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Items: 14

1.

Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors.

Farrell PJ, Zopf CJ, Huang HJ, Balakrishna D, Holub C, Bilakovics J, Fanjul A, Matuszkiewicz J, Plonowski A, Rolzin P, Banerjee U, Ermolieff J, Cheruvallath ZS, McBride C, Bartkowski D, Mazur C, Pachori A, Larson CJ.

J Pharmacol Exp Ther. 2019 Nov;371(2):299-308. doi: 10.1124/jpet.119.259028. Epub 2019 Sep 19.

PMID:
31537613
2.

Identification of differentially expressed transcripts at critical developmental stages in sorghum [Sorghum bicolor (L.) Moench] in relation to grain yield heterosis.

Jaikishan I, Rajendrakumar P, Hariprasanna K, Balakrishna D, Bhat BV, Tonapi VA.

3 Biotech. 2019 Jun;9(6):239. doi: 10.1007/s13205-019-1777-6. Epub 2019 May 29.

PMID:
31168432
3.

CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice.

Riopel M, Vassallo M, Ehinger E, Pattison J, Bowden K, Winkels H, Wilson M, de Jong R, Patel S, Balakrishna D, Bilakovics J, Fanjul A, Plonowski A, Larson CJ, Ley K, Cabrales P, Witztum JL, Olefsky JM, Lee YS.

Mol Metab. 2019 Feb;20:89-101. doi: 10.1016/j.molmet.2018.11.011. Epub 2018 Dec 2.

4.

Chronic fractalkine administration improves glucose tolerance and pancreatic endocrine function.

Riopel M, Seo JB, Bandyopadhyay GK, Li P, Wollam J, Chung H, Jung SR, Murphy A, Wilson M, de Jong R, Patel S, Balakrishna D, Bilakovics J, Fanjul A, Plonowski A, Koh DS, Larson CJ, Olefsky JM, Lee YS.

J Clin Invest. 2018 Apr 2;128(4):1458-1470. doi: 10.1172/JCI94330. Epub 2018 Mar 5.

5.

MET Tyrosine Kinase Inhibition Enhances the Antitumor Efficacy of an HGF Antibody.

Farrell PJ, Matuszkiewicz J, Balakrishna D, Pandya S, Hixon MS, Kamran R, Chu S, Lawson JD, Okada K, Hori A, Mizutani A, Iwata H, de Jong R, Hibner B, Vincent P.

Mol Cancer Ther. 2017 Jul;16(7):1269-1278. doi: 10.1158/1535-7163.MCT-16-0771. Epub 2017 Mar 24.

6.

Mitochondria COI-based genetic diversity of the cotton leafhopper Amrasca biguttula biguttula (Ishida) populations from India.

Kranthi S, Ghodke AB, Puttuswamy RK, Mandle M, Nandanwar R, Satija U, Pareek RK, Desai H, Udikeri SS, Balakrishna DJ, Hugar BM, Monga D, Kranthi KR.

Mitochondrial DNA A DNA Mapp Seq Anal. 2018 Mar;29(2):228-235. doi: 10.1080/24701394.2016.1275595. Epub 2017 Jan 24.

PMID:
28116945
7.

Structure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate.

Keung W, Boloor A, Brown J, Kiryanov A, Gangloff A, Lawson JD, Skene R, Hoffman I, Atienza J, Kahana J, De Jong R, Farrell P, Balakrishna D, Halkowycz P.

Bioorg Med Chem Lett. 2017 Feb 15;27(4):1099-1104. doi: 10.1016/j.bmcl.2016.12.024. Epub 2016 Dec 20.

PMID:
28082036
8.

Clinical evaluation of Varnya Gana Lepa in Vyanga (melasma).

Pallavi G, Gupta KL, Shreevathsa M, Chate VA, Balakrishna DL.

Ayu. 2015 Apr-Jun;36(2):151-6. doi: 10.4103/0974-8520.175543.

9.

Biological characterization of TAK-901, an investigational, novel, multitargeted Aurora B kinase inhibitor.

Farrell P, Shi L, Matuszkiewicz J, Balakrishna D, Hoshino T, Zhang L, Elliott S, Fabrey R, Lee B, Halkowycz P, Sang B, Ishino S, Nomura T, Teratani M, Ohta Y, Grimshaw C, Paraselli B, Satou T, de Jong R.

Mol Cancer Ther. 2013 Apr;12(4):460-70. doi: 10.1158/1535-7163.MCT-12-0657. Epub 2013 Jan 28.

10.

Development of genic-microsatellite markers for sorghum staygreen QTL using a comparative genomic approach with rice.

Srinivas G, Satish K, Murali Mohan S, Nagaraja Reddy R, Madhusudhana R, Balakrishna D, Venkatesh Bhat B, Howarth CJ, Seetharama N.

Theor Appl Genet. 2008 Jul;117(2):283-96. doi: 10.1007/s00122-008-0773-8. Epub 2008 Apr 26.

PMID:
18438637
11.

Target cell defense prevents the development of diabetes after viral infection.

Flodström M, Maday A, Balakrishna D, Cleary MM, Yoshimura A, Sarvetnick N.

Nat Immunol. 2002 Apr;3(4):373-82. Epub 2002 Mar 4.

PMID:
11919579
12.

A critical role for inducible nitric oxide synthase in host survival following coxsackievirus B4 infection.

Flodström M, Horwitz MS, Maday A, Balakrishna D, Rodriguez E, Sarvetnick N.

Virology. 2001 Mar 15;281(2):205-15.

13.

A mechanism for IL-10-mediated diabetes in the nonobese diabetic (NOD) mouse: ICAM-1 deficiency blocks accelerated diabetes.

Balasa B, La Cava A, Van Gunst K, Mocnik L, Balakrishna D, Nguyen N, Tucker L, Sarvetnick N.

J Immunol. 2000 Dec 15;165(12):7330-7.

14.

Islet-specific expression of IL-10 promotes diabetes in nonobese diabetic mice independent of Fas, perforin, TNF receptor-1, and TNF receptor-2 molecules.

Balasa B, Van Gunst K, Jung N, Balakrishna D, Santamaria P, Hanafusa T, Itoh N, Sarvetnick N.

J Immunol. 2000 Sep 1;165(5):2841-9.

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