imaging mass spectrometry.

Angel PM, Spraggins JM, Baldwin HS, Caprioli R.

Anal Chem. 2012 Feb 7;84(3):1557-64. doi: 10.1021/ac202383m. Epub 2012 Jan 25.

30.

Endothelial differentiation by multipotent fetal mouse lung mesenchymal cells.

Yamamoto Y, Baldwin HS, Prince LS.

Stem Cells Dev. 2012 Jun 10;21(9):1455-65. doi: 10.1089/scd.2011.0219. Epub 2011 Oct 18.

31.

Nfatc1 coordinates valve endocardial cell lineage development required for heart valve formation.

Wu B, Wang Y, Lui W, Langworthy M, Tompkins KL, Hatzopoulos AK, Baldwin HS, Zhou B.

Circ Res. 2011 Jul 8;109(2):183-92. doi: 10.1161/CIRCRESAHA.111.245035. Epub 2011 May 19.

32.

What chick and mouse models have taught us about the role of the endocardium in congenital heart disease.

DeLaughter DM, Saint-Jean L, Baldwin HS, Barnett JV.

Birth Defects Res A Clin Mol Teratol. 2011 Jun;91(6):511-25. doi: 10.1002/bdra.20809. Epub 2011 Apr 28. Review.

33.

Tie1 attenuation reduces murine atherosclerosis in a dose-dependent and shear stress-specific manner.

Woo KV, Qu X, Babaev VR, Linton MF, Guzman RJ, Fazio S, Baldwin HS.

J Clin Invest. 2011 Apr;121(4):1624-35. doi: 10.1172/JCI42040. Epub 2011 Mar 7.

34.

Networked-based characterization of extracellular matrix proteins from adult mouse pulmonary and aortic valves.

Angel PM, Nusinow D, Brown CB, Violette K, Barnett JV, Zhang B, Baldwin HS, Caprioli RM.

J Proteome Res. 2011 Feb 4;10(2):812-23. doi: 10.1021/pr1009806. Epub 2010 Dec 22.

35.

The N-myc downstream regulated gene (NDRG) family: diverse functions, multiple applications.

Melotte V, Qu X, Ongenaert M, van Criekinge W, de Bruïne AP, Baldwin HS, van Engeland M.

FASEB J. 2010 Nov;24(11):4153-66. doi: 10.1096/fj.09-151464. Epub 2010 Jul 28. Review.

PMID:
20667976
36.

Abnormal embryonic lymphatic vessel development in Tie1 hypomorphic mice.

Qu X, Tompkins K, Batts LE, Puri M, Baldwin HS.

Development. 2010 Apr;137(8):1285-95. doi: 10.1242/dev.043380. Epub 2010 Mar 10. Erratum in: Development. 2014 Mar;141(6):1417. Baldwin, Scott [corrected to Baldwin, H Scott].

37.

Lung scedosporiosis in human immunodeficiency virus/acquired immunodeficiency syndrome.

Sarva ST, Manjunath SK, Baldwin HS, Robins DB, Freire AX.

Am J Med Sci. 2010 Mar;339(3):300-3. doi: 10.1097/MAJ.0b013e3181cec4be. Review.

PMID:
20220340
38.

Tbx1 is necessary for palatal elongation and elevation.

Goudy S, Law A, Sanchez G, Baldwin HS, Brown C.

Mech Dev. 2010 May-Jun;127(5-6):292-300. doi: 10.1016/j.mod.2010.03.001. Epub 2010 Mar 7.

39.

Endocardial cells are a distinct endothelial lineage derived from Flk1+ multipotent cardiovascular progenitors.

Misfeldt AM, Boyle SC, Tompkins KL, Bautch VL, Labosky PA, Baldwin HS.

Dev Biol. 2009 Sep 1;333(1):78-89. doi: 10.1016/j.ydbio.2009.06.033. Epub 2009 Jul 1.

40.

NFATc1 identifies a population of proximal tubule cell progenitors.

Langworthy M, Zhou B, de Caestecker M, Moeckel G, Baldwin HS.

J Am Soc Nephrol. 2009 Feb;20(2):311-21. doi: 10.1681/ASN.2008010094. Epub 2008 Dec 31.

41.

Cerebropulmonary dysgenetic syndrome.

Shanklin DR, Mullins AC, Baldwin HS.

Exp Mol Pathol. 2008 Oct;85(2):112-6. doi: 10.1016/j.yexmp.2008.04.006. Epub 2008 May 28.

PMID:
18603241
42.

Ndrg4 is required for normal myocyte proliferation during early cardiac development in zebrafish.

Qu X, Jia H, Garrity DM, Tompkins K, Batts L, Appel B, Zhong TP, Baldwin HS.

Dev Biol. 2008 May 15;317(2):486-96. doi: 10.1016/j.ydbio.2008.02.044. Epub 2008 Mar 6.

43.

Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia.

Boyle S, Misfeldt A, Chandler KJ, Deal KK, Southard-Smith EM, Mortlock DP, Baldwin HS, de Caestecker M.

Dev Biol. 2008 Jan 1;313(1):234-45. Epub 2007 Oct 24.

44.

Genomic imprinting of Dopa decarboxylase in heart and reciprocal allelic expression with neighboring Grb10.

Menheniott TR, Woodfine K, Schulz R, Wood AJ, Monk D, Giraud AS, Baldwin HS, Moore GE, Oakey RJ.

Mol Cell Biol. 2008 Jan;28(1):386-96. Epub 2007 Oct 29.

45.

Neural crest contribution to the cardiovascular system.

Brown CB, Baldwin HS.

Adv Exp Med Biol. 2006;589:134-54. Review.

PMID:
17076279
46.

Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function.

Brissova M, Shostak A, Shiota M, Wiebe PO, Poffenberger G, Kantz J, Chen Z, Carr C, Jerome WG, Chen J, Baldwin HS, Nicholson W, Bader DM, Jetton T, Gannon M, Powers AC.

Diabetes. 2006 Nov;55(11):2974-85.

47.

Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development.

Jiao K, Langworthy M, Batts L, Brown CB, Moses HL, Baldwin HS.

Development. 2006 Nov;133(22):4585-93. Epub 2006 Oct 18.

48.

Report of the Tennessee Task Force on Screening Newborn Infants for Critical Congenital Heart Disease.

Liske MR, Greeley CS, Law DJ, Reich JD, Morrow WR, Baldwin HS, Graham TP, Strauss AW, Kavanaugh-McHugh AL, Walsh WF; Tennessee Task Force on Screening Newborn Infants for Critical Congenital Heart Disease.

Pediatrics. 2006 Oct;118(4):e1250-6.

PMID:
17015513
49.

Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts.

Song L, Fässler R, Mishina Y, Jiao K, Baldwin HS.

Dev Biol. 2007 Jan 1;301(1):276-86. Epub 2006 Aug 9.

50.

Cardiomyocyte-specific deletion of the coxsackievirus and adenovirus receptor results in hyperplasia of the embryonic left ventricle and abnormalities of sinuatrial valves.

Chen JW, Zhou B, Yu QC, Shin SJ, Jiao K, Schneider MD, Baldwin HS, Bergelson JM.

Circ Res. 2006 Apr 14;98(7):923-30. Epub 2006 Mar 16.

PMID:
16543498

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