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Items: 1 to 50 of 91

1.

Occurrence and biological activity of palmitoleic acid isomers in phagocytic cells.

Astudillo AM, Meana C, Guijas C, Pereira L, Lebrero P, Balboa MA, Balsinde J.

J Lipid Res. 2018 Feb;59(2):237-249. doi: 10.1194/jlr.M079145. Epub 2017 Nov 21.

PMID:
29167413
2.

Essential Role for Ethanolamine Plasmalogen Hydrolysis in Bacterial Lipopolysaccharide Priming of Macrophages for Enhanced Arachidonic Acid Release.

Gil-de-Gómez L, Astudillo AM, Lebrero P, Balboa MA, Balsinde J.

Front Immunol. 2017 Sep 29;8:1251. doi: 10.3389/fimmu.2017.01251. eCollection 2017.

3.

Lipin-2 regulates NLRP3 inflammasome by affecting P2X7 receptor activation.

Lordén G, Sanjuán-García I, de Pablo N, Meana C, Alvarez-Miguel I, Pérez-García MT, Pelegrín P, Balsinde J, Balboa MA.

J Exp Med. 2017 Feb;214(2):511-528. doi: 10.1084/jem.20161452. Epub 2016 Dec 28.

4.

Critical role for cytosolic group IVA phospholipase A2 in early adipocyte differentiation and obesity.

Peña L, Meana C, Astudillo AM, Lordén G, Valdearcos M, Sato H, Murakami M, Balsinde J, Balboa MA.

Biochim Biophys Acta. 2016 Sep;1861(9 Pt A):1083-1095. doi: 10.1016/j.bbalip.2016.06.004. Epub 2016 Jun 16.

PMID:
27317983
5.

Foamy Monocytes Are Enriched in cis-7-Hexadecenoic Fatty Acid (16:1n-9), a Possible Biomarker for Early Detection of Cardiovascular Disease.

Guijas C, Meana C, Astudillo AM, Balboa MA, Balsinde J.

Cell Chem Biol. 2016 Jun 23;23(6):689-99. doi: 10.1016/j.chembiol.2016.04.012. Epub 2016 Jun 2.

6.

Group V secreted phospholipase A2 is upregulated by IL-4 in human macrophages and mediates phagocytosis via hydrolysis of ethanolamine phospholipids.

Rubio JM, Rodríguez JP, Gil-de-Gómez L, Guijas C, Balboa MA, Balsinde J.

J Immunol. 2015 Apr 1;194(7):3327-39. doi: 10.4049/jimmunol.1401026. Epub 2015 Feb 27.

7.

Phospholipase A2 regulation of lipid droplet formation.

Guijas C, Rodríguez JP, Rubio JM, Balboa MA, Balsinde J.

Biochim Biophys Acta. 2014 Dec;1841(12):1661-71. Review.

8.

Lipin-1 integrates lipid synthesis with proinflammatory responses during TLR activation in macrophages.

Meana C, Peña L, Lordén G, Esquinas E, Guijas C, Valdearcos M, Balsinde J, Balboa MA.

J Immunol. 2014 Nov 1;193(9):4614-22. doi: 10.4049/jimmunol.1400238. Epub 2014 Sep 24.

9.

Cytosolic group IVA and calcium-independent group VIA phospholipase A2s act on distinct phospholipid pools in zymosan-stimulated mouse peritoneal macrophages.

Gil-de-Gómez L, Astudillo AM, Guijas C, Magrioti V, Kokotos G, Balboa MA, Balsinde J.

J Immunol. 2014 Jan 15;192(2):752-62. doi: 10.4049/jimmunol.1302267. Epub 2013 Dec 13.

10.

A phosphatidylinositol species acutely generated by activated macrophages regulates innate immune responses.

Gil-de-Gómez L, Astudillo AM, Meana C, Rubio JM, Guijas C, Balboa MA, Balsinde J.

