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Items: 1 to 50 of 88

1.

Megakaryocytes from fat: a new recipe for platelets.

Balduini A.

Blood. 2019 Feb 14;133(7):623-625. doi: 10.1182/blood-2018-12-889766. No abstract available.

PMID:
30765492
2.

EDA fibronectin-TLR4 axis sustains megakaryocyte expansion and inflammation in bone marrow fibrosis.

Malara A, Gruppi C, Abbonante V, Cattaneo D, De Marco L, Massa M, Iurlo A, Gianelli U, Balduini CL, Tira ME, Muro AF, Chauhan AK, Rosti V, Barosi G, Balduini A.

J Exp Med. 2019 Feb 7. pii: jem.20181074. doi: 10.1084/jem.20181074. [Epub ahead of print]

PMID:
30733282
3.

Mechanisms of thrombocytopenia in platelet-type Von Willebrand Disease.

Bury L, Malara A, Momi S, Petito E, Balduini A, Gresele P.

Haematologica. 2019 Jan 17. pii: haematol.2018.200378. doi: 10.3324/haematol.2018.200378. [Epub ahead of print]

4.

A new form of inherited thrombocytopenia caused by loss-of-function mutations in PTPRJ.

Marconi C, Di Buduo CA, LeVine K, Barozzi S, Faleschini M, Bozzi V, Palombo F, McKinstry S, Lassandro G, Giordano P, Noris P, Balduini CL, Savoia A, Balduini A, Pippucci T, Seri M, Katsanis N, Pecci A.

Blood. 2018 Dec 27. pii: blood-2018-07-859496. doi: 10.1182/blood-2018-07-859496. [Epub ahead of print]

PMID:
30591527
5.

Megakaryocyte Contribution to Bone Marrow Fibrosis: many Arrows in the Quiver.

Malara A, Abbonante V, Zingariello M, Migliaccio A, Balduini A.

Mediterr J Hematol Infect Dis. 2018 Nov 1;10(1):e2018068. doi: 10.4084/MJHID.2018.068. eCollection 2018. Review.

6.

Three-Dimensional Tissue Models for Studying Ex Vivo Megakaryocytopoiesis and Platelet Production.

Di Buduo CA, Abbonante V, Tozzi L, Kaplan DL, Balduini A.

Methods Mol Biol. 2018;1812:177-193. doi: 10.1007/978-1-4939-8585-2_11.

PMID:
30171579
7.

Sub-Cellular Localization of Metalloproteinases in Megakaryocytes.

Malara A, Ligi D, Di Buduo CA, Mannello F, Balduini A.

Cells. 2018 Jul 20;7(7). pii: E80. doi: 10.3390/cells7070080.

8.

Multi-channel silk sponge mimicking bone marrow vascular niche for platelet production.

Tozzi L, Laurent PA, Di Buduo CA, Mu X, Massaro A, Bretherton R, Stoppel W, Kaplan DL, Balduini A.

Biomaterials. 2018 Sep;178:122-133. doi: 10.1016/j.biomaterials.2018.06.018. Epub 2018 Jun 17.

PMID:
29920404
9.

The AMPK-activator AICAR in thyroid cancer: effects on CXCL8 secretion and on CXCL8-induced neoplastic cell migration.

Awwad O, Coperchini F, Pignatti P, Denegri M, Massara S, Croce L, Di Buduo CA, Abbonante V, Balduini A, Chiovato L, Rotondi M.

J Endocrinol Invest. 2018 Nov;41(11):1275-1282. doi: 10.1007/s40618-018-0862-8. Epub 2018 Mar 15.

PMID:
29546654
10.

Clinic, pathogenic mechanisms and drug testing of two inherited thrombocytopenias, ANKRD26-related Thrombocytopenia and MYH9-related diseases.

Balduini A, Raslova H, Di Buduo CA, Donada A, Ballmaier M, Germeshausen M, Balduini CL.

Eur J Med Genet. 2018 Nov;61(11):715-722. doi: 10.1016/j.ejmg.2018.01.014. Epub 2018 Mar 13. Review.

PMID:
29545013
11.

The spleen of patients with myelofibrosis harbors defective mesenchymal stromal cells.

