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Items: 50


Single Hepatocyte Hepatitis B Virus Transcriptional Landscape in HIV Co-infection.

Balagopal A, Hwang HS, Grudda T, Quinn J, Sterling RK, Sulkowski MS, Thio CL.

J Infect Dis. 2019 Nov 19. pii: jiz607. doi: 10.1093/infdis/jiz607. [Epub ahead of print]


Human Hepegivirus-1: Innocent Traveler, Helpful Symbiote, or Insidious Pathogen?

Kandathil AJ, Balagopal A.

Clin Infect Dis. 2019 Oct 31. pii: ciz947. doi: 10.1093/cid/ciz947. [Epub ahead of print] No abstract available.


Fully automated organ segmentation in male pelvic CT images.

Balagopal A, Kazemifar S, Nguyen D, Lin MH, Hannan R, Owrangi A, Jiang S.

Phys Med Biol. 2018 Dec 14;63(24):245015. doi: 10.1088/1361-6560/aaf11c.


Inflammation and micronutrient biomarkers predict clinical HIV treatment failure and incident active TB in HIV-infected adults: a case-control study.

Shivakoti R, Gupte N, Tripathy S, Poongulali S, Kanyama C, Berendes S, Cardoso SW, Santos BR, La Rosa A, Mwelase N, Pillay S, Samaneka W, Riviere C, Sugandhavesa P, Bollinger RC, Balagopal A, Semba RD, Christian P, Campbell TB, Gupta A; NWCS 319 and PEARLS Study Team.

BMC Med. 2018 Sep 24;16(1):161. doi: 10.1186/s12916-018-1150-3.


No recovery of replication-competent HIV-1 from human liver macrophages.

Kandathil AJ, Sugawara S, Goyal A, Durand CM, Quinn J, Sachithanandham J, Cameron AM, Bailey JR, Perelson AS, Balagopal A.

J Clin Invest. 2018 Oct 1;128(10):4501-4509. doi: 10.1172/JCI121678. Epub 2018 Sep 10.


Hepatocellular Carcinoma Tumor Dose Response After 90Y-radioembolization With Glass Microspheres Using 90Y-SPECT/CT-Based Voxel Dosimetry.

Kappadath SC, Mikell J, Balagopal A, Baladandayuthapani V, Kaseb A, Mahvash A.

Int J Radiat Oncol Biol Phys. 2018 Oct 1;102(2):451-461. doi: 10.1016/j.ijrobp.2018.05.062. Epub 2018 Jun 2.


CMPK2 and BCL-G are associated with type 1 interferon-induced HIV restriction in humans.

El-Diwany R, Soliman M, Sugawara S, Breitwieser F, Skaist A, Coggiano C, Sangal N, Chattergoon M, Bailey JR, Siliciano RF, Blankson JN, Ray SC, Wheelan SJ, Thomas DL, Balagopal A.

Sci Adv. 2018 Aug 1;4(8):eaat0843. doi: 10.1126/sciadv.aat0843. eCollection 2018 Aug.


HIV-1 Infection and Type 1 Interferon: Navigating Through Uncertain Waters.

Sugawara S, Thomas DL, Balagopal A.

AIDS Res Hum Retroviruses. 2019 Jan;35(1):25-32. doi: 10.1089/AID.2018.0161. Epub 2018 Aug 15. Review.


Effect of baseline micronutrient and inflammation status on CD4 recovery post-cART initiation in the multinational PEARLS trial.

Shivakoti R, Ewald ER, Gupte N, Yang WT, Kanyama C, Cardoso SW, Santos B, Supparatpinyo K, Badal-Faesen S, Lama JR, Lalloo U, Zulu F, Pawar JS, Riviere C, Kumarasamy N, Hakim J, Pollard R, Detrick B, Balagopal A, Asmuth DM, Semba RD, Campbell TB, Golub J, Gupta A; NWCS 319 and ACTG PEARLS Study Team.

Clin Nutr. 2019 Jun;38(3):1303-1309. doi: 10.1016/j.clnu.2018.05.014. Epub 2018 May 29.


