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Items: 1 to 50 of 354

1.

Deep multiomics profiling of brain tumors identifies signaling networks downstream of cancer driver genes.

Wang H, Diaz AK, Shaw TI, Li Y, Niu M, Cho JH, Paugh BS, Zhang Y, Sifford J, Bai B, Wu Z, Tan H, Zhou S, Hover LD, Tillman HS, Shirinifard A, Thiagarajan S, Sablauer A, Pagala V, High AA, Wang X, Li C, Baker SJ, Peng J.

Nat Commun. 2019 Aug 16;10(1):3718. doi: 10.1038/s41467-019-11661-4.

2.

Investigating the role of prostaglandin receptor isoform EP4b in zebrafish ovulation.

Baker SJC, Van Der Kraak G.

Gen Comp Endocrinol. 2019 Jul 23;283:113228. doi: 10.1016/j.ygcen.2019.113228. [Epub ahead of print]

PMID:
31348957
3.

p53: a tumor suppressor hiding in plain sight.

Baker SJ, Vogelstein B.

J Mol Cell Biol. 2019 Jul 19;11(7):536-538. doi: 10.1093/jmcb/mjz068. No abstract available.

PMID:
31276589
4.

CNS penetration of the CDK4/6 inhibitor ribociclib in non-tumor bearing mice and mice bearing pediatric brain tumors.

Patel YT, Davis A, Baker SJ, Campagne O, Stewart CF.

Cancer Chemother Pharmacol. 2019 Aug;84(2):447-452. doi: 10.1007/s00280-019-03864-9. Epub 2019 May 11.

PMID:
31079218
5.

Effects of music, video, and 360-degree video on cycle ergometer exercise at the ventilatory threshold.

Bird JM, Karageorghis CI, Baker SJ, Brookes DA.

Scand J Med Sci Sports. 2019 Aug;29(8):1161-1173. doi: 10.1111/sms.13453. Epub 2019 Jun 3. Erratum in: Scand J Med Sci Sports. 2019 Oct;29(10):1655.

PMID:
31050032
6.

Correction to: H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo.

Silveira AB, Kasper LH, Fan Y, Jin H, Wu G, Shaw TI, Zhu X, Larson JD, Easton J, Shao Y, Yergeau DA, Rosencrance C, Boggs K, Rusch MC, Ding L, Zhang J, Finkelstein D, Noyes RM, Russell BL, Xu B, Broniscer A, Wetmore C, Pounds SB, Ellison DW, Zhang J, Baker SJ.

Acta Neuropathol. 2019 Jun;137(6):1021. doi: 10.1007/s00401-019-02006-y. Epub 2019 Apr 11.

PMID:
30976974
7.

Rigosertib ameliorates the effects of oncogenic KRAS signaling in a murine model of myeloproliferative neoplasia.

Baker SJ, Cosenza SC, Ramana Reddy MV, Premkumar Reddy E.

Oncotarget. 2019 Mar 8;10(20):1932-1942. doi: 10.18632/oncotarget.26735. eCollection 2019 Mar 8.

8.

Preoperative opioid use and postoperative pain associated with surgical readmissions.

Dasinger EA, Graham LA, Wahl TS, Richman JS, Baker SJ, Hawn MT, Hernandez-Boussard T, Rosen AK, Mull HJ, Copeland LA, Whittle JC, Burns EA, Morris MS.

Am J Surg. 2019 Feb 28. pii: S0002-9610(18)31532-0. doi: 10.1016/j.amjsurg.2019.02.033. [Epub ahead of print]

PMID:
30879796
9.

H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo.

Silveira AB, Kasper LH, Fan Y, Jin H, Wu G, Shaw TI, Zhu X, Larson JD, Easton J, Shao Y, Yergeau DA, Rosencrance C, Boggs K, Rusch MC, Ding L, Zhang J, Finkelstein D, Noyes RM, Russell BL, Xu B, Broniscer A, Wetmore C, Pounds SB, Ellison DW, Zhang J, Baker SJ.

Acta Neuropathol. 2019 Apr;137(4):637-655. doi: 10.1007/s00401-019-01975-4. Epub 2019 Feb 15. Erratum in: Acta Neuropathol. 2019 Jun;137(6):1021.

PMID:
30770999
10.

Targeting protein kinase CK2 and CDK4/6 pathways with a multi-kinase inhibitor ON108110 suppresses pro-survival signaling and growth in mantle cell lymphoma and T-acute lymphoblastic leukemia.

