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Items: 21


AAV-Mediated Expression of Broadly Neutralizing and Vaccine-like Antibodies Targeting the HIV-1 Envelope V2 Region.

van den Berg FT, Makoah NA, Ali SA, Scott TA, Mapengo RE, Mutsvunguma LZ, Mkhize NN, Lambson BE, Kgagudi PD, Crowther C, Abdool Karim SS, Balazs AB, Weinberg MS, Ely A, Arbuthnot PB, Morris L.

Mol Ther Methods Clin Dev. 2019 Jun 12;14:100-112. doi: 10.1016/j.omtm.2019.06.002. eCollection 2019 Sep 13.


Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge.

Welles HC, Jennewein MF, Mason RD, Narpala S, Wang L, Cheng C, Zhang Y, Todd JP, Lifson JD, Balazs AB, Alter G, McDermott AB, Mascola JR, Roederer M.

PLoS Pathog. 2018 Dec 5;14(12):e1007395. doi: 10.1371/journal.ppat.1007395. eCollection 2018 Dec.


Adeno-associated virus gene delivery of broadly neutralizing antibodies as prevention and therapy against HIV-1.

Lin A, Balazs AB.

Retrovirology. 2018 Oct 1;15(1):66. doi: 10.1186/s12977-018-0449-7. Review.


Antibody gene transfer with adeno-associated viral vectors as a method for HIV prevention.

Brady JM, Baltimore D, Balazs AB.

Immunol Rev. 2017 Jan;275(1):324-333. doi: 10.1111/imr.12478. Review.


Insulin-like growth factor 2 modulates murine hematopoietic stem cell maintenance through upregulation of p57.

Thomas DD, Sommer AG, Balazs AB, Beerman I, Murphy GJ, Rossi D, Mostoslavsky G.

Exp Hematol. 2016 May;44(5):422-433.e1. doi: 10.1016/j.exphem.2016.01.010. Epub 2016 Feb 10.


Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary.

Akkina R, Allam A, Balazs AB, Blankson JN, Burnett JC, Casares S, Garcia JV, Hasenkrug KJ, Kashanchi F, Kitchen SG, Klein F, Kumar P, Luster AD, Poluektova LY, Rao M, Sanders-Beer BE, Shultz LD, Zack JA.

AIDS Res Hum Retroviruses. 2016 Feb;32(2):109-19. doi: 10.1089/AID.2015.0258.


Engineering humoral immunity as prophylaxis or therapy.

Deal CE, Balazs AB.

Curr Opin Immunol. 2015 Aug;35:113-22. doi: 10.1016/j.coi.2015.06.014. Epub 2015 Jul 14. Review.


Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection.

Saunders KO, Wang L, Joyce MG, Yang ZY, Balazs AB, Cheng C, Ko SY, Kong WP, Rudicell RS, Georgiev IS, Duan L, Foulds KE, Donaldson M, Xu L, Schmidt SD, Todd JP, Baltimore D, Roederer M, Haase AT, Kwong PD, Rao SS, Mascola JR, Nabel GJ.

J Virol. 2015 Aug;89(16):8334-45.


Vectored antibody gene delivery for the prevention or treatment of HIV infection.

Deal CE, Balazs AB.

Curr Opin HIV AIDS. 2015 May;10(3):190-7. doi: 10.1097/COH.0000000000000145. Review.


Broadly neutralizing antibodies abrogate established hepatitis C virus infection.

de Jong YP, Dorner M, Mommersteeg MC, Xiao JW, Balazs AB, Robbins JB, Winer BY, Gerges S, Vega K, Labitt RN, Donovan BM, Giang E, Krishnan A, Chiriboga L, Charlton MR, Burton DR, Baltimore D, Law M, Rice CM, Ploss A.

Sci Transl Med. 2014 Sep 17;6(254):254ra129. doi: 10.1126/scitranslmed.3009512.


Vectored antibody gene delivery protects against Plasmodium falciparum sporozoite challenge in mice.

Deal C, Balazs AB, Espinosa DA, Zavala F, Baltimore D, Ketner G.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12528-32. doi: 10.1073/pnas.1407362111. Epub 2014 Aug 11.


Vectored immunoprophylaxis protects humanized mice from mucosal HIV transmission.

Balazs AB, Ouyang Y, Hong CM, Chen J, Nguyen SM, Rao DS, An DS, Baltimore D.

Nat Med. 2014 Mar;20(3):296-300. doi: 10.1038/nm.3471. Epub 2014 Feb 9.


Broad protection against influenza infection by vectored immunoprophylaxis in mice.

Balazs AB, Bloom JD, Hong CM, Rao DS, Baltimore D.

Nat Biotechnol. 2013 Jul;31(7):647-52. doi: 10.1038/nbt.2618. Epub 2013 Jun 2.


Antibody gene transfer for HIV immunoprophylaxis.

Balazs AB, West AP Jr.

Nat Immunol. 2013 Jan;14(1):1-5. doi: 10.1038/ni.2480.


Antibody-based protection against HIV infection by vectored immunoprophylaxis.

Balazs AB, Chen J, Hong CM, Rao DS, Yang L, Baltimore D.

Nature. 2011 Nov 30;481(7379):81-4. doi: 10.1038/nature10660.


Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy.

Sigal A, Kim JT, Balazs AB, Dekel E, Mayo A, Milo R, Baltimore D.

Nature. 2011 Aug 17;477(7362):95-8. doi: 10.1038/nature10347.


Dimeric 2G12 as a potent protection against HIV-1.

Luo XM, Lei MY, Feidi RA, West AP Jr, Balazs AB, Bjorkman PJ, Yang L, Baltimore D.

PLoS Pathog. 2010 Dec 16;6(12):e1001225. doi: 10.1371/journal.ppat.1001225.


Lentiviral vector delivery of human interleukin-7 (hIL-7) to human immune system (HIS) mice expands T lymphocyte populations.

O'Connell RM, Balazs AB, Rao DS, Kivork C, Yang L, Baltimore D.

PLoS One. 2010 Aug 6;5(8):e12009. doi: 10.1371/journal.pone.0012009.


MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output.

O'Connell RM, Chaudhuri AA, Rao DS, Gibson WS, Balazs AB, Baltimore D.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14235-40. doi: 10.1073/pnas.1009798107. Epub 2010 Jul 26.


Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome.

Austin KM, Gupta ML Jr, Coats SA, Tulpule A, Mostoslavsky G, Balazs AB, Mulligan RC, Daley G, Pellman D, Shimamura A.

J Clin Invest. 2008 Apr;118(4):1511-8. doi: 10.1172/JCI33764.


Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow.

Balazs AB, Fabian AJ, Esmon CT, Mulligan RC.

Blood. 2006 Mar 15;107(6):2317-21. Epub 2005 Nov 22.

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