Presence of Human Hepegivirus-1 in a Cohort of People Who Inject Drugs.

Kandathil AJ, Thomas DL, Balagopal A.

Ann Intern Med. 2018 Jan 16;168(2):158-159. doi: 10.7326/L17-0527. No abstract available.


Presence of Human Hepegivirus-1 in a Cohort of People Who Inject Drugs.

Kandathil AJ, Breitwieser FP, Sachithanandham J, Robinson M, Mehta SH, Timp W, Salzberg SL, Thomas DL, Balagopal A.

Ann Intern Med. 2017 Jul 4;167(1):1-7. doi: 10.7326/M17-0085. Epub 2017 Jun 6.


HIV/HCV Co-infection, Liver Disease Progression, and Age-Related IGF-1 Decline.

Quinn J, Astemborski J, Mehta SH, Kirk GD, Thomas DL, Balagopal A.

Pathog Immun. 2017;2(1):50-59. doi: 10.20411/pai.v2i1.183. Epub 2017 Mar 3.


Mechanisms of HIV-1 Control.

Soliman M, Srikrishna G, Balagopal A.

Curr HIV/AIDS Rep. 2017 Jun;14(3):101-109. doi: 10.1007/s11904-017-0357-9. Review.


Intracellular HIV-1 RNA and CD4+ T-cell activation in patients starting antiretrovirals.

El-Diwany R, Breitwieser FP, Soliman M, Skaist AM, Srikrishna G, Blankson JN, Ray SC, Wheelan SJ, Thomas DL, Balagopal A.

AIDS. 2017 Jun 19;31(10):1405-1414. doi: 10.1097/QAD.0000000000001480.


Erratum to: Are T cells the only HIV-1 reservoir?

Kandathil AJ, Sugawara S, Balagopal A.

Retrovirology. 2017 Feb 8;14(1):11. doi: 10.1186/s12977-017-0333-x. No abstract available.


Are T cells the only HIV-1 reservoir?

Kandathil AJ, Sugawara S, Balagopal A.

Retrovirology. 2016 Dec 20;13(1):86. doi: 10.1186/s12977-016-0323-4. Review. Erratum in: Retrovirology. 2017 Feb 8;14 (1):11.


Continued Elevation of Interleukin-18 and Interferon-γ After Initiation of Antiretroviral Therapy and Clinical Failure in a Diverse Multicountry Human Immunodeficiency Virus Cohort.

Balagopal A, Gupte N, Shivakoti R, Cox AL, Yang WT, Berendes S, Mwelase N, Kanyama C, Pillay S, Samaneka W, Santos B, Poongulali S, Tripathy S, Riviere C, Lama JR, Cardoso SW, Sugandhavesa P, Semba RD, Hakim J, Hosseinipour MC, Kumarasamy N, Sanne I, Asmuth D, Campbell T, Bollinger RC, Gupta A.

Open Forum Infect Dis. 2016 Jul 27;3(3):ofw118. eCollection 2016 Sep.


Late onset arginase deficiency presenting with encephalopathy and midbrain hyperintensity.

Maramattom BV, Raja R, Balagopal A.

Ann Indian Acad Neurol. 2016 Jul-Sep;19(3):392-4. doi: 10.4103/0972-2327.167701.


Acute kidney injury-incidence, prognostic factors, and outcome of patients in an Intensive Care Unit in a tertiary center: A prospective observational study.

Korula S, Balakrishnan S, Sundar S, Paul V, Balagopal A.

Indian J Crit Care Med. 2016 Jun;20(6):332-6. doi: 10.4103/0972-5229.183904.


Sex-Related Differences in Inflammatory and Immune Activation Markers Before and After Combined Antiretroviral Therapy Initiation.

Mathad JS, Gupte N, Balagopal A, Asmuth D, Hakim J, Santos B, Riviere C, Hosseinipour M, Sugandhavesa P, Infante R, Pillay S, Cardoso SW, Mwelase N, Pawar J, Berendes S, Kumarasamy N, Andrade BB, Campbell TB, Currier JS, Cohn SE, Gupta A; New Work Concept Sheet 319 and AIDS Clinical Trials Group A5175 (PEARLS) Study Teams.