Padgaonkar A, Rechkoblit O, Vasquez-Del Carpio R, Pallela V, Venkata Subbaiah D, Cosenza SC, Baker SJ, Ramana Reddy MV, Aggarwal A, Reddy EP.

Oncotarget. 2018 Dec 28;9(102):37753-37765. doi: 10.18632/oncotarget.26514. eCollection 2018 Dec 28.

11.

Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression.

Larson JD, Kasper LH, Paugh BS, Jin H, Wu G, Kwon CH, Fan Y, Shaw TI, Silveira AB, Qu C, Xu R, Zhu X, Zhang J, Russell HR, Peters JL, Finkelstein D, Xu B, Lin T, Tinkle CL, Patay Z, Onar-Thomas A, Pounds SB, McKinnon PJ, Ellison DW, Zhang J, Baker SJ.

Cancer Cell. 2019 Jan 14;35(1):140-155.e7. doi: 10.1016/j.ccell.2018.11.015. Epub 2018 Dec 27.

PMID:
30595505
12.

Technologies to address antimicrobial resistance.

Baker SJ, Payne DJ, Rappuoli R, De Gregorio E.

Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):12887-12895. doi: 10.1073/pnas.1717160115.

13.

Engineering Inducible Knock-In Mice to Model Oncogenic Brain Tumor Mutations from Endogenous Loci.

Larson JD, Baker SJ.

Methods Mol Biol. 2019;1869:207-230. doi: 10.1007/978-1-4939-8805-1_18.

14.

Antibacterial activities of plasma from the common (Chelydra serpentina) and alligator snapping turtle (Macrochelys temminckii).

Baker SJ, Kessler EJ, Merchant ME.

J Exp Zool A Ecol Integr Physiol. 2019 Feb;331(2):85-92. doi: 10.1002/jez.2237. Epub 2018 Oct 1.

PMID:
30273972
15.

Structure and evolution of double minutes in diagnosis and relapse brain tumors.

Xu K, Ding L, Chang TC, Shao Y, Chiang J, Mulder H, Wang S, Shaw TI, Wen J, Hover L, McLeod C, Wang YD, Easton J, Rusch M, Dalton J, Downing JR, Ellison DW, Zhang J, Baker SJ, Wu G.

Acta Neuropathol. 2019 Jan;137(1):123-137. doi: 10.1007/s00401-018-1912-1. Epub 2018 Sep 28.

16.

Over treatment and inadequate trial protocols.

Baker GJ, Baker SJ.

Vet Rec. 2018 Jul 21;183(3):99. doi: 10.1136/vr.k3159. No abstract available. Erratum in: Vet Rec. 2018 Jul 28;183(4):136.

PMID:
30026358
17.

Antibacterial properties of plasma from the prairie rattlesnake (Crotalus viridis).

Baker SJ, Merchant ME.

Dev Comp Immunol. 2018 Jul;84:273-278. doi: 10.1016/j.dci.2018.03.002. Epub 2018 Mar 3.

PMID:
29510163
18.

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.

Mackay A, Burford A, Carvalho D, Izquierdo E, Fazal-Salom J, Taylor KR, Bjerke L, Clarke M, Vinci M, Nandhabalan M, Temelso S, Popov S, Molinari V, Raman P, Waanders AJ, Han HJ, Gupta S, Marshall L, Zacharoulis S, Vaidya S, Mandeville HC, Bridges LR, Martin AJ, Al-Sarraj S, Chandler C, Ng HK, Li X, Mu K, Trabelsi S, Brahim DH, Kisljakov AN, Konovalov DM, Moore AS, Carcaboso AM, Sunol M, de Torres C, Cruz O, Mora J, Shats LI, Stavale JN, Bidinotto LT, Reis RM, Entz-Werle N, Farrell M, Cryan J, Crimmins D, Caird J, Pears J, Monje M, Debily MA, Castel D, Grill J, Hawkins C, Nikbakht H, Jabado N, Baker SJ, Pfister SM, Jones DTW, Fouladi M, von Bueren AO, Baudis M, Resnick A, Jones C.

Cancer Cell. 2017 Oct 9;32(4):520-537.e5. doi: 10.1016/j.ccell.2017.08.017. Epub 2017 Sep 28.

19.

Charcoal evidence that rising atmospheric oxygen terminated Early Jurassic ocean anoxia.

Baker SJ, Hesselbo SP, Lenton TM, Duarte LV, Belcher CM.

Nat Commun. 2017 May 12;8:15018. doi: 10.1038/ncomms15018.

20.

Climatic and geographic predictors of life history variation in Eastern Massasauga (Sistrurus catenatus): A range-wide synthesis.