Avanzini MA, Abbonante V, Catarsi P, Dambruoso I, Mantelli M, Poletto V, Lenta E, Guglielmelli P, Croce S, Cobianchi L, Jemos B, Campanelli R, Bonetti E, Di Buduo CA, Salmoiraghi S, Villani L, Massa M, Boni M, Zappatore R, Iurlo A, Rambaldi A, Vannucchi AM, Bernasconi P, Balduini A, Barosi G, Rosti V; AGIMM Investigators.

Am J Hematol. 2018 May;93(5):615-622. doi: 10.1002/ajh.25047. Epub 2018 Feb 8.

PMID:
29359451
12.

Alternatively spliced fibronectin extra domain A is required for hemangiogenic recovery upon bone marrow chemotherapy.

Malara A, Gruppi C, Celesti G, Abbonante V, Viarengo G, Laghi L, De Marco L, Muro AF, Balduini A.

Haematologica. 2018 Feb;103(2):e42-e45. doi: 10.3324/haematol.2017.173070. Epub 2017 Nov 16. No abstract available.

13.

Stromal Cell-Derived Factor-1α Promotes Endothelial Colony-Forming Cell Migration Through the Ca2+-Dependent Activation of the Extracellular Signal-Regulated Kinase 1/2 and Phosphoinositide 3-Kinase/AKT Pathways.

Zuccolo E, Di Buduo C, Lodola F, Orecchioni S, Scarpellino G, Kheder DA, Poletto V, Guerra G, Bertolini F, Balduini A, Rosti V, Moccia F.

Stem Cells Dev. 2018 Jan 1;27(1):23-34. doi: 10.1089/scd.2017.0114. Epub 2017 Dec 11.

PMID:
29121817
14.

Label free monitoring of megakaryocytic development and proplatelet formation in vitro.

Pouli D, Tozzi L, Alonzo CA, Liu Z, Kaplan DL, Balduini A, Georgakoudi I.

Biomed Opt Express. 2017 Sep 27;8(10):4742-4755. doi: 10.1364/BOE.8.004742. eCollection 2017 Oct 1.

15.

Autoantibodies in immune thrombocytopenia affect the physiological interaction between megakaryocytes and bone marrow extracellular matrix proteins.

Grodzielski M, Di Buduo CA, Goette NP, Lev PR, Soprano PM, Heller PG, Balduini A, Marta RF.

Br J Haematol. 2018 Oct;183(2):319-323. doi: 10.1111/bjh.14977. Epub 2017 Oct 26. No abstract available.

PMID:
29076144
16.

Modular flow chamber for engineering bone marrow architecture and function.

Di Buduo CA, Soprano PM, Tozzi L, Marconi S, Auricchio F, Kaplan DL, Balduini A.

Biomaterials. 2017 Nov;146:60-71. doi: 10.1016/j.biomaterials.2017.08.006. Epub 2017 Aug 8.

17.

Endothelial-to-Mesenchymal Transition in Bone Marrow and Spleen of Primary Myelofibrosis.

Erba BG, Gruppi C, Corada M, Pisati F, Rosti V, Bartalucci N, Villeval JL, Vannucchi AM, Barosi G, Balduini A, Dejana E.

Am J Pathol. 2017 Aug;187(8):1879-1892. doi: 10.1016/j.ajpath.2017.04.006.

18.

In vitro generation of platelets: Where do we stand?

Di Buduo CA, Kaplan DL, Balduini A.

Transfus Clin Biol. 2017 Sep;24(3):273-276. doi: 10.1016/j.tracli.2017.06.013. Epub 2017 Jun 29. Review.

19.

Upregulation of lysyl oxidase and adhesion to collagen of human megakaryocytes and platelets in primary myelofibrosis.

Abbonante V, Chitalia V, Rosti V, Leiva O, Matsuura S, Balduini A, Ravid K.

Blood. 2017 Aug 10;130(6):829-831. doi: 10.1182/blood-2017-04-777417. Epub 2017 Jun 7. No abstract available.

20.

A new path to platelet production through matrix sensing.

Abbonante V, Di Buduo CA, Gruppi C, De Maria C, Spedden E, De Acutis A, Staii C, Raspanti M, Vozzi G, Kaplan DL, Moccia F, Ravid K, Balduini A.