J Acquir Immune Defic Syndr. 2016 Oct 1;73(2):123-9. doi: 10.1097/QAI.0000000000001095.


Inflammation and Change in Body Weight With Antiretroviral Therapy Initiation in a Multinational Cohort of HIV-Infected Adults.

Mave V, Erlandson KM, Gupte N, Balagopal A, Asmuth DM, Campbell TB, Smeaton L, Kumarasamy N, Hakim J, Santos B, Riviere C, Hosseinipour MC, Sugandhavesa P, Infante R, Pillay S, Cardoso SW, Tripathy S, Mwelase N, Berendes S, Andrade BB, Thomas DL, Bollinger RC, Gupta A; ACTG PEARLS and NWCS 319 Study Team.

J Infect Dis. 2016 Jul 1;214(1):65-72. doi: 10.1093/infdis/jiw096. Epub 2016 Mar 8.


Persistently Elevated C-Reactive Protein Level in the First Year of Antiretroviral Therapy, Despite Virologic Suppression, Is Associated With HIV Disease Progression in Resource-Constrained Settings.

Shivakoti R, Yang WT, Berendes S, Mwelase N, Kanyama C, Pillay S, Samaneka W, Santos B, Poongulali S, Tripathy S, Riviere C, Lama JR, Cardoso SW, Sugandhavesa P, Balagopal A, Gupte N, Semba RD, Campbell TB, Bollinger RC, Gupta A; NWCS 319 and PEARLS Study Team.

J Infect Dis. 2016 Apr 1;213(7):1074-8. doi: 10.1093/infdis/jiv573. Epub 2015 Nov 29.


Immunologic Predictors of Liver Transplantation Outcomes in HIV-HCV Co-Infected Persons.

Balagopal A, Barin B, Quinn J, Rogers R, Sulkowski MS, Stock PG.

PLoS One. 2015 Aug 27;10(8):e0135882. doi: 10.1371/journal.pone.0135882. eCollection 2015.


Acute Hepatitis C Virus Infection Induces Consistent Changes in Circulating MicroRNAs That Are Associated with Nonlytic Hepatocyte Release.

El-Diwany R, Wasilewski LN, Witwer KW, Bailey JR, Page K, Ray SC, Cox AL, Thomas DL, Balagopal A.

J Virol. 2015 Sep;89(18):9454-64. doi: 10.1128/JVI.00955-15. Epub 2015 Jul 8.


IFNL3 genotype is associated with differential induction of IFNL3 in primary human hepatocytes.

Kurbanov F, Kim Y, Latanich R, Chaudhari P, El-Diwany R, Knabel M, Kandathil AJ, Cameron A, Cox A, Jang YY, Thomas DL, Balagopal A.

Antivir Ther. 2015;20(8):805-14. doi: 10.3851/IMP2974. Epub 2015 Jun 25.


Editorial Commentary: Another Call to Cure Hepatitis B.

Balagopal A, Thio CL.

Clin Infect Dis. 2015 Oct 15;61(8):1307-9. doi: 10.1093/cid/civ475. Epub 2015 Jun 16. No abstract available.


Pre-cART Elevation of CRP and CD4+ T-Cell Immune Activation Associated With HIV Clinical Progression in a Multinational Case-Cohort Study.

Balagopal A, Asmuth DM, Yang WT, Campbell TB, Gupte N, Smeaton L, Kanyama C, Grinsztejn B, Santos B, Supparatpinyo K, Badal-Faesen S, Lama JR, Lalloo UG, Zulu F, Pawar JS, Riviere C, Kumarasamy N, Hakim J, Li XD, Pollard RB, Semba RD, Thomas DL, Bollinger RC, Gupta A; ACTG PEARLS and NWCS 319 Study team.

J Acquir Immune Defic Syndr. 2015 Oct 1;70(2):163-71. doi: 10.1097/QAI.0000000000000696.


Editorial Commentary: Who is "Special" Now?