Hileman ET, King RB, Adamski JM, Anton TG, Bailey RL, Baker SJ, Bieser ND, Bell TA Jr, Bissell KM, Bradke DR, Campa H 3rd, Casper GS, Cedar K, Cross MD, DeGregorio BA, Dreslik MJ, Faust LJ, Harvey DS, Hay RW, Jellen BC, Johnson BD, Johnson G, Kiel BD, Kingsbury BA, Kowalski MJ, Lee YM, Lentini AM, Marshall JC, Mauger D, Moore JA, Paloski RA, Phillips CA, Pratt PD, Preney T, Prior KA, Promaine A, Redmer M, Reinert HK, Rouse JD, Shoemaker KT, Sutton S, VanDeWalle TJ, Weatherhead PJ, Wynn D, Yagi A.

PLoS One. 2017 Feb 14;12(2):e0172011. doi: 10.1371/journal.pone.0172011. eCollection 2017.

21.

Rapid and fulminant leptomeningeal spread following radiotherapy in diffuse intrinsic pontine glioma.

Tinkle CL, Orr BA, Lucas JT Jr, Klimo P, Patay Z, Baker SJ, Broniscer A, Qaddoumi I.

Pediatr Blood Cancer. 2017 Aug;64(8). doi: 10.1002/pbc.26416. Epub 2017 Jan 13.

22.

PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation.

Zhu G, Rankin SL, Larson JD, Zhu X, Chow LM, Qu C, Zhang J, Ellison DW, Baker SJ.

Cancer Res. 2017 Jan 1;77(1):123-133. doi: 10.1158/0008-5472.CAN-16-1991. Epub 2016 Nov 4.

23.

Microsatellite and major histocompatibility complex variation in an endangered rattlesnake, the Eastern Massasauga (Sistrurus catenatus).

Jaeger CP, Duvall MR, Swanson BJ, Phillips CA, Dreslik MJ, Baker SJ, King RB.

Ecol Evol. 2016 May 17;6(12):3991-4003. doi: 10.1002/ece3.2159. eCollection 2016 Jun.

24.

Pediatric high-grade glioma: biologically and clinically in need of new thinking.

Jones C, Karajannis MA, Jones DTW, Kieran MW, Monje M, Baker SJ, Becher OJ, Cho YJ, Gupta N, Hawkins C, Hargrave D, Haas-Kogan DA, Jabado N, Li XN, Mueller S, Nicolaides T, Packer RJ, Persson AI, Phillips JJ, Simonds EF, Stafford JM, Tang Y, Pfister SM, Weiss WA.

Neuro Oncol. 2017 Feb 1;19(2):153-161. doi: 10.1093/neuonc/now101. Review.

25.

A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling.

Athuluri-Divakar SK, Vasquez-Del Carpio R, Dutta K, Baker SJ, Cosenza SC, Basu I, Gupta YK, Reddy MV, Ueno L, Hart JR, Vogt PK, Mulholland D, Guha C, Aggarwal AK, Reddy EP.

Cell. 2016 Apr 21;165(3):643-55. doi: 10.1016/j.cell.2016.03.045.

26.

Detecting PTEN and PI3K Signaling in Brain.

Zhu G, Baker SJ.

Methods Mol Biol. 2016;1388:53-62. doi: 10.1007/978-1-4939-3299-3_5.

27.

HEMATOLOGY IN AN EASTERN MASSASAUGA (SISTRURUS CATENATUS) POPULATION AND THE EMERGENCE OF OPHIDIOMYCES IN ILLINOIS, USA.

Allender MC, Phillips CA, Baker SJ, Wylie DB, Narotsky A, Dreslik MJ.

J Wildl Dis. 2016 Apr 28;52(2):258-69. doi: 10.7589/2015-02-049. Epub 2016 Mar 11.

PMID:
26967140
28.

Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology.

Qaddoumi I, Orisme W, Wen J, Santiago T, Gupta K, Dalton JD, Tang B, Haupfear K, Punchihewa C, Easton J, Mulder H, Boggs K, Shao Y, Rusch M, Becksfort J, Gupta P, Wang S, Lee RP, Brat D, Peter Collins V, Dahiya S, George D, Konomos W, Kurian KM, McFadden K, Serafini LN, Nickols H, Perry A, Shurtleff S, Gajjar A, Boop FA, Klimo PD Jr, Mardis ER, Wilson RK, Baker SJ, Zhang J, Wu G, Downing JR, Tatevossian RG, Ellison DW.