Haematologica. 2017 Jul;102(7):1150-1160. doi: 10.3324/haematol.2016.161562. Epub 2017 Apr 14.

21.

The role of the extracellular matrix in primary myelofibrosis.

Leiva O, Ng SK, Chitalia S, Balduini A, Matsuura S, Ravid K.

Blood Cancer J. 2017 Feb 3;7(2):e525. doi: 10.1038/bcj.2017.6. Review.

22.

The Plant Hormone Abscisic Acid Is a Prosurvival Factor in Human and Murine Megakaryocytes.

Malara A, Fresia C, Di Buduo CA, Soprano PM, Moccia F, Balduini C, Zocchi E, De Flora A, Balduini A.

J Biol Chem. 2017 Feb 24;292(8):3239-3251. doi: 10.1074/jbc.M116.751693. Epub 2017 Jan 3.

24.

Clinical and pathogenic features of ETV6-related thrombocytopenia with predisposition to acute lymphoblastic leukemia.

Melazzini F, Palombo F, Balduini A, De Rocco D, Marconi C, Noris P, Gnan C, Pippucci T, Bozzi V, Faleschini M, Barozzi S, Doubek M, Di Buduo CA, Kozubik KS, Radova L, Loffredo G, Pospisilova S, Alfano C, Seri M, Balduini CL, Pecci A, Savoia A.

Haematologica. 2016 Nov;101(11):1333-1342. Epub 2016 Jun 30.

25.

Studies of the interaction of ticagrelor with the P2Y13 receptor and with P2Y13-dependent pro-platelet formation by human megakaryocytes.

Björquist A, Di Buduo CA, Femia EA, Storey RF, Becker RC, Balduini A, Nylander S, Cattaneo M.

Thromb Haemost. 2016 Nov 30;116(6):1079-1088. Epub 2016 Sep 8.

26.

Effect of Interferon-γ on the Basal and the TNFα-Stimulated Secretion of CXCL8 in Thyroid Cancer Cell Lines Bearing Either the RET/PTC Rearrangement Or the BRAF V600e Mutation.

Rotondi M, Coperchini F, Awwad O, Pignatti P, Di Buduo CA, Abbonante V, Magri F, Balduini A, Chiovato L.

Mediators Inflamm. 2016;2016:8512417. doi: 10.1155/2016/8512417. Epub 2016 Jul 31.

27.

Revealing eltrombopag's promotion of human megakaryopoiesis through AKT/ERK-dependent pathway activation.

Di Buduo CA, Currao M, Pecci A, Kaplan DL, Balduini CL, Balduini A.

Haematologica. 2016 Dec;101(12):1479-1488. Epub 2016 Aug 11.

28.

Oxidative stress and thromboxane-dependent platelet activation in inflammatory bowel disease: effects of anti-TNF-α treatment.

Di Sabatino A, Santilli F, Guerci M, Simeone P, Ardizzone S, Massari A, Giuffrida P, Tripaldi R, Malara A, Liani R, Gurini E, Aronico N, Balduini A, Corazza GR, Davì G.

Thromb Haemost. 2016 Aug 30;116(3):486-95. doi: 10.1160/TH16-02-0167. Epub 2016 Jun 16.

PMID:
27305860
29.

Tie2 Expressing Monocytes in the Spleen of Patients with Primary Myelofibrosis.

Campanelli R, Fois G, Catarsi P, Poletto V, Villani L, Erba BG, Maddaluno L, Jemos B, Salmoiraghi S, Guglielmelli P, Abbonante V, Di Buduo CA, Balduini A, Iurlo A, Barosi G, Rosti V, Massa M; AGIMM Investigators.

PLoS One. 2016 Jun 9;11(6):e0156990. doi: 10.1371/journal.pone.0156990. eCollection 2016.

30.

Corrigendum: Abnormal proplatelet formation and emperipolesis in cultured human megakaryocytes from gray platelet syndrome patients.

Di Buduo CA, Alberelli MA, Glembotsky AC, Podda G, Lev PR, Cattaneo M, Landolfi R, Heller PG, Balduini A, De Candia E.

Sci Rep. 2016 Apr 29;6:25027. doi: 10.1038/srep25027. No abstract available.

31.

Brief Report: Alternative Splicing of Extra Domain A (EIIIA) of Fibronectin Plays a Tissue-Specific Role in Hematopoietic Homeostasis.

