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Items: 42

1.

A Chemo-enzymatically Linked Bispecific Antibody Retargets T Cells to a Sialylated Epitope on CD43 in Acute Myeloid Leukemia.

Bartels L, de Jong G, Gillissen MA, Yasuda E, Kattler V, Bru C, Fatmawati C, van Hal-van Veen SE, Cercel MG, Moiset G, Bakker AQ, van Helden PM, Villaudy J, Hazenberg MD, Spits H, Wagner K.

Cancer Res. 2019 Jul 1;79(13):3372-3382. doi: 10.1158/0008-5472.CAN-18-0189. Epub 2019 May 7.

PMID:
31064847
2.

BOB.1 controls memory B-cell fate in the germinal center reaction.

Levels MJ, Fehres CM, van Baarsen LGM, van Uden NOP, Germar K, O'Toole TG, Blijdorp ICJ, Semmelink JF, Doorenspleet ME, Bakker AQ, Krasavin M, Tomilin A, Brouard S, Spits H, Baeten DLP, Yeremenko NG.

J Autoimmun. 2019 Jul;101:131-144. doi: 10.1016/j.jaut.2019.04.011. Epub 2019 Apr 30.

3.

Establishment of Systems to Enable Isolation of Porcine Monoclonal Antibodies Broadly Neutralizing the Porcine Reproductive and Respiratory Syndrome Virus.

Goldeck D, Perry DM, Hayes JWP, Johnson LPM, Young JE, Roychoudhury P, McLuskey EL, Moffat K, Bakker AQ, Kwakkenbos MJ, Frossard JP, Rowland RRR, Murtaugh MP, Graham SP.

Front Immunol. 2019 Mar 27;10:572. doi: 10.3389/fimmu.2019.00572. eCollection 2019.

4.

Cross-genotype AR3-specific neutralizing antibodies confer long-term protection in injecting drug users after HCV clearance.

Merat SJ, Bru C, van de Berg D, Molenkamp R, Tarr AW, Koekkoek S, Kootstra NA, Prins M, Ball JK, Bakker AQ, de Jong MD, Spits H, Beaumont T, Schinkel J.

J Hepatol. 2019 Jul;71(1):14-24. doi: 10.1016/j.jhep.2019.02.013. Epub 2019 Feb 21.

PMID:
30797052
5.

Generation and Characterization of Anti-Citrullinated Protein Antibody-Producing B Cell Clones From Rheumatoid Arthritis Patients.

Germar K, Fehres CM, Scherer HU, van Uden N, Pollastro S, Yeremenko N, Hansson M, Kerkman PF, van der Voort EIH, Reed E, Maassen H, Kwakkenbos MJ, Bakker AQ, Klareskog L, Malmström V, de Vries N, Toes REM, Lundberg K, Spits H, Baeten DL.

Arthritis Rheumatol. 2019 Mar;71(3):340-350. doi: 10.1002/art.40739. Epub 2019 Feb 2.

PMID:
30277007
6.

Patient-derived antibody recognizes a unique CD43 epitope expressed on all AML and has antileukemia activity in mice.

Gillissen MA, de Jong G, Kedde M, Yasuda E, Levie SE, Moiset G, Hensbergen PJ, Bakker AQ, Wagner K, Villaudy J, van Helden PM, Spits H, Hazenberg MD.

Blood Adv. 2017 Aug 18;1(19):1551-1564. doi: 10.1182/bloodadvances.2017008342. eCollection 2017 Aug 22.

7.

AML-specific cytotoxic antibodies in patients with durable graft-versus-leukemia responses.

Gillissen MA, Kedde M, Jong G, Moiset G, Yasuda E, Levie SE, Bakker AQ, Claassen YB, Wagner K, Böhne M, Hensbergen PJ, Speijer D, van Helden PM, Beaumont T, Spits H, Hazenberg MD.

Blood. 2018 Jan 4;131(1):131-143. doi: 10.1182/blood-2017-02-768762. Epub 2017 Oct 23.

PMID:
29061569
8.

Multiplex flow cytometry-based assay to study the breadth of antibody responses against E1E2 glycoproteins of hepatitis C virus.

Merat SJ, van de Berg D, Bru C, Yasuda E, Breij E, Kootstra N, Prins M, Molenkamp R, Bakker AQ, de Jong MD, Spits H, Schinkel J, Beaumont T.

J Immunol Methods. 2018 Mar;454:15-26. doi: 10.1016/j.jim.2017.07.015. Epub 2017 Aug 30.