Acta Neuropathol. 2016 Jun;131(6):833-45. doi: 10.1007/s00401-016-1539-z. Epub 2016 Jan 25.

29.

Pediatric gliomas as neurodevelopmental disorders.

Baker SJ, Ellison DW, Gutmann DH.

Glia. 2016 Jun;64(6):879-95. doi: 10.1002/glia.22945. Epub 2015 Dec 6. Review.

30.

Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy.

Roy A, Skibo J, Kalume F, Ni J, Rankin S, Lu Y, Dobyns WB, Mills GB, Zhao JJ, Baker SJ, Millen KJ.

Elife. 2015 Dec 3;4. pii: e12703. doi: 10.7554/eLife.12703.

31.

Arid1a inactivation in an Apc- and Pten-defective mouse ovarian cancer model enhances epithelial differentiation and prolongs survival.

Zhai Y, Kuick R, Tipton C, Wu R, Sessine M, Wang Z, Baker SJ, Fearon ER, Cho KR.

J Pathol. 2016 Jan;238(1):21-30. doi: 10.1002/path.4599. Epub 2015 Sep 15.

32.

Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas.

Divakar SK, Ramana Reddy MV, Cosenza SC, Baker SJ, Perumal D, Antonelli AC, Brody J, Akula B, Parekh S, Reddy EP.

Leukemia. 2016 Jan;30(1):86-93. doi: 10.1038/leu.2015.185. Epub 2015 Jul 15.

33.

The PM10 fraction of road dust in the UK and India: Characterization, source profiles and oxidative potential.

Pant P, Baker SJ, Shukla A, Maikawa C, Godri Pollitt KJ, Harrison RM.

Sci Total Environ. 2015 Oct 15;530-531:445-452. doi: 10.1016/j.scitotenv.2015.05.084. Epub 2015 May 29.

PMID:
26033216
34.

CONSERTING: integrating copy-number analysis with structural-variation detection.

Chen X, Gupta P, Wang J, Nakitandwe J, Roberts K, Dalton JD, Parker M, Patel S, Holmfeldt L, Payne D, Easton J, Ma J, Rusch M, Wu G, Patel A, Baker SJ, Dyer MA, Shurtleff S, Espy S, Pounds S, Downing JR, Ellison DW, Mullighan CG, Zhang J.

Nat Methods. 2015 Jun;12(6):527-30. doi: 10.1038/nmeth.3394. Epub 2015 May 4.

35.

Activated mutant p110α causes endometrial carcinoma in the setting of biallelic Pten deletion.

Joshi A, Miller C Jr, Baker SJ, Ellenson LH.

Am J Pathol. 2015 Apr;185(4):1104-13. doi: 10.1016/j.ajpath.2014.12.019. Epub 2015 Feb 16.

36.

Cell of origin for malignant gliomas and its implication in therapeutic development.

Zong H, Parada LF, Baker SJ.

Cold Spring Harb Perspect Biol. 2015 Jan 29;7(5). pii: a020610. doi: 10.1101/cshperspect.a020610. Review.

37.

Lipopolysaccharide inhibits or accelerates biomedical titanium corrosion depending on environmental acidity.

Yu F, Addison O, Baker SJ, Davenport AJ.

Int J Oral Sci. 2015 Sep 14;7(3):179-86. doi: 10.1038/ijos.2014.76.

38.

Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma.

Misuraca KL, Barton KL, Chung A, Diaz AK, Conway SJ, Corcoran DL, Baker SJ, Becher OJ.

Acta Neuropathol Commun. 2014 Oct 21;2:134. doi: 10.1186/s40478-014-0134-6.

39.

Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma.

Jones C, Baker SJ.

Nat Rev Cancer. 2014 Oct;14(10). doi: 10.1038/nrc3811. Review.

40.

The genetic signatures of pediatric high-grade glioma: no longer a one-act play.

Diaz AK, Baker SJ.

Semin Radiat Oncol. 2014 Oct;24(4):240-7. doi: 10.1016/j.semradonc.2014.06.003. Review.

41.

Accuracy and consistency of grass pollen identification by human analysts using electron micrographs of surface ornamentation.

Mander L, Baker SJ, Belcher CM, Haselhorst DS, Rodriguez J, Thorn JL, Tiwari S, Urrego DH, Wesseln CJ, Punyasena SW.

Appl Plant Sci. 2014 Aug 12;2(8). pii: apps.1400031. doi: 10.3732/apps.1400031. eCollection 2014 Aug.

42.

Discovery of (R)-1-(7-chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea (A-1165442): a temperature-neutral transient receptor potential vanilloid-1 (TRPV1) antagonist with analgesic efficacy.