Balagopal A, Thomas DL.

Clin Infect Dis. 2015 Sep 1;61(5):826-8. doi: 10.1093/cid/civ382. Epub 2015 May 14. No abstract available.


C-reactive protein (CRP), interferon gamma-inducible protein 10 (IP-10), and lipopolysaccharide (LPS) are associated with risk of tuberculosis after initiation of antiretroviral therapy in resource-limited settings.

Tenforde MW, Gupte N, Dowdy DW, Asmuth DM, Balagopal A, Pollard RB, Sugandhavesa P, Lama JR, Pillay S, Cardoso SW, Pawar J, Santos B, Riviere C, Mwelase N, Kanyama C, Kumwenda J, Hakim JG, Kumarasamy N, Bollinger R, Semba RD, Campbell TB, Gupta A; ACTG PEARLS and NWCS 319 Study Group.

PLoS One. 2015 Feb 26;10(2):e0117424. doi: 10.1371/journal.pone.0117424. eCollection 2015.


Inferring viral dynamics in chronically HCV infected patients from the spatial distribution of infected hepatocytes.

Graw F, Balagopal A, Kandathil AJ, Ray SC, Thomas DL, Ribeiro RM, Perelson AS.

PLoS Comput Biol. 2014 Nov 13;10(11):e1003934. doi: 10.1371/journal.pcbi.1003934. eCollection 2014 Nov.


CD161+ MAIT cells are severely reduced in peripheral blood and lymph nodes of HIV-infected individuals independently of disease progression.

Eberhard JM, Hartjen P, Kummer S, Schmidt RE, Bockhorn M, Lehmann C, Balagopal A, Hauber J, van Lunzen J, Schulze zur Wiesch J.

PLoS One. 2014 Nov 4;9(11):e111323. doi: 10.1371/journal.pone.0111323. eCollection 2014.


Antiretroviral therapy, interferon sensitivity, and virologic setpoint in human immunodeficiency virus/hepatitis C virus coinfected patients.

Balagopal A, Kandathil AJ, Higgins YH, Wood J, Richer J, Quinn J, Eldred L, Li Z, Ray SC, Sulkowski MS, Thomas DL.

Hepatology. 2014 Aug;60(2):477-86. doi: 10.1002/hep.27158. Epub 2014 May 14.


Impact of hepatitis coinfection on hospitalization rates and causes in a multicenter cohort of persons living with HIV.

Crowell TA, Gebo KA, Balagopal A, Fleishman JA, Agwu AL, Berry SA; HIV Research Network.

J Acquir Immune Defic Syndr. 2014 Apr 1;65(4):429-37. doi: 10.1097/QAI.0000000000000059.


Use of laser capture microdissection to map hepatitis C virus-positive hepatocytes in human liver.

Kandathil AJ, Graw F, Quinn J, Hwang HS, Torbenson M, Perelson AS, Ray SC, Thomas DL, Ribeiro RM, Balagopal A.

Gastroenterology. 2013 Dec;145(6):1404-13.e1-10. doi: 10.1053/j.gastro.2013.08.034. Epub 2013 Aug 22.


Liver stiffness is associated with monocyte activation in HIV-infected Ugandans without viral hepatitis.

Redd AD, Wendel SK, Grabowski MK, Ocama P, Kiggundu V, Bbosa F, Boaz I, Balagopal A, Reynolds SJ, Gray RH, Serwadda D, Kirk GD, Quinn TC, Stabinski L.

AIDS Res Hum Retroviruses. 2013 Jul;29(7):1026-30. doi: 10.1089/AID.2013.0004. Epub 2013 May 8.


HIV, age, and the severity of hepatitis C virus-related liver disease: a cohort study.

Kirk GD, Mehta SH, Astemborski J, Galai N, Washington J, Higgins Y, Balagopal A, Thomas DL.

Ann Intern Med. 2013 May 7;158(9):658-66. doi: 10.7326/0003-4819-158-9-201305070-00604.


Detection of microbial translocation in HIV and SIV infection using the Limulus amebocyte lysate assay is masked by serum and plasma.