Malara A, Gruppi C, Celesti G, Romano B, Laghi L, De Marco L, Muro AF, Balduini A.

Stem Cells. 2016 Aug;34(8):2263-8. doi: 10.1002/stem.2381. Epub 2016 May 4.

32.

Abnormal proplatelet formation and emperipolesis in cultured human megakaryocytes from gray platelet syndrome patients.

Di Buduo CA, Alberelli MA, Glembostky AC, Podda G, Lev PR, Cattaneo M, Landolfi R, Heller PG, Balduini A, De Candia E.

Sci Rep. 2016 Mar 18;6:23213. doi: 10.1038/srep23213. Erratum in: Sci Rep. 2016 Apr 29;6:25027.

33.

Effect of telemonitoring of cardiac implantable electronic devices on healthcare utilization: a meta-analysis of randomized controlled trials in patients with heart failure.

Klersy C, Boriani G, De Silvestri A, Mairesse GH, Braunschweig F, Scotti V, Balduini A, Cowie MR, Leyva F; Health Economics Committee of the European Heart Rhythm Association.

Eur J Heart Fail. 2016 Feb;18(2):195-204. doi: 10.1002/ejhf.470. Epub 2016 Jan 27. Review.

34.

SLFN14-related thrombocytopenia: identification within a large series of patients with inherited thrombocytopenia.

Marconi C, Di Buduo CA, Barozzi S, Palombo F, Pardini S, Zaninetti C, Pippucci T, Noris P, Balduini A, Seri M, Pecci A.

Thromb Haemost. 2016 May 2;115(5):1076-9. doi: 10.1160/TH15-11-0884. Epub 2016 Jan 14. No abstract available.

PMID:
26769223
35.

Thrombopoietin/TGF-β1 Loop Regulates Megakaryocyte Extracellular Matrix Component Synthesis.

Abbonante V, Di Buduo CA, Gruppi C, Malara A, Gianelli U, Celesti G, Anselmo A, Laghi L, Vercellino M, Visai L, Iurlo A, Moratti R, Barosi G, Rosti V, Balduini A.

Stem Cells. 2016 Apr;34(4):1123-33. doi: 10.1002/stem.2285. Epub 2016 Jan 29.

36.

Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor.

An B, Abbonante V, Xu H, Gavriilidou D, Yoshizumi A, Bihan D, Farndale RW, Kaplan DL, Balduini A, Leitinger B, Brodsky B.

J Biol Chem. 2016 Feb 26;291(9):4343-55. doi: 10.1074/jbc.M115.674507. Epub 2015 Dec 23.

37.

TNF-α increases the membrane expression of the chemokine receptor CCR6 in thyroid tumor cells, but not in normal thyrocytes: potential role in the metastatic spread of thyroid cancer.

Coperchini F, Pignatti P, Carbone A, Bongianino R, Di Buduo CA, Leporati P, Croce L, Magri F, Balduini A, Chiovato L, Rotondi M.

Tumour Biol. 2016 Apr;37(4):5569-75. doi: 10.1007/s13277-015-4418-7. Epub 2015 Nov 17.

PMID:
26577851
38.

Differential clinical effects of different mutation subtypes in CALR-mutant myeloproliferative neoplasms.

Pietra D, Rumi E, Ferretti VV, Di Buduo CA, Milanesi C, Cavalloni C, Sant'Antonio E, Abbonante V, Moccia F, Casetti IC, Bellini M, Renna MC, Roncoroni E, Fugazza E, Astori C, Boveri E, Rosti V, Barosi G, Balduini A, Cazzola M.

Leukemia. 2016 Feb;30(2):431-8. doi: 10.1038/leu.2015.277. Epub 2015 Oct 9.

39.

Translational approaches to functional platelet production ex vivo.

Balduini A, Di Buduo CA, Kaplan DL.

Thromb Haemost. 2016 Jan;115(2):250-6. doi: 10.1160/TH15-07-0570. Epub 2015 Sep 10. Review.

PMID:
26353819
40.

Creation and implantation of acellular rat renal ECM-based scaffolds.