PMID:
28855105
9.

Broadly Reactive Anti-Respiratory Syncytial Virus G Antibodies from Exposed Individuals Effectively Inhibit Infection of Primary Airway Epithelial Cells.

Cortjens B, Yasuda E, Yu X, Wagner K, Claassen YB, Bakker AQ, van Woensel JBM, Beaumont T.

J Virol. 2017 Apr 28;91(10). pii: e02357-16. doi: 10.1128/JVI.02357-16. Print 2017 May 15.

10.

Corrigendum: Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming.

Kwakkenbos MJ, Diehl SA, Yasuda E, Bakker AQ, van Geelen CM, Lukens MV, van Bleek GM, Widjojoatmodjo MN, Bogers WM, Mei H, Radbruch A, Scheeren FA, Spits H, Beaumont T.

Nat Med. 2016 Dec 6;22(12):1502. doi: 10.1038/nm1216-1502a. No abstract available.

PMID:
27923028
11.

Hepatitis C virus Broadly Neutralizing Monoclonal Antibodies Isolated 25 Years after Spontaneous Clearance.

Merat SJ, Molenkamp R, Wagner K, Koekkoek SM, van de Berg D, Yasuda E, Böhne M, Claassen YB, Grady BP, Prins M, Bakker AQ, de Jong MD, Spits H, Schinkel J, Beaumont T.

PLoS One. 2016 Oct 24;11(10):e0165047. doi: 10.1371/journal.pone.0165047. eCollection 2016.

12.

Multiple capsid-stabilizing interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis.

Shakeel S, Westerhuis BM, Domanska A, Koning RI, Matadeen R, Koster AJ, Bakker AQ, Beaumont T, Wolthers KC, Butcher SJ.

Nat Commun. 2016 Jul 20;7:11387. doi: 10.1038/ncomms11387.

13.

AML relapse after rituximab treatment for GvHD: crucial role for B cells in GvL responses.

Gillissen MA, de Jong G, Levie SE, Yasuda E, Bakker AQ, Evers LM, Pals ST, Huisman C, van Helden PM, Spits H, Hazenberg MD.

Bone Marrow Transplant. 2016 Sep;51(9):1245-8. doi: 10.1038/bmt.2016.90. Epub 2016 Apr 18. No abstract available.

PMID:
27088384
14.

Structural Basis of Human Parechovirus Neutralization by Human Monoclonal Antibodies.

Shakeel S, Westerhuis BM, Ora A, Koen G, Bakker AQ, Claassen Y, Wagner K, Beaumont T, Wolthers KC, Butcher SJ.

J Virol. 2015 Sep;89(18):9571-80. doi: 10.1128/JVI.01429-15. Epub 2015 Jul 8.

15.

Human Memory B Cells Producing Potent Cross-Neutralizing Antibodies against Human Parechovirus: Implications for Prevalence, Treatment, and Diagnosis.

Westerhuis BM, Benschop KS, Koen G, Claassen YB, Wagner K, Bakker AQ, Wolthers KC, Beaumont T.

J Virol. 2015 Aug;89(15):7457-64. doi: 10.1128/JVI.01079-15. Epub 2015 May 6.

16.

Bispecific antibody generated with sortase and click chemistry has broad antiinfluenza virus activity.

Wagner K, Kwakkenbos MJ, Claassen YB, Maijoor K, Böhne M, van der Sluijs KF, Witte MD, van Zoelen DJ, Cornelissen LA, Beaumont T, Bakker AQ, Ploegh HL, Spits H.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16820-5. doi: 10.1073/pnas.1408605111. Epub 2014 Nov 10.

17.

A common solution to group 2 influenza virus neutralization.

Friesen RH, Lee PS, Stoop EJ, Hoffman RM, Ekiert DC, Bhabha G, Yu W, Juraszek J, Koudstaal W, Jongeneelen M, Korse HJ, Ophorst C, Brinkman-van der Linden EC, Throsby M, Kwakkenbos MJ, Bakker AQ, Beaumont T, Spits H, Kwaks T, Vogels R, Ward AB, Goudsmit J, Wilson IA.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):445-50. doi: 10.1073/pnas.1319058110. Epub 2013 Dec 11.

18.

Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.