Balagopal A, Gama L, Franco V, Russell JN, Quinn J, Higgins Y, Smeaton LM, Clements JE, Thomas DL, Gupta A; NWCS 319 and ACTG 5175 study team.

PLoS One. 2012;7(8):e41258. Epub 2012 Aug 1.


Laser captured hepatocytes show association of butyrylcholinesterase gene loss and fibrosis progression in hepatitis C-infected drug users.

Munshaw S, Hwang HS, Torbenson M, Quinn J, Hansen KD, Astemborski J, Mehta SH, Ray SC, Thomas DL, Balagopal A.

Hepatology. 2012 Aug;56(2):544-54. doi: 10.1002/hep.25655. Epub 2012 Jul 6.


The transhepatic endotoxin gradient is present despite liver cirrhosis and is attenuated after transjugular portosystemic shunt (TIPS).

Benten D, Schulze zur Wiesch J, Sydow K, Koops A, Buggisch P, Böger RH, Gaydos CA, Won H, Franco V, Lohse AW, Ray SC, Balagopal A.

BMC Gastroenterol. 2011 Oct 6;11:107. doi: 10.1186/1471-230X-11-107.


IL28B and the control of hepatitis C virus infection.

Balagopal A, Thomas DL, Thio CL.

Gastroenterology. 2010 Dec;139(6):1865-76. doi: 10.1053/j.gastro.2010.10.004. Epub 2010 Oct 13. Review.


Kupffer cells are depleted with HIV immunodeficiency and partially recovered with antiretroviral immune reconstitution.

Balagopal A, Ray SC, De Oca RM, Sutcliffe CG, Vivekanandan P, Higgins Y, Mehta SH, Moore RD, Sulkowski MS, Thomas DL, Torbenson MS.

AIDS. 2009 Nov 27;23(18):2397-404. doi: 10.1097/QAD.0b013e3283324344.


Detection and treatment of Strongyloides hyperinfection syndrome following lung transplantation.

Balagopal A, Mills L, Shah A, Subramanian A.

Transpl Infect Dis. 2009 Apr;11(2):149-54. doi: 10.1111/j.1399-3062.2009.00375.x. Epub 2009 Feb 22. Review.


Human immunodeficiency virus-related microbial translocation and progression of hepatitis C.

Balagopal A, Philp FH, Astemborski J, Block TM, Mehta A, Long R, Kirk GD, Mehta SH, Cox AL, Thomas DL, Ray SC.

Gastroenterology. 2008 Jul;135(1):226-33. doi: 10.1053/j.gastro.2008.03.022. Epub 2008 Mar 29.


Clostridium difficile: new therapeutic options.

Balagopal A, Sears CL.

Curr Opin Pharmacol. 2007 Oct;7(5):455-8. Epub 2007 Jul 23. Review.


AcpA is a Francisella acid phosphatase that affects intramacrophage survival and virulence.

Mohapatra NP, Balagopal A, Soni S, Schlesinger LS, Gunn JS.

Infect Immun. 2007 Jan;75(1):390-6. Epub 2006 Oct 23.


Characterization of the receptor-ligand pathways important for entry and survival of Francisella tularensis in human macrophages.

Balagopal A, MacFarlane AS, Mohapatra N, Soni S, Gunn JS, Schlesinger LS.

Infect Immun. 2006 Sep;74(9):5114-25.


Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP.

Parsa KV, Ganesan LP, Rajaram MV, Gavrilin MA, Balagopal A, Mohapatra NP, Wewers MD, Schlesinger LS, Gunn JS, Tridandapani S.

PLoS Pathog. 2006 Jul;2(7):e71.


Mycobacterium tuberculosis binding to human surfactant proteins A and D, fibronectin, and small airway epithelial cells under shear conditions.

Hall-Stoodley L, Watts G, Crowther JE, Balagopal A, Torrelles JB, Robison-Cox J, Bargatze RF, Harmsen AG, Crouch EC, Schlesinger LS.

Infect Immun. 2006 Jun;74(6):3587-96.

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