Peloso A, Ferrario J, Maiga B, Benzoni I, Bianco C, Citro A, Currao M, Malara A, Gaspari A, Balduini A, Abelli M, Piemonti L, Dionigi P, Orlando G, Maestri M.

Organogenesis. 2015;11(2):58-74. doi: 10.1080/15476278.2015.1072661.

41.

Human megakaryocytes confer tissue factor to a subset of shed platelets to stimulate thrombin generation.

Brambilla M, Facchinetti L, Canzano P, Rossetti L, Ferri N, Balduini A, Abbonante V, Boselli D, De Marco L, Di Minno MN, Toschi V, Corsini A, Tremoli E, Camera M.

Thromb Haemost. 2015 Aug 31;114(3):579-92. doi: 10.1160/TH14-10-0830. Epub 2015 Jun 11.

PMID:
26062685
42.

Hyaluronan based hydrogels provide an improved model to study megakaryocyte-matrix interactions.

Currao M, Malara A, Di Buduo CA, Abbonante V, Tozzi L, Balduini A.

Exp Cell Res. 2016 Aug 1;346(1):1-8. doi: 10.1016/j.yexcr.2015.05.014. Epub 2015 May 29.

43.

Altered fibronectin expression and deposition by myeloproliferative neoplasm-derived mesenchymal stromal cells.

Abbonante V, Gruppi C, Catarsi P, Avanzini MA, Tira ME, Barosi G, Rosti V, Balduini A.

Br J Haematol. 2016 Jan;172(1):140-4. doi: 10.1111/bjh.13471. Epub 2015 May 5. No abstract available.

PMID:
25940987
44.

Programmable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies.

Di Buduo CA, Wray LS, Tozzi L, Malara A, Chen Y, Ghezzi CE, Smoot D, Sfara C, Antonelli A, Spedden E, Bruni G, Staii C, De Marco L, Magnani M, Kaplan DL, Balduini A.

Blood. 2015 Apr 2;125(14):2254-64. doi: 10.1182/blood-2014-08-595561. Epub 2015 Jan 9.

45.

The secret life of a megakaryocyte: emerging roles in bone marrow homeostasis control.

Malara A, Abbonante V, Di Buduo CA, Tozzi L, Currao M, Balduini A.

Cell Mol Life Sci. 2015 Apr;72(8):1517-36. doi: 10.1007/s00018-014-1813-y. Epub 2015 Jan 9. Review.

46.

Folic acid-conjugated 4-amino-phenylboronate, a boron-containing compound designed for boron neutron capture therapy, is an unexpected agonist for human neutrophils and platelets.

Achilli C, Jadhav SA, Guidetti GF, Ciana A, Abbonante V, Malara A, Fagnoni M, Torti M, Balduini A, Balduini C, Minetti G.

Chem Biol Drug Des. 2014 May;83(5):532-40. doi: 10.1111/cbdd.12264. Epub 2014 Mar 18.

PMID:
24666508
47.

Characteristics of platelet gels combined with silk.

Pallotta I, Kluge JA, Moreau J, Calabrese R, Kaplan DL, Balduini A.

Biomaterials. 2014 Apr;35(11):3678-87. doi: 10.1016/j.biomaterials.2013.12.065. Epub 2014 Jan 27.

48.

The importance of calcium in the regulation of megakaryocyte function.

Di Buduo CA, Moccia F, Battiston M, De Marco L, Mazzucato M, Moratti R, Tanzi F, Balduini A.

Haematologica. 2014 Apr;99(4):769-78. doi: 10.3324/haematol.2013.096859. Epub 2014 Jan 24.

49.

Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation.

Bluteau D, Balduini A, Balayn N, Currao M, Nurden P, Deswarte C, Leverger G, Noris P, Perrotta S, Solary E, Vainchenker W, Debili N, Favier R, Raslova H.

J Clin Invest. 2014 Feb;124(2):580-91. doi: 10.1172/JCI71861. Epub 2014 Jan 16.

50.

Use of IVUS guided coronary stenting with drug eluting stent: a systematic review and meta-analysis of randomized controlled clinical trials and high quality observational studies.

Klersy C, Ferlini M, Raisaro A, Scotti V, Balduini A, Curti M, Bramucci E, De Silvestri A.

Int J Cardiol. 2013 Dec 5;170(1):54-63. Review.

PMID:
24383071

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