McLellan JS, Chen M, Joyce MG, Sastry M, Stewart-Jones GB, Yang Y, Zhang B, Chen L, Srivatsan S, Zheng A, Zhou T, Graepel KW, Kumar A, Moin S, Boyington JC, Chuang GY, Soto C, Baxa U, Bakker AQ, Spits H, Beaumont T, Zheng Z, Xia N, Ko SY, Todd JP, Rao S, Graham BS, Kwong PD.

Science. 2013 Nov 1;342(6158):592-8. doi: 10.1126/science.1243283. Erratum in: Science. 2013 Nov 22;342(6161):931.

19.

Novel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins.

Hazenbos WL, Kajihara KK, Vandlen R, Morisaki JH, Lehar SM, Kwakkenbos MJ, Beaumont T, Bakker AQ, Phung Q, Swem LR, Ramakrishnan S, Kim J, Xu M, Shah IM, Diep BA, Sai T, Sebrell A, Khalfin Y, Oh A, Koth C, Lin SJ, Lee BC, Strandh M, Koefoed K, Andersen PS, Spits H, Brown EJ, Tan MW, Mariathasan S.

PLoS Pathog. 2013;9(10):e1003653. doi: 10.1371/journal.ppat.1003653. Epub 2013 Oct 10.

20.

Genetic manipulation of B cells for the isolation of rare therapeutic antibodies from the human repertoire.

Kwakkenbos MJ, Bakker AQ, van Helden PM, Wagner K, Yasuda E, Spits H, Beaumont T.

Methods. 2014 Jan 1;65(1):38-43. doi: 10.1016/j.ymeth.2013.07.002. Epub 2013 Jul 15.

PMID:
23867338
21.

Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo.

Legrand N, Huntington ND, Nagasawa M, Bakker AQ, Schotte R, Strick-Marchand H, de Geus SJ, Pouw SM, Böhne M, Voordouw A, Weijer K, Di Santo JP, Spits H.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13224-9. doi: 10.1073/pnas.1101398108. Epub 2011 Jul 25.

22.

Synergy between IL-15 and Id2 promotes the expansion of human NK progenitor cells, which can be counteracted by the E protein HEB required to drive T cell development.

Schotte R, Dontje W, Nagasawa M, Yasuda Y, Bakker AQ, Spits H, Blom B.

J Immunol. 2010 Jun 15;184(12):6670-9. doi: 10.4049/jimmunol.0901508. Epub 2010 May 10.

23.

Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming.

Kwakkenbos MJ, Diehl SA, Yasuda E, Bakker AQ, van Geelen CM, Lukens MV, van Bleek GM, Widjojoatmodjo MN, Bogers WM, Mei H, Radbruch A, Scheeren FA, Spits H, Beaumont T.

Nat Med. 2010 Jan;16(1):123-8. doi: 10.1038/nm.2071. Epub 2009 Dec 20. Erratum in: Nat Med. 2016 Dec 6;22(12 ):1502.

24.

IL-7 enhances thymic human T cell development in "human immune system" Rag2-/-IL-2Rgammac-/- mice without affecting peripheral T cell homeostasis.

van Lent AU, Dontje W, Nagasawa M, Siamari R, Bakker AQ, Pouw SM, Maijoor KA, Weijer K, Cornelissen JJ, Blom B, Di Santo JP, Spits H, Legrand N.

J Immunol. 2009 Dec 15;183(12):7645-55. doi: 10.4049/jimmunol.0902019.

25.

Identification of target membrane proteins as detected by phage antibodies.

Geuijen CA, Bakker AQ, de Kruif J.

Methods Mol Biol. 2009;528:141-58. doi: 10.1007/978-1-60327-310-7_11.

PMID:
19153691
26.

Isolation and characterization of human monoclonal antibodies from individuals infected with West Nile Virus.

Throsby M, Geuijen C, Goudsmit J, Bakker AQ, Korimbocus J, Kramer RA, Clijsters-van der Horst M, de Jong M, Jongeneelen M, Thijsse S, Smit R, Visser TJ, Bijl N, Marissen WE, Loeb M, Kelvin DJ, Preiser W, ter Meulen J, de Kruif J.

J Virol. 2006 Jul;80(14):6982-92.

27.

Human monoclonal antibody combination against SARS coronavirus: synergy and coverage of escape mutants.

ter Meulen J, van den Brink EN, Poon LL, Marissen WE, Leung CS, Cox F, Cheung CY, Bakker AQ, Bogaards JA, van Deventer E, Preiser W, Doerr HW, Chow VT, de Kruif J, Peiris JS, Goudsmit J.

PLoS Med. 2006 Jul;3(7):e237.