J Immunol. 2013 May 15;190(10):5169-77. doi: 10.4049/jimmunol.1203494. Epub 2013 Apr 8.

11.

Simultaneous activation of p38 and JNK by arachidonic acid stimulates the cytosolic phospholipase A2-dependent synthesis of lipid droplets in human monocytes.

Guijas C, Pérez-Chacón G, Astudillo AM, Rubio JM, Gil-de-Gómez L, Balboa MA, Balsinde J.

J Lipid Res. 2012 Nov;53(11):2343-54. doi: 10.1194/jlr.M028423. Epub 2012 Sep 4.

12.

Phospholipid sources for adrenic acid mobilization in RAW 264.7 macrophages. Comparison with arachidonic acid.

Guijas C, Astudillo AM, Gil-de-Gómez L, Rubio JM, Balboa MA, Balsinde J.

Biochim Biophys Acta. 2012 Nov;1821(11):1386-93. doi: 10.1016/j.bbalip.2012.07.010. Epub 2012 Jul 21.

13.

Lipin-2 reduces proinflammatory signaling induced by saturated fatty acids in macrophages.

Valdearcos M, Esquinas E, Meana C, Peña L, Gil-de-Gómez L, Balsinde J, Balboa MA.

J Biol Chem. 2012 Mar 30;287(14):10894-904. doi: 10.1074/jbc.M112.342915. Epub 2012 Feb 8.

14.

Dynamics of arachidonic acid mobilization by inflammatory cells.

Astudillo AM, Balgoma D, Balboa MA, Balsinde J.

Biochim Biophys Acta. 2012 Feb;1821(2):249-56. doi: 10.1016/j.bbalip.2011.11.006. Epub 2011 Dec 2. Review.

15.

Altered arachidonate distribution in macrophages from caveolin-1 null mice leading to reduced eicosanoid synthesis.

Astudillo AM, Pérez-Chacón G, Meana C, Balgoma D, Pol A, Del Pozo MA, Balboa MA, Balsinde J.

J Biol Chem. 2011 Oct 7;286(40):35299-307. doi: 10.1074/jbc.M111.277137. Epub 2011 Aug 17.

16.

Subcellular localization and role of lipin-1 in human macrophages.

Valdearcos M, Esquinas E, Meana C, Gil-de-Gómez L, Guijas C, Balsinde J, Balboa MA.

J Immunol. 2011 May 15;186(10):6004-13. doi: 10.4049/jimmunol.1003279. Epub 2011 Apr 8.

17.

Influence of cellular arachidonic acid levels on phospholipid remodeling and CoA-independent transacylase activity in human monocytes and U937 cells.

Astudillo AM, Pérez-Chacón G, Balgoma D, Gil-de-Gómez L, Ruipérez V, Guijas C, Balboa MA, Balsinde J.

Biochim Biophys Acta. 2011 Feb;1811(2):97-103. doi: 10.1016/j.bbalip.2010.11.009. Epub 2010 Dec 8.

18.

Markers of monocyte activation revealed by lipidomic profiling of arachidonic acid-containing phospholipids.

Balgoma D, Astudillo AM, Pérez-Chacón G, Montero O, Balboa MA, Balsinde J.

J Immunol. 2010 Apr 1;184(7):3857-65. doi: 10.4049/jimmunol.0902883. Epub 2010 Feb 24.

19.

Signaling role for lysophosphatidylcholine acyltransferase 3 in receptor-regulated arachidonic acid reacylation reactions in human monocytes.

Pérez-Chacón G, Astudillo AM, Ruipérez V, Balboa MA, Balsinde J.

J Immunol. 2010 Jan 15;184(2):1071-8. doi: 10.4049/jimmunol.0902257. Epub 2009 Dec 16.

20.

Lipidomic approaches to the study of phospholipase A2-regulated phospholipid fatty acid incorporation and remodeling.

Balgoma D, Montero O, Balboa MA, Balsinde J.