Voight EA, Gomtsyan AR, Daanen JF, Perner RJ, Schmidt RG, Bayburt EK, DiDomenico S, McDonald HA, Puttfarcken PS, Chen J, Neelands TR, Bianchi BR, Han P, Reilly RM, Franklin PH, Segreti JA, Nelson RA, Su Z, King AJ, Polakowski JS, Baker SJ, Gauvin DM, Lewis LR, Mikusa JP, Joshi SK, Faltynek CR, Kym PR, Kort ME.

J Med Chem. 2014 Sep 11;57(17):7412-24. doi: 10.1021/jm500916t. Epub 2014 Aug 21.

PMID:
25100568
43.

A unified nomenclature and amino acid numbering for human PTEN.

Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, Davé V, den Hertog J, Devreotes P, Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, Jiang X, Lee SR, Lösche M, Malaney P, Matias-Guiu X, Molina M, Pandolfi PP, Parsons R, Pinton P, Rivas C, Rocha RM, Rodríguez MS, Ross AH, Serrano M, Stambolic V, Stiles B, Suzuki A, Tan SS, Tonks NK, Trotman LC, Wolff N, Woscholski R, Wu H, Leslie NR.

Sci Signal. 2014 Jul 1;7(332):pe15. doi: 10.1126/scisignal.2005560.

44.

The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes.

Huether R, Dong L, Chen X, Wu G, Parker M, Wei L, Ma J, Edmonson MN, Hedlund EK, Rusch MC, Shurtleff SA, Mulder HL, Boggs K, Vadordaria B, Cheng J, Yergeau D, Song G, Becksfort J, Lemmon G, Weber C, Cai Z, Dang J, Walsh M, Gedman AL, Faber Z, Easton J, Gruber T, Kriwacki RW, Partridge JF, Ding L, Wilson RK, Mardis ER, Mullighan CG, Gilbertson RJ, Baker SJ, Zambetti G, Ellison DW, Zhang J, Downing JR.

Nat Commun. 2014 Apr 8;5:3630. doi: 10.1038/ncomms4630.

45.

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.

Wu G, Diaz AK, Paugh BS, Rankin SL, Ju B, Li Y, Zhu X, Qu C, Chen X, Zhang J, Easton J, Edmonson M, Ma X, Lu C, Nagahawatte P, Hedlund E, Rusch M, Pounds S, Lin T, Onar-Thomas A, Huether R, Kriwacki R, Parker M, Gupta P, Becksfort J, Wei L, Mulder HL, Boggs K, Vadodaria B, Yergeau D, Russell JC, Ochoa K, Fulton RS, Fulton LL, Jones C, Boop FA, Broniscer A, Wetmore C, Gajjar A, Ding L, Mardis ER, Wilson RK, Taylor MR, Downing JR, Ellison DW, Zhang J, Baker SJ.

Nat Genet. 2014 May;46(5):444-450. doi: 10.1038/ng.2938. Epub 2014 Apr 6.

46.

B-myb is an essential regulator of hematopoietic stem cell and myeloid progenitor cell development.

Baker SJ, Ma'ayan A, Lieu YK, John P, Reddy MV, Chen EY, Duan Q, Snoeck HW, Reddy EP.

Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3122-7. doi: 10.1073/pnas.1315464111. Epub 2014 Feb 10.

47.

Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5).

Reddy MV, Akula B, Cosenza SC, Athuluridivakar S, Mallireddigari MR, Pallela VR, Billa VK, Subbaiah DR, Bharathi EV, Vasquez-Del Carpio R, Padgaonkar A, Baker SJ, Reddy EP.

J Med Chem. 2014 Feb 13;57(3):578-99. doi: 10.1021/jm401073p. Epub 2014 Jan 24.

48.

Surgical versus nonsurgical management for overweight dogs with cranial cruciate ligament rupture.

Baker SJ, Baker GJ.

J Am Vet Med Assoc. 2013 Aug 15;243(4):479. No abstract available.

PMID:
24059000
49.

Driving efficient flow: three best-practice models.

Baker SJ, Shupe R, Smith D.

J Emerg Nurs. 2013 Sep;39(5):481-4. doi: 10.1016/j.jen.2013.02.008. Review. No abstract available.

PMID:
23998225
50.

Understanding the temporal sequence of genetic events that lead to prostate cancer progression and metastasis.

Baker SJ, Reddy EP.

Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14819-20. doi: 10.1073/pnas.1313997110. Epub 2013 Aug 30. No abstract available.

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