28.

The human antibody repertoire specific for rabies virus glycoprotein as selected from immune libraries.

Kramer RA, Marissen WE, Goudsmit J, Visser TJ, Clijsters-Van der Horst M, Bakker AQ, de Jong M, Jongeneelen M, Thijsse S, Backus HH, Rice AB, Weldon WC, Rupprecht CE, Dietzschold B, Bakker AB, de Kruif J.

Eur J Immunol. 2005 Jul;35(7):2131-45.

29.

C-type lectin-like molecule-1: a novel myeloid cell surface marker associated with acute myeloid leukemia.

Bakker AB, van den Oudenrijn S, Bakker AQ, Feller N, van Meijer M, Bia JA, Jongeneelen MA, Visser TJ, Bijl N, Geuijen CA, Marissen WE, Radosevic K, Throsby M, Schuurhuis GJ, Ossenkoppele GJ, de Kruif J, Goudsmit J, Kruisbeek AM.

Cancer Res. 2004 Nov 15;64(22):8443-50.

30.
31.

NFAT-controlled expression of GFP permits visualization and isolation of antigen-stimulated primary human T cells.

Hooijberg E, Bakker AQ, Ruizendaal JJ, Spits H.

Blood. 2000 Jul 15;96(2):459-66.

PMID:
10887106
32.

Genetic modification of human B-cell development: B-cell development is inhibited by the dominant negative helix loop helix factor Id3.

Jaleco AC, Stegmann AP, Heemskerk MH, Couwenberg F, Bakker AQ, Weijer K, Spits H.

Blood. 1999 Oct 15;94(8):2637-46.

PMID:
10515867
33.

HGF/SF and its receptor c-MET play a minor role in the dissemination of human B-lymphoma cells in SCID mice.

Weimar IS, Weijer K, van den Berk PC, Muller EJ, Miranda N, Bakker AQ, Heemskerk MH, Hekman A, de Gast GC, Gerritsen WR.

Br J Cancer. 1999 Sep;81(1):43-53.

34.

Enrichment of an antigen-specific T cell response by retrovirally transduced human dendritic cells.

Heemskerk MH, Hooijberg E, Ruizendaal JJ, van der Weide MM, Kueter E, Bakker AQ, Schumacher TN, Spits H.

Cell Immunol. 1999 Jul 10;195(1):10-7.

PMID:
10433792
35.

Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors.

Blom B, Heemskerk MH, Verschuren MC, van Dongen JJ, Stegmann AP, Bakker AQ, Couwenberg F, Res PC, Spits H.

EMBO J. 1999 May 17;18(10):2793-802.

36.

TCR gene rearrangements and expression of the pre-T cell receptor complex during human T-cell differentiation.

Blom B, Verschuren MC, Heemskerk MH, Bakker AQ, van Gastel-Mol EJ, Wolvers-Tettero IL, van Dongen JJ, Spits H.

Blood. 1999 May 1;93(9):3033-43.

PMID:
10216100
37.

Green fluorescent protein as a selectable marker of fibronectin-facilitated retroviral gene transfer in primary human T lymphocytes.

Dardalhon V, Noraz N, Pollok K, Rebouissou C, Boyer M, Bakker AQ, Spits H, Taylor N.

Hum Gene Ther. 1999 Jan 1;10(1):5-14.

PMID:
10022526
38.

Functional analysis of Ran/TC4 as a protein regulating T-cell costimulation.

Nieland JD, Haks MC, Kremers BL, Leupers TJ, Bakker AQ, Offringa R, Kruisbeek AM.

Cancer Gene Ther. 1998 Sep-Oct;5(5):259-73.

PMID:
9824045
39.

Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3.

Heemskerk MH, Blom B, Nolan G, Stegmann AP, Bakker AQ, Weijer K, Res PC, Spits H.

J Exp Med. 1997 Nov 3;186(9):1597-602.

40.

Expression of tyrosine kinase gene in mouse thymic stromal cells.

Rinke de Wit TF, Izon DJ, Revilla C, Oosterwegel M, Bakker AQ, van Ewijk W, Kruisbeek AM.

Int Immunol. 1996 Nov;8(11):1787-95.

PMID:
8943574
41.
42.

DNA sequence analysis of spontaneous mutations at a LacZ transgene integrated on the mouse X chromosome.

Gossen JA, de Leeuw WJ, Bakker AQ, Vijg J.

Mutagenesis. 1993 May;8(3):243-7.

PMID:
8332087

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