Biochimie. 2010 Jun;92(6):645-50. doi: 10.1016/j.biochi.2009.11.010. Epub 2009 Dec 5. Review.

21.

JNK and ceramide kinase govern the biogenesis of lipid droplets through activation of group IVA phospholipase A2.

Gubern A, Barceló-Torns M, Barneda D, López JM, Masgrau R, Picatoste F, Chalfant CE, Balsinde J, Balboa MA, Claro E.

J Biol Chem. 2009 Nov 20;284(47):32359-69. doi: 10.1074/jbc.M109.061515. Epub 2009 Sep 24.

22.

The cationic cluster of group IVA phospholipase A2 (Lys488/Lys541/Lys543/Lys544) is involved in translocation of the enzyme to phagosomes in human macrophages.

Casas J, Valdearcos M, Pindado J, Balsinde J, Balboa MA.

J Lipid Res. 2010 Feb;51(2):388-99. doi: 10.1194/jlr.M001461. Epub 2009 Aug 28.

23.

Control of free arachidonic acid levels by phospholipases A2 and lysophospholipid acyltransferases.

Pérez-Chacón G, Astudillo AM, Balgoma D, Balboa MA, Balsinde J.

Biochim Biophys Acta. 2009 Dec;1791(12):1103-13. doi: 10.1016/j.bbalip.2009.08.007. Epub 2009 Aug 26. Review.

24.

Requirement of JNK-mediated phosphorylation for translocation of group IVA phospholipase A2 to phagosomes in human macrophages.

Casas J, Meana C, Esquinas E, Valdearcos M, Pindado J, Balsinde J, Balboa MA.

J Immunol. 2009 Aug 15;183(4):2767-74. doi: 10.4049/jimmunol.0901530. Epub 2009 Jul 22.

25.

Coordinate regulation of TLR-mediated arachidonic acid mobilization in macrophages by group IVA and group V phospholipase A2s.

Ruipérez V, Astudillo AM, Balboa MA, Balsinde J.

J Immunol. 2009 Mar 15;182(6):3877-83. doi: 10.4049/jimmunol.0804003.

26.

Lipid droplet biogenesis induced by stress involves triacylglycerol synthesis that depends on group VIA phospholipase A2.

Gubern A, Barceló-Torns M, Casas J, Barneda D, Masgrau R, Picatoste F, Balsinde J, Balboa MA, Claro E.

J Biol Chem. 2009 Feb 27;284(9):5697-708. doi: 10.1074/jbc.M806173200. Epub 2008 Dec 30.

27.

Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734.

Herrero AB, Astudillo AM, Balboa MA, Cuevas C, Balsinde J, Moreno S.

Cancer Res. 2008 Dec 1;68(23):9779-87. doi: 10.1158/0008-5472.CAN-08-1981.

28.

Calcium-independent phospholipase A2-mediated formation of 1,2-diarachidonoyl-glycerophosphoinositol in monocytes.

Balgoma D, Montero O, Balboa MA, Balsinde J.

FEBS J. 2008 Dec;275(24):6180-91. doi: 10.1111/j.1742-4658.2008.06742.x. Epub 2008 Nov 5.

29.

Group IVA phospholipase A2 is necessary for the biogenesis of lipid droplets.

Gubern A, Casas J, Barceló-Torns M, Barneda D, de la Rosa X, Masgrau R, Picatoste F, Balsinde J, Balboa MA, Claro E.

J Biol Chem. 2008 Oct 10;283(41):27369-82. doi: 10.1074/jbc.M800696200. Epub 2008 Jul 16.

30.

Calcium-independent phospholipase A2 mediates proliferation of human promonocytic U937 cells.

Balboa MA, Pérez R, Balsinde J.

FEBS J. 2008 Apr;275(8):1915-24. doi: 10.1111/j.1742-4658.2008.06350.x. Epub 2008 Mar 8.

32.

Synthesis and antihypertensive effects of new methylthiomorpholinphenol derivatives.

Velázquez AM, Martínez L, Abrego V, Balboa MA, Torres LA, Camacho B, Díaz-Barriga S, Romero A, López-Castañares R, Angeles E.

Eur J Med Chem. 2008 Mar;43(3):486-500. Epub 2007 Apr 25.

PMID:
17582658
33.
34.

Calcium-independent phospholipase A2 and apoptosis.

Balsinde J, Pérez R, Balboa MA.

Biochim Biophys Acta. 2006 Nov;1761(11):1344-50. Epub 2006 Aug 3. Review.

PMID:
16962822
35.

Oxidative stress and arachidonic acid mobilization.

Balboa MA, Balsinde J.

Biochim Biophys Acta. 2006 Apr;1761(4):385-91. Epub 2006 Apr 19. Review.

PMID:
16651022
36.
37.

Overexpression of cytosolic group IVA phospholipase A2 protects cells from Ca2+-dependent death.

Casas J, Gijón MA, Vigo AG, Crespo MS, Balsinde J, Balboa MA.

J Biol Chem. 2006 Mar 3;281(9):6106-16. Epub 2005 Dec 31.

38.

Blockade of arachidonic acid incorporation into phospholipids induces apoptosis in U937 promonocytic cells.

Pérez R, Matabosch X, Llebaria A, Balboa MA, Balsinde J.

J Lipid Res. 2006 Mar;47(3):484-91. Epub 2005 Dec 2.

39.
40.

Cellular regulation and proposed biological functions of group VIA calcium-independent phospholipase A2 in activated cells.

Balsinde J, Balboa MA.

Cell Signal. 2005 Sep;17(9):1052-62. Epub 2005 Apr 7. Review.

PMID:
15993747
41.
42.

Localization of group V phospholipase A2 in caveolin-enriched granules in activated P388D1 macrophage-like cells.

Balboa MA, Shirai Y, Gaietta G, Ellisman MH, Balsinde J, Dennis EA.

J Biol Chem. 2003 Nov 28;278(48):48059-65. Epub 2003 Sep 8.

43.

Bromoenol lactone promotes cell death by a mechanism involving phosphatidate phosphohydrolase-1 rather than calcium-independent phospholipase A2.

Fuentes L, Pérez R, Nieto ML, Balsinde J, Balboa MA.

J Biol Chem. 2003 Nov 7;278(45):44683-90. Epub 2003 Sep 2.

45.

Calcium-independent phospholipase A2 is required for lysozyme secretion in U937 promonocytes.

Balboa MA, Sáez Y, Balsinde J.

J Immunol. 2003 May 15;170(10):5276-80.

46.

Expression and function of phospholipase A(2) in brain.

Balboa MA, Varela-Nieto I, Killermann Lucas K, Dennis EA.

FEBS Lett. 2002 Oct 30;531(1):12-7. Review.

47.
48.

P2Y receptors of MDCK cells: epithelial cell regulation by extracellular nucleotides.

Insel PA, Ostrom RS, Zambon AC, Hughes RJ, Balboa MA, Shehnaz D, Gregorian C, Torres B, Firestein BL, Xing M, Post SR.

Clin Exp Pharmacol Physiol. 2001 Apr;28(4):351-4.

PMID:
11339212
49.

Inflammatory activation of prostaglandin production by microglial cells antagonized by amyloid peptide.

Balboa MA, Balsinde J, Dennis EA.

Biochem Biophys Res Commun. 2001 Jan 19;280(2):558-60.

PMID:
11162555
50.

Expression of cytosolic and secreted forms of phospholipase A(2) and cyclooxygenases in human placenta, fetal membranes, and chorionic cell lines.

Johansen B, Rakkestad K, Balboa MA, Dennis EA.

Prostaglandins Other Lipid Mediat. 2000 Mar;60(4-6):119-25.

PMID:
10751642

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